| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rita Bardoni, Alessia Ghirri, Micaela Zonta, Chiara Betelli, Giovanni Vitale, Valentina Ruggieri, Maurizio Sandrini, Giorgio Carmignot. Glutamate-mediated astrocyte-to-neuron signalling in the rat dorsal horn. The Journal of physiology. vol 588. issue Pt 5. 2010-06-02. PMID:20083514. |
by using patch-clamp and confocal microscope calcium imaging techniques in rat spinal cord slices, we monitored the activity of dorsal horn lamina ii neurons following astrocyte activation. |
2010-06-02 |
2023-08-12 |
rat |
| Robin E White, Dana M McTigue, Lyn B Jakema. Regional heterogeneity in astrocyte responses following contusive spinal cord injury in mice. The Journal of comparative neurology. vol 518. issue 8. 2010-06-01. PMID:20151365. |
regional heterogeneity in astrocyte responses following contusive spinal cord injury in mice. |
2010-06-01 |
2023-08-12 |
mouse |
| Feng Jiang, Tong Liu, Ming Cheng, Xue-Yan Pang, Zhan-Tao Bai, Jing-Jing Zhou, Yong-Hua J. Spinal astrocyte and microglial activation contributes to rat pain-related behaviors induced by the venom of scorpion Buthus martensi Karch. European journal of pharmacology. vol 623. issue 1-3. 2010-02-22. PMID:19782067. |
the results showed that glial fibrillary acidic protein (gfap) immunoreactivity indicative astrocyte activation in bilateral spinal cord started to increase by day 3, peaked at day 7 and gradually reversed at day 14 following intraplantar injection of bmk venom. |
2010-02-22 |
2023-08-12 |
rat |
| Qi Xiao, Yang Du, Wutian Wu, Henry K Yi. Bone morphogenetic proteins mediate cellular response and, together with Noggin, regulate astrocyte differentiation after spinal cord injury. Experimental neurology. vol 221. issue 2. 2010-02-16. PMID:20005873. |
bone morphogenetic proteins mediate cellular response and, together with noggin, regulate astrocyte differentiation after spinal cord injury. |
2010-02-16 |
2023-08-12 |
mouse |
| Qi Xiao, Yang Du, Wutian Wu, Henry K Yi. Bone morphogenetic proteins mediate cellular response and, together with Noggin, regulate astrocyte differentiation after spinal cord injury. Experimental neurology. vol 221. issue 2. 2010-02-16. PMID:20005873. |
neurosphere culture from adult mouse spinal cord showed that bmp-4 promoted astrocyte differentiation from nscs while suppressing production of neurons and oligodendrocytes. |
2010-02-16 |
2023-08-12 |
mouse |
| Sarah A Busch, Kevin P Horn, Fernando X Cuascut, Alicia L Hawthorne, Lianhua Bai, Robert H Miller, Jerry Silve. Adult NG2+ cells are permissive to neurite outgrowth and stabilize sensory axons during macrophage-induced axonal dieback after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 1. 2010-02-04. PMID:20053907. |
interestingly, after spinal cord injury, the regenerating front of axons is typically found in areas rich in ed1+ cells, but devoid of reactive astrocyte processes. |
2010-02-04 |
2023-08-12 |
Not clear |
| Jun-Wei Zeng, Xiao-Hong Liu, Yan-Dong Zhao, Zhi Xiao, Wen-Juan He, Zhi-An Hu, Huai-Zhen Rua. Role of P2Y1 receptor in astroglia-to-neuron signaling at dorsal spinal cord. Journal of neuroscience research. vol 87. issue 12. 2010-01-12. PMID:19396875. |
in the present study, the actions of adenosine 5'-o-(2-thiodiphosphate) (adpbetas)-activated astrocyte conditioned medium (adpbetas-acm) on cultured dorsal spinal cord neurons were evaluated by using confocal laser scanning microscopy and whole-cell patch-clamp recording. |
2010-01-12 |
2023-08-12 |
Not clear |
| Smita Pathak, Rosa Tolentino, Kim Nguyen, Lorenzo D'Amico, Erin Barron, Lingyun Cheng, William R Freeman, Gabriel A Silv. Quantum dot labeling and imaging of glial fibrillary acidic protein intermediate filaments and gliosis in the rat neural retina and dissociated astrocytes. Journal of nanoscience and nanotechnology. vol 9. issue 8. 2009-12-24. PMID:19928184. |
we have optimized and used anti-gfap functionalized quantum dots for specific labeling of intermediate filaments in astrocyte and müller glial cells in sections of intact rat neural sensory retina and dissociated primary spinal cord astrocytes. |
2009-12-24 |
2023-08-12 |
rat |
| Monika Bradl, Tatsuro Misu, Toshiyuki Takahashi, Mitsutoshi Watanabe, Simone Mader, Markus Reindl, Milena Adzemovic, Jan Bauer, Thomas Berger, Kazuo Fujihara, Yasuto Itoyama, Hans Lassman. Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo. Annals of neurology. vol 66. issue 5. 2009-12-21. PMID:19937948. |
severe inflammation and astrocyte loss with profound demyelination in spinal cord and optic nerves are typical pathological features of neuromyelitis optica (nmo). |
2009-12-21 |
2023-08-12 |
Not clear |
| Pennelope K Blakely, Bette K Kleinschmidt-DeMasters, Kenneth L Tyler, David N Iran. Disrupted glutamate transporter expression in the spinal cord with acute flaccid paralysis caused by West Nile virus infection. Journal of neuropathology and experimental neurology. vol 68. issue 10. 2009-12-04. PMID:19918118. |
these findings suggest that wnv infection results in local immune activation within the spinal cord that in turn causes a failure of astrocyte glutamate reuptake even as the number of astrocytes increases; rising extracellular glutamate levels may then drive excitotoxic injury of both infected and uninfected anterior horn cells. |
2009-12-04 |
2023-08-12 |
human |
| Séverine Deforges, Julien Branchu, Olivier Biondi, Clément Grondard, Claude Pariset, Sylvie Lécolle, Philippe Lopes, Pierre-Paul Vidal, Christophe Chanoine, Frédéric Charbonnie. Motoneuron survival is promoted by specific exercise in a mouse model of amyotrophic lateral sclerosis. The Journal of physiology. vol 587. issue Pt 14. 2009-10-15. PMID:19491245. |
furthermore, the swimming programme preserved astrocyte and oligodendrocyte populations in als spinal cord. |
2009-10-15 |
2023-08-12 |
mouse |
| W Xie, J A Strong, J-M Zhan. Early blockade of injured primary sensory afferents reduces glial cell activation in two rat neuropathic pain models. Neuroscience. vol 160. issue 4. 2009-08-14. PMID:19303429. |
local perfusion in the snl model also significantly reduced microglia activation (ox-42 immunoreactivity) on day 3 and astrocyte activation (gfap immunoreactivity) on day 10 in the corresponding dorsal spinal cord. |
2009-08-14 |
2023-08-12 |
rat |
| Andreas Hald, Signe Nedergaard, Rikke R Hansen, Ming Ding, Anne-Marie Heegaar. Differential activation of spinal cord glial cells in murine models of neuropathic and cancer pain. European journal of pain (London, England). vol 13. issue 2. 2009-04-10. PMID:18499488. |
in the present report, we examined the time course of spinal cord glial activation in three different murine pain models to investigate if microglial activation is a general prerequisite for astrocyte activation in pain models. |
2009-04-10 |
2023-08-12 |
Not clear |
| Li-Kai Tsai, Ming-Shiun Tsai, Chen-Hung Ting, Hung L. Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice. Journal of molecular medicine (Berlin, Germany). vol 86. issue 11. 2009-04-08. PMID:18649067. |
vpa probably induced neurogenesis and promoted astrocyte proliferation in the spinal cord of type iii-like sma mice, which might contribute to therapeutic effects by enhancing neuroprotection. |
2009-04-08 |
2023-08-12 |
mouse |
| Simone Codeluppi, Camilla I Svensson, Michael P Hefferan, Fatima Valencia, Morgan D Silldorff, Masakatsu Oshiro, Martin Marsala, Elena B Pasqual. The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 4. 2009-04-08. PMID:19176818. |
here we show that in cultures of adult spinal cord astrocytes egf activates the mtor pathway, a key regulator of astrocyte physiology. |
2009-04-08 |
2023-08-12 |
rat |
| Hideo Kobayashi, Sharmila Chattopadhyay, Kinshi Kato, Jennifer Dolkas, Shin-Ichi Kikuchi, Robert R Myers, Veronica I Shubaye. MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage. Molecular and cellular neurosciences. vol 39. issue 4. 2009-01-30. PMID:18817874. |
acute and long-term therapy with gm6001 (broad-spectrum mmp inhibitor) protected from injury-induced mbp degradation, caspase-mediated apoptosis, macrophage infiltration in the spinal nerve and inhibited astrocyte activation in the spinal cord. |
2009-01-30 |
2023-08-12 |
mouse |
| Max R Bennett, Les Farnell, William G Gibso. A quantitative model of cortical spreading depression due to purinergic and gap-junction transmission in astrocyte networks. Biophysical journal. vol 95. issue 12. 2009-01-21. PMID:18952785. |
we show that the characteristics of sd and the accompanying extracellular ionic changes can be accommodated by such a model-whether astrocyte transmission is principally through the release of atp, as in archicortex (hippocampus) and spinal cord, or via gap junctions, as in the neocortex. |
2009-01-21 |
2023-08-12 |
Not clear |
| Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragaki. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nature neuroscience. vol 11. issue 11. 2008-12-19. PMID:18931666. |
these findings indicate the feasibility and efficacy of transplantation-based astrocyte replacement and show that targeted multisegmental cell delivery to the cervical spinal cord is a promising therapeutic strategy for slowing focal motor neuron loss associated with als. |
2008-12-19 |
2023-08-12 |
human |
| Ming-Der Perng, Shu-Fang Wen, Terry Gibbon, Jinte Middeldorp, Jacqueline Sluijs, Elly M Hol, Roy A Quinla. Glial fibrillary acidic protein filaments can tolerate the incorporation of assembly-compromised GFAP-delta, but with consequences for filament organization and alphaB-crystallin association. Molecular biology of the cell. vol 19. issue 10. 2008-12-01. PMID:18685083. |
in a range of immortalized and transformed astrocyte derived cell lines and human spinal cord, we show that gfap-delta is naturally part of the endogenous intermediate filaments, although levels were low (approximately 10%). |
2008-12-01 |
2023-08-12 |
human |
| Ming-Chu Tsai, Li-Fen Shen, Huai-Sheng Kuo, Henrich Cheng, Kin-Fu Cha. Involvement of acidic fibroblast growth factor in spinal cord injury repair processes revealed by a proteomics approach. Molecular & cellular proteomics : MCP. vol 7. issue 9. 2008-09-30. PMID:18482974. |
noticeably proteins involved in the process of secondary injury, such as astrocyte activation (glial fibrillary acidic protein), inflammation (s100b), and scar formation (keratan sulfate proteoglycan lumican), which lead to the blocking of injured spinal cord regeneration, were down-regulated in the contusive spinal cord after treatment with afgf. |
2008-09-30 |
2023-08-12 |
rat |