| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Volodymyr Pauk, Karel Lem. Forensic applications of supercritical fluid chromatography - mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 1086. 2018-05-14. PMID:29684910. |
cannabis, methamphetamine) as well as new psychoactive substances (synthetic cannabinoids, cathinones and phenethylamines), doping agents (anabolic steroids, stimulants, diuretics, analgesics etc.) |
2018-05-14 |
2023-08-13 |
Not clear |
| Carl R Lupica, Yuhan Hu, Orrin Devinsky, Alexander F Hoffma. Cannabinoids as hippocampal network administrators. Neuropharmacology. vol 124. 2018-05-09. PMID:28392266. |
we also examine potential roles for the hippocampal formation in mediating dysfunctional behavior, and assert that these phenomena reflect disordered physiological activity within the hippocampus and its interactions with other brain regions after exposure to synthetic cannabinoids, and the phytocannabinoids found in marijuana, such as Δ |
2018-05-09 |
2023-08-13 |
Not clear |
| Leepakshi Khurana, Ken Mackie, Daniele Piomelli, Debra A Kendal. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. vol 124. 2018-05-09. PMID:28527758. |
cannabinoid pharmacology has been intensely studied because of cannabis' pervasive medicinal and non-medicinal uses as well as for the therapeutic potential of cannabinoid-based drugs for the treatment of pain, anxiety, substance abuse, obesity, cancer and neurodegenerative disorders. |
2018-05-09 |
2023-08-13 |
Not clear |
| R M Murray, A Englund, A Abi-Dargham, D A Lewis, M Di Forti, C Davies, M Sherif, P McGuire, D C D'Souz. Cannabis-associated psychosis: Neural substrate and clinical impact. Neuropharmacology. vol 124. 2018-05-09. PMID:28634109. |
early onset of use, daily use of high-potency cannabis, and synthetic cannabinoids carry the greatest risk. |
2018-05-09 |
2023-08-13 |
human |
| R M Murray, A Englund, A Abi-Dargham, D A Lewis, M Di Forti, C Davies, M Sherif, P McGuire, D C D'Souz. Cannabis-associated psychosis: Neural substrate and clinical impact. Neuropharmacology. vol 124. 2018-05-09. PMID:28634109. |
we are beginning to understand how cannabis use impacts on the endocannabinoid system but there is much still to learn about the biological mechanisms underlying how cannabis increases risk of psychosis. |
2018-05-09 |
2023-08-13 |
human |
| Sebastian Rojek, Małgorzata Kłys, Martyna Maciów-Głąb, Karol Kul. A new challenge in forensic toxicology exemplified by a case of murder under the influence of a synthetic cannabinoid - AM-2201. Legal medicine (Tokyo, Japan). vol 27. 2018-05-09. PMID:28668480. |
among new psychoactive substances (nps) available on the narcotic market, a significant number consists of synthetic cannabinoids commonly known as smokable herbal "spice" and "k2", and which are legally treated as a legal alternative to marijuana. |
2018-05-09 |
2023-08-13 |
human |
| Amy L Patton, Kathryn A Seely, Azure L Yarbrough, William Fantegrossi, Laura P James, Keith R McCain, Ryoichi Fujiwara, Paul L Prather, Jeffery H Moran, Anna Radominska-Pandy. Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants. Biochemical and biophysical research communications. vol 498. issue 3. 2018-05-03. PMID:29522717. |
synthetic cannabinoids (scbs), synonymous with 'k2', 'spice' or 'synthetic marijuana', are psychoactive drugs of abuse that frequently result in clinical effects and toxicity more severe than those classically associated with Δ |
2018-05-03 |
2023-08-13 |
human |
| b' Ana Lucia Arellano, Esther Papaseit, Anna Romaguera, Marta Torrens, Magi Farr\\xc3\\xa. Neuropsychiatric and General Interactions of Natural and Synthetic Cannabinoids with Drugs of Abuse and Medicines. CNS & neurological disorders drug targets. vol 16. issue 5. 2018-05-01. PMID:28412920.' |
the two most important natural cannabinoids are delta-9-tetrahydrocannabinol (thc) and cannabidiol (cbd). |
2018-05-01 |
2023-08-13 |
human |
| b' Ana Lucia Arellano, Esther Papaseit, Anna Romaguera, Marta Torrens, Magi Farr\\xc3\\xa. Neuropsychiatric and General Interactions of Natural and Synthetic Cannabinoids with Drugs of Abuse and Medicines. CNS & neurological disorders drug targets. vol 16. issue 5. 2018-05-01. PMID:28412920.' |
the thc content of cannabis has been increasing during the last years and recently appeared in the market as a series of synthetic cannabinoids with potent agonist activity. |
2018-05-01 |
2023-08-13 |
human |
| Linda M Console-Bram, Pingwei Zhao, Mary E Aboo. Protocols and Good Operating Practices in the Study of Cannabinoid Receptors. Methods in enzymology. vol 593. 2018-04-26. PMID:28750805. |
reproducibility among laboratories is especially important due to the development of novel tools to investigate the role(s) of the endocannabinoid system in human physiology, and to clarify the roles for medicinal marijuana. |
2018-04-26 |
2023-08-13 |
human |
| David Baker, Gareth Pryce, Cristina Visintin, Sofia Sisay, Alexander I Bondarenko, W S Vanessa Ho, Samuel J Jackson, Thomas E Williams, Sarah Al-Izki, Ioanna Sevastou, Masahiro Okuyama, Wolfgang F Graier, Lesley A Stevenson, Carolyn Tanner, Ruth Ross, Roger G Pertwee, Christopher M Henstridge, Andrew J Irving, Jesse Schulman, Keith Powell, Mark D Baker, Gavin Giovannoni, David L Selwoo. Big conductance calcium-activated potassium channel openers control spasticity without sedation. British journal of pharmacology. vol 174. issue 16. 2018-04-23. PMID:28677901. |
our initial aim was to generate cannabinoid agents that control spasticity, occurring as a consequence of multiple sclerosis (ms), whilst avoiding the sedative side effects associated with cannabis. |
2018-04-23 |
2023-08-13 |
Not clear |
| Ewa Kozela, Ana Juknat, Zvi Voge. Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid. International journal of molecular sciences. vol 18. issue 8. 2018-04-23. PMID:28788104. |
modulation of astrocyte activity by cannabidiol, a nonpsychoactive cannabinoid. |
2018-04-23 |
2023-08-13 |
Not clear |
| Ewa Kozela, Ana Juknat, Zvi Voge. Modulation of Astrocyte Activity by Cannabidiol, a Nonpsychoactive Cannabinoid. International journal of molecular sciences. vol 18. issue 8. 2018-04-23. PMID:28788104. |
cannabidiol (cbd) is the main non-psychotomimetic cannabinoid derived from |
2018-04-23 |
2023-08-13 |
Not clear |
| L Koenders, V Lorenzetti, L de Haan, C Suo, Wam Vingerhoets, W van den Brink, R W Wiers, C J Meijer, Mwj Machielsen, A E Goudriaan, D J Veltman, M Yücel, J Cousij. Longitudinal study of hippocampal volumes in heavy cannabis users. Journal of psychopharmacology (Oxford, England). vol 31. issue 8. 2018-04-20. PMID:28741422. |
cannabis exposure, particularly heavy cannabis use, has been associated with neuroanatomical alterations in regions rich with cannabinoid receptors such as the hippocampus in some but not in other (mainly cross-sectional) studies. |
2018-04-20 |
2023-08-13 |
Not clear |
| Ruth E Cooper, Emma Williams, Seth Seegobin, Charlotte Tye, Jonna Kuntsi, Philip Asherso. Cannabinoids in attention-deficit/hyperactivity disorder: A randomised-controlled trial. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 27. issue 8. 2018-04-18. PMID:28576350. |
while not definitive, this study provides preliminary evidence supporting the self-medication theory of cannabis use in adhd and the need for further studies of the endocannabinoid system in adhd. |
2018-04-18 |
2023-08-13 |
human |
| Gábor Nagy-Grócz, Ferenc Zádor, Szabolcs Dvorácskó, Zsuzsanna Bohár, Sándor Benyhe, Csaba Tömböly, Árpád Párdutz, László Vécse. Interactions between the Kynurenine and the Endocannabinoid System with Special Emphasis on Migraine. International journal of molecular sciences. vol 18. issue 8. 2018-04-17. PMID:28758944. |
the interaction of the endocannabinoid and kynurenine system has been demonstrated to be therapeutically relevant in a number of pathological conditions, such as cannabis addiction, psychosis, schizophrenia and epilepsy. |
2018-04-17 |
2023-08-13 |
Not clear |
| Eric Murillo-Rodriguez, Jose Carlos Pastrana-Trejo, Mireille Salas-Crisóstomo, Miriel de-la-Cru. The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents. CNS & neurological disorders drug targets. vol 16. issue 4. 2018-04-16. PMID:28240187. |
cannabinoids are derivatives that are either compounds occurring naturally in the plant, cannabis sativa or synthetic analogs of these molecules. |
2018-04-16 |
2023-08-13 |
mouse |
| Eric Murillo-Rodriguez, Jose Carlos Pastrana-Trejo, Mireille Salas-Crisóstomo, Miriel de-la-Cru. The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents. CNS & neurological disorders drug targets. vol 16. issue 4. 2018-04-16. PMID:28240187. |
the first and most widely investigated of the cannabinoids is Δ9-tetrahydrocannabinol (Δ9-thc), which is the main psychotropic constituent of cannabis and undergoes significant binding to cannabinoid receptors. |
2018-04-16 |
2023-08-13 |
mouse |
| Brian D Klein, Catherine A Jacobson, Cameron S Metcalf, Misty D Smith, Karen S Wilcox, Aidan J Hampson, John H Kehn. Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP). Neurochemical research. vol 42. issue 7. 2018-04-16. PMID:28478594. |
cannabidiol (cbd) is a cannabinoid component of marijuana that has no significant activity at cannabinoid receptors or psychoactive effects. |
2018-04-16 |
2023-08-13 |
mouse |
| Nicholas Pintori, Barbara Loi, Maddalena Mere. Synthetic cannabinoids: the hidden side of Spice drugs. Behavioural pharmacology. vol 28. issue 6. 2018-04-16. PMID:28692429. |
spice drugs are herbal mixtures sprayed with synthetic cannabinoids designed to mimic the psychoactive ingredient in marijuana [Δ-tetrahydrocannabinol (Δ-thc)] and synthesized by introducing modifications to the chemical structure of parental compounds aiming to circumvent legal regulations. |
2018-04-16 |
2023-08-13 |
Not clear |