| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sandeep Sathyanandan Nair, Srinivasa Chakravarth. A Computational Model of Deep Brain Stimulation for Parkinson's Disease Tremor and Bradykinesia. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928620. |
the loss of dopaminergic neurons in the substantia nigra pars compacta (snc) leads to an array of dysfunctions in the functioning of the basal ganglia (bg) circuitry that manifests into pd. |
2024-06-27 |
2024-06-29 |
Not clear |
| Benedetta Gambosi, Francesco Jamal Sheiban, Marco Biasizzo, Alberto Antonietti, Egidio D'angelo, Alberto Mazzoni, Alessandra Pedrocch. A Model with Dopamine Depletion in Basal Ganglia and Cerebellum Predicts Changes in Thalamocortical Beta Oscillations. International journal of neural systems. 2024-06-17. PMID:38886870. |
the discovery that those motor symptoms result from the death of dopaminergic cells in the substantia nigra led to focus most of parkinsonism research on the basal ganglia (bg). |
2024-06-17 |
2024-06-21 |
Not clear |
| Érica de Moraes Santos Corrêa, Gustavo Christofoletti, Albert Schiaveto de Souz. Effects of Intracerebral Aminophylline Dosing on Catalepsy and Gait in an Animal Model of Parkinson's Disease. International journal of molecular sciences. vol 25. issue 10. 2024-05-25. PMID:38791229. |
parkinson's disease (pd) is a progressive disorder characterized by the apoptosis of dopaminergic neurons in the basal ganglia. |
2024-05-25 |
2024-05-27 |
Not clear |
| Yash Wardhan, Sukriti Vishwas, Arumugam Porselvi, Sachin Kumar Singh, Violina Kakot. Exploring the complex interplay between Parkinson's Disease and BAG proteins. Behavioural brain research. 2024-05-20. PMID:38768687. |
parkinsons disease (pd) is a chronic fast growing neurodegenerative disorder of central nervous system (cns) characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) and formation of lewy bodies (lbs) which causes dopamine deficiency within basal ganglia leading to motor and non-motor manifestation. |
2024-05-20 |
2024-05-27 |
Not clear |
| Andrea Juárez Tello, Cornelis Immanuel van der Zouwen, Léonie Dejas, Juan Duque-Yate, Joël Boutin, Katherine Medina-Ortiz, Jacinthlyn Sylvia Suresh, Jordan Swiegers, Philippe Sarret, Dimitri Ryczk. Dopamine-sensitive neurons in the mesencephalic locomotor region control locomotion initiation, stop, and turns. Cell reports. vol 43. issue 5. 2024-05-09. PMID:38722743. |
the locomotor role of dopaminergic neurons is traditionally attributed to their ascending projections to the basal ganglia, which project to the mesencephalic locomotor region (mlr). |
2024-05-09 |
2024-05-27 |
Not clear |
| Suraj Cherian, Gabriel Simms, Liqiang Chen, Hong-Yuan Ch. Loss of Midbrain Dopamine Neurons Does Not Alter GABAergic Inhibition Mediated by Parvalbumin-Expressing Interneurons in Mouse Primary Motor Cortex. eNeuro. 2024-04-24. PMID:38658137. |
specifically, dopaminergic degeneration and basal ganglia dysfunction entrain m1 neurons into the abnormally synchronized bursting pattern of activity throughout the cortico-basal ganglia-thalamocortical network. |
2024-04-24 |
2024-04-28 |
mouse |
| Maya Molinari, Ori J Lieberman, David Sulzer, Emanuela Santini, Anders Borgkvis. 5-HT1B receptors mediate dopaminergic inhibition of vesicular fusion and GABA release from striatonigral synapses. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559006. |
the substantia nigra pars reticulata (snr), a crucial basal ganglia output nucleus, contains a dense expression of dopamine d1 receptors (d1rs), along with dendrites belonging to dopaminergic neurons of substantia nigra pars compacta. |
2024-04-01 |
2024-04-04 |
Not clear |
| Motoko Watanabe, Chihiro Takao, Chizuko Maeda, Gayatri Nayanar, Risa Tominaga, Yasuyuki Kimura, Trang Thi Huyen Tu, Takahiko Nagamine, Akira Toyofuk. The effective perospirone augmentation with clonazepam for treatment-resistant burning mouth syndrome: A case report. Neuropsychopharmacology reports. 2024-03-19. PMID:38500267. |
the reported cases suggested that multiple approaches targeting the dopaminergic circuit in basal ganglia involving the serotoninergic and gaba systems, through the administration of perospirone with clonazepam is an effective adjunctive treatment for the remaining uncomfortable sensations in patients with bms. |
2024-03-19 |
2024-03-21 |
Not clear |
| Liancai Mu, Jingming Chen, Jing Li, Themba Nyirenda, Karen Wheeler Hegland, Thomas G Beac. Mechanisms of Swallowing, Speech and Voice Disorders in Parkinson's Disease: Literature Review with Our First Evidence for the Periperal Nervous System Involvement. Dysphagia. 2024-03-18. PMID:38498201. |
pd was long considered to be a central nervous system disorder caused by the death of dopaminergic neurons in the basal ganglia. |
2024-03-18 |
2024-03-21 |
Not clear |
| Ana Araújo, Isabel Catarina Duarte, Teresa Sousa, Joana Oliveira, Ana Telma Pereira, António Macedo, Miguel Castelo-Branc. Neural inhibition as implemented by an actor-critic model involves the human dorsal striatum and ventral tegmental area. Scientific reports. vol 14. issue 1. 2024-03-17. PMID:38493169. |
rodent and computational studies show that midbrain regions play crucial roles during errors by sending dopaminergic learning signals to the basal ganglia for behavioural adjustment. |
2024-03-17 |
2024-03-19 |
human |
| Jean F Liénard, Lise Aubin, Ignasi Cos, Benoît Girar. Estimation of the transmission delays in the basal ganglia of the macaque monkey and subsequent predictions about oscillatory activity under dopamine depletion. The European journal of neuroscience. 2024-02-28. PMID:38414108. |
we then integrate these delays in a model of the primate basal ganglia that does not rely on direct and indirect pathways' segregation and show that extrastriatal dopaminergic depletion in the external part of the globus pallidus and in the subthalamic nucleus is sufficient to generate β-band oscillations (in the high part, 20-35 hz, of the band). |
2024-02-28 |
2024-03-01 |
monkey |
| Aleksa Cuk, Timea Bezdan, Luka Jovanovic, Milos Antonijevic, Milos Stankovic, Vladimir Simic, Miodrag Zivkovic, Nebojsa Bacani. Tuning attention based long-short term memory neural networks for Parkinson's disease detection using modified metaheuristics. Scientific reports. vol 14. issue 1. 2024-02-21. PMID:38383690. |
parkinson's disease (pd) is a progressively debilitating neurodegenerative disorder that primarily affects the dopaminergic system in the basal ganglia, impacting millions of individuals globally. |
2024-02-21 |
2024-02-24 |
Not clear |
| Larissa Pereira Dantas da Silva, Erika da Cruz Guedes, Isabel Cristina Oliveira Fernandes, Lucas Aleixo Leal Pedroza, Gustavo José da Silva Pereira, Priscila Guber. Exploring Caenorhabditis elegans as Parkinson's Disease Model: Neurotoxins and Genetic Implications. Neurotoxicity research. vol 42. issue 1. 2024-02-06. PMID:38319410. |
patients with pd have a loss of dopaminergic neurons in the substantia nigra of the basal ganglia, which controls voluntary movements, causing a motor impairment as a result of dopaminergic signaling impairment. |
2024-02-06 |
2024-02-09 |
human |
| Alessia Cavallo, Wolf-Julian Neuman. Dopaminergic reinforcement in the motor system: Implications for Parkinson's disease and deep brain stimulation. The European journal of neuroscience. 2024-01-05. PMID:38178558. |
we outline how the basal ganglia pathways could drive strengthening and weakening of circuit dynamics and discuss the implication of this hypothesis on the understanding of motor signs of parkinson's disease (pd), the most frequent dopaminergic disorder. |
2024-01-05 |
2024-01-07 |
human |
| Narmadhaa Sivagurunathan, Mohamudha Parveen Rahamathulla, Hussein Al-Dossary, Latchoumycandane Calivaratha. Emerging Role of Long Noncoding RNAs in Regulating Inflammasome-Mediated Neurodegeneration in Parkinson's Disease. Molecular neurobiology. 2023-12-17. PMID:38105409. |
the underlying pathophysiology involves the progressive loss of dopaminergic neurons within the substantia nigra pars compacta, leading to dopamine depletion in the basal ganglia circuitry. |
2023-12-17 |
2023-12-21 |
Not clear |
| Zihao Li, Yunong Sun, Lingjun Ding, Jing Yang, Jinrong Huang, Mengnan Cheng, Liang Wu, Zhenkun Zhuang, Cheng Chen, Yunqi Huang, Zhiyong Zhu, Siyuan Jiang, Fubaoqian Huang, Chunqing Wang, Shiping Liu, Longqi Liu, Ying Le. Deciphering the distinct transcriptomic and gene regulatory map in adult macaque basal ganglia cells. GigaScience. vol 12. 2023-12-13. PMID:38091510. |
the degeneration of dopaminergic neurons in the basal ganglia is the primary pathological feature of parkinson's disease. |
2023-12-13 |
2023-12-17 |
monkey |
| Laura Cabral, Finnegan J Calabro, Will Foran, Ashley C Parr, Amar Ojha, Jerod Rasmussen, Rafael Ceschin, Ashok Panigrahy, Beatriz Lun. Multivariate and regional age-related change in basal ganglia iron in neonates. Cerebral cortex (New York, N.Y. : 1991). 2023-12-07. PMID:38059685. |
to assess age-related development, we used a measure of basal ganglia physiology, specifically brain tissue iron, obtained from nt2* signal in resting-state functional magnetic resonance imaging (rsfmri), associated with dopaminergic processing. |
2023-12-07 |
2023-12-10 |
human |
| Rupert D Smit, Biswarup Ghosh, Thomas J Campion, Rachel Stingel, Emily Lavell, Robert Hooper, Xiaoxuan Fan, Jonathan Soboloff, George M Smit. STAT3 protects dopaminergic neurons against degeneration in animal model of Parkinson's disease. Brain research. vol 1824. 2023-12-01. PMID:38030102. |
parkinson's disease (pd) is the most prevalent disorder of the basal ganglia, propagated by the degeneration of axon terminals within the striatum and subsequent loss of dopaminergic neurons in the substantia nigra (sn). |
2023-12-01 |
2023-12-10 |
Not clear |
| Rafael Rivas-Santisteban, Alberto Rico, Ana Muñoz, Ana I Rodriguez, Irene Reyes-Resina, Gemma Navarro, José Luis Labandeira-García, José Luis Lanciego, Rafael Franc. Boolean analysis shows a high proportion of dopamine D Neurobiology of disease. 2023-11-02. PMID:37918757. |
boolean analysis shows a high proportion of dopamine d the antagonistic effect of adenosine on dopaminergic transmission in the basal ganglia indirect motor control pathway is mediated by dopamine d |
2023-11-02 |
2023-11-08 |
Not clear |
| Shenyu Zhai, Qiaoling Cui, DeNard V Simmons, D James Surmeie. Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease. Current opinion in neurobiology. vol 83. 2023-10-22. PMID:37866012. |
distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in parkinson's disease. |
2023-10-22 |
2023-11-08 |
mouse |