| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexey P Bolshakov, Konstantin Gerasimov, Yulia V Dobryakov. Alzheimer's Disease: An Attempt of Total Recall. Journal of Alzheimer's disease : JAD. 2024-09-13. PMID:39269841. |
we also explore the alternative possibility of compensatory protective changes that may occur in these neurons to support cholinergic function in the forebrain of subjects with ad. |
2024-09-13 |
2024-09-16 |
human |
| Mohammed Zacky Ariffin, Si Yun Ng, Hamzah Nadia, Darrel Koh, Natasha Loh, Naomi Michiko, Sanjay Khann. Neurokinin1 - cholinergic receptor mechanisms in the medial Septum-Dorsal hippocampus axis mediates experimental neuropathic pain. Neurobiology of pain (Cambridge, Mass.). vol 16. 2024-09-03. PMID:39224764. |
the neurokinin-1 receptors (nk1rs) in the forebrain medial septum (ms) region are localized exclusively on cholinergic neurons that partly project to the hippocampus and the cingulate cortex (cg), regions implicated in nociception. |
2024-09-03 |
2024-09-05 |
rat |
| Mohammed Zacky Ariffin, Si Yun Ng, Hamzah Nadia, Darrel Koh, Natasha Loh, Naomi Michiko, Sanjay Khann. Neurokinin1 - cholinergic receptor mechanisms in the medial Septum-Dorsal hippocampus axis mediates experimental neuropathic pain. Neurobiology of pain (Cambridge, Mass.). vol 16. 2024-09-03. PMID:39224764. |
conversely, pre-emptive destruction of septal cholinergic neurons attenuated the development of ph in the cci model that also prevented the expression of cellular markers of nociception in the spinal cord and the forebrain. |
2024-09-03 |
2024-09-05 |
rat |
| Niaz Mahmood, Jung-Hyun Choi, Pei You Wu, Sean W Dooling, Trent A Watkins, Ziying Huang, Jesse Lipman, Hanjie Zhao, Anqi Yang, Jake Silversmith, Yanis Inglebert, Constantinos Koumenis, Vijendra Sharma, Jean-Claude Lacaille, Wayne S Sossin, Arkady Khoutorsky, R Anne McKinney, Mauro Costa-Mattioli, Nahum Sonenber. The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 31. 2024-07-25. PMID:39047038. |
we found that the removal of atf4 from forebrain excitatory neurons (but not from inhibitory neurons, cholinergic neurons, or astrocytes) enhances ltm formation. |
2024-07-25 |
2024-07-28 |
Not clear |
| Chao Zhang, R Michael Burge. Cholinergic modulation in the vertebrate auditory pathway. Frontiers in cellular neuroscience. vol 18. 2024-07-04. PMID:38962512. |
despite its apparent ubiquity in auditory circuitry, investigation of the roles of this cholinergic network has been mainly focused on the inner ear or forebrain structures, while less attention has been directed at regions between the cochlear nuclei and midbrain. |
2024-07-04 |
2024-07-10 |
Not clear |
| Laszlo Zaborszky, Peter Varsanyi, Kevin Alloway, Candice Chavez, Matthew Gielow, Peter Gombkoto, Hideki Kondo, Zoltan Nadasd. Functional architecture of the forebrain cholinergic system in rodents. Research square. 2024-07-01. PMID:38947053. |
functional architecture of the forebrain cholinergic system in rodents. |
2024-07-01 |
2024-07-03 |
rat |
| Fulton T Crews, Victoria Macht, Ryan P Vetren. Epigenetic regulation of microglia and neurons by proinflammatory signaling following adolescent intermittent ethanol (AIE) exposure and in human AUD. Advances in drug and alcohol research. vol 4. 2024-03-25. PMID:38524847. |
aie increases hmgb1-tlr4 signaling in forebrain, reducing cholinergic neurons by silencing multiple cholinergic defining genes through upregulation of re-1 silencing factor (rest), a transcription inhibitor known to regulate neuronal differentiation. |
2024-03-25 |
2024-03-27 |
human |
| Kurt A Jellinge. Pathobiology of Cognitive Impairment in Parkinson Disease: Challenges and Outlooks. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203667. |
longitudinal cognitive decline is associated with frontostriatal and limbic affections, white matter microlesions and changes between multiple functional neuronal networks, including thalamo-insular, frontoparietal and attention networks, the cholinergic forebrain and the noradrenergic system. |
2024-01-11 |
2024-01-13 |
Not clear |
| Aditya Nair, Yue Yang Teo, George J Augustine, Martin Gra. A functional logic for neurotransmitter corelease in the cholinergic forebrain pathway. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 28. 2023-07-03. PMID:37399414. |
a functional logic for neurotransmitter corelease in the cholinergic forebrain pathway. |
2023-07-03 |
2023-08-14 |
Not clear |
| Aditya Nair, Yue Yang Teo, George J Augustine, Martin Gra. A functional logic for neurotransmitter corelease in the cholinergic forebrain pathway. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 28. 2023-07-03. PMID:37399414. |
the circuit computations underlying cholinergic actions are confounded by recent findings that forebrain cholinergic neurons corelease both acetylcholine (ach) and gaba. |
2023-07-03 |
2023-08-14 |
Not clear |
| Sudesna Chakraborty, Roy A M Haast, Prabesh Kanel, Ali R Khan, Taylor W Schmit. Multimodal gradients of human basal forebrain connectivity. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292595. |
we therefore used high resolution 7t diffusion and resting state functional mri in humans to examine multimodal gradients of forebrain cholinergic connectivity with the neocortex. |
2023-06-09 |
2023-08-14 |
human |
| Lanfang Li, Bing Zhang, Xiaomei Tang, Quntao Yu, Aodi He, Youming Lu, Xinyan L. A selective degeneration of cholinergic neurons mediated by NRADD in an Alzheimer's disease mouse model. Cell insight. vol 1. issue 6. 2023-05-16. PMID:37193353. |
cholinergic neurons in the basal forebrain constitute a major source of cholinergic inputs to the forebrain, modulate diverse functions including sensory processing, memory and attention, and are vulnerable to alzheimer's disease (ad). |
2023-05-16 |
2023-08-14 |
mouse |
| Mikel L Olson, Bretton Badenoch, Megan Blatti, Christine Buching, Nic Gleww. Muscarinic Cholinergic Receptor Antagonism Impairs Spatial Memory Retrieval and Minimizes Retrieval-Induced Alterations in Matrix Metalloproteinase-9. Behavioural brain research. 2023-04-29. PMID:37119978. |
cholinergic dysfunction in the hippocampus causes memory impairment, and degradation of the forebrain cholinergic system has been implicated in several neurological disorders. |
2023-04-29 |
2023-08-14 |
rat |
| Adam J Granger, Karen Mao, Jessica L Saulnier, Morgan E Hines, Bernardo L Sabatin. Developmental regulation of GABAergic gene expression in forebrain cholinergic neurons. Frontiers in neural circuits. vol 17. 2023-04-10. PMID:37035505. |
developmental regulation of gabaergic gene expression in forebrain cholinergic neurons. |
2023-04-10 |
2023-08-14 |
mouse |
| Adam J Granger, Karen Mao, Jessica L Saulnier, Morgan E Hines, Bernardo L Sabatin. Developmental regulation of GABAergic gene expression in forebrain cholinergic neurons. Frontiers in neural circuits. vol 17. 2023-04-10. PMID:37035505. |
transgene expression suggests that nearly all forebrain cholinergic neurons in mice at some point in development express |
2023-04-10 |
2023-08-14 |
mouse |
| Tomonari Sumi, Kouji Harad. Muscarinic acetylcholine receptor-dependent and NMDA receptor-dependent LTP and LTD share the common AMPAR trafficking pathway. iScience. vol 26. issue 3. 2023-03-03. PMID:36866246. |
the forebrain cholinergic system promotes higher brain function in part by signaling through the m |
2023-03-03 |
2023-08-14 |
Not clear |
| Nima Salimi-Nezhad, Stephan Missault, Anaïs Notario Reinoso, Atefe Hassani, Mahmood Amiri, Georgios A Keliri. The impact of selective and non-selective medial septum stimulation on hippocampal neuronal oscillations: A study based on modeling and experiments. Neurobiology of disease. 2023-02-23. PMID:36822547. |
the medial septum (ms) in the forebrain provides major cholinergic input to the hpc and has been shown to play a significant role in generating oscillations in hippocampal neurons. |
2023-02-23 |
2023-08-14 |
rat |
| Victoria Macht, Ryan Vetreno, Natalie Elchert, Rachael Fisher, Fulton Crew. Indomethacin restores loss of hippocampal neurogenesis and cholinergic innervation and reduces innate immune expression and reversal learning deficits in adult male and female rats following adolescent ethanol exposure. Alcoholism, clinical and experimental research. 2023-02-17. PMID:36799290. |
adolescent intermittent ethanol (aie) exposure causes long-term changes in the brain and behavior of adult male rodents, including persistent induction of innate immune pathways, reductions in hippocampal neurogenic and forebrain cholinergic neuronal markers, and reversal learning deficits. |
2023-02-17 |
2023-08-14 |
rat |
| Victoria Macht, Ryan Vetreno, Natalie Elchert, Rachael Fisher, Fulton Crew. Indomethacin restores loss of hippocampal neurogenesis and cholinergic innervation and reduces innate immune expression and reversal learning deficits in adult male and female rats following adolescent ethanol exposure. Alcoholism, clinical and experimental research. 2023-02-17. PMID:36799290. |
the current study tests the hypothesis that proinflammatory induction mediates aie-induced (1) loss of adult neurogenesis (i.e., doublecortin (dcx) expressing immature neurons), (2) reductions in forebrain and hippocampal cholinergic markers, and (3) reversal learning deficits. |
2023-02-17 |
2023-08-14 |
rat |
| Andrea Becchetti, Laura Clara Grandi, Marta Cerina, Alida Amade. NICOTINIC ACETYLCHOLINE RECEPTORS AND EPILEPSY. Pharmacological research. 2023-02-16. PMID:36796465. |
the ascending cholinergic projections exert potent control of forebrain excitability, and wide evidence implicates nachr dysregulation as both cause and effect of epileptiform activity. |
2023-02-16 |
2023-08-14 |
Not clear |