| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew J Pava, Alexandros Makriyannis, David M Lovinge. Endocannabinoid Signaling Regulates Sleep Stability. PloS one. vol 11. issue 3. 2016-08-12. PMID:27031992. |
the hypnogenic properties of cannabis have been recognized for centuries, but endogenous cannabinoid (endocannabinoid) regulation of vigilance states is poorly characterized. |
2016-08-12 |
2023-08-13 |
mouse |
| Bjoern Moosmann, Nadine Roth, Volker Auwärte. Finding cannabinoids in hair does not prove cannabis consumption. Scientific reports. vol 5. 2016-08-11. PMID:26443501. |
finding cannabinoids in hair does not prove cannabis consumption. |
2016-08-11 |
2023-08-13 |
human |
| Bjoern Moosmann, Nadine Roth, Volker Auwärte. Finding cannabinoids in hair does not prove cannabis consumption. Scientific reports. vol 5. 2016-08-11. PMID:26443501. |
our studies show that all three cannabinoids can be present in hair of non-consuming individuals because of transfer through cannabis consumers, via their hands, their sebum/sweat, or cannabis smoke. |
2016-08-11 |
2023-08-13 |
human |
| Bjoern Moosmann, Nadine Roth, Volker Auwärte. Finding cannabinoids in hair does not prove cannabis consumption. Scientific reports. vol 5. 2016-08-11. PMID:26443501. |
child-custody cases as cannabinoid findings in a child's hair may be caused by close contact to cannabis consumers rather than by inhalation of side-stream smoke. |
2016-08-11 |
2023-08-13 |
human |
| Thomas Heinbockel, Ze-Jun Wan. Cellular Mechanisms of Action of Drug Abuse on Olfactory Neurons. International journal of environmental research and public health. vol 13. issue 1. 2016-08-09. PMID:26703658. |
cannabinoids (Δ9-tetrahydrocannabinol) are the active ingredient of marijuana (cannabis) which is the most commonly abused illicit drug in the usa. |
2016-08-09 |
2023-08-13 |
Not clear |
| Alireza Tahamtan, Masoumeh Tavakoli-Yaraki, Tomasz P Rygiel, Talat Mokhtari-Azad, Vahid Salim. Effects of cannabinoids and their receptors on viral infections. Journal of medical virology. vol 88. issue 1. 2016-08-05. PMID:26059175. |
cannabinoids, the active ingredient in marijuana, and their derivatives have received remarkable attention in the last two decades because they can affect tumor growth and metastasis. |
2016-08-05 |
2023-08-13 |
Not clear |
| Xinmei Yang, Takashi Matsui, Takeshi Kodama, Takahiro Mori, Xiaoxi Zhou, Futoshi Taura, Hiroshi Noguchi, Ikuro Abe, Hiroyuki Morit. Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa. The FEBS journal. vol 283. issue 6. 2016-08-02. PMID:26783002. |
olivetolic acid cyclase (oac) from cannabis sativa, involved in cannabinoid biosynthesis, is the only known plant polyketide cyclase. |
2016-08-02 |
2023-08-13 |
Not clear |
| Julius Gene S Latorre, Elena B Schmid. Cannabis, Cannabinoids, and Cerebral Metabolism: Potential Applications in Stroke and Disorders of the Central Nervous System. Current cardiology reports. vol 17. issue 9. 2016-08-01. PMID:26238742. |
cannabis, cannabinoids, and cerebral metabolism: potential applications in stroke and disorders of the central nervous system. |
2016-08-01 |
2023-08-13 |
human |
| Julius Gene S Latorre, Elena B Schmid. Cannabis, Cannabinoids, and Cerebral Metabolism: Potential Applications in Stroke and Disorders of the Central Nervous System. Current cardiology reports. vol 17. issue 9. 2016-08-01. PMID:26238742. |
previously illegal to possess, cannabis, the plant where natural form of cannabinoids are derived, is now accepted in a growing number of states for medicinal purpose, and some even for recreational use, increasing opportunities for more scientific experimentation. |
2016-08-01 |
2023-08-13 |
human |
| Jacqueline R Argamany, Kelly R Reveles, Bryson Duho. Synthetic cannabinoid hyperemesis resulting in rhabdomyolysis and acute renal failure. The American journal of emergency medicine. vol 34. issue 4. 2016-07-29. PMID:26422191. |
while cannabis was first described as a cause of acute hyperemesis in 2004, a more recent case series also describes the association between cannabinoid hyperemesis and risk of acute renal failure. |
2016-07-29 |
2023-08-13 |
Not clear |
| Philip A Spechler, Catherine A Orr, Bader Chaarani, Kees-Jan Kan, Scott Mackey, Aaron Morton, Mitchell P Snowe, Kelsey E Hudson, Robert R Althoff, Stephen T Higgins, Anna Cattrell, Herta Flor, Frauke Nees, Tobias Banaschewski, Arun L W Bokde, Robert Whelan, Christian Büchel, Uli Bromberg, Patricia Conrod, Vincent Frouin, Dimitri Papadopoulos, Jurgen Gallinat, Andreas Heinz, Henrik Walter, Bernd Ittermann, Penny Gowland, Tomáš Paus, Luise Poustka, Jean-Luc Martinot, Eric Artiges, Michael N Smolka, Gunter Schumann, Hugh Garava. Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat. Developmental cognitive neuroscience. vol 16. 2016-07-26. PMID:26347227. |
given the high density of cannabinoid receptors in the amygdala, our findings suggest cannabis use in early adolescence is associated with hypersensitivity to signals of threat. |
2016-07-26 |
2023-08-13 |
human |
| Shokouh Arjmand, Zohreh Vaziri, Mina Behzadi, Hassan Abbassian, Gary J Stephens, Mohammad Shaban. Cannabinoids and Tremor Induced by Motor-related Disorders: Friend or Foe? Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26152606. |
in the wake of anecdotal, largely uncontrolled, observations claiming the amelioration of some symptoms among cannabis smokers, and the high density of cannabinoid receptors in the areas responsible for motor function, including basal ganglia and cerebellum, many researchers have pursued the question of whether cannabinoid-based compounds could be used therapeutically to alleviate tremor associated with central nervous system diseases. |
2016-07-22 |
2023-08-13 |
Not clear |
| Clementino Ibeas Bih, Tong Chen, Alistair V W Nunn, Michaël Bazelot, Mark Dallas, Benjamin J Whalle. Molecular Targets of Cannabidiol in Neurological Disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26264914. |
until recently, alleged clinical effects from anecdotal reports and the use of licensed cannabinoid medicines are most likely mediated by tetrahydrocannabinol by virtue of: 1) this cannabinoid being present in the most significant quantities in these preparations; and b) the proportion:potency relationship between tetrahydrocannabinol and other plant cannabinoids derived from cannabis. |
2016-07-22 |
2023-08-13 |
Not clear |
| Clementino Ibeas Bih, Tong Chen, Alistair V W Nunn, Michaël Bazelot, Mark Dallas, Benjamin J Whalle. Molecular Targets of Cannabidiol in Neurological Disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26264914. |
however, there has recently been considerable interest in the therapeutic potential for the plant cannabinoid, cannabidiol (cbd), in neurological disorders but the current evidence suggests that cbd does not directly interact with the endocannabinoid system except in vitro at supraphysiological concentrations. |
2016-07-22 |
2023-08-13 |
Not clear |
| Yasmin L Hurd, Michelle Yoon, Alex F Manini, Stephanie Hernandez, Ruben Olmedo, Maria Ostman, Didier Jutras-Aswa. Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26269227. |
multiple cannabinoids derived from the marijuana plant have potential therapeutic benefits but most have not been well investigated, despite the widespread legalization of medical marijuana in the usa and other countries. |
2016-07-22 |
2023-08-13 |
human |
| Yasmin L Hurd, Michelle Yoon, Alex F Manini, Stephanie Hernandez, Ruben Olmedo, Maria Ostman, Didier Jutras-Aswa. Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26269227. |
therapeutic indications will depend on determinations as to which of the multiple cannabinoids, and other biologically active chemicals that are present in the marijuana plant, can be developed to treat specific symptoms and/or diseases. |
2016-07-22 |
2023-08-13 |
human |
| Yasmin L Hurd, Michelle Yoon, Alex F Manini, Stephanie Hernandez, Ruben Olmedo, Maria Ostman, Didier Jutras-Aswa. Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26269227. |
as the legal landscape for medical marijuana unfolds, it is important to distinguish it from "medical cbd" and other specific cannabinoids, that can more appropriately be used to maximize the medicinal potential of the marijuana plant. |
2016-07-22 |
2023-08-13 |
human |
| Jane Sachs, Erin McGlade, Deborah Yurgelun-Tod. Safety and Toxicology of Cannabinoids. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26269228. |
this review will include a brief description of cannabinoids and the endocannabinoid system; a summary of the acute and long-term effects of cannabis; and a discussion of the therapeutic potential of cannabis. |
2016-07-22 |
2023-08-13 |
Not clear |
| Evan C Rosenberg, Richard W Tsien, Benjamin J Whalley, Orrin Devinsk. Cannabinoids and Epilepsy. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26282273. |
in this study, we review current understanding of the endocannabinoid system, characterize the pro- and anticonvulsive effects of cannabinoids [e.g., Δ9-tetrahydrocannabinol and cannabidiol (cbd)], and highlight scientific evidence from pre-clinical and clinical trials of cannabinoids in epilepsy. |
2016-07-22 |
2023-08-13 |
Not clear |
| Evan C Rosenberg, Richard W Tsien, Benjamin J Whalley, Orrin Devinsk. Cannabinoids and Epilepsy. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 4. 2016-07-22. PMID:26282273. |
these studies suggest that cbd avoids the psychoactive effects of the endocannabinoid system to provide a well-tolerated, promising therapeutic for the treatment of seizures, while whole-plant cannabis can both contribute to and reduce seizures. |
2016-07-22 |
2023-08-13 |
Not clear |