| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Breana Channer, Stephanie M Matt, Emily A Nickoloff-Bybel, Vasiliki Pappa, Yash Agarwal, Jason Wickman, Peter J Gaskil. Dopamine, Immunity, and Disease. Pharmacological reviews. vol 75. issue 1. 2023-02-09. PMID:36757901. |
most types of immune cells express dopamine receptors and other dopaminergic proteins, and many immune cells take up, produce, store, and/or release dopamine, suggesting that dopaminergic immunomodulation is important for immune function. |
2023-02-09 |
2023-08-14 |
human |
| Breana Channer, Stephanie M Matt, Emily A Nickoloff-Bybel, Vasiliki Pappa, Yash Agarwal, Jason Wickman, Peter J Gaskil. Dopamine, Immunity, and Disease. Pharmacological reviews. vol 75. issue 1. 2023-02-09. PMID:36757901. |
this review comprehensively assesses the current knowledge of dopaminergic immunomodulation and the role of dopamine in disease pathogenesis at the cellular and tissue level. |
2023-02-09 |
2023-08-14 |
human |
| Nicole K Brown, Joy K Roche, Charlene B Farmer, Rosalinda C Robert. Evidence for upregulation of excitatory synaptic transmission in the substantia nigra in Schizophrenia: a postmortem ultrastructural study. Journal of neural transmission (Vienna, Austria : 1996). 2023-02-03. PMID:36735096. |
the dopamine hypothesis of schizophrenia suggests that psychotic symptoms originate from dysregulation of dopaminergic activity, which may be controlled by upstream innervation. |
2023-02-03 |
2023-08-14 |
human |
| Tahereh Sohrabi, Behnaz Mirzaei-Behbahani, Ramin Zadali, Mitra Pirhaghi, Ludmilla A Morozova-Roche, Ali Akbar Merata. Common Mechanisms Underlying α-Synuclein-Induced Mitochondrial Dysfunction in Parkinson's Disease. Journal of molecular biology. 2023-02-03. PMID:36736886. |
parkinson's disease (pd) is the most common neurological movement disorder characterized by the selective and irreversible loss of dopaminergic neurons in substantia nigra pars compacta resulting in dopamine deficiency in the striatum. |
2023-02-03 |
2023-08-14 |
Not clear |
| Liping Zhou, Deqiang Han, Xingzhe Wang, Zhiguo Che. Probiotic Formulation VSL#3 Interacts with Mesenchymal Stromal Cells To Protect Dopaminergic Neurons via Centrally and Peripherally Suppressing NOD-Like Receptor Protein 3 Inflammasome-Mediated Inflammation in Parkinson's Disease Mice. Microbiology spectrum. 2023-02-02. PMID:36728426. |
hmscs, vsl#3 alone, and their combination markedly ameliorated the decreased striatal dopamine content, loss of dopaminergic neurons in the substantia nigra, increased levels of proinflammatory cytokines in serum, as well as tumor necrosis factor alpha (tnf-α) and interleukin-1β (il-1β) mrnas in striatum and peripheral tissues induced by mptp. |
2023-02-02 |
2023-08-14 |
mouse |
| Simon Desch, Petra Schweinhardt, Ben Seymour, Herta Flor, Susanne Becke. Evidence for dopaminergic involvement in endogenous modulation of pain relief. eLife. vol 12. 2023-02-01. PMID:36722857. |
we then probed the roles of dopaminergic and opioidergic signaling, both of which are implicated in relief processing, by embedding the task in a double-blinded cross-over design with administration of the dopamine precursor levodopa and the opioid receptor antagonist naltrexone. |
2023-02-01 |
2023-08-14 |
Not clear |
| Brittany Liebenow, Angela Jiang, Emily DiMarco, Thomas Wilson, Mustafa S Siddiqui, Ihtsham Ul Haq, Adrian W Laxton, Stephen B Tatter, Kenneth T Kishid. Intracranial subsecond dopamine measurements during a "sure bet or gamble" decision-making task in patients with alcohol use disorder suggest diminished dopaminergic signals about relief. Neurosurgical focus. vol 54. issue 2. 2023-02-01. PMID:36724520. |
intracranial subsecond dopamine measurements during a "sure bet or gamble" decision-making task in patients with alcohol use disorder suggest diminished dopaminergic signals about relief. |
2023-02-01 |
2023-08-14 |
Not clear |
| Shipra Kartik, Rishi Pal, Manju J Chaudhary, Rajendra Nath, Madhu Kumar, Monika Binwal, D U Bawankul. Neuroprotective role of chloroquine via modulation of autophagy and neuroinflammation in MPTP-induced Parkinson's disease. Inflammopharmacology. 2023-01-30. PMID:36715843. |
cq therapy preserves dopamine levels stable, inhibits tyrosine hydroxylase (th) positive dopaminergic cell death, and lowers oxidative stress. |
2023-01-30 |
2023-08-14 |
mouse |
| Amanda Scanga, Anne-Louise Lafontaine, Marta Kaminsk. An overview of the effects of levodopa and dopaminergic agonists on sleep disorders in Parkinson's disease. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2023-01-30. PMID:36716191. |
levodopa and dopaminergic drugs may have different effects, beneficial or adverse, depending on dosing, method of administration and differential effects on the different dopamine receptors. |
2023-01-30 |
2023-08-14 |
Not clear |
| Yuka Nago-Iwashita, Yuki Moriya, Satoshi Hara, Ryohei Ogawa, Rina Aida, Katsuya Miyajima, Takenobu Shimura, Shin-Ichi Muramatsu, Soichiro Ide, Kazutaka Ikeda, Hiroshi Ichinos. Overexpression of tyrosine hydroxylase in dopaminergic neurons increased sensitivity to methamphetamine. Neurochemistry international. 2023-01-28. PMID:36709046. |
dopaminergic neurons are deeply involved in addiction, and tyrosine hydroxylase (th) catalyzes the first and rate-limiting step of the biosynthesis of dopamine (da). |
2023-01-28 |
2023-08-14 |
mouse |
| Reham M Essam, Esraa A Kandi. p-CREB and p-DARPP-32 orchestrating the modulatory role of cAMP/PKA signaling pathway enhanced by Roflumilast in rotenone-induced Parkinson's disease in rats. Chemico-biological interactions. 2023-01-27. PMID:36706892. |
the camp was shown to play a vital role in dopamine (da) signaling besides maintaining the plasticity of dopaminergic neurons as well as protecting them from inflammation and oxidative stress-mediated death. |
2023-01-27 |
2023-08-14 |
rat |
| Reham M Essam, Esraa A Kandi. p-CREB and p-DARPP-32 orchestrating the modulatory role of cAMP/PKA signaling pathway enhanced by Roflumilast in rotenone-induced Parkinson's disease in rats. Chemico-biological interactions. 2023-01-27. PMID:36706892. |
the beneficial effect of roflumilast was mediated through inhibition of striatal pde4 with consequent activation of camp-dependent protein kinase a (pka) signaling pathways, including the camp response element-binding protein (creb) pathway and dopamine and camp-regulated phosphoprotein 32,000 (darpp-32) pathway that is essential for maintaining dopaminergic function. |
2023-01-27 |
2023-08-14 |
rat |
| Barbara Pavan, Anna Bianchi, Giada Botti, Luca Ferraro, Maria Chiara Valerii, Enzo Spisni, Alessandro Dalpia. Pharmacokinetic and Permeation Studies in Rat Brain of Natural Compounds Led to Investigate Eugenol as Direct Activator of Dopamine Release in PC12 Cells. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36675321. |
eugenol was therefore recruited for in vitro studies of viability and time-/dose-dependent dopamine release in neuronal differentiated pc12 cells (a recognized cellular model mimicking dopaminergic neurons), evidencing its ability to increase cell viability and to induce dopamine release according to a u-shaped time-course curve. |
2023-01-21 |
2023-08-14 |
rat |
| Ranjithkumar Chellian, Azin Behnood-Rod, Ryann Wilson, Karen Lin, Grace Wing-Yan King, Adriaan W Bruijnzee. The D1/D2-like receptor antagonist flupentixol and the D2-like receptor antagonist L-741626 decrease operant responding for nicotine and food and locomotor activity in male and female rats. Journal of psychopharmacology (Oxford, England). 2023-01-21. PMID:36680471. |
dopamine plays a role in the reinforcing properties of nicotine, but little is known about the role of dopamine d2-like receptors in nicotine intake and whether there are sex differences in the effects of dopaminergic drugs on nicotine intake. |
2023-01-21 |
2023-08-14 |
rat |
| Ashok Chakraborty, Anil Diwa. Depression and Parkinson's disease: a Chicken-Egg story. AIMS neuroscience. vol 9. issue 4. 2023-01-20. PMID:36660077. |
the underlying pathophysiological process in pd is mainly due to the loss of dopaminergic neural cells and thereby causes the shortage of nigrostriatal dopamine content in them. |
2023-01-20 |
2023-08-14 |
Not clear |
| Samhwan Kim, Seongtak Kang, Jiyun Choe, Cheil Moon, Hongsoo Choi, Jin-Young Kim, Ji-Woong Cho. A Microfluidic System for Investigating Anticipatory Medication Effects on Dopamine Homeostasis in Dopaminergic Cells. Analytical chemistry. 2023-01-19. PMID:36656793. |
a microfluidic system for investigating anticipatory medication effects on dopamine homeostasis in dopaminergic cells. |
2023-01-19 |
2023-08-14 |
Not clear |
| Daniel Kalinowski, Krystyna Bogus-Nowakowska, Anna Kozłowska, Maciej Równia. Dopaminergic and cholinergic modulation of the amygdala is altered in female mice with oestrogen receptor β deprivation. Scientific reports. vol 13. issue 1. 2023-01-17. PMID:36650256. |
the results show that among dopaminergic markers, the expression of tyrosine hydroxylase (th), dopamine transporter (dat) and dopamine d |
2023-01-17 |
2023-08-14 |
mouse |
| Hiroki Kawashima, Yuri Aono, Shigeki Shimba, John L Waddington, Tadashi Saigus. Adolescence as a critical period for nandrolone-induced muscular strength in relation to abuse liability, alone and in conjunction with morphine, using accumbal dopamine efflux in freely moving rats. Synapse (New York, N.Y.). 2023-01-13. PMID:36637118. |
accordingly, possible critical periods for the effects of nandrolone on muscular strength and dopaminergic activity have been investigated, including the effects of chronically administered nandrolone alone and on morphine-induced increases in dopamine efflux in the nucleus accumbens. |
2023-01-13 |
2023-08-14 |
rat |
| Bingxu Huang, Guiqiu Hu, Xiaofeng Zong, Shuo Yang, Dewei He, Xiyu Gao, Dianfeng Li. α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway. International immunopharmacology. vol 115. 2023-01-12. PMID:36634417. |
in this study, our results indicated that α-cyperone ameliorated motor dysfunction, protected dopaminergic neurons, and inhibited the reduction of dopamine and its metabolites in lipopolysaccharide (lps)-induced pd rat model. |
2023-01-12 |
2023-08-14 |
rat |
| Gwen-Jirō Clochard, Aby Mbengue, Clément Mettling, Birane Diouf, Charlotte Faurie, Omar Sene, Emilie Chancerel, Erwan Guichoux, Guillaume Hollard, Michel Raymond, Marc Willinge. The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen. Scientific reports. vol 13. issue 1. 2023-01-12. PMID:36635358. |
despite the involvement of dopamine in the expectation of reward described by neurobiologists, a gwas study was not able to demonstrate a genetic contribution of genes involved in the dopaminergic pathway in risk attitudes and gene candidate studies gave contrasting results. |
2023-01-12 |
2023-08-14 |
Not clear |