| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Larissa Marcely Gomes Cassiano, Marina da Silva Oliveira, Wellington Alves de Barros, Ângelo de Fátima, Roney Santos Coimbr. Neurotoxic effects of hallucinogenic drugs 25H-NBOMe and 25H-NBOH in organotypic hippocampal cultures. Heliyon. vol 9. issue 7. 2023-07-15. PMID:37449113. |
nbomes and nbohs are psychoactive drugs derived from phenethylamines and have hallucinogenic effects due to their strong agonism to serotonin 5-ht |
2023-07-15 |
2023-08-14 |
Not clear |
| You-Peng Fu, Yun Wan. Amphetamines abuse and depression: Focus on TRPC channels. Experimental neurology. 2023-03-30. PMID:36996966. |
amphetamines abuse can damage dopaminergic and serotonin neurons and cause neuroinflammation and neurotoxicity. |
2023-03-30 |
2023-08-14 |
Not clear |
| Liliana Dragomir, Virginia Marina, Mihaela Anghele, Aurelian-Dumitrache Anghele, Cosmina Alina Mosc. Incidence of Intoxications in the Emergency Department of Galati Hospital with Examples of Cardiovascular Effects of MDMA Intoxication. Diagnostics (Basel, Switzerland). vol 13. issue 5. 2023-03-11. PMID:36900084. |
mdma differs somewhat from traditional amphetamines in that it is not structurally similar to serotonin. |
2023-03-11 |
2023-08-14 |
Not clear |
| Laura B Kozell, Amy J Eshleman, Tracy L Swanson, Shelley H Bloom, Katherine M Wolfrum, Jennifer L Schmachtenberg, Randall J Olson, Aaron J Janowsky, Atheir I Abba. Pharmacologic activity of substituted tryptamines at 5-HT The Journal of pharmacology and experimental therapeutics. 2023-01-20. PMID:36669875. |
pharmacologic activity of substituted tryptamines at 5-ht novel psychoactive substances, including synthetic substituted tryptamines, represent a potential public health threat. |
2023-01-20 |
2023-08-14 |
Not clear |
| Daniel Rødbro Burmester, Martin Korsbak Madsen, Attila Szabo, Sagar Sanjay Aripaka, Dea Siggaard Stenbæk, Vibe G Frokjaer, Betina Elfving, Jens D Mikkelsen, Gitte Moos Knudsen, Patrick MacDonald Fishe. Subacute effects of a single dose of psilocybin on biomarkers of inflammation in healthy humans: An open-label preliminary investigation. Comprehensive psychoneuroendocrinology. vol 13. 2022-12-22. PMID:36545240. |
pre-clinical and initial studies in humans suggest that serotonin 2a receptor agonists, including serotonergic psychedelics, have anti-inflammatory effects. |
2022-12-22 |
2023-08-14 |
Not clear |
| Noémi Császár-Nagy, Petr Bob, István Bókko. A Multidisciplinary Hypothesis about Serotonergic Psychedelics. Is it Possible that a Portion of Brain Serotonin Comes From the Gut? Journal of integrative neuroscience. vol 21. issue 5. 2022-09-22. PMID:36137971. |
serotonergic psychedelics affect gut microbes that produce a temporary increase of 5-ht by their host enterochromaffin cells (ecs). |
2022-09-22 |
2023-08-14 |
Not clear |
| Michael Horseman, Ladan Panahi, George Udeani, Andrew S Tenpas, Rene Verduzco, Pooja H Patel, Daniela Z Bazan, Andrea Mora, Nephy Samuel, Anne-Cecile Mingle, Lisa R Leon, Joseph Varon, Salim Suran. Drug-Induced Hyperthermia Review. Cureus. vol 14. issue 7. 2022-08-30. PMID:36039261. |
the purpose of this article is to review the current literature and compare exertional heat stroke (ehs) to three of the most widely studied drug-induced hyperthermic syndromes: malignant hyperthermia (mh), neuroleptic malignant syndrome (nms), and serotonin syndrome (ss). drugs and drug classes that have been implicated in these conditions include amphetamines, diuretics, cocaine, antipsychotics, metoclopramide, selective serotonin reuptake inhibitors (ssris), tricyclic antidepressants (tcas), and many more. |
2022-08-30 |
2023-08-14 |
Not clear |
| Klára Šíchová, Kateřina Syrová, Edita Kofroňová, Nikola Pinterova-Leca, Čestmír Vejmola, Jitka Nykodemová, Petr Palivec, Lucie Olejníková, Hynek Danda, Pascal Jorratt, Šafanda Adam, Bui Quang Hiep, Kristýna Štefková-Mazochová, Markéta Končická, Martin Kuchař, Tomáš Páleníče. Pharmacokinetics, systemic toxicity, thermoregulation and acute behavioural effects of 25CN-NBOMe. Addiction biology. vol 27. issue 5. 2022-08-24. PMID:36001433. |
n-(2-methoxybenzyl)phenethylamines (nbomes) are a family of potent 5-ht |
2022-08-24 |
2023-08-14 |
Not clear |
| Eloir Gallegos, Marisol Ascona, Juana Monroy, Marta Elena Castro-Manrreza, Andrés Aragón-Martínez, María Elena Ayal. p-Chloroamphetamine decreases serotonin and induces apoptosis in granulosa cells and follicular atresia in prepubertal female rats. Reproductive toxicology (Elmsford, N.Y.). 2022-04-23. PMID:35460820. |
therefore, in this study, we investigated the effects of p-chloroamphetamine (pca), derived from amphetamines, on estradiol production, follicular development, apoptosis of granulosa cells, and serotonin 5-ht |
2022-04-23 |
2023-08-13 |
rat |
| Giuseppe Floresta, Vincenzo Abbat. Machine learning RSC advances. vol 11. issue 24. 2022-04-15. PMID:35424006. |
machine learning serotonergic psychedelics, substances exerting their effects primarily through the serotonin 2a receptor (5ht2ar), continue to comprise a substantial portion of reported new psychoactive substances (nps). |
2022-04-15 |
2023-08-13 |
Not clear |
| A C Stilmant, L Zhu, Y Gorur, B Cardos, M Yerna, D Al. [Fatal serotonin syndrome induced by ecstasy consumption]. Revue medicale de Liege. vol 77. issue 1. 2022-01-14. PMID:35029334. |
the use of amphetamines and amphetamine derivatives such as ecstasy can cause serotonin toxic syndrome, an uncommon but potentially serious adverse effect. |
2022-01-14 |
2023-08-13 |
Not clear |
| Eline Pottie, Christophe P Stov. In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5-HT Journal of neurochemistry. 2022-01-03. PMID:34978711. |
in vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5-ht serotonergic psychedelics are substances that induce alterations in mood, perception and thought, and have the activation of serotonin (5-ht) 2a receptors (5-ht |
2022-01-03 |
2023-08-13 |
Not clear |
| Marina Goulart da Silva, Guilherme Cabreira Daros, Rafael Mariano de Bitencour. Anti-inflammatory activity of ayahuasca: therapeutical implications in neurological and psychiatric diseases. Behavioural brain research. vol 400. 2021-11-15. PMID:33166569. |
as described in this narrative review, it is essentially constituted by β-carbolines and tryptamines, and it has therapeutic effects on behavioral disorders due to the inhibition of the monoamine oxidase enzyme and the activation of 5-hydroxytryptamine receptors, demonstrated through preclinical and clinical studies. |
2021-11-15 |
2023-08-13 |
Not clear |
| b' Kl\\xc3\\xa1ra Gotvaldov\\xc3\\xa1, Kate\\xc5\\x99ina H\\xc3\\xa1jkov\\xc3\\xa1, Jan Borovi\\xc4\\x8dka, Radek Jurok, Petra Cihl\\xc3\\xa1\\xc5\\x99ov\\xc3\\xa1, Martin Kucha\\xc5\\x9. Stability of psilocybin and its four analogs in the biomass of the psychotropic mushroom Psilocybe cubensis. Drug testing and analysis. vol 13. issue 2. 2021-10-21. PMID:33119971.' |
psilocybin, psilocin, baeocystin, norbaeocystin, and aeruginascin are tryptamines structurally similar to the neurotransmitter serotonin. |
2021-10-21 |
2023-08-13 |
Not clear |
| Eline Pottie, Annelies Cannaert, Christophe P Stov. In vitro structure-activity relationship determination of 30 psychedelic new psychoactive substances by means of β-arrestin 2 recruitment to the serotonin 2A receptor. Archives of toxicology. vol 94. issue 10. 2021-08-06. PMID:32627074. |
serotonergic psychedelics, substances exerting their effects primarily through the serotonin 2a receptor (5-ht |
2021-08-06 |
2023-08-13 |
Not clear |
| Benjamin Malcolm, Kelan Thoma. Serotonin toxicity of serotonergic psychedelics. Psychopharmacology. 2021-07-12. PMID:34251464. |
serotonin toxicity of serotonergic psychedelics. |
2021-07-12 |
2023-08-13 |
Not clear |
| Eline Pottie, Olga V Kupriyanova, Vadim A Shevyrin, Christophe P Stov. Synthesis and Functional Characterization of 2-(2,5-Dimethoxyphenyl)- ACS chemical neuroscience. vol 12. issue 9. 2021-06-18. PMID:33906351. |
synthesis and functional characterization of 2-(2,5-dimethoxyphenyl)- serotonergic psychedelics, substances exerting their pharmacological action through activation of the serotonin 2a receptor (5-ht |
2021-06-18 |
2023-08-13 |
Not clear |
| Christoph U Correll, Samuele Cortese, Giovanni Croatto, Francesco Monaco, Damir Krinitski, Gonzalo Arrondo, Edoardo G Ostinelli, Caroline Zangani, Michele Fornaro, Andrés Estradé, Paolo Fusar-Poli, Andre F Carvalho, Marco Solm. Efficacy and acceptability of pharmacological, psychosocial, and brain stimulation interventions in children and adolescents with mental disorders: an umbrella review. World psychiatry : official journal of the World Psychiatric Association (WPA). vol 20. issue 2. 2021-05-27. PMID:34002501. |
based on the meta-analytic evidence, the most convincing efficacy profile emerged for amphetamines, methylphenidate and, to a smaller extent, behavioral therapy in attention-deficit/hyperactivity disorder; aripiprazole, risperidone and several psychosocial interventions in autism; risperidone and behavioral interventions in disruptive behavior disorders; several antipsychotics in schizophrenia spectrum disorders; fluoxetine, the combination of fluoxetine and cognitive behavioral therapy (cbt), and interpersonal therapy in depression; aripiprazole in mania; fluoxetine and group cbt in anxiety disorders; fluoxetine/selective serotonin reuptake inhibitors, cbt, and behavioral therapy with exposure and response prevention in obsessive-compulsive disorder; cbt in post-traumatic stress disorder; imipramine and alarm behavioral intervention in enuresis; behavioral therapy in encopresis; and family therapy in anorexia nervosa. |
2021-05-27 |
2023-08-13 |
Not clear |
| Eline Pottie, Olga V Kupriyanova, Asher L Brandt, Robert B Laprairie, Vadim A Shevyrin, Christophe P Stov. Serotonin 2A Receptor (5-HT ACS pharmacology & translational science. vol 4. issue 2. 2021-04-17. PMID:33860178. |
serotonin 2a receptor (5-ht serotonergic psychedelics are defined as compounds having serotonin 2a receptor (5-ht |
2021-04-17 |
2023-08-13 |
Not clear |
| Sara Malaca, Alfredo Fabrizio Lo Faro, Alice Tamborra, Simona Pichini, Francesco Paolo Busardò, Marilyn A Huesti. Toxicology and Analysis of Psychoactive Tryptamines. International journal of molecular sciences. vol 21. issue 23. 2021-03-08. PMID:33291798. |
tryptamines are 5-ht |
2021-03-08 |
2023-08-13 |
Not clear |