| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Przemysław Adamczyk, Joanna Miszkiel, Andrew C McCreary, Małgorzata Filip, Mariusz Papp, Edmund Przegalińsk. The effects of cannabinoid CB1, CB2 and vanilloid TRPV1 receptor antagonists on cocaine addictive behavior in rats. Brain research. vol 1444. 2012-11-13. PMID:22325096. |
there is evidence that indicates that tonic activation of cannabinoid cb1 receptors plays a role in extinction/reinstatement of cocaine seeking-behavior but is not involved in the maintenance of cocaine self-administration. |
2012-11-13 |
2023-08-12 |
rat |
| Przemysław Adamczyk, Joanna Miszkiel, Andrew C McCreary, Małgorzata Filip, Mariusz Papp, Edmund Przegalińsk. The effects of cannabinoid CB1, CB2 and vanilloid TRPV1 receptor antagonists on cocaine addictive behavior in rats. Brain research. vol 1444. 2012-11-13. PMID:22325096. |
to further explore the importance of other endocannabinoid-related receptors in an animal model of cocaine addiction, the present paper examines cannabinoid cb2 receptor antagonist n-((1s)-endo-1,3,3-trimethylbicyclo(2.2.1)heptan-2-yl)-5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-pyrazole-3-carboxamide (sr144528) and the transient receptor potential vanilloid type-1 (trpv1) receptor antagonist n-(3-methoxyphenyl)-4-chlorocinnamide (sb366791) on intravenous (i.v.) |
2012-11-13 |
2023-08-12 |
rat |
| Bertin Dufaux, Ronald Agius, Thomas Nadulski, Hans-Gerhard Kah. Comparison of urine and hair testing for drugs of abuse in the control of abstinence in driver's license re-granting. Drug testing and analysis. vol 4. issue 6. 2012-11-05. PMID:22447399. |
in 2010, we screened 14 000 urine and 3900 hair samples for amphetamines, methamphetamines, cannabinoids, cocaine, opiates, methadone, and benzodiazepines as well as for ethylglucuronide. |
2012-11-05 |
2023-08-12 |
human |
| Simona Pichini, Roberto De Luca, Manuela Pellegrini, Emilia Marchei, Maria Concetta Rotolo, Roberta Spoletini, Paola D'Aloja, Roberta Pacifici, Claudia Mortali, Giulia Scaravell. Hair and urine testing to assess drugs of abuse consumption in couples undergoing assisted reproductive technology (ART). Forensic science international. vol 218. issue 1-3. 2012-09-25. PMID:22018744. |
urine testing showed an overall 4.8% (17 individuals) positivity to drugs of abuse: 4.2% to cannabinoids, 1.4% to cocaine and 0.85% to both drugs. |
2012-09-25 |
2023-08-12 |
Not clear |
| Sebastian Broecker, Sieglinde Herre, Fritz Prags. General unknown screening in hair by liquid chromatography-hybrid quadrupole time-of-flight mass spectrometry (LC-QTOF-MS). Forensic science international. vol 218. issue 1-3. 2012-09-25. PMID:22036310. |
basic drugs and metabolites such as opioides, cocaine, amphetamines, several groups of antidepressants, neuroleptics, beta-blockers or the metamizole metabolite noramidopyrine were found with high frequency whereas acidic and several neutral drugs such as cannabinoids, salicylic acid, furosemide, barbiturates, phenprocoumone or cardiac glycosides could not be detected with sufficient sensitivity, mainly because of the low ion yield of positive esi for these compounds. |
2012-09-25 |
2023-08-12 |
Not clear |
| Auxiliadora Aracil-Fernández, José M Trigo, María S García-Gutiérrez, Antonio Ortega-Álvaro, Alexander Ternianov, Daniela Navarro, Patricia Robledo, Pere Berbel, Rafael Maldonado, Jorge Manzanare. Decreased cocaine motor sensitization and self-administration in mice overexpressing cannabinoid CB₂ receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22414816. |
decreased cocaine motor sensitization and self-administration in mice overexpressing cannabinoid cb₂ receptors. |
2012-09-21 |
2023-08-12 |
mouse |
| Auxiliadora Aracil-Fernández, José M Trigo, María S García-Gutiérrez, Antonio Ortega-Álvaro, Alexander Ternianov, Daniela Navarro, Patricia Robledo, Pere Berbel, Rafael Maldonado, Jorge Manzanare. Decreased cocaine motor sensitization and self-administration in mice overexpressing cannabinoid CB₂ receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22414816. |
the potential involvement of the cannabinoid cb₂ receptors (cb₂r) in the adaptive responses induced by cocaine was studied in transgenic mice overexpressing the cb₂r (cb₂xp) and in wild-type (wt) littermates. |
2012-09-21 |
2023-08-12 |
mouse |
| D A Kupferschmidt, A E Newman, R Boonstra, S Er. Antagonism of cannabinoid 1 receptors reverses the anxiety-like behavior induced by central injections of corticotropin-releasing factor and cocaine withdrawal. Neuroscience. vol 204. 2012-07-23. PMID:21784132. |
antagonism of cannabinoid 1 receptors reverses the anxiety-like behavior induced by central injections of corticotropin-releasing factor and cocaine withdrawal. |
2012-07-23 |
2023-08-12 |
rat |
| L K Vaughn, J R Mantsch, O Vranjkovic, G Stroh, M Lacourt, M Kreutter, C J Hillar. Cannabinoid receptor involvement in stress-induced cocaine reinstatement: potential interaction with noradrenergic pathways. Neuroscience. vol 204. 2012-07-23. PMID:21871539. |
this study examined the role of endocannabinoid signaling in stress-induced reinstatement of cocaine seeking and explored the interaction between noradrenergic and endocannabinergic systems in the process. |
2012-07-23 |
2023-08-12 |
mouse |
| L K Vaughn, J R Mantsch, O Vranjkovic, G Stroh, M Lacourt, M Kreutter, C J Hillar. Cannabinoid receptor involvement in stress-induced cocaine reinstatement: potential interaction with noradrenergic pathways. Neuroscience. vol 204. 2012-07-23. PMID:21871539. |
these results are consistent with the hypothesis that stress exposure triggers the endogenous activation of cb1 receptors and that activation of the endocannabinoid system is required for the stress-induced relapse of the mice to cocaine seeking. |
2012-07-23 |
2023-08-12 |
mouse |
| Salvatore Lecca, Miriam Melis, Antonio Luchicchi, Anna Lisa Muntoni, Marco Pisti. Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22169942. |
here, we studied how rmtg neurons regulate both spontaneous firing of da cells and their response to the cannabinoid agonist win55212-2 (win), morphine, cocaine, and nicotine. |
2012-07-20 |
2023-08-12 |
rat |
| Angelo Cecinato, Catia Balducci, Ettore Guerriero, Francesca Sprovieri, Franco Cofon. Possible social relevance of illicit psychotropic substances present in the atmosphere. The Science of the total environment. vol 412-413. 2012-07-19. PMID:22078369. |
atmospheric cocaine and cannabinoids also seemed to be correlated with tumour insurgence and mental disease frequency, respectively. |
2012-07-19 |
2023-08-12 |
Not clear |
| Angelo Cecinato, Catia Balducci, Ettore Guerriero, Francesca Sprovieri, Franco Cofon. Possible social relevance of illicit psychotropic substances present in the atmosphere. The Science of the total environment. vol 412-413. 2012-07-19. PMID:22078369. |
however, further investigations are necessary to elucidate/explain/clarify if the behaviours observed for cocaine vs. the parameters usually adopted to estimate drug abuse prevalence (correspond to an effective relationships)/are directly linked, and to understand why the same approach failed when applied to cannabinoids. |
2012-07-19 |
2023-08-12 |
Not clear |
| V Leyton, D M Sinagawa, K C B G Oliveira, W Schmitz, G Andreuccetti, B S De Martinis, M Yonamine, D R Muno. Amphetamine, cocaine and cannabinoids use among truck drivers on the roads in the State of Sao Paulo, Brazil. Forensic science international. vol 215. issue 1-3. 2012-06-04. PMID:21511416. |
amphetamine, cocaine and cannabinoids use among truck drivers on the roads in the state of sao paulo, brazil. |
2012-06-04 |
2023-08-12 |
Not clear |
| V Leyton, D M Sinagawa, K C B G Oliveira, W Schmitz, G Andreuccetti, B S De Martinis, M Yonamine, D R Muno. Amphetamine, cocaine and cannabinoids use among truck drivers on the roads in the State of Sao Paulo, Brazil. Forensic science international. vol 215. issue 1-3. 2012-06-04. PMID:21511416. |
urine samples were screened for amphetamines, cocaine, and cannabinoids by immunoassay and the confirmation was performed using gas chromatography-mass spectrometry (gc-ms). |
2012-06-04 |
2023-08-12 |
Not clear |
| V Leyton, D M Sinagawa, K C B G Oliveira, W Schmitz, G Andreuccetti, B S De Martinis, M Yonamine, D R Muno. Amphetamine, cocaine and cannabinoids use among truck drivers on the roads in the State of Sao Paulo, Brazil. Forensic science international. vol 215. issue 1-3. 2012-06-04. PMID:21511416. |
ten cases tested positive for cocaine (23.8%), and five for cannabinoids (11.9%). |
2012-06-04 |
2023-08-12 |
Not clear |
| F Musshoff, K M Kirschbaum, K Graumann, C Herzfeld, H Sachs, B Made. Evaluation of two immunoassay procedures for drug testing in hair samples. Forensic science international. vol 215. issue 1-3. 2012-06-04. PMID:21601388. |
following drug classes were included: cannabinoids, opiates, cocaine like substances, amphetamine, methamphetamine (and methylenedioxyamphetamines), methadone, and benzodiazepines. |
2012-06-04 |
2023-08-12 |
Not clear |
| Pascale Basilicata, Maria Pieri, Veronica Settembre, Alessandra Galdiero, Elvira Della Casa, Antonio Acampora, Nadia Miragli. Screening of several drugs of abuse in Italian workplace drug testing: performance comparisons of on-site screening tests and a fluorescence polarization immunoassay-based device. Analytical chemistry. vol 83. issue 22. 2012-03-30. PMID:21992470. |
according to the italian laws, some categories of workers entrusted with duties possibly constituting a threat to security, physical safety, and health of third parties have to be screened to exclude the use/abuse of the following drugs of abuse: opiates, cocaine, cannabinoids, amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine, methadone, and buprenorphine. |
2012-03-30 |
2023-08-12 |
Not clear |
| Maura Castelli, Mauro Federici, Silvia Rossi, Valentina De Chiara, Francesco Napolitano, Valeria Studer, Caterina Motta, Lucia Sacchetti, Rosaria Romano, Alessandra Musella, Giorgio Bernardi, Alberto Siracusano, Howard H Gu, Nicola B Mercuri, Alessandro Usiello, Diego Centonz. Loss of striatal cannabinoid CB1 receptor function in attention-deficit / hyperactivity disorder mice with point-mutation of the dopamine transporter. The European journal of neuroscience. vol 34. issue 9. 2012-02-17. PMID:22034972. |
as striatal da signalling modulates the endocannabinoid system (ecs), the present study was aimed at investigating cannabinoid cb1 receptor (cb1r) function in a model of adhd obtained by triple point-mutation in the dopamine transporter (dat) gene in mice, making them insensitive to cocaine [dat cocaine-insensitive (dat-ci) mice]. |
2012-02-17 |
2023-08-12 |
mouse |
| Rebecca Heltsley, Anne DePriest, David L Black, Tim Robert, Lucas Marshall, Viola M Meadors, Yale H Caplan, Edward J Con. Oral fluid drug testing of chronic pain patients. I. Positive prevalence rates of licit and illicit drugs. Journal of analytical toxicology. vol 35. issue 8. 2012-02-13. PMID:22004671. |
the prevalence of confirmed positive drug groups was as follows: opiates > oxycodone > benzodiazepines > methadone ≈ carisoprodol > fentanyl > cannabinoids ≈ tramadol > cocaine > amphetamines ≈ propoxyphene ≈ buprenorphine > barbiturates > methamphetamine. |
2012-02-13 |
2023-08-12 |
Not clear |