| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P E North, R E Mra. Synaptosomal uptake of choline and of gamma-aminobutyric acid: effects of ethanol and of dimethylsulfoxide. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2626218. |
dmso alone (2-10% v/v) inhibited synaptosomal uptakes of gaba and of choline in a concentration-dependent fashion, with choline uptake inhibited to a greater degree than gaba uptake. |
1990-04-12 |
2023-08-11 |
Not clear |
| P E North, R E Mra. Synaptosomal uptake of choline and of gamma-aminobutyric acid: effects of ethanol and of dimethylsulfoxide. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2626218. |
dmso at low concentrations (0.3-1.5% v/v) had no effect on inhibition of gaba and choline uptake by 0.6 m ethanol, and higher dmso concentrations resulted only in further inhibition. |
1990-04-12 |
2023-08-11 |
Not clear |
| P E North, R E Mra. Synaptosomal uptake of choline and of gamma-aminobutyric acid: effects of ethanol and of dimethylsulfoxide. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2626218. |
similarly, ethanol (0.3 m) had no effect on inhibition of gaba and choline uptake by 5% (v/v) dmso, and higher ethanol concentrations (0.6-1.2 m) resulted only in further inhibition. |
1990-04-12 |
2023-08-11 |
Not clear |
| P E North, R E Mra. Synaptosomal uptake of choline and of gamma-aminobutyric acid: effects of ethanol and of dimethylsulfoxide. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2626218. |
we conclude that the inhibiting effects of ethanol on synaptosomal gaba and choline uptake are not reversed by dmso. |
1990-04-12 |
2023-08-11 |
Not clear |
| M U Drüsedau, R Yates, N P Kurstjens, R C Cantril. Uptake and stimulation-evoked release of tritiated neurotransmitters from slices of the rat rostral ventral medulla containing the nucleus raphe magnus: implications for pathways controlling nociception. The International journal of biochemistry. vol 21. issue 8. 1990-01-11. PMID:2573548. |
slices of this area of the brainstem may be labelled with tritiated noradrenaline, dopamine, serotonin, gaba and choline. |
1990-01-11 |
2023-08-11 |
rat |
| M U Drüsedau, R Yates, N P Kurstjens, R C Cantril. Uptake and stimulation-evoked release of tritiated neurotransmitters from slices of the rat rostral ventral medulla containing the nucleus raphe magnus: implications for pathways controlling nociception. The International journal of biochemistry. vol 21. issue 8. 1990-01-11. PMID:2573548. |
uptake was greatest for noradrenaline and dopamine, gaba was intermediate and serotonin and choline were poorly accumulated. |
1990-01-11 |
2023-08-11 |
rat |
| P H Anderse. The dopamine inhibitor GBR 12909: selectivity and molecular mechanism of action. European journal of pharmacology. vol 166. issue 3. 1989-11-27. PMID:2530094. |
gbr 12909 (3 microm) was without effect on muscarinic, alpha 2, beta 1 + 2, gamma-aminobutyric acid (gaba) and benzodiazepine receptors, and on choline and gaba uptake carriers. |
1989-11-27 |
2023-08-11 |
Not clear |
| J R O'Kusky, E G McGee. Methylmercury-induced movement and postural disorders in developing rat: high-affinity uptake of choline, glutamate, and gamma-aminobutyric acid in the cerebral cortex and caudate-putamen. Journal of neurochemistry. vol 53. issue 4. 1989-10-12. PMID:2570131. |
methylmercury-induced movement and postural disorders in developing rat: high-affinity uptake of choline, glutamate, and gamma-aminobutyric acid in the cerebral cortex and caudate-putamen. |
1989-10-12 |
2023-08-11 |
rat |
| J R O'Kusky, E G McGee. Methylmercury-induced movement and postural disorders in developing rat: high-affinity uptake of choline, glutamate, and gamma-aminobutyric acid in the cerebral cortex and caudate-putamen. Journal of neurochemistry. vol 53. issue 4. 1989-10-12. PMID:2570131. |
sodium-dependent high-affinity uptake of radiolabeled choline, glutamate, and gamma-aminobutyric acid (gaba) was measured in homogenates of cerebral cortex and caudate-putamen. |
1989-10-12 |
2023-08-11 |
rat |
| O A Petroff, D D Spencer, J R Alger, J W Prichar. High-field proton magnetic resonance spectroscopy of human cerebrum obtained during surgery for epilepsy. Neurology. vol 39. issue 9. 1989-10-12. PMID:2771071. |
frontal and temporal lobe specimens composed of both gray and white matter failed to show statistically significant differences in the concentrations of creatine, n-acetylaspartate, alanine, aspartate gamma-aminobutyric acid, glutamate, glycine, taurine, threonine, valine, acetate, choline, beta-hydroxybutyric acid, inositols, lactate pyruvate, or succinate. |
1989-10-12 |
2023-08-11 |
human |
| R E Mrak, P E Nort. Triphasic effects of short chain n-alcohols on synaptic membrane transport of choline and of gamma-aminobutyric acid. Biochimica et biophysica acta. vol 984. issue 1. 1989-09-25. PMID:2765543. |
triphasic effects of short chain n-alcohols on synaptic membrane transport of choline and of gamma-aminobutyric acid. |
1989-09-25 |
2023-08-11 |
Not clear |
| R E Mrak, P E Nort. Triphasic effects of short chain n-alcohols on synaptic membrane transport of choline and of gamma-aminobutyric acid. Biochimica et biophysica acta. vol 984. issue 1. 1989-09-25. PMID:2765543. |
n-alcohols, when added in increasing concentrations, had an unusual triphasic effect on the uptake of choline and of gamma-aminobutyric acid by isolated synaptosomes. |
1989-09-25 |
2023-08-11 |
Not clear |
| J M Schaeffer, H W Haine. Avermectin binding in Caenorhabditis elegans. A two-state model for the avermectin binding site. Biochemical pharmacology. vol 38. issue 14. 1989-08-16. PMID:2751697. |
several putative neurotransmitters including gamma-aminobutyric acid (gaba), carbamyl choline, taurine, glutamate and dopamine were tested and found to have no effect on ivm binding. |
1989-08-16 |
2023-08-11 |
rat |
| R Schliebs, M Zivin, J Steinbach, T Roth. Changes in cholinergic but not in GABAergic markers in amygdala, piriform cortex, and nucleus basalis of the rat brain following systemic administration of kainic acid. Journal of neurochemistry. vol 53. issue 1. 1989-07-13. PMID:2542459. |
three days after systemic administration of kainic acid (15 mg/kg, s.c.), selected cholinergic markers (choline acetyltransferase, acetylcholinesterase, muscarinic acetylcholine receptor, and high-affinity choline uptake) and gabaergic parameters [benzodiazepine and gamma-aminobutyric acid (gaba) receptors] were studied in the frontal and piriform cortex, dorsal hippocampus, amygdaloid complex, and nucleus basalis. |
1989-07-13 |
2023-08-11 |
rat |
| K Kinouchi, S Maeda, K Saito, R Inoki, K Fukumitsu, I Yoshiy. Effects of d- and l-pentazocine on the release and uptake of norepinephrine in rat brain cortex. Research communications in chemical pathology and pharmacology. vol 63. issue 2. 1989-06-06. PMID:2565594. |
both isomers of pentazocine (3 x 10(-5) m) also evoked the release of tritium from slices preloaded with [3h]dopamine and [3h]5-hydroxytryptamine ([3h]5-ht) but did not from those preloaded with [3h] gamma-aminobutyric acid ([3h]gaba) and [3h]choline. |
1989-06-06 |
2023-08-11 |
rat |
| K Kinouchi, S Maeda, K Saito, R Inoki, K Fukumitsu, I Yoshiy. Effects of d- and l-pentazocine on the release and uptake of norepinephrine in rat brain cortex. Research communications in chemical pathology and pharmacology. vol 63. issue 2. 1989-06-06. PMID:2565594. |
both isomers inhibited the uptake of [3h]norepinephrine, [3h]dopamine and [3h]5-ht but not that of [3h]gaba and [3h]choline into synaptosomes prepared from the cortex. |
1989-06-06 |
2023-08-11 |
rat |
| T Nabeshima, Y Noda, K Itoh, T Kameyam. Role of cholinergic and GABAergic neuronal systems in cycloheximide-induced amnesia in mice. Pharmacology, biochemistry, and behavior. vol 31. issue 2. 1989-06-06. PMID:2854264. |
in the cxm (60 mg/kg)-treated mice, a choline esterase inhibitor, physostigmine (phy; 0.125 and 0.25 mg/kg, ip), or gaba agonists, muscimol (1 and 2 mg/kg, ip) and baclofen (6 and 12 mg/kg, ip), given just after training markedly prolonged step down latency (sdl), indicating reversal of amnesia. |
1989-06-06 |
2023-08-11 |
mouse |
| H S Singer, L C Cor. Canine GM2 gangliosidosis: morphological and biochemical analysis. Veterinary pathology. vol 26. issue 2. 1989-06-05. PMID:2540585. |
ligand binding to carrier sites for choline high affinity uptake identified with [3h]hemicholinium-3 was increased, whereas post-synaptic binding to muscarinic cholinergic ([3h]qnb) and gamma-aminobutyric acid receptors ([3h]muscimol) was reduced. |
1989-06-05 |
2023-08-11 |
Not clear |
| S K Sedowofia, J Innes, A Peter, E Alleva, A Manning, R M Clayto. Differential effects of prenatal exposure to phenobarbital on the behaviour and neurochemistry of CBA and C57BL/6J mice. Psychopharmacology. vol 97. issue 1. 1989-05-30. PMID:2496418. |
in neurochemical analyses, uptake of neurotransmitters by cerebral cultures from cba showed that uptake of gaba was increased by 5%, choline by 95%, dopamine 120%, serotonin 165% and noradrenaline by 160% in cultures from drug exposed embryos compared to controls. |
1989-05-30 |
2023-08-11 |
mouse |
| S K Sedowofia, J Innes, A Peter, E Alleva, A Manning, R M Clayto. Differential effects of prenatal exposure to phenobarbital on the behaviour and neurochemistry of CBA and C57BL/6J mice. Psychopharmacology. vol 97. issue 1. 1989-05-30. PMID:2496418. |
in cerebral cultures from c57, gaba uptake was reduced by 18%, choline 33%, dopamine 35% and noradrenaline by 25%. |
1989-05-30 |
2023-08-11 |
mouse |