| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lin Zhou, Jinhua Zhou, Bin Sheng, Xin Li, Youchao Yua. Dexmedetomidine exerts dual effects on human annulus fibrosus chondrocytes depending on the oxidative stress status. Bioscience reports. vol 39. issue 8. 2020-09-09. PMID:31383789. |
dexmedetomidine (dex) is an anesthetic widely used in lumbar discectomy, but its effect on chondrocytes remains unclear. |
2020-09-09 |
2023-08-13 |
human |
| Jing Li, Jun-Song Yang, Bu-Huai Dong, Jiu-Min Y. The Effect of Dexmedetomidine Added to Preemptive Ropivacaine Infiltration on Postoperative Pain After Lumbar Fusion Surgery: A Randomized Controlled Trial. Spine. vol 44. issue 19. 2019-12-30. PMID:31095117. |
the effect of dexmedetomidine added to preemptive ropivacaine infiltration on postoperative pain after lumbar fusion surgery: a randomized controlled trial. |
2019-12-30 |
2023-08-13 |
Not clear |
| Jing Li, Jun-Song Yang, Bu-Huai Dong, Jiu-Min Y. The Effect of Dexmedetomidine Added to Preemptive Ropivacaine Infiltration on Postoperative Pain After Lumbar Fusion Surgery: A Randomized Controlled Trial. Spine. vol 44. issue 19. 2019-12-30. PMID:31095117. |
a prospective and controlled study of dexmedetomidine added to preemptive ropivacaine infiltration in lumbar fusion surgery. |
2019-12-30 |
2023-08-13 |
Not clear |
| V A Byvaltsev, V Y Goloborod'ko, A A Kalinin, A K Okoneshnikova, M V Strelko. [Analysis of the effectiveness of Dexmedetomidine in the treatment of degenerative diseases of the lumbar spine with minimally invasive puncture techniques in elderly patients.] Advances in gerontology = Uspekhi gerontologii. vol 31. issue 3. 2019-06-11. PMID:30584882. |
[analysis of the effectiveness of dexmedetomidine in the treatment of degenerative diseases of the lumbar spine with minimally invasive puncture techniques in elderly patients.] |
2019-06-11 |
2023-08-13 |
Not clear |
| V A Byvaltsev, V Y Goloborod'ko, A A Kalinin, A K Okoneshnikova, M V Strelko. [Analysis of the effectiveness of Dexmedetomidine in the treatment of degenerative diseases of the lumbar spine with minimally invasive puncture techniques in elderly patients.] Advances in gerontology = Uspekhi gerontologii. vol 31. issue 3. 2019-06-11. PMID:30584882. |
the aim of the study was a comparative analysis of the effectiveness of the use of dexmedetomidine and propofol in the treatment of degenerative diseases of the lumbar spine with minimally invasive puncture techniques in elderly patients. |
2019-06-11 |
2023-08-13 |
Not clear |
| Youngsuk Kwon, Ji Su Jang, Sung Mi Hwang, Jae Jun Lee, Hyonjin Tar. Intraoperative administration of dexmedetomidine reduced the postoperative catheter-related bladder discomfort and pain in patients undergoing lumbar microdiscectomy. Journal of anesthesia. vol 32. issue 1. 2019-04-22. PMID:29098393. |
intraoperative administration of dexmedetomidine reduced the postoperative catheter-related bladder discomfort and pain in patients undergoing lumbar microdiscectomy. |
2019-04-22 |
2023-08-13 |
Not clear |
| Marion Wiegele, Peter Marhofer, Per-Arne Lönnqvis. Caudal epidural blocks in paediatric patients: a review and practical considerations. British journal of anaesthesia. vol 122. issue 4. 2019-04-22. PMID:30857607. |
this narrative review discusses the main findings in the current literature with regard to patient selection (sub-umbilical vs mid-abdominal indications, contraindications, low-risk patients with spinal anomalies); anatomical considerations (access problems, age and body positioning, palpation for needle insertion); technical considerations (verification of needle position by ultrasound vs landmarks vs 'whoosh' or 'swoosh' testing); training and equipment requirements (learning curve, needle types, risk of tissue spreading); complications and safety (paediatric regional anaesthesia, caudal blocks); local anaesthetics (bupivacaine vs ropivacaine, risk of toxicity in children, management of toxic events); adjuvant drugs (clonidine, dexmedetomidine, opioids, ketamine); volume dosing (dermatomal reach, cranial rebound); caudally accessed lumbar or thoracic anaesthesia (contamination risk, verifying catheter placement); and postoperative pain. |
2019-04-22 |
2023-08-13 |
Not clear |
| Saikat Mitra, Shobha Purohit, Mamta Sharm. Postoperative Analgesia After Wound Infiltration With Tramadol and Dexmedetomidine as an Adjuvant to Ropivacaine for Lumbar Discectomies: A Randomized-controlled Clinical Trial. Journal of neurosurgical anesthesiology. vol 29. issue 4. 2018-05-30. PMID:28266950. |
postoperative analgesia after wound infiltration with tramadol and dexmedetomidine as an adjuvant to ropivacaine for lumbar discectomies: a randomized-controlled clinical trial. |
2018-05-30 |
2023-08-13 |
Not clear |
| Saikat Mitra, Shobha Purohit, Mamta Sharm. Postoperative Analgesia After Wound Infiltration With Tramadol and Dexmedetomidine as an Adjuvant to Ropivacaine for Lumbar Discectomies: A Randomized-controlled Clinical Trial. Journal of neurosurgical anesthesiology. vol 29. issue 4. 2018-05-30. PMID:28266950. |
the aim of this trial was to evaluate the analgesic efficacy of tramadol and dexmedetomidine when added to ropivacaine for wound infiltration in lumbar discectomies. |
2018-05-30 |
2023-08-13 |
Not clear |
| Ashraf Eskandr, Sadik Abdel Masee. The Effect of Dexmedetomidine on Lumbar Epidural Injection for Failed Back Surgery Syndrome. Anesthesiology research and practice. vol 2016. 2016-09-16. PMID:27630712. |
the effect of dexmedetomidine on lumbar epidural injection for failed back surgery syndrome. |
2016-09-16 |
2023-08-13 |
Not clear |
| Ashraf Eskandr, Sadik Abdel Masee. The Effect of Dexmedetomidine on Lumbar Epidural Injection for Failed Back Surgery Syndrome. Anesthesiology research and practice. vol 2016. 2016-09-16. PMID:27630712. |
this study evaluates the effect of adding dexmedetomidine to lumbar epidural steroids in patients with failed back surgery syndrome. |
2016-09-16 |
2023-08-13 |
Not clear |
| Chun-Guang Wang, Yan-Ling Ding, Ai-Ping Han, Chang-Qing Hu, Shi Hao, Fang-Fang Zhang, Yong-Wang Li, Hu Liu, Zhe Han, De-Li Guo, Zhi-Qiang Zhan. Adding dexmedetomidine to ropivacaine for lumbar plexus and sciatic nerve block for amputation of lower limb in high-risk patient-a case report. International journal of clinical and experimental medicine. vol 8. issue 8. 2015-11-09. PMID:26550393. |
adding dexmedetomidine to ropivacaine for lumbar plexus and sciatic nerve block for amputation of lower limb in high-risk patient-a case report. |
2015-11-09 |
2023-08-13 |
Not clear |
| Chun-Guang Wang, Yan-Ling Ding, Ai-Ping Han, Chang-Qing Hu, Shi Hao, Fang-Fang Zhang, Yong-Wang Li, Hu Liu, Zhe Han, De-Li Guo, Zhi-Qiang Zhan. Adding dexmedetomidine to ropivacaine for lumbar plexus and sciatic nerve block for amputation of lower limb in high-risk patient-a case report. International journal of clinical and experimental medicine. vol 8. issue 8. 2015-11-09. PMID:26550393. |
dexmedetomidine 1 μg/kg was added to 0.33% ropivacaine for lumbar plexus and sciatic nerve block in this case for intra-operative anesthesia and post-operative analgesia. |
2015-11-09 |
2023-08-13 |
Not clear |
| Chun-Guang Wang, Yan-Ling Ding, Ai-Ping Han, Chang-Qing Hu, Shi Hao, Fang-Fang Zhang, Yong-Wang Li, Hu Liu, Zhe Han, De-Li Guo, Zhi-Qiang Zhan. Adding dexmedetomidine to ropivacaine for lumbar plexus and sciatic nerve block for amputation of lower limb in high-risk patient-a case report. International journal of clinical and experimental medicine. vol 8. issue 8. 2015-11-09. PMID:26550393. |
this case showed that adding 1 μg/kg dexmedetomidine to ropivacaine for lumbar plexus and sciatic nerve block may be a feasible and safe technique for high-risk patients for lower limb surgery of amputation. |
2015-11-09 |
2023-08-13 |
Not clear |
| Kyung Hoon Ki. Safe Sedation and Hypnosis using Dexmedetomidine for Minimally Invasive Spine Surgery in a Prone Position. The Korean journal of pain. vol 27. issue 4. 2014-10-15. PMID:25317279. |
the great merit of dexmedetomidine for cs or mac is the ability of the operator to recognize nerve damage during percutaneous endoscopic lumbar discectomy, a representative miss. |
2014-10-15 |
2023-08-13 |
Not clear |
| Shuang-Shuang Li, Wei-Shi Zhang, Dong Ji, Ya-Lan Zhou, Hui Li, Jia-Le Yang, Yuan-Chang Xiong, Yu-Qiu Zhang, Hua X. Involvement of spinal microglia and interleukin-18 in the anti-nociceptive effect of dexmedetomidine in rats subjected to CCI. Neuroscience letters. vol 560. 2014-09-08. PMID:24345418. |
western blotting revealed that dexmedetomidine reduced the activation of microglia and the upregulation of interleukin-18 (il-18) protein expression in the ipsilateral lumbar spinal dorsal horn, while brl44408 pretreatment significantly blocked these effects of dexmedetomidine. |
2014-09-08 |
2023-08-12 |
rat |
| Jennifer E Carter, Crace Lewis, Thierry Beth. Onset and quality of sedation after intramuscular administration of dexmedetomidine and hydromorphone in various muscle groups in dogs. Journal of the American Veterinary Medical Association. vol 243. issue 11. 2014-07-21. PMID:24261806. |
to compare onset time and quality of sedation achieved by im injection of hydromorphone and dexmedetomidine into either the semimembranosus, cervical, gluteal, or lumbar muscle groups in dogs. |
2014-07-21 |
2023-08-12 |
Not clear |
| Masafumi Kimura, Shigeru Saito, Hideaki Obat. Dexmedetomidine decreases hyperalgesia in neuropathic pain by increasing acetylcholine in the spinal cord. Neuroscience letters. vol 529. issue 1. 2013-04-05. PMID:22917606. |
in vivo microdialysis in the lumbar spinal dorsal horn revealed that acetylcholine concentrations increased after dexmedetomidine perfusion (1 μm), but only in snl rats. |
2013-04-05 |
2023-08-12 |
rat |
| Bo Xu, Wei-Shi Zhang, Jia-Le Yang, Ning Lû, Xiao-Ming Deng, Hua Xu, Yu-Qiu Zhan. Evidence for suppression of spinal glial activation by dexmedetomidine in a rat model of monoarthritis. Clinical and experimental pharmacology & physiology. vol 37. issue 10. 2011-09-02. PMID:20626414. |
repeated lumbar puncture (lp) administration of dexmedetomidine (10 μg) significantly attenuated ma-induced thermal hyperalgesia in a cumulative manner. |
2011-09-02 |
2023-08-12 |
rat |
| Janette D McVey, Joseph D Tobia. Dexmedetomidine and ketamine for sedation during spinal anesthesia in children. Journal of clinical anesthesia. vol 22. issue 7. 2011-02-22. PMID:21056811. |
to evaluate the combination of dexmedetomidine and ketamine for sedation during lumbar puncture and sedation for spinal anesthesia in children. |
2011-02-22 |
2023-08-12 |
Not clear |