| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesca L'episcopo, Maria F Serapide, Cataldo Tirolo, Nunzio Testa, Salvatore Caniglia, Maria C Morale, Stefano Pluchino, Bianca Marchett. A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection. Molecular neurodegeneration. vol 6. 2011-11-10. PMID:21752258. |
dopamine-synthesizing (dopaminergic, da) neurons in the ventral midbrain (vm) constitute a pivotal neuronal population controlling motor behaviors, cognitive and affective brain functions, which generation critically relies on the activation of wingless-type mmtv integration site (wnt)/β-catenin pathway in their progenitors. |
2011-11-10 |
2023-08-12 |
mouse |
| Alessandra Bonito-Oliva, Michael Feyder, Gilberto Fison. Deciphering the Actions of Antiparkinsonian and Antipsychotic Drugs on cAMP/DARPP-32 Signaling. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21808606. |
msns receive a large glutamatergic innervation from cortex, thalamus, and limbic structures, and are controlled by dopaminergic projections originating in the midbrain. |
2011-11-10 |
2023-08-12 |
Not clear |
| Pierre F Durieux, Serge N Schiffmann, Alban de Kerchove d'Exaerd. Targeting neuronal populations of the striatum. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21811438. |
the gaba medium-sized spiny neurons (msns, about 95% of striatal neurons), which are targets of the cerebral cortex and the midbrain dopaminergic neurons, form two pathways. |
2011-11-10 |
2023-08-12 |
Not clear |
| Michael Fiske, Stephanie Valtierra, Keith Solvang, Michael Zorniak, Michael White, Sara Herrera, Alina Konnikova, Rebecca Brezinsky, Shubhik Debburma. Contribution of Alanine-76 and Serine Phosphorylation in α-Synuclein Membrane Association and Aggregation in Yeasts. Parkinson's disease. vol 2011. 2011-11-10. PMID:21826257. |
in parkinson's disease (pd), misfolded and aggregated α-synuclein protein accumulates in degenerating midbrain dopaminergic neurons. |
2011-11-10 |
2023-08-12 |
Not clear |
| Mario Gustavo Murer, Rosario Moratall. Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21886608. |
parkinson's disease is a common neurodegenerative disorder caused by the degeneration of midbrain substantia nigra dopaminergic neurons that project to the striatum. |
2011-11-10 |
2023-08-12 |
Not clear |
| Christopher J Burke, Philippe N Toble. Coding of reward probability and risk by single neurons in animals. Frontiers in neuroscience. vol 5. 2011-11-10. PMID:22013410. |
reward variance is represented in orbitofrontal and posterior cingulate cortex and through a sustained response of dopaminergic midbrain neurons. |
2011-11-10 |
2023-08-12 |
rat |
| Timothy J Petros, Jennifer A Tyson, Stewart A Anderso. Pluripotent stem cells for the study of CNS development. Frontiers in molecular neuroscience. vol 4. 2011-11-10. PMID:22016722. |
additionally, we highlight the derivation of several thoroughly characterized neural subtypes; spinal motoneurons, midbrain dopaminergic neurons and cortical neurons. |
2011-11-10 |
2023-08-12 |
human |
| Andrii Domanskyi, Christin Geissler, Ilya A Vinnikov, Heike Alter, Andreas Schober, Miriam A Vogt, Peter Gass, Rosanna Parlato, Günther Schüt. Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 25. issue 9. 2011-11-09. PMID:21593433. |
parkinson's disease (pd) is a progressive age-related movement disorder that results primarily from the selective loss of midbrain dopaminergic (da) neurons. |
2011-11-09 |
2023-08-12 |
mouse |
| Vishnu P Murty, Fabio Sambataro, Eugenia Radulescu, Mario Altamura, Jennifer Iudicello, Bradley Zoltick, Daniel R Weinberger, Terry E Goldberg, Venkata S Matta. Selective updating of working memory content modulates meso-cortico-striatal activity. NeuroImage. vol 57. issue 3. 2011-11-09. PMID:21596142. |
accumulating evidence from non-human primates and computational modeling suggests that dopaminergic signals arising from the midbrain (substantia nigra/ventral tegmental area) mediate striatal gating of the prefrontal cortex during the selective updating of working memory. |
2011-11-09 |
2023-08-12 |
human |
| Paul W Glimche. Understanding dopamine and reinforcement learning: the dopamine reward prediction error hypothesis. Proceedings of the National Academy of Sciences of the United States of America. vol 108 Suppl 3. 2011-11-03. PMID:21389268. |
a number of recent advances have been achieved in the study of midbrain dopaminergic neurons. |
2011-11-03 |
2023-08-12 |
human |
| Carol H Yan, Martin Levesque, Suzanne Claxton, Randy L Johnson, Siew-Lan An. Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 35. 2011-10-21. PMID:21880902. |
lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. |
2011-10-21 |
2023-08-12 |
mouse |
| Carol H Yan, Martin Levesque, Suzanne Claxton, Randy L Johnson, Siew-Lan An. Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 35. 2011-10-21. PMID:21880902. |
lim homeodomain transcription factors, lmx1a and lmx1b, are required for the development of midbrain dopaminergic (mda) neurons. |
2011-10-21 |
2023-08-12 |
mouse |
| Damian Refojo, Martin Schweizer, Claudia Kuehne, Stefanie Ehrenberg, Christoph Thoeringer, Annette M Vogl, Nina Dedic, Marion Schumacher, Gregor von Wolff, Charilaos Avrabos, Chadi Touma, David Engblom, Günther Schütz, Klaus-Armin Nave, Matthias Eder, Carsten T Wotjak, Inge Sillaber, Florian Holsboer, Wolfgang Wurst, Jan M Deussin. Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science (New York, N.Y.). vol 333. issue 6051. 2011-10-18. PMID:21885734. |
using neurochemical and genetic tools, we determined that crhr1 is expressed in forebrain glutamatergic and γ-aminobutyric acid-containing (gabaergic) neurons as well as in midbrain dopaminergic neurons. |
2011-10-18 |
2023-08-12 |
Not clear |
| Damian Refojo, Martin Schweizer, Claudia Kuehne, Stefanie Ehrenberg, Christoph Thoeringer, Annette M Vogl, Nina Dedic, Marion Schumacher, Gregor von Wolff, Charilaos Avrabos, Chadi Touma, David Engblom, Günther Schütz, Klaus-Armin Nave, Matthias Eder, Carsten T Wotjak, Inge Sillaber, Florian Holsboer, Wolfgang Wurst, Jan M Deussin. Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science (New York, N.Y.). vol 333. issue 6051. 2011-10-18. PMID:21885734. |
selective deletion of crhr1 in midbrain dopaminergic neurons increases anxiety-like behavior and reduces dopamine release in the prefrontal cortex. |
2011-10-18 |
2023-08-12 |
Not clear |
| Y Yu, T We. Generation of dopaminergic neurons by fusion of neural stem cells and midbrain neurons. Cellular and molecular biology (Noisy-le-Grand, France). vol 57 Suppl. 2011-10-17. PMID:21791171. |
generation of dopaminergic neurons by fusion of neural stem cells and midbrain neurons. |
2011-10-17 |
2023-08-12 |
Not clear |
| Y Yu, T We. Generation of dopaminergic neurons by fusion of neural stem cells and midbrain neurons. Cellular and molecular biology (Noisy-le-Grand, France). vol 57 Suppl. 2011-10-17. PMID:21791171. |
nscs were fused with midbrain neurons, resulting in hybrid cells that express an antigen pattern characteristic of dopaminergic neurons. |
2011-10-17 |
2023-08-12 |
Not clear |
| Kazuhiro Kurokawa, Koji Mizuno, Emi Kiyokage, Masahiro Shibasaki, Kazunori Toida, Seitaro Ohkum. Dopamine D1 receptor signaling system regulates ryanodine receptor expression after intermittent exposure to methamphetamine in primary cultures of midbrain and cerebral cortical neurons. Journal of neurochemistry. vol 118. issue 5. 2011-10-14. PMID:21707617. |
this study investigate regulatory mechanisms of ryr expression by dopaminergic system using the midbrain and cerebral cortical neurons in primary culture intermittently exposed to meth and dopamine receptor (dr) agonists (1 h/day, for 3 days). |
2011-10-14 |
2023-08-12 |
mouse |
| Zhinian Lei, Yu Jiang, Tao Li, Jianbao Zhu, Shuilin Zen. Signaling of glial cell line-derived neurotrophic factor and its receptor GFRα1 induce Nurr1 and Pitx3 to promote survival of grafted midbrain-derived neural stem cells in a rat model of Parkinson disease. Journal of neuropathology and experimental neurology. vol 70. issue 9. 2011-10-14. PMID:21865882. |
glial cell line-derived neurotrophic factor (gdnf) and its receptor gfrα1 have been implicated in the survival of ventral midbrain dopaminergic (da) neurons, but the molecular mechanisms bywhich gdnf generates da neurons in grafted midbrain-derived neural stem cells (mnscs) are not understood. |
2011-10-14 |
2023-08-12 |
rat |
| K B Reynolds, L MacGillivray, M Zettler, P I Rosebush, M F Mazure. Role of the dopamine transporter in mediating the neuroleptic-induced reduction of tyrosine hydroxylase-immunoreactive midbrain neurons. Brain research. vol 1394. 2011-10-11. PMID:21396352. |
we have previously reported a long-term downregulation of midbrain dopaminergic neurons following treatment with neuroleptic medications. |
2011-10-11 |
2023-08-12 |
rat |
| K B Reynolds, L MacGillivray, M Zettler, P I Rosebush, M F Mazure. Role of the dopamine transporter in mediating the neuroleptic-induced reduction of tyrosine hydroxylase-immunoreactive midbrain neurons. Brain research. vol 1394. 2011-10-11. PMID:21396352. |
these results indicate a role for the active dopamine transporter in mediating the suppression of th expression in midbrain dopaminergic neurons by antipsychotic drugs. |
2011-10-11 |
2023-08-12 |
rat |