| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James M Doherty, Rueben A Gonzale. Lack of effect of nucleus accumbens dopamine D1 receptor blockade on consumption during the first two days of operant self-administration of sweetened ethanol in adult Long-Evans rats. Alcohol (Fayetteville, N.Y.). vol 49. issue 6. 2016-06-22. PMID:26142563. |
lack of effect of nucleus accumbens dopamine d1 receptor blockade on consumption during the first two days of operant self-administration of sweetened ethanol in adult long-evans rats. |
2016-06-22 |
2023-08-13 |
rat |
| James M Doherty, Rueben A Gonzale. Lack of effect of nucleus accumbens dopamine D1 receptor blockade on consumption during the first two days of operant self-administration of sweetened ethanol in adult Long-Evans rats. Alcohol (Fayetteville, N.Y.). vol 49. issue 6. 2016-06-22. PMID:26142563. |
the mechanisms underlying ethanol self-administration are not fully understood; however, it is clear that ethanol self-administration stimulates nucleus accumbens dopamine release in well-trained animals. |
2016-06-22 |
2023-08-13 |
rat |
| James M Doherty, Rueben A Gonzale. Lack of effect of nucleus accumbens dopamine D1 receptor blockade on consumption during the first two days of operant self-administration of sweetened ethanol in adult Long-Evans rats. Alcohol (Fayetteville, N.Y.). vol 49. issue 6. 2016-06-22. PMID:26142563. |
in the present experiment, we test the effects of blockade of nucleus accumbens dopamine d1 receptors on operant sweetened ethanol self-administration behavior during the first 2 days of exposure. |
2016-06-22 |
2023-08-13 |
rat |
| James M Doherty, Rueben A Gonzale. Lack of effect of nucleus accumbens dopamine D1 receptor blockade on consumption during the first two days of operant self-administration of sweetened ethanol in adult Long-Evans rats. Alcohol (Fayetteville, N.Y.). vol 49. issue 6. 2016-06-22. PMID:26142563. |
results show that blocking nucleus accumbens dopamine d1 receptors has little or no influence on consumption during the first 2 days of exposure to the sweetened ethanol solution or maintenance of sucrose-only drinking. |
2016-06-22 |
2023-08-13 |
rat |
| Lucía Martí-Prats, Alejandro Orrico, Ana Polache, Luis Graner. Dual motor responses elicited by ethanol in the posterior VTA: Consequences of the blockade of μ-opioid receptors. Journal of psychopharmacology (Oxford, England). vol 29. issue 9. 2016-06-22. PMID:26216379. |
a recent hypothesis, based on electrophysiological and behavioural findings, suggests that ethanol simultaneously exerts opposed effects on the activity of dopamine (da) neurons in the ventral tegmental area (vta) through two parallel mechanisms, one promoting and the other reducing the gaba release onto vta da neurons. |
2016-06-22 |
2023-08-13 |
rat |
| Andrés Ciudad-Roberts, Leticia Duart-Castells, Jorge Camarasa, David Pubill, Elena Escubed. The combination of ethanol with mephedrone increases the signs of neurotoxicity and impairs neurogenesis and learning in adolescent CD-1 mice. Toxicology and applied pharmacology. vol 293. 2016-06-22. PMID:26747301. |
the combination with ethanol impaired mephedrone-induced decreases in dopamine transporter and tyrosine hydroxylase in the frontal cortex; and in serotonin transporter and tryptophan hydroxylase in the hippocampus by approximately 2-fold, 7days post-treatment. |
2016-06-22 |
2023-08-13 |
mouse |
| Steven Tran, Magda Nowicki, Arrujyan Muraleetharan, Diptendu Chatterjee, Robert Gerla. Differential effects of acute administration of SCH-23390, a D₁ receptor antagonist, and of ethanol on swimming activity, anxiety-related responses, and neurochemistry of zebrafish. Psychopharmacology. vol 232. issue 20. 2016-05-13. PMID:26210378. |
acute exposure to ethanol in zebrafish has been shown to induce a dose-dependent increase of locomotor activity, to reduce fear- and anxiety-related behavioral responses, and to increase the levels of dopamine and its metabolite 3,4-dihydroxyphenylacetic acid (dopac). |
2016-05-13 |
2023-08-13 |
zebrafish |
| Yedy Israel, María Elena Quintanilla, Eduardo Karahanian, Mario Rivera-Meza, Mario Herrera-Marschit. The "first hit" toward alcohol reinforcement: role of ethanol metabolites. Alcoholism, clinical and experimental research. vol 39. issue 5. 2016-04-25. PMID:25828063. |
this review analyzes literature that describes the behavioral effects of 2 metabolites of ethanol (etoh): acetaldehyde and salsolinol (a condensation product of acetaldehyde and dopamine) generated in the brain. |
2016-04-25 |
2023-08-13 |
Not clear |
| Ting Ting Zhao, Keon Sung Shin, Hyun Sook Choi, Myung Koo Le. Ameliorating effects of gypenosides on chronic stress-induced anxiety disorders in mice. BMC complementary and alternative medicine. vol 15. 2016-03-22. PMID:26370834. |
ethanol extract from gynostemma pentaphyllum (gp) shows anti-stress and anxiolytic functions in mice, and also protects dopamine neurons in 6-hydroxydopamine-lesioned rat model of parkinson's disease. |
2016-03-22 |
2023-08-13 |
mouse |
| Clara Pérez-Mañá, Magí Farré, Mitona Pujadas, Cristina Mustata, Esther Menoyo, Antoni Pastor, Klaus Langohr, Rafael de la Torr. Ethanol induces hydroxytyrosol formation in humans. Pharmacological research. vol 95-96. 2016-03-21. PMID:25801942. |
previous studies in animals have shown an increase of hydroxytyrosol (ohtyr), a potent phenolic antioxidant and a minor metabolite of dopamine (also called 3,4-dihydroxyphenylethanol or dopet), after ethanol intake. |
2016-03-21 |
2023-08-13 |
human |
| Clara Pérez-Mañá, Magí Farré, Mitona Pujadas, Cristina Mustata, Esther Menoyo, Antoni Pastor, Klaus Langohr, Rafael de la Torr. Ethanol induces hydroxytyrosol formation in humans. Pharmacological research. vol 95-96. 2016-03-21. PMID:25801942. |
the interaction between ethanol and dopamine metabolism is the probable mechanism involved. |
2016-03-21 |
2023-08-13 |
human |
| Paul W Czot. Effects of chronic binge-like ethanol consumption on cocaine self-administration in rhesus monkeys. Drug and alcohol dependence. vol 153. 2016-03-02. PMID:26048636. |
these experiments in rhesus monkeys determined the effects of >8 weeks of ethanol (etoh) consumption on cocaine self-administration (n=6), effects of dopamine (da) receptor antagonists on cocaine reinforcement (n=3-4 per drug) and the ability of the d2-like da receptor agonist quinpirole to elicit yawning (n=3). |
2016-03-02 |
2023-08-13 |
monkey |
| Onarae V Rice, Charles A Schonhar, J Gaál, Eliot L Gardner, Charles R Ashb. The selective dopamine D₃ receptor antagonist SB-277011-A significantly decreases binge-like consumption of ethanol in C57BL/J6 mice. Synapse (New York, N.Y.). vol 69. issue 6. 2016-01-13. PMID:25764479. |
the selective dopamine d₃ receptor antagonist sb-277011-a significantly decreases binge-like consumption of ethanol in c57bl/j6 mice. |
2016-01-13 |
2023-08-13 |
mouse |
| R J Ward, J Mccradden, K Tipton, R Sherwood, J Keating, T J Peters, P DE Witt. Biochemical and genetic studies of Caucasian subjects with ethanol-induced flushing reaction. Addiction biology. vol 3. issue 4. 2016-01-08. PMID:26735122. |
(1) since the principal role of this cytosolic enzyme may be in the metabolism of biogenic amines, serotonin levels in platelet-rich plasma and urinary adrenaline, noradrenaline and dopamine were assayed in affected individuals after an oral ethanol challenge. |
2016-01-08 |
2023-08-13 |
human |
| Kathryn Hausknecht, Samir Haj-Dahmane, Ying-Ling Shen, Paul Vezina, Cynthia Dlugos, Roh-Yu She. Excitatory synaptic function and plasticity is persistently altered in ventral tegmental area dopamine neurons after prenatal ethanol exposure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25284318. |
excitatory synaptic function and plasticity is persistently altered in ventral tegmental area dopamine neurons after prenatal ethanol exposure. |
2016-01-05 |
2023-08-13 |
rat |
| Zheng-Ming Ding, Cynthia M Ingraham, Zachary A Rodd, William J McBrid. The reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24674134. |
the reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems. |
2016-01-01 |
2023-08-12 |
Not clear |
| Zheng-Ming Ding, Cynthia M Ingraham, Zachary A Rodd, William J McBrid. The reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24674134. |
ethanol can be self-infused directly into the posterior ventral tegmental area (pvta) and these effects involve activation of local dopamine neurons. |
2016-01-01 |
2023-08-12 |
Not clear |
| Zheng-Ming Ding, Cynthia M Ingraham, Zachary A Rodd, William J McBrid. The reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24674134. |
intra-pvta microinjection of ethanol increases dopamine release in the nucleus accumbens (nac), medial prefrontal cortex (mpfc) and ventral pallidum (vp). |
2016-01-01 |
2023-08-12 |
Not clear |
| Zheng-Ming Ding, Cynthia M Ingraham, Zachary A Rodd, William J McBrid. The reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24674134. |
the present study tested the hypothesis that the reinforcing effects of ethanol within the pvta involve the activation of dopamine projections from the pvta to the nac, vp and mpfc. |
2016-01-01 |
2023-08-12 |
Not clear |
| Zheng-Ming Ding, Cynthia M Ingraham, Zachary A Rodd, William J McBrid. The reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24674134. |
following the acquisition of self-infusions of 200 mg% ethanol into the pvta, either the dopamine d2 receptor antagonist sulpiride (0, 10 or 100 μm) or the d1 receptor antagonist sch-23390 (0, 10 or 100 μm) was microinjected into the ipsilateral nac shell (nacsh), nac core (naccr), vp or mpfc immediately prior to the self-infusion sessions to assess the involvement of the different dopamine projections in the reinforcing effects of ethanol. |
2016-01-01 |
2023-08-12 |
Not clear |