| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L G Miller, D J Greenblatt, R B Roy, F Lopez, L Wecke. Dietary choline intake modulates benzodiazepine receptor binding and gamma-aminobutyric acidA receptor function in mouse brain. The Journal of pharmacology and experimental therapeutics. vol 248. issue 1. 1989-03-03. PMID:2536422. |
based on these findings, the present experiments determined whether chronic choline supplementation or deficiency alters gabaergic function at the level of the gamma-aminobutyric acid (gaba)/benzodiazepine-chloride channel complex. |
1989-03-03 |
2023-08-11 |
mouse |
| L G Miller, D J Greenblatt, R B Roy, F Lopez, L Wecke. Dietary choline intake modulates benzodiazepine receptor binding and gamma-aminobutyric acidA receptor function in mouse brain. The Journal of pharmacology and experimental therapeutics. vol 248. issue 1. 1989-03-03. PMID:2536422. |
dietary choline intake did not alter gaba levels in brain, the binding of [35s]t-butylbicyclophosphorothionate to the chloride channel or the coupling between gaba and either the t-butylbicyclophosphorothionate site or the benzodiazepine site. |
1989-03-03 |
2023-08-11 |
mouse |
| R D Blakely, M B Robinson, S G Amar. Expression of neurotransmitter transport from rat brain mRNA in Xenopus laevis oocytes. Proceedings of the National Academy of Sciences of the United States of America. vol 85. issue 24. 1989-01-26. PMID:2904681. |
transport of radiolabeled l-glutamate, gamma-aminobutyric acid, glycine, dopamine, serotonin, and choline could be measured in single microinjected oocytes with a regional profile consistent with the anatomical distribution of particular neurotransmitter synthesizing soma. |
1989-01-26 |
2023-08-11 |
rat |
| C J Somps, C L Boyajian, M W Luttge. Changes in neurotransmitter uptake in the spinal cord following peripheral nerve injury. Synapse (New York, N.Y.). vol 2. issue 2. 1988-10-20. PMID:2901793. |
the amount of transmitter substance recovered from these fractions was strongly dependent upon the amount of time following nerve injury and on the specific transmitter or precursor being examined (gaba, glutamate, glycine, and choline chloride). |
1988-10-20 |
2023-08-11 |
mouse |
| S P Arnerić, J I Woo, M P Meeley, D J Rei. Spontaneous release of endogenous aspartate and glutamate from rat striatal slices is increased following destruction of local neurons by ibotenic acid. Neurochemical research. vol 13. issue 5. 1988-09-22. PMID:2900479. |
the effectiveness and specificity of the lesion were confirmed by measuring the enzyme activity associated with extrinsic dopamine neurons (tyrosine hydroxylase; 111 +/- 14%), intrinsic gaba neurons (glutamic acid decarboxylase; 19 +/- 7%) and intrinsic acetylcholine neurons (choline acetyltranferase; 37 +/- 10%). |
1988-09-22 |
2023-08-11 |
rat |
| S Nakamura, Y Nakagawa, M Kawai, M Tohyama, T Ishihar. AF64A(ethylcholine aziridinium ion)-induced basal forebrain lesion impairs maze performance. Behavioural brain research. vol 29. issue 1-2. 1988-09-12. PMID:3401315. |
there was a marked decrease in cortical uptake of [3h]choline, but [3h]gaba and [3h]dopamine uptake was not affected by the injection. |
1988-09-12 |
2023-08-11 |
rat |
| T G Robinson, P M Bear. Excitant amino acid projections from rat amygdala and thalamus to nucleus accumbens. Brain research bulletin. vol 20. issue 4. 1988-08-26. PMID:3293707. |
high affinity uptake of d-[3h]aspartate, [3h]choline and [3h]gaba was examined in synaptosomal-containing preparations of rat nucleus accumbens septi 7 to 10 days after unilateral or bilateral n-methyl-d-aspartate lesions confined to the parataenial nucleus of the thalamus or the basolateral nucleus of the amygdala. |
1988-08-26 |
2023-08-11 |
rat |
| T G Robinson, P M Bear. Excitant amino acid projections from rat amygdala and thalamus to nucleus accumbens. Brain research bulletin. vol 20. issue 4. 1988-08-26. PMID:3293707. |
uptake of both d-[3h]aspartate and [3h]choline was significantly reduced (11% and 14% less than control, respectively) by unilateral lesion of the thalamus, whereas [3h]gaba uptake was unaffected. |
1988-08-26 |
2023-08-11 |
rat |
| T G Robinson, P M Bear. Excitant amino acid projections from rat amygdala and thalamus to nucleus accumbens. Brain research bulletin. vol 20. issue 4. 1988-08-26. PMID:3293707. |
d-[3h]aspartate uptake was significantly reduced (26% less than control) following unilateral lesion of the amygdala, whereas both [3h]gaba and [3h]choline uptake were unaffected. |
1988-08-26 |
2023-08-11 |
rat |
| S Weis. Excitatory amino acid-evoked release of gamma-[3H]aminobutyric acid from striatal neurons in primary culture. Journal of neurochemistry. vol 51. issue 2. 1988-08-24. PMID:3392538. |
glutamate-, aspartate-, and n-methyl-d-aspartate-evoked gaba releases were augmented when calcium was omitted from the bathing medium and reduced when sodium was replaced with choline or lithium. |
1988-08-24 |
2023-08-11 |
mouse |
| J P Pin, J Bockaer. Multiple voltage-sensitive calcium channels are probably involved in endogenous GABA release from striatal neurones differentiated in primary culture. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 2. 1988-01-11. PMID:2446149. |
when na+ ions were replaced by choline, basal and k+-evoked gaba release was significantly increased. |
1988-01-11 |
2023-08-11 |
mouse |
| A Pittaluga, M Raiter. Choline increases endogenous GABA release in rat hippocampus by a mechanism sensitive to hemicholinium-3. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 3. 1988-01-11. PMID:3683599. |
choline increases endogenous gaba release in rat hippocampus by a mechanism sensitive to hemicholinium-3. |
1988-01-11 |
2023-08-11 |
rat |
| A Pittaluga, M Raiter. Choline increases endogenous GABA release in rat hippocampus by a mechanism sensitive to hemicholinium-3. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 3. 1988-01-11. PMID:3683599. |
the effects of choline (ch) on the spontaneous release of endogenous gamma-aminobutyric acid (gaba) and of 3h-gaba were studied in superfused rat hippocampal synaptosomes. |
1988-01-11 |
2023-08-11 |
rat |
| A Pittaluga, M Raiter. Choline increases endogenous GABA release in rat hippocampus by a mechanism sensitive to hemicholinium-3. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 3. 1988-01-11. PMID:3683599. |
choline enhanced in a concentration-dependent way the release of endogenous gaba but did not affect that of the radioactive aminoacid. |
1988-01-11 |
2023-08-11 |
rat |
| E Morales, R Tapi. Neurotransmitters of the cerebellar glomeruli: uptake and release of labeled gamma-aminobutyric acid, glycine, serotonin and choline in a purified glomerulus fraction and in granular layer slices. Brain research. vol 420. issue 1. 1987-12-30. PMID:3676746. |
neurotransmitters of the cerebellar glomeruli: uptake and release of labeled gamma-aminobutyric acid, glycine, serotonin and choline in a purified glomerulus fraction and in granular layer slices. |
1987-12-30 |
2023-08-11 |
rat |
| E Morales, R Tapi. Neurotransmitters of the cerebellar glomeruli: uptake and release of labeled gamma-aminobutyric acid, glycine, serotonin and choline in a purified glomerulus fraction and in granular layer slices. Brain research. vol 420. issue 1. 1987-12-30. PMID:3676746. |
we have studied some properties of the uptake and release of labeled gamma-aminobutyric acid (gaba), glycine, serotonin and choline in a purified fraction of glomeruli and in slices of the granular layer of the rat cerebellum. |
1987-12-30 |
2023-08-11 |
rat |
| E M Meyer, C M West, B R Stevens, V Chau, M T Nguyen, J H Judkin. Ubiquitin-directed antibodies inhibit neuronal transporters in rat brain synaptosomes. Journal of neurochemistry. vol 49. issue 6. 1987-12-23. PMID:2890715. |
affinity-purified antibodies specific for ubiquitin were found to inhibit the sodium-dependent uptake of [3h]choline, gamma-[3h]aminobutyric acid [( 3h]gaba), [3h]glutamate, [3h]norepinephrine, [3h]aspartate, and [3h]serotonin in rat cerebral cortical synaptosomes at a low concentration (10 micrograms/ml). |
1987-12-23 |
2023-08-11 |
rat |
| J Shirakawa, K Taniyama, C Tanak. gamma-Aminobutyric acid-induced modulation of acetylcholine release from the guinea pig lung. The Journal of pharmacology and experimental therapeutics. vol 243. issue 1. 1987-12-09. PMID:2889826. |
gamma-aminobutyric acid (gaba) content was measured biochemically and the effect of gaba on the release of [3h]acetylcholine (ach) was studied in strips of the guinea pig lung preloaded with [3h]choline. |
1987-12-09 |
2023-08-11 |
Not clear |
| M S Santos, P P Gonçalves, A P Carvalh. Compartmentation and release of exogenous GABA in sheep brain synaptosomes. Neurochemical research. vol 12. issue 3. 1987-06-26. PMID:3587499. |
when choline replaces external na+, the [3h]gaba release is absolutely ca2+-dependent, and the [3h]gaba released also comes mostly from the cytoplasmic pool. |
1987-06-26 |
2023-08-11 |
Not clear |
| T G Cooper, T W Gudermann, C H Yeun. Characteristics of the transport of carnitine into the cauda epididymidis of the rat as ascertained by luminal perfusion in vitro. International journal of andrology. vol 9. issue 5. 1987-06-10. PMID:3570531. |
the transport of l-carnitine (50 microm) was significantly inhibited by 500 microm d-carnitine, palmitoyl l-carnitine and deoxycarnitine but not by trimethylammonium iodide, trimethyl phosphate, acetyl-l-carnitine, choline, betaine, gamma-aminobutyric acid or dl-carnitinamide. |
1987-06-10 |
2023-08-11 |
rat |