Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Vrinda Jain, Phillip J M Liang, Sushmitha Raja, Meena Mikhael, Morven A Camero. Light activation of the dopaminergic system occurs after eye-opening in the mouse retina. Frontiers in ophthalmology. vol 3. 2024-07-10. PMID:38983102. |
dopaminergic amacrine cells in the adult retina release dopamine in response to light stimulation, however, the light-induced activity of these cells in during postnatal development is not known. |
2024-07-10 |
2024-07-12 |
mouse |
Vrinda Jain, Phillip J M Liang, Sushmitha Raja, Meena Mikhael, Morven A Camero. Light activation of the dopaminergic system occurs after eye-opening in the mouse retina. Frontiers in ophthalmology. vol 3. 2024-07-10. PMID:38983102. |
our data suggests that dopaminergic cell activation and light-induced dopamine release in the retina is primarily driven by classical photoreceptors after eye-opening. |
2024-07-10 |
2024-07-12 |
mouse |
Miguel Ribeiro, Jonas Campos, Tiffany S Pinho, Belém Sampaio-Marques, Sandra Barata-Antunes, Jorge Ribeiro Cibrão, Ricardo Araújo, Sara Duarte-Silva, Elsa Moreira, Rui A Sousa, Pedro M Costa, António J Salgad. Human platelet lysate supports SH-SY5Y neuroblastoma cell proliferation and differentiation into a dopaminergic-like neuronal phenotype under xenogeneic-free culture conditions. Biotechnology journal. vol 19. issue 7. 2024-07-10. PMID:38987218. |
furthermore, following treatment with retinoic acid (ra) and further stimulation with brain-derived neurotrophic factor (bdnf) and nerve growth factor beta (ngf-β), the percentage of sh-sy5y cells stained positive for dopaminergic neuronal differentiation markers (tyrosine hydroxylase [th] and dopamine transporter [dat]) was higher in hpl or fd-hpl than in fbs, and gene expression of dopaminergic markers th, dat, and dr2 was also detected. |
2024-07-10 |
2024-07-13 |
human |
Sophia J Weber, Alex B Kawa, Alana L Moutier, Madelyn M Beutler, Lara M Koyshman, Cloe D Moreno, Jonathan G Westlake, Amanda M Wunsch, Marina E Wol. Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression of incubation of cocaine craving. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979157. |
however, despite the importance of dopaminergic signaling in the nacc for motivated behavior, little is known about the role that dopamine (da) plays in the incubation of cocaine craving. |
2024-07-09 |
2024-07-12 |
rat |
Dev Desai, Jekee Patel, Falak Saiyed, Himarshi Upadhyay, Prashant Kariya, Jitendra Pate. A Literature Review on Holistic Well-Being and Dopamine Fasting: An Integrated Approach. Cureus. vol 16. issue 6. 2024-07-06. PMID:38966464. |
popularly known as dopaminergic detox or dopamine fasting, it is a concept that aims at reducing dependence on instant satisfaction gratification and overstimulation to attain mental clarity, lessen anxiety, and be able to enjoy everyday events again. |
2024-07-06 |
2024-07-08 |
Not clear |
Muhammad Abdullah, Shih-Hsien Lin, Li-Chung Huang, Nan-Tsing Chiu, Yen Kuang Yan. Fat loss and muscle gain: The possible role of striatal dopaminergic tone in determining the efficacy of physical exercise. Journal of the Formosan Medical Association = Taiwan yi zhi. 2024-07-04. PMID:38965009. |
striatal dopaminergic tone was assessed by measuring dopamine transporter availability using technetium-99 m labelled tropane derivative, [99mtc]trodat-1 (trodat), single-photon emission computed tomography, and body composition (fat and muscles mass) was analysed using bioelectrical impedance. |
2024-07-04 |
2024-07-11 |
Not clear |
Charltien Long, Kwang Lee, Long Yang, Theresia Dafalias, Alexander K Wu, Sotiris C Masmanidi. Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling. Nature neuroscience. 2024-07-03. PMID:38961230. |
it is thought that dopaminergic neurons drive certain behaviors by rapidly modulating striatal spiking activity; however, a view has emerged that only artificially high (that is, supra-physiological) dopamine signals alter behavior on fast timescales. |
2024-07-03 |
2024-07-10 |
mouse |
Joohyun An, Minkyu Shin, Geunyoung Beak, Jinho Yoon, Seewoo Kim, Hyeon-Yeol Cho, Jeong-Woo Cho. Drug Evaluation of Parkinson's Disease Patient-Derived Midbrain Organoids Using Mesoporous Au Nanodot-Patterned 3D Concave Electrode. ACS sensors. 2024-07-02. PMID:38954790. |
after the treatment of pd midbrain organoids with levodopa, the drug for pd, the increase in dopamine level was detected due to the activation of dopaminergic neurons by the drug. |
2024-07-02 |
2024-07-06 |
human |
Reem M Gahtani, Shoaib Shoaib, Umme Hani, R Jayachithra, Mohammad N Alomary, Waseem Chauhan, Roshan Jahan, Saba Tufail, Mohammad Azam Ansar. Combating Parkinson's Disease with Plant-Derived Polyphenols: Targeting Oxidative Stress and Neuroinflammation. Neurochemistry international. 2024-07-01. PMID:38950626. |
dopamine metabolism, mitochondrial dysfunction, and neuroinflammation in dopaminergic neurons have been implicated in the pathogenesis of parkinson's disease. |
2024-07-01 |
2024-07-04 |
Not clear |
Chloé Halfhide, Tommie L Cammarano, Kevin A Anderson, Stefani M Galik, Julien Rossignol, Gary L Dunbar, Michael I Sandstro. Using Microdialysis to Monitor Dopaminergic Support of Limb-Use Control Following Mesencephalic Neurosphere Transplantation in a Rodent Model of Parkinson's Disease. Behavioural brain research. 2024-06-30. PMID:38945302. |
our laboratory previously demonstrated that transplanted dopaminergic cells can elicit skilled movement recovery known to depend on phasic dopamine release. |
2024-06-30 |
2024-07-03 |
human |
Md Reyaz Alam, Vaishali Dobhal, Shamsher Sing. Neuroprotective potential of solanesol against tramadol induced zebrafish model of Parkinson's disease: insights from neurobehavioral, molecular, and neurochemical evidence. Drug and chemical toxicology. 2024-06-28. PMID:38938099. |
parkinson's disease (pd) is a prevalent neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) and subsequent depletion of dopamine in the striatum. |
2024-06-28 |
2024-06-30 |
human |
Sandeep Sathyanandan Nair, Srinivasa Chakravarth. A Computational Model of Deep Brain Stimulation for Parkinson's Disease Tremor and Bradykinesia. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928620. |
the most common approach in managing the symptoms is replenishing the lost dopamine in the form of taking dopaminergic medications such as levodopa, despite its long-term complications. |
2024-06-27 |
2024-06-29 |
Not clear |
Andrew Lian. Assessing gait dysfunction severity in Parkinson's Disease using 2-Stream Spatial-Temporal Neural Network. Journal of biomedical informatics. 2024-06-26. PMID:38925280. |
pd primarily impacts dopaminergic neurons in the brain's substantia nigra, resulting in dopamine deficiency and gait impairments such as bradykinesia and rigidity. |
2024-06-26 |
2024-06-29 |
Not clear |
Stephanie M Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Oluwatofunmi Oteju, Marzieh Daniali, Joanna A Canagarajah, Teresa LuPone, Krisna Mompho, Kaitlyn Runner, Emily Nickoloff-Bybel, Benjamin Li, Meng Niu, Johannes C M Schlachetzki, Howard S Fox, Peter J Gaskil. Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915663. |
finally, using hiv as an example of a chronic inflammatory disease that is substantively worsened by comorbid substance use disorders (suds) that impact dopaminergic signaling, we show increased effects of dopamine on inflammasome activation and il-1β in the presence of hiv in both human macrophages and microglia. |
2024-06-25 |
2024-06-27 |
human |
Vittorio Calabrese, Naomi Osakabe, Foziya Khan, Uwe Wenzel, Sergio Modafferi, Lidia Nicolosi, Tilman Fritsch, Ursula M Jacob, Ali S Abdelhameed, Luay Rasha. Frankincense: A neuronutrient to approach Parkinson's disease treatment. Open medicine (Warsaw, Poland). vol 19. issue 1. 2024-06-24. PMID:38911256. |
parkinson's disease (pd), characterized by tremor, slowness of movement, stiffness, and poor balance, is due to a significant loss of dopaminergic neurons in the substantia nigra pars compacta and dopaminergic nerve terminals in the striatum with deficit of dopamine. |
2024-06-24 |
2024-06-26 |
Not clear |
Jonathan Sackner-Bernstei. Rethinking Parkinson's disease: could dopamine reduction therapy have clinical utility? Journal of neurology. 2024-06-21. PMID:38904783. |
the literature suggests the potential for toxicity of dopamine and its metabolites, perhaps more relevant given the recent evidence for elevated cytosolic dopamine levels in the dopaminergic neurons of people with parkinson's. |
2024-06-21 |
2024-06-23 |
Not clear |
Jonathan Sackner-Bernstei. Rethinking Parkinson's disease: could dopamine reduction therapy have clinical utility? Journal of neurology. 2024-06-21. PMID:38904783. |
to understand the relevance of these data, multiple investigations are reviewed that tested dopamine reduction therapy as an alternative to dopaminergic agents. |
2024-06-21 |
2024-06-23 |
Not clear |
Jonathan Sackner-Bernstei. Rethinking Parkinson's disease: could dopamine reduction therapy have clinical utility? Journal of neurology. 2024-06-21. PMID:38904783. |
if clinical data are positive, it could warrant reconsideration of our disease model and treatment strategies, including a shift from dopaminergic to dopamine reduction treatment of the disease. |
2024-06-21 |
2024-06-23 |
Not clear |
Kielen R Zuurbier, Rene Solano Fonseca, Sonja L B Arneaud, Lexus Tatge, Gupse Otuzoglu, Jordan M Wall, Peter M Dougla. Cytosolic dopamine determines hypersensitivity to blunt force trauma. iScience. vol 27. issue 6. 2024-06-17. PMID:38883817. |
while dopaminergic neurons normally maintain dopamine in a functional and benign state, trauma-induced subcellular redox imbalances elicit dopamine-dependent cytotoxicity. |
2024-06-17 |
2024-06-19 |
Not clear |
Sofia Corrêa Valladão, Angela Patricia França, Pablo Pandolfo, Alexandre Dos Santos-Rodrigue. Adenosinergic System and Nucleoside Transporters in Attention Deficit Hyperactivity Disorder: Current Findings. Neuroscience and biobehavioral reviews. 2024-06-16. PMID:38880409. |
dopamine receptors and transporters are not solely implicated in this imbalance, as evidence indicates that the dopaminergic signaling is modulated by adenosine activity. |
2024-06-16 |
2024-06-19 |
Not clear |