| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Helga Höifödt Lidö, Mia Ericson, Hugh Marston, Bo Söderpal. A role for accumbal glycine receptors in modulation of dopamine release by the glycine transporter-1 inhibitor org25935. Frontiers in psychiatry. vol 2. 2011-07-14. PMID:21556278. |
we also addressed whether org25935 and ethanol applied locally in nac interact with dopamine levels, as seen after systemic administration. |
2011-07-14 |
2023-08-12 |
rat |
| Helga Höifödt Lidö, Mia Ericson, Hugh Marston, Bo Söderpal. A role for accumbal glycine receptors in modulation of dopamine release by the glycine transporter-1 inhibitor org25935. Frontiers in psychiatry. vol 2. 2011-07-14. PMID:21556278. |
we used in vivo microdialysis coupled to hplc-ed in freely moving male wistar rats to monitor dopamine output in nac after local perfusion of org25935 alone, with ethanol, or org25935-perfusion after pre-treatment with the glycine receptor antagonist strychnine or the nmda receptor glycine site antagonist l-701.324. |
2011-07-14 |
2023-08-12 |
rat |
| Helga Höifödt Lidö, Mia Ericson, Hugh Marston, Bo Söderpal. A role for accumbal glycine receptors in modulation of dopamine release by the glycine transporter-1 inhibitor org25935. Frontiers in psychiatry. vol 2. 2011-07-14. PMID:21556278. |
ethanol failed to induce a dopamine overflow in the subpopulation responding to org25935 with a dopamine elevation. |
2011-07-14 |
2023-08-12 |
rat |
| Helga Höifödt Lidö, Mia Ericson, Hugh Marston, Bo Söderpal. A role for accumbal glycine receptors in modulation of dopamine release by the glycine transporter-1 inhibitor org25935. Frontiers in psychiatry. vol 2. 2011-07-14. PMID:21556278. |
this adds to the growing evidence for the glycine receptor as an important player in the dopamine reward circuitry and in ethanol's effects within this system. |
2011-07-14 |
2023-08-12 |
rat |
| Simona Perra, Michael A Clements, Brian E Bernier, Hitoshi Morikaw. In vivo ethanol experience increases D(2) autoinhibition in the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 5. 2011-07-13. PMID:21248720. |
although previous in vivo recording studies in rodents have demonstrated profound decreases in the firing activity of ventral tegmental area (vta) dopamine neurons after withdrawal from long-term ethanol exposure, the cellular mechanisms underlying this reduced activity are not well understood. |
2011-07-13 |
2023-08-12 |
mouse |
| Simona Perra, Michael A Clements, Brian E Bernier, Hitoshi Morikaw. In vivo ethanol experience increases D(2) autoinhibition in the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 5. 2011-07-13. PMID:21248720. |
here, by performing patch-clamp recordings from putative dopamine neurons in the vta of mouse brain slices, we show that d(2) receptor/girk-mediated inhibition becomes more potent and exhibits less desensitization after withdrawal from repeated in vivo ethanol exposure (2 g/kg, i.p., three times daily for 7 days). |
2011-07-13 |
2023-08-12 |
mouse |
| Panayotis K Thanos, Vanessa Gopez, Foteini Delis, Michael Michaelides, David K Grandy, Gene-Jack Wang, George Kunos, Nora D Volko. Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. Alcoholism, clinical and experimental research. vol 35. issue 1. 2011-06-23. PMID:20958329. |
upregulation of cannabinoid type 1 receptors in dopamine d2 receptor knockout mice is reversed by chronic forced ethanol consumption. |
2011-06-23 |
2023-08-12 |
mouse |
| Panayotis K Thanos, Vanessa Gopez, Foteini Delis, Michael Michaelides, David K Grandy, Gene-Jack Wang, George Kunos, Nora D Volko. Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. Alcoholism, clinical and experimental research. vol 35. issue 1. 2011-06-23. PMID:20958329. |
the anatomical proximity of the cannabinoid type 1 (cnr1/cb1r) and the dopamine d2 receptors (drd2), their ability to form cb1r-drd2 heteromers, their opposing roles in locomotion, and their involvement in ethanol's reinforcing and addictive properties prompted us to study the levels and distribution of cb1r after chronic ethanol intake, in the presence and absence of drd2. |
2011-06-23 |
2023-08-12 |
mouse |
| Eric C Kong, Katherine Woo, Haiyan Li, Tim Lebestky, Nasima Mayer, Melissa R Sniffen, Ulrike Heberlein, Roland J Bainton, Jay Hirsh, Fred W Wol. A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila. PloS one. vol 5. issue 4. 2011-06-16. PMID:20376353. |
dopamine is a mediator of the stimulant properties of drugs of abuse, including ethanol, in mammals and in the fruit fly drosophila. |
2011-06-16 |
2023-08-12 |
drosophila_melanogaster |
| Eric C Kong, Katherine Woo, Haiyan Li, Tim Lebestky, Nasima Mayer, Melissa R Sniffen, Ulrike Heberlein, Roland J Bainton, Jay Hirsh, Fred W Wol. A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila. PloS one. vol 5. issue 4. 2011-06-16. PMID:20376353. |
we show that a subset of dopamine neurons and their targets, through the action of the d1-like dopamine receptor dopr, promote locomotor activation in response to acute ethanol exposure. |
2011-06-16 |
2023-08-12 |
drosophila_melanogaster |
| Eric C Kong, Katherine Woo, Haiyan Li, Tim Lebestky, Nasima Mayer, Melissa R Sniffen, Ulrike Heberlein, Roland J Bainton, Jay Hirsh, Fred W Wol. A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila. PloS one. vol 5. issue 4. 2011-06-16. PMID:20376353. |
these data tie the activity of defined dopamine neurons to d1-like dopr-expressing neurons to form a neural circuit that governs acute responding to ethanol. |
2011-06-16 |
2023-08-12 |
drosophila_melanogaster |
| Brian E Bernier, Leslie R Whitaker, Hitoshi Morikaw. Previous ethanol experience enhances synaptic plasticity of NMDA receptors in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 14. 2011-06-09. PMID:21471355. |
here, using brain slice electrophysiology in mice, we show that repeated in vivo ethanol exposure (2 g/kg, i.p., three times daily for 7 d) causes increased susceptibility to the induction of long-term potentiation (ltp) of nmda receptor (nmdar)-mediated transmission in mesolimbic dopamine neurons, a form of synaptic plasticity that may drive the learning of stimuli associated with rewards, including drugs of abuse. |
2011-06-09 |
2023-08-12 |
mouse |
| Brian E Bernier, Leslie R Whitaker, Hitoshi Morikaw. Previous ethanol experience enhances synaptic plasticity of NMDA receptors in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 14. 2011-06-09. PMID:21471355. |
these data suggest that repeated ethanol experience may promote the formation of drug-associated memories by enhancing synaptic plasticity of nmdars in dopamine neurons. |
2011-06-09 |
2023-08-12 |
mouse |
| Kelly E Bosse, Tiffany A Mathew. Ethanol-induced increases in extracellular dopamine are blunted in brain-derived neurotrophic factor heterozygous mice. Neuroscience letters. vol 489. issue 3. 2011-04-29. PMID:21163332. |
in the present study, we evaluated the effects of an acute, systemic injection of ethanol (2 g/kg) on bdnf protein levels and extracellular dopamine concentrations, measured by in vivo microdialysis, in the caudate-putamen of wildtype and heterozygous bdnf mice. |
2011-04-29 |
2023-08-12 |
mouse |
| Kelly E Bosse, Tiffany A Mathew. Ethanol-induced increases in extracellular dopamine are blunted in brain-derived neurotrophic factor heterozygous mice. Neuroscience letters. vol 489. issue 3. 2011-04-29. PMID:21163332. |
in both genotypes, the peak increase in extracellular dopamine following ethanol coincided temporally with a decrease in bdnf protein levels following a similar ethanol treatment. |
2011-04-29 |
2023-08-12 |
mouse |
| Kelly E Bosse, Tiffany A Mathew. Ethanol-induced increases in extracellular dopamine are blunted in brain-derived neurotrophic factor heterozygous mice. Neuroscience letters. vol 489. issue 3. 2011-04-29. PMID:21163332. |
moreover, the effect of ethanol to increase extracellular dopamine was blunted in heterozygous bdnf mice compared to wildtype mice. |
2011-04-29 |
2023-08-12 |
mouse |
| Kelly E Bosse, Tiffany A Mathew. Ethanol-induced increases in extracellular dopamine are blunted in brain-derived neurotrophic factor heterozygous mice. Neuroscience letters. vol 489. issue 3. 2011-04-29. PMID:21163332. |
these findings suggest the effects of ethanol are influenced by an interaction between bdnf and dopamine transmission, which may relate to the pathway through which bdnf regulates ethanol intake. |
2011-04-29 |
2023-08-12 |
mouse |
| Louise Adermark, Rhona B C Clarke, Torsten Olsson, Elisabeth Hansson, Bo Söderpalm, Mia Ericso. Implications for glycine receptors and astrocytes in ethanol-induced elevation of dopamine levels in the nucleus accumbens. Addiction biology. vol 16. issue 1. 2011-04-25. PMID:20331561. |
elevated dopamine levels are believed to contribute to the rewarding sensation of ethanol (etoh), and previous research has shown that strychnine-sensitive glycine receptors in the nucleus accumbens (nac) are involved in regulating dopamine release and in mediating the reinforcing effects of etoh. |
2011-04-25 |
2023-08-12 |
rat |
| Priya Mathur, Michael A Berberoglu, Su Gu. Preference for ethanol in zebrafish following a single exposure. Behavioural brain research. vol 217. issue 1. 2011-04-01. PMID:20974186. |
although dopamine is a known component of the reinforcement pathway, clear molecular and cellular compositions of this pathway and its sensitivity to ethanol remain not well understood. |
2011-04-01 |
2023-08-12 |
human |
| Chae Ha Yang, Seong Shoon Yoon, David M Hansen, Jeffrey D Wilcox, Bryan R Blumell, Jung Jae Park, Scott C Steffense. Acupuncture inhibits GABA neuron activity in the ventral tegmental area and reduces ethanol self-administration. Alcoholism, clinical and experimental research. vol 34. issue 12. 2011-03-15. PMID:20860620. |
withdrawal from chronic ethanol enhances ventral tegmental area (vta) gaba neuron excitability and reduces mesolimbic dopamine (da) neurotransmission, which is suppressed by acupuncture at shenmen (ht7) points (zhao et al., 2006). |
2011-03-15 |
2023-08-12 |
Not clear |