| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian Cui, Shan Ou, Wen-Juan He, Lu Du, Yan-Dong Zhao, Huai-Zhen Rua. Prevention of extracellular ADP-induced ATP accumulation of the cultured rat spinal astrocytes via P2Y(1)-mediated inhibition of AMPK. Neuroscience letters. vol 503. issue 3. 2012-01-20. PMID:21896310. |
p2y(1) is probably an important subtype of purinergic receptors (p2rs) in modulation of the astrocyte activation in spinal cord. |
2012-01-20 |
2023-08-12 |
rat |
| Robin E White, Meghan Rao, John C Gensel, Dana M McTigue, Brian K Kaspar, Lyn B Jakema. Transforming growth factor α transforms astrocytes to a growth-supportive phenotype after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 42. 2011-12-08. PMID:22016551. |
we have shown that intrathecal administration of transforming growth factor α (tgfα) to the contused mouse spinal cord can enhance astrocyte infiltration and axonal growth within the injury site, but the mechanisms of these effects are not well understood. |
2011-12-08 |
2023-08-12 |
mouse |
| Zin Z Khaing, Brian D Milman, Jennifer E Vanscoy, Stephanie K Seidlits, Raymond J Grill, Christine E Schmid. High molecular weight hyaluronic acid limits astrocyte activation and scar formation after spinal cord injury. Journal of neural engineering. vol 8. issue 4. 2011-11-23. PMID:21753237. |
high molecular weight hyaluronic acid limits astrocyte activation and scar formation after spinal cord injury. |
2011-11-23 |
2023-08-12 |
rat |
| Laura Ferraiuolo, Adrian Higginbottom, Paul R Heath, Sian Barber, David Greenald, Janine Kirby, Pamela J Sha. Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis. Brain : a journal of neurology. vol 134. issue Pt 9. 2011-11-08. PMID:21908873. |
first, there was evidence of metabolic dysregulation and, in particular, impairment of the astrocyte lactate efflux transporter, with resultant decrease of spinal cord lactate levels. |
2011-11-08 |
2023-08-12 |
mouse |
| Alan S Verkman, Julien Ratelade, Andrea Rossi, Hua Zhang, Lukmanee Tradtranti. Aquaporin-4: orthogonal array assembly, CNS functions, and role in neuromyelitis optica. Acta pharmacologica Sinica. vol 32. issue 6. 2011-09-30. PMID:21552296. |
phenotype analysis of aqp4-null mice indicates the involvement of aqp4 in brain and spinal cord water balance, astrocyte migration, neural signal transduction and neuroinflammation. |
2011-09-30 |
2023-08-12 |
mouse |
| Hao Yang, Zhe Liang, Jingwen Li, Xiping Cheng, Na Luo, Gong J. Optimized and efficient preparation of astrocyte cultures from rat spinal cord. Cytotechnology. vol 52. issue 2. 2011-07-14. PMID:19002867. |
optimized and efficient preparation of astrocyte cultures from rat spinal cord. |
2011-07-14 |
2023-08-12 |
rat |
| Stephen J A Davies, Chung-Hsuan Shih, Mark Noble, Margot Mayer-Proschel, Jeannette E Davies, Christoph Prosche. Transplantation of specific human astrocytes promotes functional recovery after spinal cord injury. PloS one. vol 6. issue 3. 2011-07-05. PMID:21407803. |
these findings are consistent with our previous studies of transplanting specific subtypes of rodent glial precursor derived astrocytes into sites of spinal cord injury, and indicate a remarkable conservation from rat to human of functional differences between astrocyte subtypes. |
2011-07-05 |
2023-08-12 |
human |
| Yaping Wang, Xiaoxin Cheng, Qian He, Yiyan Zheng, Dong H Kim, Scott R Whittemore, Qilin L Ca. Astrocytes from the contused spinal cord inhibit oligodendrocyte differentiation of adult oligodendrocyte precursor cells by increasing the expression of bone morphogenetic proteins. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 16. 2011-06-30. PMID:21508230. |
in the present study, we show that reactive astrocytes from the injured rat spinal cord or their conditioned media inhibit ol differentiation of adult opcs with concurrent promotion of astrocyte differentiation. |
2011-06-30 |
2023-08-12 |
rat |
| K M Ramos, M T Lewis, K N Morgan, N Y Crysdale, J L Kroll, F R Taylor, J A Harrison, E M Sloane, S F Maier, L R Watkin. Spinal upregulation of glutamate transporter GLT-1 by ceftriaxone: therapeutic efficacy in a range of experimental nervous system disorders. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20547213. |
lastly, ceftriaxone normalized cci- and eae-induced astrocyte activation in lumbar spinal cord. |
2011-04-18 |
2023-08-12 |
rat |
| Zhe Li, Zheng-Yu Fang, Liang Xiong, Xiao-Lin Huan. Spinal cord injury-induced astrocyte migration and glial scar formation: effects of magnetic stimulation frequency. Indian journal of biochemistry & biophysics. vol 47. issue 6. 2011-03-15. PMID:21355419. |
spinal cord injury-induced astrocyte migration and glial scar formation: effects of magnetic stimulation frequency. |
2011-03-15 |
2023-08-12 |
rat |
| Zhe Li, Zheng-Yu Fang, Liang Xiong, Xiao-Lin Huan. Spinal cord injury-induced astrocyte migration and glial scar formation: effects of magnetic stimulation frequency. Indian journal of biochemistry & biophysics. vol 47. issue 6. 2011-03-15. PMID:21355419. |
activation of the erk1/2 signaling pathway is proposed to mediate astrocyte migration and glial scar formation in response to spinal cord injury. |
2011-03-15 |
2023-08-12 |
rat |
| Louis Doré-Savard, Valérie Otis, Karine Belleville, Myriam Lemire, Mélanie Archambault, Luc Tremblay, Jean-François Beaudoin, Nicolas Beaudet, Roger Lecomte, Martin Lepage, Louis Gendron, Philippe Sarre. Behavioral, medical imaging and histopathological features of a new rat model of bone cancer pain. PloS one. vol 5. issue 10. 2011-03-07. PMID:21048940. |
bone remodeling was accompanied by c-fos (spinal) and atf3 (drg) neuronal activation, sustained by astrocyte (gfap) and microglia (iba1) reactivity in lumbar spinal cord. |
2011-03-07 |
2023-08-12 |
human |
| Julio Gómez-Soriano, Eider Goiriena, Julian Taylo. Spasticity therapy reacts to astrocyte GluA1 receptor upregulation following spinal cord injury. British journal of pharmacology. vol 161. issue 5. 2011-02-10. PMID:20662840. |
spasticity therapy reacts to astrocyte glua1 receptor upregulation following spinal cord injury. |
2011-02-10 |
2023-08-12 |
Not clear |
| Julio Gómez-Soriano, Eider Goiriena, Julian Taylo. Spasticity therapy reacts to astrocyte GluA1 receptor upregulation following spinal cord injury. British journal of pharmacology. vol 161. issue 5. 2011-02-10. PMID:20662840. |
although further validation is required, the appropriate choice of ampa receptor antagonists for treatment of stretch hyperreflexia based on our recent understanding of reactive astrocyte neurobiology following spinal cord injury may lead to the development of a better adjunct clinical therapy for spasticity without the side effects of intrathecal baclofen therapy. |
2011-02-10 |
2023-08-12 |
Not clear |
| Emma East, Daniela Blum de Oliveira, Jon P Golding, James B Phillip. Alignment of astrocytes increases neuronal growth in three-dimensional collagen gels and is maintained following plastic compression to form a spinal cord repair conduit. Tissue engineering. Part A. vol 16. issue 10. 2011-01-20. PMID:20649441. |
after compression, astrocytes remained viable and aligned and supported neurite outgrowth, yielding a novel method for assembling aligned cellular constructs suitable for tissue engineering and highlighting the importance of astrocyte alignment as a possible future therapeutic intervention for spinal cord repair. |
2011-01-20 |
2023-08-12 |
Not clear |
| Theodore A Sarafian, Cindy Montes, Tetsuya Imura, Jingwei Qi, Giovanni Coppola, Daniel H Geschwind, Michael V Sofronie. Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro. PloS one. vol 5. issue 3. 2011-01-11. PMID:20224768. |
we have recently shown that stat3 is an important regulator of astrocyte reactivity after spinal cord injury in vivo[1]. |
2011-01-11 |
2023-08-12 |
Not clear |
| Eric Agius, Yann Decker, Chadi Soukkarieh, Cathy Soula, Philippe Cochar. Role of BMPs in controlling the spatial and temporal origin of GFAP astrocytes in the embryonic spinal cord. Developmental biology. vol 344. issue 2. 2010-08-30. PMID:20488175. |
in this study, we have defined spatially and temporally the origin of astrocytes and studied the role of bmps in astrocyte development in the embryonic chick spinal cord. |
2010-08-30 |
2023-08-12 |
chicken |
| Eric Agius, Yann Decker, Chadi Soukkarieh, Cathy Soula, Philippe Cochar. Role of BMPs in controlling the spatial and temporal origin of GFAP astrocytes in the embryonic spinal cord. Developmental biology. vol 344. issue 2. 2010-08-30. PMID:20488175. |
bmp treatment completely prevented astrocyte development from intermediate spinal cord explants at e5, whereas it promoted it at e6. |
2010-08-30 |
2023-08-12 |
chicken |
| Robin E White, Feng Qin Yin, Lyn B Jakema. TGF-alpha increases astrocyte invasion and promotes axonal growth into the lesion following spinal cord injury in mice. Experimental neurology. vol 214. issue 1. 2010-07-21. PMID:18647603. |
tgf-alpha increases astrocyte invasion and promotes axonal growth into the lesion following spinal cord injury in mice. |
2010-07-21 |
2023-08-12 |
mouse |
| Gabriela Pintar de Oliveira, Jessica Ruivo Maximino, Chin Jia Lin, Gerson Chad. A method to immunolabel rodent spinal cord neurons and glia for molecular study in specific laser microdissected cells involved in neurodegenerative disorders. Journal of molecular histology. vol 40. issue 3. 2010-06-08. PMID:19830581. |
however, an adequate protocol to allow morphological and molecular analysis of rodent spinal cord astrocyte, microglia and motoneurons remains a big challenge. |
2010-06-08 |
2023-08-12 |
human |