| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W R Millington, A M Goldber. Precursor dependence of acetylcholine release from rat brain in vitro. Brain research. vol 243. issue 2. 1982-10-21. PMID:7104738. |
these experiments were designed to test the extent to which the concentration of extracellular choline affects the synthesis and subsequent release of acetylcholine (ach) by rat cortex in vitro. |
1982-10-21 |
2023-08-12 |
rat |
| W R Millington, A M Goldber. Precursor dependence of acetylcholine release from rat brain in vitro. Brain research. vol 243. issue 2. 1982-10-21. PMID:7104738. |
the ach and choline concentrations of rat cortex in vitro were similarly unaffected by in vivo choline administration. |
1982-10-21 |
2023-08-12 |
rat |
| W R Millington, A M Goldber. Precursor dependence of acetylcholine release from rat brain in vitro. Brain research. vol 243. issue 2. 1982-10-21. PMID:7104738. |
these results indicate that ach release from rat cortex, in vitro, depends upon the direct availability of extracellular choline under conditions of prolonged neuronal depolarization. |
1982-10-21 |
2023-08-12 |
rat |
| P Bagnoli, A Beaudet, M Stella, M Cuéno. Selective retrograde labeling of cholinergic neurons with [3H]choline. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 1. issue 7. 1982-10-21. PMID:7346577. |
[3h]choline injection in the rat hippocampus leads to perikaryal retrograde labeling in the ipsilateral medial septal nuclease and nucleus of the diagonal band, thus delineating an established cholinergic pathway, while only diffuse presumably anterograde labeling was observed in the lateral septum, the entorhinal cortex, and the opposite hippocampus. |
1982-10-21 |
2023-08-12 |
rat |
| A Fisher, C R Mantione, D J Abraham, I Hani. Long-term central cholinergic hypofunction induced in mice by ethylcholine aziridinium ion (AF64A) in vivo. The Journal of pharmacology and experimental therapeutics. vol 222. issue 1. 1982-08-26. PMID:6896342. |
seven days after a single injection of 65 nmol of af64a i.c.v., there was a significant decrease in acetylcholine content in the cortex, striatum and hippocampus, but no change in choline levels. |
1982-08-26 |
2023-08-12 |
mouse |
| A V Davidenko, A N Vasil'ev, N A Kucherenk. [Inhibition of noradrenaline and choline active capture by rat brain synaptosomes in the presence of terephthalic acid and its dimethyl ester]. Ukrainskii biokhimicheskii zhurnal (1978). vol 54. issue 2. 1982-07-08. PMID:7080225. |
the system of [14c] noradrenaline and [3h] choline trapping by rat brain cortex synaptosomes was studied under the effect of terephthalic acid and its dimethyl ester. |
1982-07-08 |
2023-08-12 |
rat |
| S Sorbi, P Antuono, L Amaducc. Choline acetyltransferase and acetylcholinesterase abnormalities in senile dementia: importance of biochemical measurements in human post-mortem brain specimens. Italian journal of neurological sciences. vol 1. issue 2. 1982-06-24. PMID:7040296. |
choline acetyl transferase decreased during aging in normal brain when measured in the cerebral cortex. |
1982-06-24 |
2023-08-12 |
human |
| P P Rowell, G E Dunca. The subsynaptosomal distribution and release of [3H]acetylcholine synthesized by rat cerebral cortical synaptosomes. Neurochemical research. vol 6. issue 12. 1982-06-14. PMID:7339505. |
synaptosomes were prepared from rat cerebral cortex and incubated in [3h]choline for periods ranging from 1 to 90 min. |
1982-06-14 |
2023-08-12 |
rat |
| O Nordström, A Westlind, A Undén, B Meyerson, C Sachs, T Bartfa. Pre- and postsynaptic muscarinic receptors in surgical samples from human cerebral cortex. Brain research. vol 234. issue 2. 1982-05-21. PMID:6277431. |
presynaptic muscarinic receptors were studied in slices of the cerebral cortex, which were loaded with [3h]choline. |
1982-05-21 |
2023-08-12 |
human |
| N Brunello, D L Cheney, E Cost. Increase in exogenous choline fails to elevate the content or turnover rate of cortical, striatal, or hippocampal acetylcholine. Journal of neurochemistry. vol 38. issue 4. 1982-05-21. PMID:7062035. |
the content of choline and acetylcholine and the turnover rate of acetylcholine in striatum, hippocampus, and cerebral cortex were measured following changes in dietary choline, intraperitoneal choline, or intravenous infusion of choline. |
1982-05-21 |
2023-08-12 |
rat |
| F Pedata, G Lo Conte, S Sorbi, I Marconcini-Pepeu, G Pepe. Changes in high affinity choline uptake in rat cortex following lesions of the magnocellular forebrain nuclei. Brain research. vol 233. issue 2. 1982-05-12. PMID:7059814. |
changes in high affinity choline uptake in rat cortex following lesions of the magnocellular forebrain nuclei. |
1982-05-12 |
2023-08-12 |
rat |
| F Pedata, G Lo Conte, S Sorbi, I Marconcini-Pepeu, G Pepe. Changes in high affinity choline uptake in rat cortex following lesions of the magnocellular forebrain nuclei. Brain research. vol 233. issue 2. 1982-05-12. PMID:7059814. |
high affinity choline uptake (hacu) and choline acetyltransferase (cat) were measured in the cerebral cortex of rats 4 and 20 days after placing electrolytic lesions in the magnocellular forebrain nuclei (mfn) or in the pallidum. |
1982-05-12 |
2023-08-12 |
rat |
| R T Bartus, R L Dean, K A Sherman, E Friedman, B Bee. Profound effects of combining choline and piracetam on memory enhancement and cholinergic function in aged rats. Neurobiology of aging. vol 2. issue 2. 1982-01-20. PMID:7301036. |
animals in each group were tested behaviorally for retention of a one trial passive avoidance task, and biochemically to determine changes in choline and acetylcholine levels in hippocampus, cortex and striatum. |
1982-01-20 |
2023-08-12 |
human |
| R T Bartus, R L Dean, K A Sherman, E Friedman, B Bee. Profound effects of combining choline and piracetam on memory enhancement and cholinergic function in aged rats. Neurobiology of aging. vol 2. issue 2. 1982-01-20. PMID:7301036. |
although choline administration raised choline content about 50% in striatum and cortex, changes in acetylcholine levels were much more subtle (only 6-10%). |
1982-01-20 |
2023-08-12 |
human |
| C R Mantione, A Fisher, I Hani. The AF64a-treated mouse: possible model for central cholinergic hypofunction. Science (New York, N.Y.). vol 213. issue 4507. 1981-08-27. PMID:6894649. |
a loss in the number of functional, sodium ion-dependent, high-affinity choline transport sites was observed in the cortex and hippocampus of mice given an intracerebroventricular injection of 65 nanomoles of af64a (ethylcholine mustard aziridinium ion) 3 days earlier. |
1981-08-27 |
2023-08-12 |
mouse |
| R S Jone. High-affinity uptake of choline in slices of rat cerebral cortex: effects of antidepressant and anticholinergic drugs. Canadian journal of physiology and pharmacology. vol 59. issue 4. 1981-08-27. PMID:7237257. |
high-affinity uptake of choline in slices of rat cerebral cortex: effects of antidepressant and anticholinergic drugs. |
1981-08-27 |
2023-08-12 |
rat |
| H Bigalke, G Ahnert-Hilger, E Haberman. Tetanus toxin and botulinum A toxin inhibit acetylcholine release from but not calcium uptake into brain tissue. Naunyn-Schmiedeberg's archives of pharmacology. vol 316. issue 2. 1981-08-10. PMID:7242701. |
slices or particles from rat forebrain cortex were preloaded with [3h]choline, and the release of [3h]acetylcholine was evoked with potassium ions in a superfusion system. |
1981-08-10 |
2023-08-12 |
rat |
| J M Gorell, C P Navarro, S P Schwendne. Regional CNS levels of acetylcholine and choline during hypoglycemic stupor and recovery. Journal of neurochemistry. vol 36. issue 1. 1981-04-24. PMID:7463059. |
during insulin stupor in mice, acetylcholine levels in cerebral cortex, cerebellum, brainstem, striatum, and hippocampus were unchanged from control values despite brain glucose concentrations 3-10% of normal, whereas choline levels rose 2.4-3.6-fold in all five cns regions. |
1981-04-24 |
2023-08-12 |
mouse |
| A V Kol'tsova, O Kh Koshtoiant. [Choline sensitivity of sensomotor cortex neurons of rabbits with experimental neuroses]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 30. issue 3. 1981-01-26. PMID:7192033. |
[choline sensitivity of sensomotor cortex neurons of rabbits with experimental neuroses]. |
1981-01-26 |
2023-08-12 |
Not clear |
| F Casamenti, F Pedata, R Corradetti, G Pepe. Acetylcholine input from the cerebral cortex, choline uptake and muscarinic receptors in morphine-dependent, freely-moving rats. Neuropharmacology. vol 19. issue 7. 1980-10-24. PMID:7190653. |
acetylcholine input from the cerebral cortex, choline uptake and muscarinic receptors in morphine-dependent, freely-moving rats. |
1980-10-24 |
2023-08-12 |
rat |