| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susan E Maloney, Eakta Khangura, Joseph D Doughert. The RNA-binding protein Celf6 is highly expressed in diencephalic nuclei and neuromodulatory cell populations of the mouse brain. Brain structure & function. vol 221. issue 4. 2017-10-03. PMID:25682262. |
the greatest protein expression was observed in distinct nuclei of the diencephalon and neuromodulatory cell populations of the midbrain and hindbrain, with clear expression in dopaminergic, noradrenergic, histaminergic, serotonergic and cholinergic populations, and a variety of presumptive peptidergic cells of the hypothalamus. |
2017-10-03 |
2023-08-13 |
mouse |
| Natalia Omelchenko, Priya Roy, Judith Joyce Balcita-Pedicino, Samuel Poloyac, Susan R Sesac. Impact of prenatal nicotine on the structure of midbrain dopamine regions in the rat. Brain structure & function. vol 221. issue 4. 2017-10-03. PMID:25716298. |
certain sequelae of prenatal nic exposure suggest an impact on the development of the midbrain dopamine (da) system, which receives a robust cholinergic innervation from the mesopontine tegmentum. |
2017-10-03 |
2023-08-13 |
human |
| Leigh-Anne Dell, Nina Patzke, Muhammad A Spocter, Mads F Bertelsen, Jerome M Siegel, Paul R Mange. Organization of the sleep-related neural systems in the brain of the river hippopotamus (Hippopotamus amphibius): A most unusual cetartiodactyl species. The Journal of comparative neurology. vol 524. issue 10. 2017-08-30. PMID:26588600. |
these features, along with novel cholinergic nuclei in the intralaminar nuclei of the dorsal thalamus and the ventral tegmental area of the midbrain, as well as a major expansion of the hypothalamic cholinergic nuclei and a large laterodorsal tegmental nucleus of the pons that has both parvocellular and magnocellular cholinergic neurons, indicates an unusual sleep phenomenology for the hippopotamus. |
2017-08-30 |
2023-08-13 |
Not clear |
| Martin Engel, Dzung Do-Ha, Sonia Sanz Muñoz, Lezanne Oo. Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research. Cellular and molecular life sciences : CMLS. vol 73. issue 19. 2017-08-04. PMID:27154043. |
we have analyzed the literature that describes differentiation of human pluripotent stem cells into three neural cell types that are commonly used to study diseases, including forebrain cholinergic neurons for alzheimer's disease, midbrain dopaminergic neurons for parkinson's disease and cortical astrocytes for neurodegenerative and psychiatric disorders. |
2017-08-04 |
2023-08-13 |
human |
| Cheng Xiao, Jounhong Ryan Cho, Chunyi Zhou, Jennifer B Treweek, Ken Chan, Sheri L McKinney, Bin Yang, Viviana Gradinar. Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways. Neuron. vol 90. issue 2. 2017-06-19. PMID:27100197. |
cholinergic mesopontine signals govern locomotion and reward through dissociable midbrain pathways. |
2017-06-19 |
2023-08-13 |
Not clear |
| Cheng Xiao, Jounhong Ryan Cho, Chunyi Zhou, Jennifer B Treweek, Ken Chan, Sheri L McKinney, Bin Yang, Viviana Gradinar. Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways. Neuron. vol 90. issue 2. 2017-06-19. PMID:27100197. |
the mesopontine tegmentum, including the pedunculopontine and laterodorsal tegmental nuclei (ppn and ldt), provides major cholinergic inputs to midbrain and regulates locomotion and reward. |
2017-06-19 |
2023-08-13 |
Not clear |
| Cheng Xiao, Jounhong Ryan Cho, Chunyi Zhou, Jennifer B Treweek, Ken Chan, Sheri L McKinney, Bin Yang, Viviana Gradinar. Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways. Neuron. vol 90. issue 2. 2017-06-19. PMID:27100197. |
to delineate the underlying projection-specific circuit mechanisms, we employed optogenetics to control mesopontine cholinergic neurons at somata and at divergent projections within distinct midbrain areas. bidirectional manipulation of ppn cholinergic cell bodies exerted opposing effects on locomotor behavior and reinforcement learning. |
2017-06-19 |
2023-08-13 |
Not clear |
| Yael Abreu-Villaça, Monique Correa-Santos, Ana C Dutra-Tavares, Danielle Paes-Branco, Andre Nunes-Freitas, Alex C Manhães, Cláudio C Filgueiras, Anderson Ribeiro-Carvalh. A ten fold reduction of nicotine yield in tobacco smoke does not spare the central cholinergic system in adolescent mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 52. 2017-03-27. PMID:27287270. |
cholinergic biomarkers were assessed in the cerebral cortex and midbrain by the end of exposure (pn45), at short- (pn50) and long-term (pn75) deprivation. |
2017-03-27 |
2023-08-13 |
mouse |
| Duncan A A MacLaren, David I G Wilson, Philip Win. Selective lesions of the cholinergic neurons within the posterior pedunculopontine do not alter operant learning or nicotine sensitization. Brain structure & function. vol 221. issue 3. 2016-12-19. PMID:25586659. |
cholinergic neurons within the pedunculopontine tegmental nucleus have been implicated in a range of functions, including behavioral state control, attention, and modulation of midbrain and basal ganglia systems. |
2016-12-19 |
2023-08-13 |
rat |
| Rachel J Sizemore, Rong Zhang, Naili Lin, Liping Goddard, Timothy Wastney, Louise C Parr-Brownlie, John N J Reynolds, Dorothy E Oorscho. Marked differences in the number and type of synapses innervating the somata and primary dendrites of midbrain dopaminergic neurons, striatal cholinergic interneurons, and striatal spiny projection neurons in the rat. The Journal of comparative neurology. vol 524. issue 5. 2016-10-24. PMID:26355230. |
marked differences in the number and type of synapses innervating the somata and primary dendrites of midbrain dopaminergic neurons, striatal cholinergic interneurons, and striatal spiny projection neurons in the rat. |
2016-10-24 |
2023-08-13 |
rat |
| Matthew J Crossley, Jon C Horvitz, Peter D Balsam, F Gregory Ashb. Expanding the role of striatal cholinergic interneurons and the midbrain dopamine system in appetitive instrumental conditioning. Journal of neurophysiology. vol 115. issue 1. 2016-10-18. PMID:26467514. |
expanding the role of striatal cholinergic interneurons and the midbrain dopamine system in appetitive instrumental conditioning. |
2016-10-18 |
2023-08-13 |
Not clear |
| Patrick P Gao, Jevin W Zhang, Shu-Juan Fan, Dan H Sanes, Ed X W. Auditory midbrain processing is differentially modulated by auditory and visual cortices: An auditory fMRI study. NeuroImage. vol 123. 2016-08-11. PMID:26306991. |
in the central auditory system, the auditory cortex contains direct and indirect pathways (via brainstem cholinergic cells) to nuclei of the auditory midbrain, called the inferior colliculus (ic). |
2016-08-11 |
2023-08-13 |
rat |
| Marc Deffains, Hagai Bergma. Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 8. 2016-05-06. PMID:26095280. |
basal ganglia disorders are often associated with an imbalance between the midbrain dopaminergic and striatal cholinergic systems. |
2016-05-06 |
2023-08-13 |
Not clear |
| Marc Deffains, Hagai Bergma. Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 8. 2016-05-06. PMID:26095280. |
in contrast to the extensive research and literature on the consequences of a malfunction of midbrain dopaminergic signaling on the plasticity of the cortico-striatal synapse, very little is known about the role of striatal cholinergic interneurons in normal and pathological control of cortico-striatal transmission. |
2016-05-06 |
2023-08-13 |
Not clear |
| Michael P Stryke. A Neural Circuit That Controls Cortical State, Plasticity, and the Gain of Sensory Responses in Mouse. Cold Spring Harbor symposia on quantitative biology. vol 79. 2016-03-14. PMID:25948638. |
the circuit consists of projections ascending from the midbrain locomotor region (mlr) to the basal forebrain, activating cholinergic and perhaps other projections to excite inhibitory interneurons expressing vasoactive intestinal peptide (vip) in the visual cortex. |
2016-03-14 |
2023-08-13 |
mouse |
| S Ma, A L Gundlac. Ascending control of arousal and motivation: role of nucleus incertus and its peptide neuromodulators in behavioural responses to stress. Journal of neuroendocrinology. vol 27. issue 6. 2016-03-01. PMID:25612218. |
established modulators of arousal include the cholinergic, serotonergic, noradrenergic and dopaminergic networks originating in the pons and midbrain. |
2016-03-01 |
2023-08-13 |
Not clear |
| Sybren F de Kloet, Huibert D Mansvelder, Taco J De Vrie. Cholinergic modulation of dopamine pathways through nicotinic acetylcholine receptors. Biochemical pharmacology. vol 97. issue 4. 2016-02-09. PMID:26208783. |
profound modulatory cholinergic input from the pedunculopontine and laterodorsal tegmentum to dopaminergic midbrain nuclei as well as local cholinergic interneuron projections to dopamine neuron axons in the striatum may play a major role in the effects of nicotine. |
2016-02-09 |
2023-08-13 |
Not clear |
| Adrienn Kovács, Csilla Bordás, Balázs Pá. Cholinergic and endocannabinoid neuromodulatory effects overlap on neurons of the pedunculopontine nucleus of mice. Neuroreport. vol 26. issue 5. 2015-11-16. PMID:25730677. |
the pedunculopontine nucleus (ppn) is a part of the reticular activating system and one of the main sources of the cholinergic fibers in the midbrain, while it is also subject to cholinergic modulation. |
2015-11-16 |
2023-08-13 |
mouse |
| David Sherman, Patrick M Fuller, Jacob Marcus, Jun Yu, Ping Zhang, Nancy L Chamberlin, Clifford B Saper, Jun L. Anatomical Location of the Mesencephalic Locomotor Region and Its Possible Role in Locomotion, Posture, Cataplexy, and Parkinsonism. Frontiers in neurology. vol 6. 2015-07-09. PMID:26157418. |
the pedunculopontine tegmental nucleus (ppt) cholinergic neurons and midbrain extrapyramidal area (mea) have been suggested to form the neuroanatomical basis for the mlr, but direct evidence for the role of these structures in locomotor behavior has been lacking. |
2015-07-09 |
2023-08-13 |
rat |
| Astra S Bryant, C Alex Goddard, John R Huguenard, Eric I Knudse. Cholinergic control of gamma power in the midbrain spatial attention network. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 2. 2015-04-07. PMID:25589769. |
cholinergic control of gamma power in the midbrain spatial attention network. |
2015-04-07 |
2023-08-13 |
Not clear |