| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anushree N Karkhanis, Kimberly N Huggins, Jamie H Rose, Sara R Jone. Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27450094. |
switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: role of kappa opioid receptors. |
2017-07-10 |
2023-08-13 |
mouse |
| Anushree N Karkhanis, Kimberly N Huggins, Jamie H Rose, Sara R Jone. Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27450094. |
this study aimed to examine the effects of kor modulation on dopamine responses to ethanol of behaving mice exposed to air or ethanol vapor in a repeated intermittent pattern. |
2017-07-10 |
2023-08-13 |
mouse |
| Anushree N Karkhanis, Kimberly N Huggins, Jamie H Rose, Sara R Jone. Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27450094. |
second, using in vivo microdialysis, we showed that, in contrast to the expected increase in extracellular levels of dopamine following an acute ethanol challenge in air exposed mice, cie exposed mice exhibited a robust decrease in dopamine levels. |
2017-07-10 |
2023-08-13 |
mouse |
| Anushree N Karkhanis, Kimberly N Huggins, Jamie H Rose, Sara R Jone. Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27450094. |
third, we showed that blockade of kors reversed the aberrant inhibitory dopamine response to ethanol in cie exposed mice while not affecting the air exposed mice demonstrating that inhibition of kors "rescued" dopamine responses in cie exposed mice. |
2017-07-10 |
2023-08-13 |
mouse |
| Anushree N Karkhanis, Kimberly N Huggins, Jamie H Rose, Sara R Jone. Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27450094. |
taken together, these findings indicate that augmentation of dynorphin/kor system activity drives the reduction in stimulated (electrical and ethanol) dopamine release in the nac. |
2017-07-10 |
2023-08-13 |
mouse |
| Zheng-Ming Ding, Cynthia M Ingraham, Zachary A Rodd, William J McBrid. Alcohol drinking increases the dopamine-stimulating effects of ethanol and reduces D2 auto-receptor and group II metabotropic glutamate receptor function within the posterior ventral tegmental area of alcohol preferring (P) rats. Neuropharmacology. vol 109. 2017-06-19. PMID:27260326. |
repeated local administration of ethanol (etoh) sensitized the posterior ventral tegmental area (pvta) to the local dopamine (da)-stimulating effects of etoh. |
2017-06-19 |
2023-08-13 |
rat |
| Jamie H Rose, Anushree N Karkhanis, Björn Steiniger-Brach, Sara R Jone. Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure. International journal of molecular sciences. vol 17. issue 8. 2017-03-28. PMID:27472317. |
distinct effects of nalmefene on dopamine uptake rates and kappa opioid receptor activity in the nucleus accumbens following chronic intermittent ethanol exposure. |
2017-03-28 |
2023-08-13 |
mouse |
| Jamie H Rose, Anushree N Karkhanis, Björn Steiniger-Brach, Sara R Jone. Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure. International journal of molecular sciences. vol 17. issue 8. 2017-03-28. PMID:27472317. |
it is possible that nalmefene may attenuate withdrawal-induced increases in ethanol consumption by modulation of dopamine transmission through kors. |
2017-03-28 |
2023-08-13 |
mouse |
| Gerald A Deehan, Christopher P Knight, R Aaron Waeiss, Eric A Engleman, Jamie E Toalston, William J McBride, Sheketha R Hauser, Zachary A Rod. Peripheral Administration of Ethanol Results in a Correlated Increase in Dopamine and Serotonin Within the Posterior Ventral Tegmental Area. Alcohol and alcoholism (Oxford, Oxfordshire). vol 51. issue 5. 2017-01-24. PMID:27307055. |
peripheral administration of ethanol results in a correlated increase in dopamine and serotonin within the posterior ventral tegmental area. |
2017-01-24 |
2023-08-13 |
Not clear |
| Gerald A Deehan, Christopher P Knight, R Aaron Waeiss, Eric A Engleman, Jamie E Toalston, William J McBride, Sheketha R Hauser, Zachary A Rod. Peripheral Administration of Ethanol Results in a Correlated Increase in Dopamine and Serotonin Within the Posterior Ventral Tegmental Area. Alcohol and alcoholism (Oxford, Oxfordshire). vol 51. issue 5. 2017-01-24. PMID:27307055. |
two critical neurotransmitter systems regulating ethanol (etoh) reward are serotonin (5-ht) and dopamine (da). |
2017-01-24 |
2023-08-13 |
Not clear |
| David R Spiegel, Aidan McCroskey, Kapaakea Puaa, Grant Meeker, Lauren Hartman, Joshua Hudson, Yu C Hun. A Case of Disulfiram-Induced Psychosis in a Previously Asymptomatic Patient Maintained on Mixed Amphetamine Salts: A Review of the Literature and Possible Pathophysiological Explanations. Clinical neuropharmacology. vol 39. issue 5. 2017-01-20. PMID:27466724. |
although perhaps better known as an irreversible aldehyde dehydrogenase inhibitor causing increased acetaldehyde levels after concomitant intake of ethanol, disulfiram or one of its metabolites (diethyldithiocarbamate) also inhibit dopamine β-hydroxylase, an enzyme that converts dopamine to norepinephrine. |
2017-01-20 |
2023-08-13 |
Not clear |
| Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin, Etienne Quertemon. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25545401. |
correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. |
2016-12-20 |
2023-08-13 |
mouse |
| Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin, Etienne Quertemon. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25545401. |
some recent results argue against a role for ventral tegmental area (vta) dopamine neurons in ethanol behavioral sensitization. |
2016-12-20 |
2023-08-13 |
mouse |
| Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin, Etienne Quertemon. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25545401. |
the aim of the present study was to test whether in vivo ethanol locomotor sensitization correlates with changes in either basal- or ethanol-evoked firing rates of dopamine neurons in vitro. |
2016-12-20 |
2023-08-13 |
mouse |
| Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin, Etienne Quertemon. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25545401. |
this shows that the d2 feedback in dopamine neurons is preserved after chronic ethanol administration and argues against a reduced d2 feedback as an explanation for the increased dopamine neuron basal firing rates in ethanol-sensitized mice. |
2016-12-20 |
2023-08-13 |
mouse |
| Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin, Etienne Quertemon. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25545401. |
finally, ethanol superfusion (10-100 mm) significantly increased the firing rates of dopamine neurons and this effect was of higher magnitude in ethanol-sensitized mice. |
2016-12-20 |
2023-08-13 |
mouse |
| Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin, Etienne Quertemon. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25545401. |
furthermore, there were significant correlations between such a sensitization of dopamine neuron activity and ethanol behavioral sensitization. |
2016-12-20 |
2023-08-13 |
mouse |
| Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin, Etienne Quertemon. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25545401. |
these results support the hypothesis that changes in brain dopamine neuron activity contribute to the behavioral sensitization of the stimulant effects of ethanol. |
2016-12-20 |
2023-08-13 |
mouse |
| Gessynger Morais-Silva, Mariane Ferreira-Santos, Marcelo T Mari. Conessine, an H3 receptor antagonist, alters behavioral and neurochemical effects of ethanol in mice. Behavioural brain research. vol 305. 2016-12-16. PMID:26924015. |
aiming to understand these interactions, conessine, an h3 receptor antagonist, was given to mice subjected to the evaluation of ethanol-induced psychostimulation, ethanol cpp and quantification of norepinephrine, dopamine, serotonin and their metabolites in mesocorticolimbic and nigrostriatal pathways following acute ethanol treatment. |
2016-12-16 |
2023-08-13 |
mouse |
| Gessynger Morais-Silva, Mariane Ferreira-Santos, Marcelo T Mari. Conessine, an H3 receptor antagonist, alters behavioral and neurochemical effects of ethanol in mice. Behavioural brain research. vol 305. 2016-12-16. PMID:26924015. |
the blockade of h3 receptors and ethanol seem to interact in the modulation of dopaminergic neurotransmission of nigrostriatal pathway, decreasing dopamine metabolites in substantia nigra. |
2016-12-16 |
2023-08-13 |
mouse |