| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cody W Kowalski, Forrest J Ragozzino, Jonathan E M Lindberg, BreeAnne Peterson, Janelle M Lugo, Ryan J McLaughlin, James H Peter. Cannabidiol activation of vagal afferent neurons requires TRPA1. Journal of neurophysiology. vol 124. issue 5. 2021-10-07. PMID:32965166. |
the diverse therapeutic effects of electrical vagus nerve stimulation also result from administration of the nonpsychotropic cannabinoid, cannabidiol (cbd); however, the direct effects of cbd on vagal afferent signaling remain unknown. |
2021-10-07 |
2023-08-13 |
mouse |
| Anne K Schlag, Chandni Hindocha, Rayyan Zafar, David J Nutt, H Valerie Curra. Cannabis based medicines and cannabis dependence: A critical review of issues and evidence. Journal of psychopharmacology (Oxford, England). vol 35. issue 7. 2021-10-07. PMID:33593117. |
we focus on the main issues related to medical cannabis and dependence, including the importance of dose, potency, cannabinoid content, pharmacokinetics and route of administration, frequency of use, as well as set and setting. |
2021-10-07 |
2023-08-13 |
Not clear |
| Justin E LaVigne, Ryan Hecksel, Attila Keresztes, John M Streiche. Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity. Scientific reports. vol 11. issue 1. 2021-10-06. PMID:33859287. |
cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity. |
2021-10-06 |
2023-08-13 |
mouse |
| Justin E LaVigne, Ryan Hecksel, Attila Keresztes, John M Streiche. Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity. Scientific reports. vol 11. issue 1. 2021-10-06. PMID:33859287. |
limited evidence has suggested that terpenes found in cannabis sativa are analgesic, and could produce an "entourage effect" whereby they modulate cannabinoids to result in improved outcomes. |
2021-10-06 |
2023-08-13 |
mouse |
| Justin E LaVigne, Ryan Hecksel, Attila Keresztes, John M Streiche. Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity. Scientific reports. vol 11. issue 1. 2021-10-06. PMID:33859287. |
we thus investigated cannabis sativa terpenes alone and with the cannabinoid agonist win55,212 using in vitro and in vivo approaches. |
2021-10-06 |
2023-08-13 |
mouse |
| Justin E LaVigne, Ryan Hecksel, Attila Keresztes, John M Streiche. Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity. Scientific reports. vol 11. issue 1. 2021-10-06. PMID:33859287. |
our findings suggest that these cannabis terpenes are multifunctional cannabimimetic ligands that provide conceptual support for the entourage effect hypothesis and could be used to enhance the therapeutic properties of cannabinoids. |
2021-10-06 |
2023-08-13 |
mouse |
| Ava Mason, Musa Sami, Caitlin Notley, Sagnik Bhattacharyy. Are researchers getting the terms used to denote different types of recreational cannabis right?-a user perspective. Journal of cannabis research. vol 3. issue 1. 2021-10-06. PMID:33926566. |
current categorisation in research focuses on the two main cannabinoids: delta-9-tetrahydrocannabinol (thc) and cannabidiol (cbd); and two different species of cannabis: indica and sativa. |
2021-10-06 |
2023-08-13 |
human |
| Maya R Jacobson, Jeremy J Watts, Tania Da Silva, Rachel F Tyndale, Pablo M Rusjan, Sylvain Houle, Alan A Wilson, Ruth A Ross, Isabelle Boileau, Romina Mizrah. Fatty acid amide hydrolase is lower in young cannabis users. Addiction biology. vol 26. issue 1. 2021-10-05. PMID:31960544. |
we have recently shown that levels of fatty acid amide hydrolase (faah), the enzyme that metabolizes the endocannabinoid anandamide, are lower in the brains of adult cannabis users (cus) (34 ± 11 years of age), tested during early abstinence. |
2021-10-05 |
2023-08-13 |
human |
| Shunaha Kim-Fine, Jamie Greenfield, Kathleen H Chaput, Magali Robert, Luanne M Met. Cannabinoids and bladder symptoms in multiple sclerosis. Multiple sclerosis and related disorders. vol 54. 2021-10-05. PMID:34216995. |
while there are data that support a biological mechanism by which cannabinoids can impact various other symptoms of ms, the evidence of effectiveness of cannabis as a treatment for bladder symptoms remains unsettled. |
2021-10-05 |
2023-08-13 |
Not clear |
| Miriam Stempfer, Vera Reinstadler, Anna Lang, Herbert Oberache. Analysis of cannabis seizures by non-targeted liquid chromatography-tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis. vol 205. 2021-10-05. PMID:34474231. |
due to the popularity of recreational cannabis use, contamination of this drug with diverse classes of chemicals, including pesticides, mycotoxins, and synthetic cannabinoids, has been identified as major threat for public health. |
2021-10-05 |
2023-08-13 |
Not clear |
| Jessica Nixon, Hanan Abramovici, Ashley Cabecinha, Camilo Martinez-Farina, Joseph Hui, Lee Elli. Assessing the bioactivity of cannabis extracts in larval zebrafish. Journal of cannabis research. vol 3. issue 1. 2021-10-05. PMID:34598738. |
whole-plant cannabis extracts are consumed by the public for medical and non-medical ("recreational") purposes but are poorly researched compared to pure cannabinoids. |
2021-10-05 |
2023-08-13 |
zebrafish |
| Jessica Nixon, Hanan Abramovici, Ashley Cabecinha, Camilo Martinez-Farina, Joseph Hui, Lee Elli. Assessing the bioactivity of cannabis extracts in larval zebrafish. Journal of cannabis research. vol 3. issue 1. 2021-10-05. PMID:34598738. |
there is emerging evidence that cannabis extracts comprising complex mixtures of cannabinoids may have different biological effects from that of pure cannabinoids. |
2021-10-05 |
2023-08-13 |
zebrafish |
| Amir Fruman, Refael Stryjer, Shira Weizman, Assaf Shele. Creatine kinase levels in psychotic patients who use cannabinoids. International clinical psychopharmacology. vol 36. issue 1. 2021-10-04. PMID:33165025. |
higher rate of elevated creatine kinase levels was observed in hospitalized psychotic cannabinoid users, possibly due to a cannabis activity at peripheral or brain tissues. |
2021-10-04 |
2023-08-13 |
Not clear |
| Isabel González-Mariscal, Beatriz Carmona-Hidalgo, Matthias Winkler, Juan D Unciti-Broceta, Alejandro Escamilla, María Gómez-Cañas, Javier Fernández-Ruiz, Bernd L Fiebich, Silvana-Yanina Romero-Zerbo, Francisco J Bermúdez-Silva, Juan A Collado, Eduardo Muño. (+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB Pharmacological research. vol 169. 2021-10-04. PMID:34019978. |
(+)-trans-cannabidiol-2-hydroxy pentyl is a dual cb natural cannabidiol ((-)-cbd) and its derivatives have increased interest for medicinal applications due to their broad biological activity spectrum, including targeting of the cannabinoid receptors type 1 (cb |
2021-10-04 |
2023-08-13 |
Not clear |
| Liesl Janssens, Annelies Cannaert, Matthew J Connolly, Huiling Liu, Christophe P Stov. In vitro activity profiling of Cumyl-PEGACLONE variants at the CB Drug testing and analysis. vol 12. issue 9. 2021-10-01. PMID:32490586. |
scras are known to typically exert higher cannabinoid activity than tetrahydrocannabinol from cannabis, thereby entailing a greater health risk. |
2021-10-01 |
2023-08-13 |
Not clear |
| Chiung-Wei Huang, Pi-Chen Lin, Jian-Lin Chen, Ming-Jen Le. Cannabidiol Selectively Binds to the Voltage-Gated Sodium Channel Na Biomedicines. vol 9. issue 9. 2021-10-01. PMID:34572327. |
cannabidiol selectively binds to the voltage-gated sodium channel na cannabidiol (cbd), one of the cannabinoids from the cannabis plant, can relieve the myotonia resulting from sodium channelopathy, which manifests as repetitive discharges of muscle membrane. |
2021-10-01 |
2023-08-13 |
Not clear |
| Julie Schjødtz Hansen, Rikke Middelhede Hansen, Thor Petersen, Stefan Gustavsen, Annette Bang Oturai, Finn Sellebjerg, Eva Aggerholm Sædder, Helge Kasch, Peter Vestergaard Rasmussen, Nanna Brix Finnerup, Kristina Bacher Svendse. The Effect of Cannabis-Based Medicine on Neuropathic Pain and Spasticity in Patients with Multiple Sclerosis and Spinal Cord Injury: Study Protocol of a National Multicenter Double-Blinded, Placebo-Controlled Trial. Brain sciences. vol 11. issue 9. 2021-10-01. PMID:34573231. |
however, knowledge about effects, side effects, choice of active cannabinoids (Δ9-tetrahydrocannabinol (thc), cannabidiol (cbd) alone or in combination), and doses of cbm remains limited. |
2021-10-01 |
2023-08-13 |
Not clear |
| Martina Rabino, Sara Mallia, Elisa Castiglioni, Davide Rovina, Giulio Pompilio, Aoife Gowra. The Endocannabinoid System and Cannabidiol: Past, Present, and Prospective for Cardiovascular Diseases. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577636. |
the endocannabinoid system and cannabidiol: past, present, and prospective for cardiovascular diseases. |
2021-10-01 |
2023-08-13 |
Not clear |
| Martina Rabino, Sara Mallia, Elisa Castiglioni, Davide Rovina, Giulio Pompilio, Aoife Gowra. The Endocannabinoid System and Cannabidiol: Past, Present, and Prospective for Cardiovascular Diseases. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577636. |
this review, following a general overview of cannabis and the endocannabinoid system, assiduously describes its role within the context of cardiovascular diseases, paying particular attention to the janus influence that endocannabinoid system modulators can have on the cardiovascular system. |
2021-10-01 |
2023-08-13 |
Not clear |
| Hajra Khurshid, Israa A Qureshi, Nasrin Jahan, Terry R Went, Waleed Sultan, Alisha Sapkota, Michael Alfons. A Systematic Review of Fibromyalgia and Recent Advancements in Treatment: Is Medicinal Cannabis a New Hope? Cureus. vol 13. issue 8. 2021-09-29. PMID:34567876. |
we followed preferred reporting items for systematic review and meta-analysis (prisma) guidelines in searching pubmed, medline (through pubmed), pubmed central, and google scholar using keywords "fibromyalgia, chronic pain, cannabis, cannabinoids, pharmacotherapy, alternative therapy" and medical subject heading (mesh) words. |
2021-09-29 |
2023-08-13 |
human |