| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Vescovo, S M Jones, S E Harding, P A Poole-Wilso. Isoproterenol sensitivity of isolated cardiac myocytes from rats with monocrotaline-induced right-sided hypertrophy and heart failure. Journal of molecular and cellular cardiology. vol 21. issue 10. 1990-01-03. PMID:2555526. |
isoproterenol sensitivity of isolated cardiac myocytes from rats with monocrotaline-induced right-sided hypertrophy and heart failure. |
1990-01-03 |
2023-08-11 |
rat |
| L Hittinger, R P Shannon, S Kohin, A S Lader, W T Manders, T A Patrick, P Kelly, S F Vatne. Isoproterenol-induced alterations in myocardial blood flow, systolic and diastolic function in conscious dogs with heart failure. Circulation. vol 80. issue 3. 1989-10-12. PMID:2527646. |
the effects of isoproterenol were examined in 10 conscious, chronically instrumented adult dogs with left ventricular (lv) failure after pressure overload hypertrophy induced by aortic banding at 8-10 weeks of age (lv free wall plus septum-to-body weight ratio, 8.6 +/- 0.5 g/kg) and also in eight control dogs (lv free wall plus septum-to-body weight ratio, 5.1 +/- 0.3 g/kg). |
1989-10-12 |
2023-08-11 |
Not clear |
| A S Maisel, C Phillips, M C Michel, M G Ziegler, S M Carte. Regulation of cardiac beta-adrenergic receptors by captopril. Implications for congestive heart failure. Circulation. vol 80. issue 3. 1989-10-12. PMID:2548769. |
animals treated with isoproterenol developed cardiac hypertrophy, had increased plasma norepinephrine levels, and had a decreased number and responsiveness of both cardiac and mononuclear leukocyte beta-adrenergic receptors. |
1989-10-12 |
2023-08-11 |
Not clear |
| I J Benjamin, J E Jalil, L B Tan, K Cho, K T Weber, W A Clar. Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. Circulation research. vol 65. issue 3. 1989-10-03. PMID:2527639. |
treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis. |
1989-10-03 |
2023-08-11 |
rat |
| B Chevalier, P Mansier, F Callens-el Amrani, B Swynghedau. Beta-adrenergic system is modified in compensatory pressure cardiac overload in rats: physiological and biochemical evidence. Journal of cardiovascular pharmacology. vol 13. issue 3. 1989-07-17. PMID:2471887. |
the beta-adrenergic system has been explored in cardiac hypertrophy (ch) by combining an in vitro study of the inotropic effect of isoproterenol (iso) and of forskolin (fsk) and binding assays using radioactive pindolol. |
1989-07-17 |
2023-08-11 |
rat |
| J E Jalil, C W Doering, J S Janicki, R Pick, S G Shroff, K T Webe. Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle. Circulation research. vol 64. issue 6. 1989-07-06. PMID:2524288. |
in comparison with controls, we found 1) for a moderate rise in transmural collagen, active and passive stiffness increased with pressure-overload hypertrophy; 2) following isoproterenol alone there was a marked increase in subendocardial collagen, and active and passive stiffness increased; 3) in pressure-overload hypertrophy plus isoproterenol, active stiffness declined. |
1989-07-06 |
2023-08-11 |
rat |
| J E Jalil, C W Doering, J S Janicki, R Pick, S G Shroff, K T Webe. Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle. Circulation research. vol 64. issue 6. 1989-07-06. PMID:2524288. |
passive stiffness was increased except when fibrosis and thinning of the interventricular septum occurred, in which case it decreased; and 4) fibrillar collagens involved in remodeling included the formation of either collagen strands and fibers in a greater number of previously collagen-free intermuscular spaces in pressure-overload hypertrophy, or a dense crisscrossing latticework of fibers that encircled muscle fibers after isoproterenol. |
1989-07-06 |
2023-08-11 |
rat |
| P B Taylor, R K Helbing, S Rourke, D Churchil. Effect of catecholamine-induced cardiac hypertrophy on the force-interval relationship. Canadian journal of physiology and pharmacology. vol 67. issue 1. 1989-06-16. PMID:2523753. |
cardiac hypertrophy was induced in adult female wistar rats following 12 days of daily subcutaneous injections of isoproterenol (iso). |
1989-06-16 |
2023-08-11 |
rat |
| J E Brush, G Eisenhofer, M Garty, R Stull, B J Maron, R O Cannon, J A Panza, S E Epstein, D S Goldstei. Cardiac norepinephrine kinetics in hypertrophic cardiomyopathy. Circulation. vol 79. issue 4. 1989-05-05. PMID:2924414. |
we examined the uptake and release of norepinephrine in the cardiac circulation and other regional vascular beds in 11 patients with hypertrophic cardiomyopathy (hcm) and in 10 control subjects during simultaneous infusion of tracer-labeled norepinephrine and isoproterenol. |
1989-05-05 |
2023-08-11 |
human |
| J E Udelson, R O Cannon, S L Bacharach, T F Rumble, R O Bono. Beta-adrenergic stimulation with isoproterenol enhances left ventricular diastolic performance in hypertrophic cardiomyopathy despite potentiation of myocardial ischemia. Comparison to rapid atrial pacing. Circulation. vol 79. issue 2. 1989-03-15. PMID:2536598. |
beta-adrenergic stimulation with isoproterenol enhances left ventricular diastolic performance in hypertrophic cardiomyopathy despite potentiation of myocardial ischemia. |
1989-03-15 |
2023-08-11 |
Not clear |
| J E Udelson, R O Cannon, S L Bacharach, T F Rumble, R O Bono. Beta-adrenergic stimulation with isoproterenol enhances left ventricular diastolic performance in hypertrophic cardiomyopathy despite potentiation of myocardial ischemia. Comparison to rapid atrial pacing. Circulation. vol 79. issue 2. 1989-03-15. PMID:2536598. |
to determine whether isoproterenol, known to improve relaxation in isolated cardiac muscle, could favorably modify this effect, we assessed simultaneous left ventricular volume and regional systolic asynchrony (by radionuclide angiography), left ventricular pressure (by micromanometer catheters), and lactate metabolism in 12 patients with hypertrophic cardiomyopathy. |
1989-03-15 |
2023-08-11 |
Not clear |
| J E Udelson, R O Cannon, S L Bacharach, T F Rumble, R O Bono. Beta-adrenergic stimulation with isoproterenol enhances left ventricular diastolic performance in hypertrophic cardiomyopathy despite potentiation of myocardial ischemia. Comparison to rapid atrial pacing. Circulation. vol 79. issue 2. 1989-03-15. PMID:2536598. |
although isoproterenol is detrimental in hypertrophic cardiomyopathy by provoking ischemia, these data suggest that the adverse effects of ischemia on ventricular relaxation and distensibility may be alleviated by beta-adrenergic stimulation, possibly as a result of enhanced inactivation and restored load sensitivity. |
1989-03-15 |
2023-08-11 |
Not clear |
| A Grisk, U Hoffmann, K U Mörit. Subacute effects of propranolol and B 24/76 on isoproterenol-induced rat heart hypertrophy in correlation with blood pressure. Biomedica biochimica acta. vol 47. issue 7. 1989-01-26. PMID:2974281. |
thus, the investigations did not provide any evidence that the beta-receptor blockers propranolol and b 24/76 have the potency to prevent isoproterenol from producing heart hypertrophy. |
1989-01-26 |
2023-08-11 |
rat |
| V A Mezl, C Villemure, P M Garber, K Rakusa. Aortic stenosis produces hypertrophy of the rat heart without causing an accumulation of N1-acetylspermidine. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 66. issue 9. 1989-01-12. PMID:2973332. |
isoprenaline treatment causes cardiac hypertrophy and an accumulation of n1-acetylspermidine in the rat heart. |
1989-01-12 |
2023-08-11 |
rat |
| J M Bell, W L Whitmore, T A Slotki. Neonatal nutritional deprivation or enhancement: the cardiac-sympathetic axis and its role in cardiac growth and stress responses. Pediatric research. vol 23. issue 4. 1988-06-30. PMID:3374996. |
nevertheless, cardiac hypertrophy in response to repeated isoproterenol administration was markedly suppressed in nutritionally deprived animals, suggesting that the beta-receptor/ornithine decarboxylase pathway had become uncoupled from growth. |
1988-06-30 |
2023-08-11 |
rat |
| Q Tang, P B Taylor, R K Helbin. Catecholamine induced cardiac hypertrophy. The Canadian journal of cardiology. vol 3. issue 6. 1988-02-26. PMID:2962704. |
cardiac hypertrophy was induced in adult female wistar rats by daily subcutaneous injections of isoproterenol (0.3 mg/kg body weight). |
1988-02-26 |
2023-08-11 |
rat |
| N M Knufman, A van der Laarse, H W Vliegen, C J Brinkma. Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats. Research communications in chemical pathology and pharmacology. vol 57. issue 1. 1987-11-25. PMID:2959998. |
administration of a single high dose or multiple low doses of isoproterenol (iso) to rats induces myocardial necrosis and cardiac hypertrophy. |
1987-11-25 |
2023-08-11 |
rat |
| M G Humphreys-Beher, G D Robinson, S Al-Zahid, C A Schneye. Neural and dietary modulation of proline-rich protein and 4 beta-galactosyltransferase biosynthesis in rat parotid glands. Archives of oral biology. vol 32. issue 8. 1987-11-24. PMID:3118859. |
maintenance of rats on a bulk diet (50 per cent inert cellulose and 50 per cent laboratory chow) before or after the removal of the submandibular-sublingual glands resulted in hypertrophy of the parotid gland, and the induction of basic proline-rich proteins in that gland with apparent molecular weights similar to those found after chronic administration of isoproterenol. |
1987-11-24 |
2023-08-11 |
rat |
| E M Blanchard, L A Mulieri, N R Alper. The effects of acute and chronic inotropic interventions on tension independent heat of rabbit papillary muscle. Basic research in cardiology. vol 82 Suppl 2. 1987-11-19. PMID:2959254. |
contrary to the working hypothesis, positive or negative inotropic effects on twitch tension caused by pressure overload hypertrophy, thyrotoxic hypertrophy, isoproterenol, and udcg115 were not accompanied by parallel changes in tih. |
1987-11-19 |
2023-08-11 |
rabbit |
| A Bergh, H Blom, J E Damber, R Henriksso. The effect of long-term variation in sympathetic activity on testicular morphology in immature rats. Andrologia. vol 19. issue 4. 1987-11-17. PMID:2821845. |
isoproterenol treatment resulted in a marked leydig cell hypertrophy but the development of the spermatogenic epithelium was unaffected compared to that in saline treated controls. |
1987-11-17 |
2023-08-11 |
rat |