| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pu-Qing Yuan, Hong Yan. Neuronal activation of brain vagal-regulatory pathways and upper gut enteric plexuses by insulin hypoglycemia. American journal of physiology. Endocrinology and metabolism. vol 283. issue 3. 2002-09-23. PMID:12169436. |
a substantial number of insulin hypoglycemia-activated dmn and nts neurons were choline acetyltransferase and tyrosine hydroxylase positive, respectively, whereas the activated enteric neurons included nadph- and vasoactive intestinal peptide neurons. |
2002-09-23 |
2023-08-12 |
rat |
| Carol Hamelink, Olga Tjurmina, Ruslan Damadzic, W Scott Young, Eberhard Weihe, Hyeon-Woo Lee, Lee E Eide. Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 1. 2002-04-15. PMID:11756684. |
failure of pacap-deficient mice to adequately counterregulate plasma glucose levels could be accounted for by impaired long-term secretion of epinephrine, secondary to a lack of induction of tyrosine hydroxylase, normally occurring after insulin hypoglycemia in wild-type mice, and a consequent depletion of adrenomedullary epinephrine stores. |
2002-04-15 |
2023-08-12 |
mouse |
| G Paolisso, M Barbieri, M R Rizzo, C Carella, M Rotondi, M Bonafè, C Franceschi, G Rose, G De Benedicti. Low insulin resistance and preserved beta-cell function contribute to human longevity but are not associated with TH-INS genes. Experimental gerontology. vol 37. issue 1. 2002-02-25. PMID:11738155. |
tyrosine hydroxylase (th) and insulin (ins) genes lie extremely close in the 11p15.5 chromosomal region. |
2002-02-25 |
2023-08-12 |
human |
| C L Barr, L Best, R Weksber. Linkage study in families with posterior helical ear pits and Wiedemann-Beckwith syndrome. American journal of medical genetics. vol 104. issue 2. 2002-02-14. PMID:11746041. |
these three markers were in the insulin-like growth factor (igf2), insulin (ins), and tyrosine hydroxylase (th) region. |
2002-02-14 |
2023-08-12 |
Not clear |
| S Persson-Sjögren, S Forsgren, C L Shi, I B Täljeda. Mouse islets cultured with vasoactive intestinal polypeptide: effects on insulin release and immunoreactivity for tyrosine hydroxylase. Pancreas. vol 22. issue 1. 2001-02-15. PMID:11138978. |
mouse islets cultured with vasoactive intestinal polypeptide: effects on insulin release and immunoreactivity for tyrosine hydroxylase. |
2001-02-15 |
2023-08-12 |
mouse |
| S Persson-Sjögren, S Forsgren, C L Shi, I B Täljeda. Mouse islets cultured with vasoactive intestinal polypeptide: effects on insulin release and immunoreactivity for tyrosine hydroxylase. Pancreas. vol 22. issue 1. 2001-02-15. PMID:11138978. |
mouse islets cultured for 1 or 4 days with or without 10 nm vasoactive intestinal polypeptide (vip) were stained for tyrosine hydroxylase (th) and examined for insulin secretion during culture and in a postculture perifusion system. |
2001-02-15 |
2023-08-12 |
mouse |
| M Chiba, S Suzuki, Y Hinokio, M Hirai, Y Satoh, A Tashiro, A Utsumi, T Awata, M Hongo, T Toyot. Tyrosine hydroxylase gene microsatellite polymorphism associated with insulin resistance in depressive disorder. Metabolism: clinical and experimental. vol 49. issue 9. 2000-10-12. PMID:11016895. |
tyrosine hydroxylase gene microsatellite polymorphism associated with insulin resistance in depressive disorder. |
2000-10-12 |
2023-08-12 |
human |
| M Chiba, S Suzuki, Y Hinokio, M Hirai, Y Satoh, A Tashiro, A Utsumi, T Awata, M Hongo, T Toyot. Tyrosine hydroxylase gene microsatellite polymorphism associated with insulin resistance in depressive disorder. Metabolism: clinical and experimental. vol 49. issue 9. 2000-10-12. PMID:11016895. |
to determine whether the genetic polymorphisms of the tyrosine hydroxylase ([th] humth01) and insulin (ins-vntr) genes contribute to insulin resistance in depressive illness, we analyzed the association between the polymorphisms and insulin resistance in 41 japanese patients with depressive disorder, 204 normal control subjects, 161 cohort subjects with normal glucose tolerance (ngt) and without depressive symptomatology, and 59 ngt subjects with depressive symptomatology. |
2000-10-12 |
2023-08-12 |
human |
| b' M Rusn\\xc3\\xa1k, J Jelokov\\xc3\\xa1, I Vietor, E L Sabban, R Kvetnansk\\xc3\\xb. Different effects of insulin and 2-deoxy-D-glucose administration on tyrosine hydroxylase gene expression in the locus coeruleus and the adrenal medulla in rats. Brain research bulletin. vol 46. issue 5. 1998-11-30. PMID:9739008.' |
different effects of insulin and 2-deoxy-d-glucose administration on tyrosine hydroxylase gene expression in the locus coeruleus and the adrenal medulla in rats. |
1998-11-30 |
2023-08-12 |
rat |
| C Collet, J Candy, V Sar. Tyrosine hydroxylase and insulin-like growth factor II but not insulin are adjacent in the teleost species barramundi, Lates calcarifer. Animal genetics. vol 29. issue 1. 1998-08-25. PMID:9682446. |
tyrosine hydroxylase and insulin-like growth factor ii but not insulin are adjacent in the teleost species barramundi, lates calcarifer. |
1998-08-25 |
2023-08-12 |
Not clear |
| C Collet, J Candy, V Sar. Tyrosine hydroxylase and insulin-like growth factor II but not insulin are adjacent in the teleost species barramundi, Lates calcarifer. Animal genetics. vol 29. issue 1. 1998-08-25. PMID:9682446. |
in humans, the genes encoding tyrosine hydroxylase (th), insulin and insulin-like growth factor ii (igf-ii) form an extremely tight linkage group on chromosome 11p15. |
1998-08-25 |
2023-08-12 |
Not clear |
| I Vietor, M Rusnak, E Viskupic, P Blazicek, E L Sabban, R Kvetnansk. Glucoprivation by insulin leads to trans-synaptic increase in rat adrenal tyrosine hydroxylase mRNA levels. European journal of pharmacology. vol 313. issue 1-2. 1997-02-27. PMID:8905338. |
a significant increase (3-5-fold) in tyrosine hydroxylase mrna levels was found at 5 h, decreasing to near basal levels at 24 h following the first and also the sixth consecutive injection of insulin or 2-deoxy-d-glucose. |
1997-02-27 |
2023-08-12 |
rat |
| I Vietor, M Rusnak, E Viskupic, P Blazicek, E L Sabban, R Kvetnansk. Glucoprivation by insulin leads to trans-synaptic increase in rat adrenal tyrosine hydroxylase mRNA levels. European journal of pharmacology. vol 313. issue 1-2. 1997-02-27. PMID:8905338. |
western blot analysis showed that although a single insulin treatment did not affect tyrosine hydroxylase protein levels, a significant increase was observed following the seventh administration. |
1997-02-27 |
2023-08-12 |
rat |
| I Vietor, M Rusnak, E Viskupic, P Blazicek, E L Sabban, R Kvetnansk. Glucoprivation by insulin leads to trans-synaptic increase in rat adrenal tyrosine hydroxylase mRNA levels. European journal of pharmacology. vol 313. issue 1-2. 1997-02-27. PMID:8905338. |
glucoprivation by insulin leads to trans-synaptic increase in rat adrenal tyrosine hydroxylase mrna levels. |
1997-02-27 |
2023-08-12 |
rat |
| I Vietor, M Rusnak, E Viskupic, P Blazicek, E L Sabban, R Kvetnansk. Glucoprivation by insulin leads to trans-synaptic increase in rat adrenal tyrosine hydroxylase mRNA levels. European journal of pharmacology. vol 313. issue 1-2. 1997-02-27. PMID:8905338. |
whereas insulin treatment raised tyrosine hydroxylase mrna levels in intact adrenals, no increase in tyrosine hydroxylase mrna levels occurred following adrenal denervation by splanchnic nerve transection. |
1997-02-27 |
2023-08-12 |
rat |
| I Vietor, M Rusnak, E Viskupic, P Blazicek, E L Sabban, R Kvetnansk. Glucoprivation by insulin leads to trans-synaptic increase in rat adrenal tyrosine hydroxylase mRNA levels. European journal of pharmacology. vol 313. issue 1-2. 1997-02-27. PMID:8905338. |
effects of single or repeated insulin or 2-deoxy-d-glucose administration on adrenal tyrosine hydroxylase mrna and protein levels were examined in rats. |
1997-02-27 |
2023-08-12 |
rat |
| B Ahrén, E Simonsson, A J Scheurink, H Mulder, U Myrsén, F Sundle. Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice. Metabolism: clinical and experimental. vol 46. issue 1. 1997-02-13. PMID:9005977. |
moreover, islet morphology as examined by immunocytochemistry using insulin antibodies and islet innervation, as revealed by immunostaining of tyrosine hydroxylase (th), neuropeptide y (npy), galanin, vasoactive intestinal polypeptide (vip), and substance p (sp) were unaffected by the high-fat diet for 12 weeks. |
1997-02-13 |
2023-08-12 |
mouse |
| G J Kantor, D M Deiss-Tolber. Identification of a large genomic region in UV-irradiated human cells which has fewer cyclobutane pyrimidine dimers than most genomic regions. Photochemistry and photobiology. vol 62. issue 2. 1995-11-28. PMID:7480136. |
three contiguous genes located in a g+c-rich isochore (tyrosine hydroxylase, insulin, insulin-like growth factor ii) have concentrations two to three times greater in the largest molecules. |
1995-11-28 |
2023-08-12 |
human |
| D E Undlien, S T Bennett, J A Todd, H E Akselsen, I Ikäheimo, H Reijonen, M Knip, E Thorsby, K S Rønninge. Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene. Diabetes. vol 44. issue 6. 1995-07-24. PMID:7789624. |
the vntr is located adjacent to defined regulatory dna sequences affecting insulin gene expression, which suggests a possible effect on expression of insulin or one of the neighboring genes, tyrosine hydroxylase or insulin-like growth factor 2. |
1995-07-24 |
2023-08-12 |
human |
| A J Portis, R V Rajotte, T L Krukof. Reinnervation of isolated islets of Langerhans transplanted beneath the kidney capsule in the rat. Cell transplantation. vol 3. issue 2. 1994-07-28. PMID:7912158. |
antibodies were directed against (a) neuron associated proteins: synapsin (syn) and l1; (b) neurotransmitters; tyrosine hydroxylase (th), neuropeptide y (npy), vasoactive intestinal peptide (vip), and calcitonin gene-related peptide (cgrp); and (c) islet hormones: insulin and somatostatin. |
1994-07-28 |
2023-08-12 |
rat |