| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Swarup Mitra, Pedro H Gobira, Craig T Werner, Jennifer A Martin, Madoka Iida, Shruthi A Thomas, Kyra Erias, Sophia Miracle, Charles Lafargue, Chunna An, David M Diet. A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue-induced cocaine craving following prolonged abstinence. Addiction biology. vol 26. issue 5. 2021-10-06. PMID:33496035. |
at prolonged abstinence (30 days) from cocaine self-administration, there is an increase in the nac levels of diacylglycerol lipase (dagl), the enzyme responsible for the synthesis of the endocannabinoid 2-ag, along with decreased levels of monoacylglycerol lipase (magl), which hydrolyzes 2-ag. |
2021-10-06 |
2023-08-13 |
Not clear |
| Dimitri Daldegan-Bueno, Lucas O Maia, Michelle Glass, Didier Jutras-Aswad, Benedikt Fische. Co-exposure of cocaine and cannabinoids and its association with select biological, behavioural and health outcomes: A systematic scoping review of multi-disciplinary studies. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 51. 2021-10-01. PMID:34273801. |
co-exposure of cocaine and cannabinoids and its association with select biological, behavioural and health outcomes: a systematic scoping review of multi-disciplinary studies. |
2021-10-01 |
2023-08-13 |
human |
| Dimitri Daldegan-Bueno, Lucas O Maia, Michelle Glass, Didier Jutras-Aswad, Benedikt Fische. Co-exposure of cocaine and cannabinoids and its association with select biological, behavioural and health outcomes: A systematic scoping review of multi-disciplinary studies. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 51. 2021-10-01. PMID:34273801. |
benefits of cannabinoids for addiction have been documented, making it opportune to examine existing data on the possible outcomes associated with cannabinoids and cocaine co-use. |
2021-10-01 |
2023-08-13 |
human |
| Dimitri Daldegan-Bueno, Lucas O Maia, Michelle Glass, Didier Jutras-Aswad, Benedikt Fische. Co-exposure of cocaine and cannabinoids and its association with select biological, behavioural and health outcomes: A systematic scoping review of multi-disciplinary studies. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 51. 2021-10-01. PMID:34273801. |
while pre-clinical studies suggest a potential of cannabinoids, especially cbd, to treat cocaine addiction, the few trials conducted in humans found no benefits. |
2021-10-01 |
2023-08-13 |
human |
| Timothy B Erickson, Noriko Endo, Claire Duvallet, Newsha Ghaeli, Kaitlyn Hess, Eric J Alm, Mariana Matus, Peter R Cha. "Waste Not, Want Not" - Leveraging Sewer Systems and Wastewater-Based Epidemiology for Drug Use Trends and Pharmaceutical Monitoring. Journal of medical toxicology : official journal of the American College of Medical Toxicology. vol 17. issue 4. 2021-09-30. PMID:34402038. |
applications of wbe include monitoring policy changes with cannabinoid legalization, tracking emerging illicit drugs, and early warning systems for potent fentanyl analogues along with the resurging wave of stimulants (e.g., methamphetamine, cocaine). |
2021-09-30 |
2023-08-13 |
Not clear |
| Elba Arango, Allison Toriello, Zoila Rosario, Gail Coope. Increasing Prevalence of Ketamine in Drivers in New York City Including the Identification of 2-Fluoro-Deschloroketamine. Journal of analytical toxicology. vol 45. issue 8. 2021-09-20. PMID:34050644. |
the most common drug classes detected in addition to ketamine were cannabinoids (38%), ethanol (32%), benzodiazepines (26%), cocaine (19%) and amphetamines/3,4-methylenedioxymethamphetamine (15%). |
2021-09-20 |
2023-08-13 |
human |
| T Franz, G Skopp, F Mußhof. Findings of illicit drugs in hair of children at different ages. International journal of legal medicine. vol 135. issue 2. 2021-09-09. PMID:33392654. |
all drugs under investigation such as cannabinoids, cocaine, amphetamines, and opiates have been detected in breast milk as well as in skin excretions such as sebum, sweat and cutaneous cells. |
2021-09-09 |
2023-08-13 |
Not clear |
| T Franz, G Skopp, F Mußhof. Findings of illicit drugs in hair of children at different ages. International journal of legal medicine. vol 135. issue 2. 2021-09-09. PMID:33392654. |
interestingly, the increase of cannabinoids, cocaine, and amphetamines concentrations in adolescents' hair points to a deliberate use of these drugs possibly in addition to passive exposure. |
2021-09-09 |
2023-08-13 |
Not clear |
| So Yeon Lee, Sang Tak Lee, Sungill Suh, Bum Jun Ko, Han Bin O. Revealing Unknown Controlled Substances and New Psychoactive Substances Using High-Resolution LC-MS/MS Machine Learning Models and the Hybrid Similarity Search Algorithm. Journal of analytical toxicology. 2021-09-09. PMID:34498039. |
in these models, controlled substances and nps's were classified into 13 subgroups (benzylpiperazine, opiate, benzodiazepine, amphetamine, cocaine, methcathinone, classical cannabinoid, fentanyl, 2c series, indazole carbonyl compound, indole carbonyl compound, phencyclidine, and others). |
2021-09-09 |
2023-08-13 |
Not clear |
| Javier Orihuel, Laura Gómez-Rubio, Claudia Valverde, Roberto Capellán, David Roura-Martínez, Marcos Ucha, Emilio Ambrosio, Alejandro Higuera-Mata. Cocaine-induced Fos expression in the rat brain: Modulation by prior Δ Brain research. vol 1764. 2021-08-25. PMID:33861997. |
indeed, previous preclinical data show that adolescent exposure to cannabinoids (both natural and synthetic) potentiates cocaine self-administration in rats. |
2021-08-25 |
2023-08-13 |
rat |
| Javier Orihuel, Laura Gómez-Rubio, Claudia Valverde, Roberto Capellán, David Roura-Martínez, Marcos Ucha, Emilio Ambrosio, Alejandro Higuera-Mata. Cocaine-induced Fos expression in the rat brain: Modulation by prior Δ Brain research. vol 1764. 2021-08-25. PMID:33861997. |
these results add to the previous literature suggesting that the behavioral, cellular, molecular, and brain-activating actions of cocaine are modulated by early experience with cannabinoids and provide additional knowledge that may explain the enhanced actions of cocaine in rats exposed to cannabinoids during their adolescence. |
2021-08-25 |
2023-08-13 |
rat |
| Aaron Caccamise, Erik Van Newenhizen, John R Mantsc. Neurochemical mechanisms and neurocircuitry underlying the contribution of stress to cocaine seeking. Journal of neurochemistry. vol 157. issue 5. 2021-08-24. PMID:33660857. |
in the prelimbic cortex, corticosterone mobilizes the endocannabinoid, 2-arachidonoylglycerol (2-ag), which produces cb1 receptor-dependent reductions in inhibitory transmission, thereby increasing excitability of neurons which comprise output pathways responsible for cocaine seeking. |
2021-08-24 |
2023-08-13 |
Not clear |
| Hamed Salmanzadeh, S Mohammad Ahmadi-Soleimani, Narges Pachenari, Maryam Azadi, Robert F Halliwell, Tiziana Rubino, Hossein Aziz. Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function. Brain research bulletin. vol 156. 2021-08-20. PMID:31926303. |
these studies on adolescent exposure to alcohol, nicotine, opioids, cannabinoids and psychostimulant drugs, such as cocaine and amphetamine, reveal a variety of long-lasting behavioral and neurobiological consequences. |
2021-08-20 |
2023-08-13 |
Not clear |
| Sheila A Engi, Erin J Beebe, Victoria M Ayvazian, Fabio C Cruz, Joseph F Cheer, Jennifer M Wenzel, Natalie E Zlebni. Cocaine-induced increases in motivation require 2-arachidonoylglycerol mobilization and CB1 receptor activation in the ventral tegmental area. Neuropharmacology. vol 193. 2021-07-28. PMID:34058192. |
recent findings demonstrate that cocaine mobilizes the endocannabinoid 2-arachidonoylglycerol (2-ag) in the vta to cause phasic activation of da neurons and terminal da release. |
2021-07-28 |
2023-08-13 |
rat |
| Hai-Ying Zhang, Lindsay De Biase, Ramesh Chandra, Hui Shen, Qing-Rong Liu, Eliot Gardner, Mary Kay Lobo, Zheng-Xiong X. Repeated cocaine administration upregulates CB Acta pharmacologica Sinica. 2021-07-28. PMID:34316031. |
repeated cocaine administration upregulates cb cannabinoid cb |
2021-07-28 |
2023-08-13 |
Not clear |
| Andrea D Clements, Natalie A Cypher. Prenatal substance use: Religious women report lower use rates, but do they use less? Journal of prevention & intervention in the community. vol 48. issue 1. 2021-07-12. PMID:31132947. |
self-reported use and toxicology screening results taken from a larger prospective, longitudinal, smoking cessation study were compared for five substances (cannabinoids [marijuana or other cannabinoids], benz/barb/sed [including benzodiazepines, barbiturates, or any sedative], opioids [including heroin, methadone or other medication-assisted treatment medications, or other opiates], crack/cocaine [crack or cocaine], and meth/amph [including methamphetamine or any other amphetamine]). |
2021-07-12 |
2023-08-13 |
Not clear |
| Joseph Mansour, Maria Zulfiqar, Affan Umer, Kenneth S Zurcher, Allen Heeger, Christine O Menia. Abdominal Imaging Manifestations of Recreational Drug Use. Radiographics : a review publication of the Radiological Society of North America, Inc. vol 40. issue 7. 2021-07-12. PMID:33064622. |
the most commonly used drugs worldwide include cocaine, cannabinoids, opioids, and amphetamines and their derivatives. |
2021-07-12 |
2023-08-13 |
Not clear |
| Agustin Zapata, Carl R Lupic. Lateral habenula cannabinoid CB1 receptor involvement in drug-associated impulsive behavior. Neuropharmacology. vol 192. 2021-07-12. PMID:33965396. |
however, the brain areas where cannabinoids might control impulsivity or cocaine seeking are largely unknown. |
2021-07-12 |
2023-08-13 |
human |
| Radhouene Doggui, Wafaa Elsawy, Aldo Alberto Conti, Alex Baldacchin. Association between chronic psychoactive substances use and systemic inflammation: A systematic review and meta-analysis. Neuroscience and biobehavioral reviews. vol 125. 2021-06-28. PMID:33639179. |
to meet the required inclusion criteria, all studies had to describe human participants with an age ≥18y., experiencing chronic psychostimulant (nicotine, amphetamine, cocaine), sedative (benzodiazepine, opioids) and/or cannabinoid use. |
2021-06-28 |
2023-08-13 |
human |
| Elizabeth M Doncheck, Gage T Liddiard, Chaz D Konrath, Xiaojie Liu, Laikang Yu, Luke A Urbanik, Matthew R Herbst, Margot C DeBaker, Nicholas Raddatz, Erik C Van Newenhizen, Jacob Mathy, Marieke R Gilmartin, Qing-Song Liu, Cecilia J Hillard, John R Mantsc. Sex, stress, and prefrontal cortex: influence of biological sex on stress-promoted cocaine seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 12. 2021-06-23. PMID:32303052. |
we previously demonstrated that a stressor (footshock) can potentiate cocaine seeking in male rats via glucocorticoid-dependent cannabinoid type-1 receptor (cb1r)-mediated actions in the prelimbic prefrontal cortex (prl-pfc). |
2021-06-23 |
2023-08-13 |
rat |