| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G L Bernardini, X Gu, D C Germa. Nucleus A10 dopaminergic neurons in inbred mouse strains: firing rate and autoreceptor sensitivity are independent of the number of cells in the nucleus. Brain research bulletin. vol 27. issue 2. 1992-01-13. PMID:1742603. |
inbred mouse strains have different numbers of midbrain dopaminergic neurons; for example, balb/cj mice have 20-25% more neurons than cba/j mice. |
1992-01-13 |
2023-08-11 |
mouse |
| G L Bernardini, X Gu, D C Germa. Nucleus A10 dopaminergic neurons in inbred mouse strains: firing rate and autoreceptor sensitivity are independent of the number of cells in the nucleus. Brain research bulletin. vol 27. issue 2. 1992-01-13. PMID:1742603. |
as the number of cells decrease, for example in parkinson's disease and in animals with midbrain dopaminergic cell lesions, the activity of their remaining cells increases. |
1992-01-13 |
2023-08-11 |
mouse |
| L S Carman, F H Gage, C W Shult. Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain research. vol 553. issue 2. 1991-12-13. PMID:1681983. |
recent work, largely carried out in primate models of parkinson's disease (pd), indicates that residual dopaminergic neurons in the midbrain and their axons to the nucleus accumbens and striatum can be stimulated to sprout collateral axons, reinnervate the striatum, and cause a behavioral recovery. |
1991-12-13 |
2023-08-11 |
human |
| L S Carman, F H Gage, C W Shult. Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain research. vol 553. issue 2. 1991-12-13. PMID:1681983. |
we sought to create a partial lesion model of pd in the rat that would (i) mimic the pattern of cell loss in human patients in early stages of pd, and (ii) permit examination of experimental manipulations that promote sprouting of axons of the surviving dopaminergic cells in the midbrain. |
1991-12-13 |
2023-08-11 |
human |
| S B Blunt, P Jenner, C D Marsde. The effect of L-dopa and carbidopa treatment on the survival of rat fetal dopamine grafts assessed by tyrosine hydroxylase immunohistochemistry and [3H]mazindol autoradiography. Neuroscience. vol 43. issue 1. 1991-11-15. PMID:1681462. |
the effect of treatment with l-3,4-dihydroxyphenylalanine (l-dopa) and carbidopa for five weeks on the survival of rat fetal dopaminergic ventral mesencephalon cells implanted into the denervated striatum of rats with unilateral 6-hydroxydopamine nigrostriatal lesions was assessed. |
1991-11-15 |
2023-08-11 |
rat |
| N N Kudriavtseva, I V Bakshtanovskai. [The neurochemical control of aggression and submission]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 41. issue 3. 1991-11-06. PMID:1681631. |
the dopaminergic system of nucleus accumbens and midbrain are nonspecifically activated in both aggressive and submissive animals. |
1991-11-06 |
2023-08-11 |
mouse |
| N Kolocouris, G B Foscolos, G Fytas, A Sakellariou, C Raftopoulos, Z Papadopoulou-Daïfoti, A Vamvakidè. [Dopamine amides with essential or fundamental fatty acids. Synthesis and pharmacological study]. Annales pharmaceutiques francaises. vol 49. issue 2. 1991-10-28. PMID:1681774. |
the experimental results which are obtained from these derivatives (antagonized or non antagonized hypomotility by neuroleptics in low doses on mice, potentiation of the haloperidol catalepsy or not, on rats) could be compatible with a selective action of these amides on the autoreceptors of the cerebral dopaminergic neurons and with a preferential activity of some derivatives on certain cerebral areas (mesencephalon or striatum). |
1991-10-28 |
2023-08-11 |
mouse |
| J P Bolam, C M Francis, Z Henderso. Cholinergic input to dopaminergic neurons in the substantia nigra: a double immunocytochemical study. Neuroscience. vol 41. issue 2-3. 1991-09-13. PMID:1678502. |
sections of perfusion-fixed mesencephalon were incubated first to reveal choline acetyltransferase immunoreactivity to label the cholinergic terminals and then tyrosine hydroxylase immunoreactivity to label the dopaminergic neurons. |
1991-09-13 |
2023-08-11 |
rat |
| M Corio, J Peute, H W Steinbusc. Distribution of serotonin- and dopamine-immunoreactivity in the brain of the teleost Clarias gariepinus. Journal of chemical neuroanatomy. vol 4. issue 2. 1991-08-02. PMID:2059346. |
in the midbrain of clarias gariepinus, no dopaminergic homologue of the substantia nigra was observed. |
1991-08-02 |
2023-08-11 |
Not clear |
| T J Mahalik, G H Clayto. Specific outgrowth from neurons of ventral mesencephalic grafts to the catecholamine-depleted striatum of adult hosts. Experimental neurology. vol 113. issue 1. 1991-07-12. PMID:1710572. |
grafts of fetal ventral mesencephalon including substantia nigra have been used to correct some motor deficits produced by unilateral destruction of the dopaminergic nigrostriatal pathway in rats. |
1991-07-12 |
2023-08-11 |
rat |
| T Maeda, Y Kojima, R Arai, M Fujimiya, H Kimura, K Kitahama, M Geffar. Monoaminergic interaction in the central nervous system: a morphological analysis in the locus coeruleus of the rat. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 98. issue 1. 1991-06-13. PMID:1673910. |
there are adrenergic and noradrenergic neurons originating in the medulla oblongata, dopaminergic from the hypothalamus, serotonergic from the mesencephalon and also intrinsic noradrenergic neurons in the locus coeruleus complex. |
1991-06-13 |
2023-08-11 |
rat |
| K Ostergaard, J P Schou, B H Gähwiler, J Zimme. Tyrosine hydroxylase immunoreactive neurons in organotypic slice cultures of the rat striatum and neocortex. Experimental brain research. vol 83. issue 2. 1991-05-31. PMID:1673660. |
in order to examine whether innervation by dopaminergic fibers would affect the expression of th-i neurons in the striatal slice cultures, co-cultures of ventral mesencephalon (vm) and striatum were prepared, but the ingrowth of th-i fibers from the vm did not alter the expression of th immunoreactivity by a subpopulation of striatal neurons. |
1991-05-31 |
2023-08-11 |
rat |
| R F Seegal, B Bush, K O Brosc. Sub-chronic exposure of the adult rat to Aroclor 1254 yields regionally-specific changes in central dopaminergic function. Neurotoxicology. vol 12. issue 1. 1991-05-10. PMID:2014069. |
the susceptibility of the striatum and lateral olfactory tract to insult by pcbs may be due to their innervation by midbrain dopaminergic neurons which have been shown to be particularly sensitive to insult from environmental, infectious and pharmacologic agents. |
1991-05-10 |
2023-08-11 |
rat |
| M J Staal, R I Hogen Esch, R Tomasini, R Kraayenbrink, I P Kema, R M Buijs, K G Go, F Zuiderveen, C H Buy. Qualitative and quantitative examination of rat and human fetal dopaminergic grafts. Stereotactic and functional neurosurgery. vol 54-55. 1991-04-26. PMID:2080344. |
moreover, fetal rat ventral mesencephalon tissue was cultured, and neural dopaminergic cells were observed in cell culture in 4 (11%) out of 36 ventral mesencephalon specimens derived from 15- to 21-day-old rat fetuses. |
1991-04-26 |
2023-08-11 |
human |
| B F Driscoll, M J Law, A M Cran. Cell damage associated with changing the medium of mesencephalic cultures in serum-free medium is mediated via N-methyl-D-aspartate receptors. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:1672142. |
dopaminergic neurons from embryonic rat mesencephalon were grown in simple serum-free media. |
1991-04-15 |
2023-08-11 |
rat |
| K Ostergaard, J P Schou, J Zimme. Rat ventral mesencephalon grown as organotypic slice cultures and co-cultured with striatum, hippocampus, and cerebellum. Experimental brain research. vol 82. issue 3. 1991-04-09. PMID:1981356. |
tissue slices of rat ventral mesencephalon (vm), striatum, hippocampus and cerebellum were prepared from late fetal (e21) to 7 day old (p7) rats and cultured for 3 to 60 days by the roller tube technique before they were stained immunocytochemically for tyrosine hydroxylase (th), a marker of dopaminergic (da) neurons and fibres. |
1991-04-09 |
2023-08-11 |
rat |
| G L Bernardini, S G Speciale, D C Germa. Increased midbrain dopaminergic cell activity following 2'CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study. Brain research. vol 527. issue 1. 1991-03-19. PMID:1980838. |
increased midbrain dopaminergic cell activity following 2'ch3-mptp-induced dopaminergic cell loss: an in vitro electrophysiological study. |
1991-03-19 |
2023-08-11 |
mouse |
| G L Bernardini, S G Speciale, D C Germa. Increased midbrain dopaminergic cell activity following 2'CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study. Brain research. vol 527. issue 1. 1991-03-19. PMID:1980838. |
several days after the administration of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'ch3-mptp) to the balb/cj mouse there is a loss of midbrain dopaminergic neurons, a reduction of forebrain dopamine (da) content, and an elevation in forebrain da turnover. |
1991-03-19 |
2023-08-11 |
mouse |
| G L Bernardini, S G Speciale, D C Germa. Increased midbrain dopaminergic cell activity following 2'CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study. Brain research. vol 527. issue 1. 1991-03-19. PMID:1980838. |
in vitro extracellular single unit recordings were made from midbrain dopaminergic neurons in the substantia nigra pars compacta (nucleus a9) and ventral tegmental area (nucleus a10) of balb/cj mice. |
1991-03-19 |
2023-08-11 |
mouse |
| U Di Porzio, A Zuddas, D B Cosenza-Murphy, J L Barke. Early appearance of tyrosine hydroxylase immunoreactive cells in the mesencephalon of mouse embryos. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 5. 1991-03-08. PMID:1980787. |
after 13 days of gestation two separate catecholaminergic groups could be visualized, although many th positive cells with long neurites (putative dopaminergic neurons) could still be seen at the edges of the ventricle, and appeared to be moving towards the ventral mesencephalon. |
1991-03-08 |
2023-08-11 |
mouse |