| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B E Garrett, R R Griffith. The role of dopamine in the behavioral effects of caffeine in animals and humans. Pharmacology, biochemistry, and behavior. vol 57. issue 3. 1997-10-23. PMID:9218278. |
recently, caffeine has been shown to enhance dopaminergic activity, presumably by competitive antagonism at adenosine receptors that are colocalized and interact functionally with dopamine receptors. |
1997-10-23 |
2023-08-12 |
human |
| B E Garrett, R R Griffith. The role of dopamine in the behavioral effects of caffeine in animals and humans. Pharmacology, biochemistry, and behavior. vol 57. issue 3. 1997-10-23. PMID:9218278. |
thus, caffeine, as a competitive antagonist at adenosine receptors, may produce its behavioral effects by removing the negative modulatory effects of adenosine from dopamine receptors, thus stimulating dopaminergic activity. |
1997-10-23 |
2023-08-12 |
human |
| J Balthazart, C Castagna, G F Bal. Differential effects of D1 and D2 dopamine-receptor agonists and antagonists on appetitive and consummatory aspects of male sexual behavior in Japanese quail. Physiology & behavior. vol 62. issue 3. 1997-10-23. PMID:9272666. |
pharmacological studies in japanese quail based on behavioral tests with a variety of dopaminergic compounds suggest that the activation of d2 dopamine receptors inhibits, and the activation of d1 dopamine receptors enhances, appetitive and consummatory components of male sexual behavior. |
1997-10-23 |
2023-08-12 |
Not clear |
| S Sanyal, H H Van To. Review the role of dopamine D4 receptors in schizophrenia and antipsychotic action. Journal of psychiatric research. vol 31. issue 2. 1997-10-23. PMID:9278187. |
for the past 20 years the most enduring explanation for schizophrenia has been the dopamine hypothesis, which proposes that the dopaminergic system is overactive in this widespread disease. |
1997-10-23 |
2023-08-12 |
Not clear |
| R H Farkas, P Y Chien, S Nakajima, Y Nakajim. Neurotensin and dopamine D2 activation oppositely regulate the same K+ conductance in rat midbrain dopaminergic neurons. Neuroscience letters. vol 231. issue 1. 1997-10-23. PMID:9280158. |
neurotensin and dopamine d2 activation oppositely regulate the same k+ conductance in rat midbrain dopaminergic neurons. |
1997-10-23 |
2023-08-12 |
rat |
| R H Farkas, P Y Chien, S Nakajima, Y Nakajim. Neurotensin and dopamine D2 activation oppositely regulate the same K+ conductance in rat midbrain dopaminergic neurons. Neuroscience letters. vol 231. issue 1. 1997-10-23. PMID:9280158. |
midbrain dopaminergic neurons are excited by neurotensin (nt) and inhibited by dopamine. |
1997-10-23 |
2023-08-12 |
rat |
| D A Loeffler, A J DeMaggio, P L Juneau, M K Havaich, P A LeWit. Effects of enhanced striatal dopamine turnover in vivo on glutathione oxidation. Clinical neuropharmacology. vol 17. issue 4. 1997-10-23. PMID:9316685. |
in parkinson's disease (pd), a compensatory increase in dopamine (da) turnover occurs in the remaining nigrostriatal dopaminergic neurons, resulting in greater exposure of each neuron to hydrogen peroxide (h2o2) derived from oxidative deamination of da. |
1997-10-23 |
2023-08-12 |
rat |
| C D Richards, T Shiroyama, S T Kita. Electrophysiological and immunocytochemical characterization of GABA and dopamine neurons in the substantia nigra of the rat. Neuroscience. vol 80. issue 2. 1997-10-17. PMID:9284356. |
the neurons recorded in the pars reticulata were identified as either gaba or dopamine neurons: neurons were considered to be gaba neurons if they were immunopositive for glutamate decarboxylase, whereas those neurons which were immunopositive for tyrosine hydroxylase were considered to be dopaminergic. |
1997-10-17 |
2023-08-12 |
rat |
| S Inoue, M Susukida, K Ikeda, K Murase, K Hayash. Dopaminergic transmitter up-regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) synthesis in mouse astrocytes in culture. Biochemical and biophysical research communications. vol 238. issue 2. 1997-10-16. PMID:9299533. |
using this eia system, we examined the effect of dopaminergic transmitters such as dopamine and epinephrine on bdnf synthesis in mouse astrocytes in culture. |
1997-10-16 |
2023-08-12 |
mouse |
| H Kojima, Y Abiru, K Sakajiri, K Watabe, N Ohishi, M Takamori, H Hatanaka, K Yag. Adenovirus-mediated transduction with human glial cell line-derived neurotrophic factor gene prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopamine depletion in striatum of mouse brain. Biochemical and biophysical research communications. vol 238. issue 2. 1997-10-16. PMID:9299553. |
the mice that had received our constructed virus had significantly higher dopamine levels in their striatum, demonstrating that our radv expressing hgdnf has therapeutic potential to protect the nigrostriatal dopaminergic neurons in vivo. |
1997-10-16 |
2023-08-12 |
mouse |
| E A Kordysh, Y Herishanu, J R Goldsmit. Chemical exposures and Parkinson's disease in residents of three Negev kibbutzim. Environmental research. vol 73. issue 1-2. 1997-10-15. PMID:9311542. |
literature data on pd pathogenesis have been compared with common pathogenetic pathways to xenobiotics effects; the following neurotoxic mechanisms, besides individual sensitivity, have been suggested: (1) impairment of the protective role of the substantia nigra against toxicants by binding of chemicals to melanin; (2) oxidative stress induction, including glutathione reduction, impaired calcium metabolism, and alteration of cytochrome p-450 activity; (3) blockade of iron chelators because of structural similarities to them or their precursors; (4) mediation of the production of endogenous dopaminergic neurotoxins, such as trichloroharmanes or isoquinolines; (5) blockade of dopamine receptors because of their resemblance to chemicals with affinity to these receptors; (6) stimulation of prostaglandin-h synthase and monooxygenase activity; and (7) stimulation of autoimmune processes and creation of autoimmunity to structures of the dopaminergic system caused by chemical similarity. |
1997-10-15 |
2023-08-12 |
Not clear |
| F Gono. Prolonged and extrasynaptic excitatory action of dopamine mediated by D1 receptors in the rat striatum in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 15. 1997-10-03. PMID:9221793. |
for this purpose dopamine (da) release was evoked in the striatum of anesthetized rats by train electrical stimulations of the medial forebrain bundle (one to four pulses at 15 hz), which mimicked the spontaneous activity of dopaminergic neurons. |
1997-10-03 |
2023-08-12 |
rat |
| T G Hastings, M J Zigmon. Loss of dopaminergic neurons in parkinsonism: possible role of reactive dopamine metabolites. Journal of neural transmission. Supplementum. vol 49. 1997-10-03. PMID:9266419. |
loss of dopaminergic neurons in parkinsonism: possible role of reactive dopamine metabolites. |
1997-10-03 |
2023-08-12 |
Not clear |
| M J Nirenberg, J Chan, A Pohorille, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 18. 1997-10-03. PMID:9278525. |
the dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens. |
1997-10-03 |
2023-08-12 |
Not clear |
| A H Cincotta, E Tozzo, P W Scislowsk. Bromocriptine/SKF38393 treatment ameliorates obesity and associated metabolic dysfunctions in obese (ob/ob) mice. Life sciences. vol 61. issue 10. 1997-10-03. PMID:9296333. |
it has been postulated that dopaminergic activities comprise a major functional component of a central regulatory system for metabolism which can be manipulated by dopamine modulating drugs. |
1997-10-03 |
2023-08-12 |
mouse |
| M Moro, C Maraschini, F Cavagnin. Dopamine infusion enhances the adrenocorticotropic hormone and cortisol response to metoclopramide in hyperprolactinemic patients but not in normal subjects. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 11. issue 3. 1997-10-02. PMID:9209895. |
based on the facts that prolactin and adrenocorticotropic hormone (acth) each seem to influence the secretion of the other, that dopamine is the established inhibitory factor for prolactin secretion and negatively modulates acth release, and finally that alterations of the central dopaminergic tone have been postulated in tumorous hyperprolactinemia, we studied the effects of pharmacological manipulations of the dopaminergic system on acth and cortisol secretion in patients bearing a prolactinoma and in normal subjects. |
1997-10-02 |
2023-08-12 |
human |
| M Moro, C Maraschini, F Cavagnin. Dopamine infusion enhances the adrenocorticotropic hormone and cortisol response to metoclopramide in hyperprolactinemic patients but not in normal subjects. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 11. issue 3. 1997-10-02. PMID:9209895. |
these findings support the concept of an inhibitory role exerted by dopamine and are compatible with a stimulatory influence exerted by prolactin on corticotropin-releasing hormone and acth secretion, and also favor the view of a reduced central dopaminergic tone in patients with tumorous hyperprolactinemia. |
1997-10-02 |
2023-08-12 |
human |
| R Bossé, F Fumagalli, M Jaber, B Giros, R R Gainetdinov, W C Wetsel, C Missale, M G Caro. Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. vol 19. issue 1. 1997-10-02. PMID:9247269. |
deletion of the dopamine transporter (dat) results in increased dopaminergic tone, anterior pituitary hypoplasia, dwarfism, and an inability to lactate. |
1997-10-02 |
2023-08-12 |
mouse |
| A Heller, H Choi, L Wo. Regulation of developing dopaminergic axonal arbor size in three-dimensional reaggregate tissue culture. The Journal of comparative neurology. vol 384. issue 3. 1997-10-02. PMID:9254032. |
after 3 weeks in culture, dopamine levels increased linearly and proportionally to dopaminergic cell number over a 25-fold relative increase in target cell availability. |
1997-10-02 |
2023-08-12 |
Not clear |
| I Ushijima, M Kawano, H Kaneyuki, M Suetsugi, K Usami, H Hirano, Y Mizuki, M Yamad. Dopaminergic and cholinergic interaction in cataleptic responses in mice. Pharmacology, biochemistry, and behavior. vol 58. issue 1. 1997-09-30. PMID:9264077. |
dopamine d1 and d2 receptors may interact in a synergistic fashion on dopaminergic systems, but act independently of each other in influencing other system such as cholinergic neurons. |
1997-09-30 |
2023-08-12 |
mouse |