| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Allen Hill, Hiram Cantú, Julie N Côté, Julie Nante. Reaching and stepping respond differently to medication and cueing in Parkinson's disease. Scientific reports. vol 14. issue 1. 2024-10-18. PMID:39424838. |
the basal ganglia contribute to internal timekeeping, and dopaminergic medication has been observed to moderate timing deficits associated with parkinson's disease (pd) during single joint movements. |
2024-10-18 |
2024-10-21 |
Not clear |
| Chelsea M Haakenson, Jacques Balthazart, Jonathan W VanRyzin, Ashley E Marquardt, Sydney E Ashton, Margaret M McCarthy, Gregory F Bal. Neurochemical Characterization of Dopaminoceptive Cells in Song Control Nuclei of Canaries and Their Activation During Song Production: A Multiplex Fluorescent In Situ Hybridization Study. The Journal of comparative neurology. vol 532. issue 10. 2024-10-10. PMID:39387367. |
highly sensitive in situ hybridization procedures (rnascope) were used to quantify the expression of three dopamine receptors (drd1, drd2, and drd3) in two song control nuclei (hvc and the area x of the basal ganglia) that are known to receive dopaminergic inputs and in the periaqueductal gray (pag) of male and female canaries. |
2024-10-10 |
2024-10-16 |
Not clear |
| Hong-Yuan Chu, Liqiang Chen, Hiba Douja Chehad. Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation. Research square. 2024-09-16. PMID:39281856. |
while cortical function is known to be suppressed by abnormal basal ganglia output following dopaminergic degeneration, it remains to be determined how the deposition of lewy pathology disrupts cortical circuit integrity and function. |
2024-09-16 |
2024-09-19 |
mouse |
| Elham Baradari, Ozgur B Aka. Molecular Communication-Based Intelligent Dopamine Rate Modulator for Parkinson's Disease Treatment. IEEE transactions on nanobioscience. vol PP. 2024-09-13. PMID:39264786. |
parkinson's disease (pd) is a progressive neurodegenerative disease, and it is caused by the loss of dopaminergic neurons in the basal ganglia (bg). |
2024-09-13 |
2024-09-15 |
Not clear |
| Sarah Chevalier, Mélina Decourt, Maureen Francheteau, François Nicol, Anaïs Balbous, Pierre-Olivier Fernagut, Marianne Benoit-Maran. Alpha-synuclein-induced nigrostriatal degeneration and pramipexole treatment disrupt frontostriatal plasticity. NPJ Parkinson's disease. vol 10. issue 1. 2024-09-09. PMID:39251645. |
this study demonstrates that nigral dopaminergic loss and ppx both contribute to alter frontostriatal transmission, precluding adequate information processing in associative basal ganglia loops as a gateway for the development of non-motor symptoms or non-motor side effects of drt. |
2024-09-09 |
2024-09-13 |
human |
| María Fernanda Urmeneta-Ortíz, Aldo Rafael Tejeda-Martínez, Orfil González-Reynoso, Mario Eduardo Flores-Sot. Potential Neuroprotective Effect of the Endocannabinoid System on Parkinson's Disease. Parkinson's disease. vol 2024. 2024-08-06. PMID:39104613. |
the endocannabinoid system (ecs), highly expressed in the basal ganglia (bg) circuit, undergoes alterations in response to dopaminergic depletion, potentially contributing to motor symptoms and the etiopathogenesis of pd. |
2024-08-06 |
2024-08-08 |
Not clear |
| C Vigneswaran, Sandeep Sathyanandan Nair, V Srinivasa Chakravarth. A Basal Ganglia model for understanding working memory functions in healthy and Parkinson's conditions. Cognitive neurodynamics. vol 18. issue 4. 2024-08-06. PMID:39104688. |
the basal ganglia (bg) and prefrontal cortex are two important parts of the brain that are involved in wm functions, and both structures receive projections from dopaminergic nuclei. |
2024-08-06 |
2024-08-08 |
human |
| Liqiang Chen, Hiba Douja Chehade, Hong-Yuan Ch. Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation. bioRxiv : the preprint server for biology. 2024-08-02. PMID:39091827. |
while cortical function is known to be suppressed by abnormal basal ganglia output following dopaminergic degeneration, it remains to be determined how the deposition of lewy pathology disrupts cortical circuit integrity and function. |
2024-08-02 |
2024-08-05 |
mouse |
| Sandeep Sathyanandan Nair, Srinivasa Chakravarth. A Computational Model of Deep Brain Stimulation for Parkinson's Disease Tremor and Bradykinesia. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928620. |
the loss of dopaminergic neurons in the substantia nigra pars compacta (snc) leads to an array of dysfunctions in the functioning of the basal ganglia (bg) circuitry that manifests into pd. |
2024-06-27 |
2024-06-29 |
Not clear |
| Benedetta Gambosi, Francesco Jamal Sheiban, Marco Biasizzo, Alberto Antonietti, Egidio D'angelo, Alberto Mazzoni, Alessandra Pedrocch. A Model with Dopamine Depletion in Basal Ganglia and Cerebellum Predicts Changes in Thalamocortical Beta Oscillations. International journal of neural systems. 2024-06-17. PMID:38886870. |
the discovery that those motor symptoms result from the death of dopaminergic cells in the substantia nigra led to focus most of parkinsonism research on the basal ganglia (bg). |
2024-06-17 |
2024-06-21 |
Not clear |
| Érica de Moraes Santos Corrêa, Gustavo Christofoletti, Albert Schiaveto de Souz. Effects of Intracerebral Aminophylline Dosing on Catalepsy and Gait in an Animal Model of Parkinson's Disease. International journal of molecular sciences. vol 25. issue 10. 2024-05-25. PMID:38791229. |
parkinson's disease (pd) is a progressive disorder characterized by the apoptosis of dopaminergic neurons in the basal ganglia. |
2024-05-25 |
2024-05-27 |
Not clear |
| Yash Wardhan, Sukriti Vishwas, Arumugam Porselvi, Sachin Kumar Singh, Violina Kakot. Exploring the complex interplay between Parkinson's Disease and BAG proteins. Behavioural brain research. 2024-05-20. PMID:38768687. |
parkinsons disease (pd) is a chronic fast growing neurodegenerative disorder of central nervous system (cns) characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) and formation of lewy bodies (lbs) which causes dopamine deficiency within basal ganglia leading to motor and non-motor manifestation. |
2024-05-20 |
2024-05-27 |
Not clear |
| Andrea Juárez Tello, Cornelis Immanuel van der Zouwen, Léonie Dejas, Juan Duque-Yate, Joël Boutin, Katherine Medina-Ortiz, Jacinthlyn Sylvia Suresh, Jordan Swiegers, Philippe Sarret, Dimitri Ryczk. Dopamine-sensitive neurons in the mesencephalic locomotor region control locomotion initiation, stop, and turns. Cell reports. vol 43. issue 5. 2024-05-09. PMID:38722743. |
the locomotor role of dopaminergic neurons is traditionally attributed to their ascending projections to the basal ganglia, which project to the mesencephalic locomotor region (mlr). |
2024-05-09 |
2024-05-27 |
Not clear |
| Suraj Cherian, Gabriel Simms, Liqiang Chen, Hong-Yuan Ch. Loss of Midbrain Dopamine Neurons Does Not Alter GABAergic Inhibition Mediated by Parvalbumin-Expressing Interneurons in Mouse Primary Motor Cortex. eNeuro. 2024-04-24. PMID:38658137. |
specifically, dopaminergic degeneration and basal ganglia dysfunction entrain m1 neurons into the abnormally synchronized bursting pattern of activity throughout the cortico-basal ganglia-thalamocortical network. |
2024-04-24 |
2024-04-28 |
mouse |
| Maya Molinari, Ori J Lieberman, David Sulzer, Emanuela Santini, Anders Borgkvis. 5-HT1B receptors mediate dopaminergic inhibition of vesicular fusion and GABA release from striatonigral synapses. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559006. |
the substantia nigra pars reticulata (snr), a crucial basal ganglia output nucleus, contains a dense expression of dopamine d1 receptors (d1rs), along with dendrites belonging to dopaminergic neurons of substantia nigra pars compacta. |
2024-04-01 |
2024-04-04 |
Not clear |
| Motoko Watanabe, Chihiro Takao, Chizuko Maeda, Gayatri Nayanar, Risa Tominaga, Yasuyuki Kimura, Trang Thi Huyen Tu, Takahiko Nagamine, Akira Toyofuk. The effective perospirone augmentation with clonazepam for treatment-resistant burning mouth syndrome: A case report. Neuropsychopharmacology reports. 2024-03-19. PMID:38500267. |
the reported cases suggested that multiple approaches targeting the dopaminergic circuit in basal ganglia involving the serotoninergic and gaba systems, through the administration of perospirone with clonazepam is an effective adjunctive treatment for the remaining uncomfortable sensations in patients with bms. |
2024-03-19 |
2024-03-21 |
Not clear |
| Liancai Mu, Jingming Chen, Jing Li, Themba Nyirenda, Karen Wheeler Hegland, Thomas G Beac. Mechanisms of Swallowing, Speech and Voice Disorders in Parkinson's Disease: Literature Review with Our First Evidence for the Periperal Nervous System Involvement. Dysphagia. 2024-03-18. PMID:38498201. |
pd was long considered to be a central nervous system disorder caused by the death of dopaminergic neurons in the basal ganglia. |
2024-03-18 |
2024-03-21 |
Not clear |
| Ana Araújo, Isabel Catarina Duarte, Teresa Sousa, Joana Oliveira, Ana Telma Pereira, António Macedo, Miguel Castelo-Branc. Neural inhibition as implemented by an actor-critic model involves the human dorsal striatum and ventral tegmental area. Scientific reports. vol 14. issue 1. 2024-03-17. PMID:38493169. |
rodent and computational studies show that midbrain regions play crucial roles during errors by sending dopaminergic learning signals to the basal ganglia for behavioural adjustment. |
2024-03-17 |
2024-03-19 |
human |
| Jean F Liénard, Lise Aubin, Ignasi Cos, Benoît Girar. Estimation of the transmission delays in the basal ganglia of the macaque monkey and subsequent predictions about oscillatory activity under dopamine depletion. The European journal of neuroscience. 2024-02-28. PMID:38414108. |
we then integrate these delays in a model of the primate basal ganglia that does not rely on direct and indirect pathways' segregation and show that extrastriatal dopaminergic depletion in the external part of the globus pallidus and in the subthalamic nucleus is sufficient to generate β-band oscillations (in the high part, 20-35 hz, of the band). |
2024-02-28 |
2024-03-01 |
monkey |
| Aleksa Cuk, Timea Bezdan, Luka Jovanovic, Milos Antonijevic, Milos Stankovic, Vladimir Simic, Miodrag Zivkovic, Nebojsa Bacani. Tuning attention based long-short term memory neural networks for Parkinson's disease detection using modified metaheuristics. Scientific reports. vol 14. issue 1. 2024-02-21. PMID:38383690. |
parkinson's disease (pd) is a progressively debilitating neurodegenerative disorder that primarily affects the dopaminergic system in the basal ganglia, impacting millions of individuals globally. |
2024-02-21 |
2024-02-24 |
Not clear |