| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marc W Manseau, Donald C Gof. Cannabinoids and Schizophrenia: Risks and Therapeutic Potential. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26311150. |
the endocannabinoid system has been implicated in psychosis both related and unrelated to cannabis exposure, and studying this system holds potential to increase understanding of the pathophysiology of schizophrenia. |
2016-07-22 |
2023-08-13 |
human |
| Oier Aizpurua-Olaizola, Umut Soydaner, Ekin Öztürk, Daniele Schibano, Yilmaz Simsir, Patricia Navarro, Nestor Etxebarria, Aresatz Usobiag. Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes. Journal of natural products. vol 79. issue 2. 2016-07-22. PMID:26836472. |
evolution of the cannabinoid and terpene content during the growth of cannabis sativa plants from different chemotypes. |
2016-07-22 |
2023-08-13 |
Not clear |
| Oier Aizpurua-Olaizola, Umut Soydaner, Ekin Öztürk, Daniele Schibano, Yilmaz Simsir, Patricia Navarro, Nestor Etxebarria, Aresatz Usobiag. Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes. Journal of natural products. vol 79. issue 2. 2016-07-22. PMID:26836472. |
the evolution of major cannabinoids and terpenes during the growth of cannabis sativa plants was studied. |
2016-07-22 |
2023-08-13 |
Not clear |
| Doodipala Samba Reddy, Victoria M Golu. The Pharmacological Basis of Cannabis Therapy for Epilepsy. The Journal of pharmacology and experimental therapeutics. vol 357. issue 1. 2016-07-19. PMID:26787773. |
the two chief cannabinoids are Δ-9-tetrahyrdrocannabinol, the major psychoactive component of marijuana, and cannabidiol (cbd), the major nonpsychoactive component of marijuana. |
2016-07-19 |
2023-08-13 |
Not clear |
| Doodipala Samba Reddy, Victoria M Golu. The Pharmacological Basis of Cannabis Therapy for Epilepsy. The Journal of pharmacology and experimental therapeutics. vol 357. issue 1. 2016-07-19. PMID:26787773. |
this article highlights the pharmacological basis of cannabis therapy, with an emphasis on the endocannabinoid mechanisms underlying the emerging neurotherapeutics of cbd in epilepsy. |
2016-07-19 |
2023-08-13 |
Not clear |
| Dana Ekstei. Issues and promise in clinical studies of botanicals with anticonvulsant potential. Epilepsy & behavior : E&B. vol 52. issue Pt B. 2016-07-18. PMID:26341963. |
although the currently available evidence for the use of cannabinoids in epilepsy is similarly lacking, several carefully designed and well controlled industry-sponsored clinical trials of cannabis derivatives are planned to be completed in the next couple of years, providing the needed reliable data for the use of these products. |
2016-07-18 |
2023-08-13 |
human |
| Regina M Krohn, Sean A Parsons, Jakub Fichna, Kamala D Patel, Robin M Yates, Keith A Sharkey, Martin A Stor. Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment. Journal of inflammation (London, England). vol 13. 2016-07-15. PMID:27418880. |
here we examined the effects of the atypical cannabinoid abnormal cannabidiol (abn-cbd) on wound healing, inflammatory cell recruitment and colitis in mice. |
2016-07-15 |
2023-08-13 |
mouse |
| Eric W Bow, John M Rimold. The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation. Perspectives in medicinal chemistry. vol 8. 2016-07-11. PMID:27398024. |
the cannabinoids are members of a deceptively simple class of terpenophenolic secondary metabolites isolated from cannabis sativa highlighted by (-)-Δ(9)-tetrahydrocannabinol (thc), eliciting distinct pharmacological effects mediated largely by cannabinoid receptor (cb1 or cb2) signaling. |
2016-07-11 |
2023-08-13 |
Not clear |
| J Bertolino, L Abdo, D Khau, R Meckenstock, N Sautereau, E Jean, A Greder-Belan, Y Frances, J Cabane, B Grane. [Cannabinoid hyperemesis syndrome: about 6 cases]. La Revue de medecine interne. vol 36. issue 10. 2016-06-29. PMID:25547957. |
the cannabinoid hyperemesis syndrome (chs) is characterized by cyclic episodes of nausea, vomiting, and abdominal pain, and occurs in young adults with long-term cannabis use. |
2016-06-29 |
2023-08-13 |
Not clear |
| Alexander Paulke, Ewgenij Proschak, Kai Sommer, Janosch Achenbach, Cora Wunder, Stefan W Toenne. Synthetic cannabinoids: In silico prediction of the cannabinoid receptor 1 affinity by a quantitative structure-activity relationship model. Toxicology letters. vol 245. 2016-06-29. PMID:26795018. |
among the group of these psychoactive compounds, the synthetic cannabinoids (scbs) are most popular and serve as a substitute of herbal cannabis. |
2016-06-29 |
2023-08-13 |
Not clear |
| Namrata Singh, Jana Hroudová, Zdeněk Fiša. Cannabinoid-Induced Changes in the Activity of Electron Transport Chain Complexes of Brain Mitochondria. Journal of molecular neuroscience : MN. vol 56. issue 4. 2016-06-27. PMID:25820672. |
both cannabinoid receptor agonists, Δ(9)-tetrahydrocannabinol, anandamide, and r-(+)-win55,212-2, and antagonist/inverse agonists of cannabinoid receptors, am251, and cannabidiol were examined in pig brain mitochondria. |
2016-06-27 |
2023-08-13 |
Not clear |
| Nina L Cluny, Catherine M Keenan, Raylene A Reimer, Bernard Le Foll, Keith A Sharke. Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with Δ9-Tetrahydrocannabinol. PloS one. vol 10. issue 12. 2016-06-27. PMID:26633823. |
acute administration of cannabinoid cb1 receptor agonists, or the ingestion of cannabis, induces short-term hyperphagia. |
2016-06-27 |
2023-08-13 |
mouse |
| Robert B Laprairie, Amina M Bagher, Melanie E M Kelly, Eileen M Denovan-Wrigh. Biased Type 1 Cannabinoid Receptor Signaling Influences Neuronal Viability in a Cell Culture Model of Huntington Disease. Molecular pharmacology. vol 89. issue 3. 2016-06-22. PMID:26700564. |
in contrast, cannabinoids that are β-arrestin-biased--such as thc found at high levels in modern varieties of marijuana--may be detrimental to cb1 signaling, particularly in hd where cb1 levels are already reduced. |
2016-06-22 |
2023-08-13 |
Not clear |
| Natalya M Kogan, Eitan Melamed, Elad Wasserman, Bitya Raphael, Aviva Breuer, Kathryn S Stok, Rachel Sondergaard, Ana V Villarreal Escudero, Saja Baraghithy, Malka Attar-Namdar, Silvina Friedlander-Barenboim, Neashan Mathavan, Hanna Isaksson, Raphael Mechoulam, Ralph Müller, Alon Bajayo, Yankel Gabet, Itai Ba. Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 30. issue 10. 2016-06-20. PMID:25801536. |
cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported. |
2016-06-20 |
2023-08-13 |
rat |
| Safwat A Ahmed, Samir A Ross, Desmond Slade, Mohamed M Radwan, Ikhlas A Khan, Mahmoud A ElSohl. Minor oxygenated cannabinoids from high potency Cannabis sativa L. Phytochemistry. vol 117. 2016-06-20. PMID:26093324. |
minor oxygenated cannabinoids from high potency cannabis sativa l. nine oxygenated cannabinoids were isolated from a high potency cannabis sativa l. variety. |
2016-06-20 |
2023-08-13 |
Not clear |
| Sabrina Giacoppo, Maria Galuppo, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzo. A new formulation of cannabidiol in cream shows therapeutic effects in a mouse model of experimental autoimmune encephalomyelitis. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. vol 23. 2016-06-20. PMID:26489494. |
the present study was designed to investigate the efficacy of a new formulation of alone, purified cannabidiol (cbd) (>98 %), the main non-psychotropic cannabinoid of cannabis sativa, as a topical treatment in an experimental model of autoimmune encephalomyelitis (eae), the most commonly used model for multiple sclerosis (ms). |
2016-06-20 |
2023-08-13 |
mouse |
| Margaret Haney, Divya Ramesh, Andrew Glass, Martina Pavlicova, Gillinder Bedi, Ziva D Coope. Naltrexone Maintenance Decreases Cannabis Self-Administration and Subjective Effects in Daily Cannabis Smokers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 11. 2016-06-15. PMID:25881117. |
opioid antagonists modulate cannabinoid effects and may offer a potential approach to reducing cannabis use. |
2016-06-15 |
2023-08-13 |
human |
| Marjan Nikan, Seyed Mohammad Nabavi, Azadeh Manay. Ligands for cannabinoid receptors, promising anticancer agents. Life sciences. vol 146. 2016-06-13. PMID:26764235. |
cannabinoid compounds are unique to cannabis and provide some interesting biological properties. |
2016-06-13 |
2023-08-13 |
Not clear |
| Atheer Zgair, Jonathan C M Wong, Akmal Sabri, Peter M Fischer, David A Barrett, Cris S Constantinescu, Pavel Gershkovic. Development of a simple and sensitive HPLC-UV method for the simultaneous determination of cannabidiol and Δ(9)-tetrahydrocannabinol in rat plasma. Journal of pharmaceutical and biomedical analysis. vol 114. 2016-06-08. PMID:26048666. |
there has been increased interest in the medical use of cannabinoids in recent years, particularly in the predominant natural cannabinoids, cannabidiol (cbd) and Δ(9)-tetrahydrocannabinol (thc). |
2016-06-08 |
2023-08-13 |
rat |
| K R Patil, S N Goyal, C Sharma, C R Patil, S Ojh. Phytocannabinoids for Cancer Therapeutics: Recent Updates and Future Prospects. Current medicinal chemistry. vol 22. issue 30. 2016-06-07. PMID:26179998. |
the ecs includes two g-protein-coupled receptors; the cannabinoid receptors-1 and -2 (cb1 and cb2) for marijuana's psychoactive principle Δ(9)-tetrahydrocannabinol (Δ(9)-thc), their endogenous small lipid ligands; namely anandamide (aea) and 2-arachidonoylglycerol (2-ag), also known as endocannabinoids and the enzymes for endocannabinoid biosynthesis and degradation such as fatty acid amide hydrolase (faah) and monoacylglycerol lipase (magl). |
2016-06-07 |
2023-08-13 |
Not clear |