| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Bonci, P Grillner, N B Mercuri, G Bernard. L-Type calcium channels mediate a slow excitatory synaptic transmission in rat midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 17. 1998-09-09. PMID:9712641. |
taken together, these results indicate that under certain patterns of synaptic activity, l-type ca2+ channels regulate the synaptic release of excitatory amino acids on the dopaminergic neurons of the ventral mesencephalon. |
1998-09-09 |
2023-08-12 |
rat |
| T J Counihan, J B Penne. Regional dopamine transporter gene expression in the substantia nigra from control and Parkinson's disease brains. Journal of neurology, neurosurgery, and psychiatry. vol 65. issue 2. 1998-08-20. PMID:9703165. |
to test the hypothesis that differential regional dopamine transporter (dat) gene expression may underlie the selective vulnerability of certain nigral dopaminergic neurons in parkinson's disease, dat mrna expression was examined in neuronal subpopulations of human postmortem ventral mesencephalon from patients with parkinson's disease and controls. |
1998-08-20 |
2023-08-12 |
human |
| L R Lucas, P Pompei, J Ono, B S McEwe. Effects of adrenal steroids on basal ganglia neuropeptide mRNA and tyrosine hydroxylase radioimmunoreactive levels in the adrenalectomized rat. Journal of neurochemistry. vol 71. issue 2. 1998-08-19. PMID:9681476. |
there were no significant treatment effects on indirect markers of midbrain dopaminergic activity, i.e., cck mrna and th-ric. |
1998-08-19 |
2023-08-12 |
rat |
| J Sautter, M Meyer, C Spenger, R W Seiler, H R Widme. Effects of combined BDNF and GDNF treatment on cultured dopaminergic midbrain neurons. Neuroreport. vol 9. issue 6. 1998-08-13. PMID:9601674. |
effects of combined bdnf and gdnf treatment on cultured dopaminergic midbrain neurons. |
1998-08-13 |
2023-08-12 |
rat |
| A Ho, M Blu. Induction of interleukin-1 associated with compensatory dopaminergic sprouting in the denervated striatum of young mice: model of aging and neurodegenerative disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 15. 1998-08-07. PMID:9671653. |
young mice challenged with the neurotoxin 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (mptp), which selectively destroys the substantia nigra dopaminergic neurons in the midbrain, exhibit spontaneous recovery of dopaminergic nerve terminals. |
1998-08-07 |
2023-08-12 |
mouse |
| M Ernst, A J Zametkin, J A Matochik, P H Jons, R M Cohe. DOPA decarboxylase activity in attention deficit hyperactivity disorder adults. A [fluorine-18]fluorodopa positron emission tomographic study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 15. 1998-08-07. PMID:9671677. |
on the basis of previous neuroimaging findings in adhd showing discrepant findings in adults and adolescents and on evidence for midbrain dopaminergic defect in adolescents, we hypothesize that the prefrontal dopaminergic abnormality in adhd adults is secondary and results from an interaction of the primary subcortical dopaminergic deficit with processes of neural maturation and neural adaptation. |
1998-08-07 |
2023-08-12 |
Not clear |
| Z U Khan, L Mrzljak, A Gutierrez, A de la Calle, P S Goldman-Raki. Prominence of the dopamine D2 short isoform in dopaminergic pathways. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 13. 1998-08-06. PMID:9636219. |
the d2 short predominates in the cell bodies and projection axons of the dopaminergic cell groups of the mesencephalon and hypothalamus, whereas the d2 long is more strongly expressed by neurons in the striatum and nucleus accumbens, structures targeted by dopaminergic fibers. |
1998-08-06 |
2023-08-12 |
Not clear |
| K Ohyama, H Kawano, H Asou, T Fukuda, A Oohira, K Uyemura, K Kawamur. Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice. Brain research. Developmental brain research. vol 107. issue 2. 1998-07-13. PMID:9593903. |
mesencephalic dopaminergic (da) neurons of mice are generated from embryonic day 10 to 12 (e10-12) in the ventricular zone of the mesencephalon. |
1998-07-13 |
2023-08-12 |
mouse |
| N Vidal, L Björklund, I Strömber. Morphological and functional evidence for enhanced growth and potassium-evoked dopamine release in striatal grafts innervated with a patchy growth pattern. An in oculo nigrostriatal cograft study. Cell transplantation. vol 7. issue 2. 1998-07-10. PMID:9588592. |
it has been suggested that when fetal dopaminergic neurons, obtained from the ventral mesencephalon (vm), are grafted adjacent to mature striatal tissue, only the diffuse growth is induced. |
1998-07-10 |
2023-08-12 |
Not clear |
| D Sulzer, M P Joyce, L Lin, D Geldwert, S N Haber, T Hattori, S Raypor. Dopamine neurons make glutamatergic synapses in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 12. 1998-07-08. PMID:9614234. |
several lines of evidence have suggested that the ventral midbrain dopamine neurons that give rise to the major cns dopaminergic projections may also be glutamatergic. |
1998-07-08 |
2023-08-12 |
rat |
| W Ye, K Shimamura, J L Rubenstein, M A Hynes, A Rosentha. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell. vol 93. issue 5. 1998-07-06. PMID:9630220. |
we provide evidence that intersections of shh, which is expressed along the ventral neural tube, and fgf8, which is locally produced at the mid/hindbrain boundary and in the rostral forebrain, create induction sites for dopaminergic neurons in the midbrain and forebrain. |
1998-07-06 |
2023-08-12 |
Not clear |
| B A Horger, M C Nishimura, M P Armanini, L C Wang, K T Poulsen, C Rosenblad, D Kirik, B Moffat, L Simmons, E Johnson, J Milbrandt, A Rosenthal, A Bjorklund, R A Vandlen, M A Hynes, H S Phillip. Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 13. 1998-07-02. PMID:9634558. |
neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. |
1998-07-02 |
2023-08-12 |
Not clear |
| B A Horger, M C Nishimura, M P Armanini, L C Wang, K T Poulsen, C Rosenblad, D Kirik, B Moffat, L Simmons, E Johnson, J Milbrandt, A Rosenthal, A Bjorklund, R A Vandlen, M A Hynes, H S Phillip. Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 13. 1998-07-02. PMID:9634558. |
glial cell line-derived neurotrophic factor (gdnf) exhibits potent effects on survival and function of midbrain dopaminergic (da) neurons in a variety of models. |
1998-07-02 |
2023-08-12 |
Not clear |
| A Lee, A E Wissekerke, D L Rosin, K R Lync. Localization of alpha2C-adrenergic receptor immunoreactivity in catecholaminergic neurons in the rat central nervous system. Neuroscience. vol 84. issue 4. 1998-06-23. PMID:9578397. |
in the midbrain, alpha2c-adrenergic receptor immunoreactivity was detected in most tyrosine hydroxylase-immunoreactive cells in dopaminergic regions (63% in the retrorubral field, 77-83% in substantia nigra, 67% in ventral tegmental area). |
1998-06-23 |
2023-08-12 |
rat |
| S G Speciale, C L Liang, P K Sonsalla, R H Edwards, D C Germa. The neurotoxin 1-methyl-4-phenylpyridinium is sequestered within neurons that contain the vesicular monoamine transporter. Neuroscience. vol 84. issue 4. 1998-06-23. PMID:9578404. |
there was a positive relationship between the density of [3h]1-methyl-4-phenylpyridinium label and the density of vesicular monoamine transporter immunoreactivity: the highest densities of both were found in the locus coeruleus and lowest densities in the midbrain dopaminergic neurons. |
1998-06-23 |
2023-08-12 |
mouse |
| S G Speciale, C L Liang, P K Sonsalla, R H Edwards, D C Germa. The neurotoxin 1-methyl-4-phenylpyridinium is sequestered within neurons that contain the vesicular monoamine transporter. Neuroscience. vol 84. issue 4. 1998-06-23. PMID:9578404. |
since nuclei with intense labelling are not damaged by doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine that are toxic to midbrain dopaminergic neurons, these data are consistent with the hypothesis that sequestration of 1-methyl-4-phenylpyridinium within monoaminergic synaptic vesicles can protect the neurons from degeneration caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. |
1998-06-23 |
2023-08-12 |
mouse |
| S M Nicola, R C Malenk. Modulation of synaptic transmission by dopamine and norepinephrine in ventral but not dorsal striatum. Journal of neurophysiology. vol 79. issue 4. 1998-05-27. PMID:9535946. |
in particular, dopaminergic afferents from the midbrain appear to be essential for the normal functioning of both nuclei. |
1998-05-27 |
2023-08-12 |
Not clear |
| B A Bennett, C K Hollingsworth, R S Martin, J J Har. Methamphetamine-induced alterations in dopamine transporter function. Brain research. vol 782. issue 1-2. 1998-05-14. PMID:9519266. |
fetal midbrain cultures were exposed to meth (1, 10 microm) for 5 days and dopaminergic function examined 1 or 7 days after drug removal. |
1998-05-14 |
2023-08-12 |
rat |
| J Engel. Changing responsiveness of developing midbrain dopaminergic neurons for extracellular growth factors. Journal of neuroscience research. vol 51. issue 4. 1998-05-11. PMID:9514204. |
changing responsiveness of developing midbrain dopaminergic neurons for extracellular growth factors. |
1998-05-11 |
2023-08-12 |
rat |
| J Engel. Changing responsiveness of developing midbrain dopaminergic neurons for extracellular growth factors. Journal of neuroscience research. vol 51. issue 4. 1998-05-11. PMID:9514204. |
to further characterize the functional role of these multiple growth factor influences in dopaminergic cell development, various purified growth factors as well as mesencephalic glial-conditioned medium (cm) were screened for effects on dopaminergic cell survival and glial numbers in serum-free low density cultures of the dissociated embryonic day (e) 15 and e17 rat mesencephalon. |
1998-05-11 |
2023-08-12 |
rat |