| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nagmi Bano, Shaban Ahmad, Dinesh Gupta, Khalid Raz. FDA-approved Levophed as an alternative multitargeted therapeutic against cervical cancer transferase, cell cycle, and regulatory proteins. Computers in biology and medicine. vol 191. 2025-04-10. PMID:40209578. |
the protein residues that interact the most with levophed are ala, thr, ile, asn, gly, asp, leu, lys, val, gln, pro, cys, glu, and tyr. |
2025-04-10 |
2025-04-14 |
Not clear |
| Ernest Oduro-Kwateng, Ibrahim Oluwatobi Kehinde, Musab Ali, Kabange Kasumbwe, Vuyisa Mzozoyana, Narasimham L Parinandi, Mahmoud E S Solima. Computational Analysis of Plasmodium falciparum DNA Damage Inducible Protein 1 (PfDdi1): Insights into Binding of Artemisinin and its Derivatives and Implications for Antimalarial Drug Design. Cell biochemistry and biophysics. 2025-03-21. PMID:40113723. |
importantly, three key binding regions-loop 1 (gln 266 - ile 269), loop 2 (ile 323 - tyr 326), and loop 3 (ala 292 - gly 294)-were identified as potential targets for new antimalarial drugs against pfddi1. |
2025-03-21 |
2025-03-23 |
human |
| Shaban Ahmad, Nagmi Bano, Khalid Raz. Evaluating the polypharmacological potency of FEDPN from ChEMBL BioAssays against lung cancer EGFR, ALK, TrkA and KRAS proteins. International journal of biological macromolecules. 2025-03-05. PMID:40043981. |
we also evaluated the results with mifs, which identified val, glu, gly, leu, lys, thr, and tyr as the most interacted residues. |
2025-03-05 |
2025-03-08 |
Not clear |
| Roylan Pais, Anil Kumar Nagraj, Riya Patel, Akshata Gavade, Mohasin Momin, Juergen Scheele, Werner Seiz, Jaspal Pati. Amino Acids Frequency and Interaction Trends: Comprehensive Analysis of Experimentally Validated Viral Antigen-Antibody Complexes. Molecular biotechnology. 2025-01-08. PMID:39775710. |
the finding revealed that ser, gly, tyr, thr, and phe are prominently present in the antibody cdrs. |
2025-01-08 |
2025-01-13 |
human |
| Bingqi Gao, Yue Ao, Zhengzheng Zhao, Zhicheng Wang, Chongrui Yang, Minmin Cai, Chan Y. Characteristics and biological mechanism of protein degradation by the black solider fly (Hermetia illucens L.) larvae gut strain Bacillus subtilis S4. Food chemistry. vol 464. issue Pt 3. 2024-11-13. PMID:39536587. |
in vitro high-performance liquid chromatography analysis showed that b. subtilis s4 completely degraded casein into val, ile, phe, leu, tyr, lys, gly, and met. |
2024-11-13 |
2024-11-17 |
Not clear |
| H Sadri, M H Ghaffari, H Sauerwein, S Schuchardt, J Martín-Tereso, John Doelman, J B Danie. Longitudinal characterization of the muscle metabolome in dairy cows during the transition from lactation cessation to lactation resumption. Journal of dairy science. 2024-09-29. PMID:39343201. |
this coincided with an increase in the concentrations of 11 aa (phe, his, tyr, trp, arg, asn, leu, ile, gly, ser, and thr) in the first wk after calving, whereas gln decreased. |
2024-09-29 |
2024-10-02 |
Not clear |
| Chiaki Kuroda, Kensei Kobayash. Alkylation of Complex Glycine Precursor (CGP) as a Prebiotic Route to 20 Proteinogenic Amino Acids Synthesis. Molecules (Basel, Switzerland). vol 29. issue 18. 2024-09-28. PMID:39339398. |
the scenario consists of three stages: a high-energy reaction stage (gly, ala, asn, and asp were established); an alkylation stage (gln, glu, ser, thr, val, ile, leu, and pro were generated in considerable amounts); and a peptide formation stage (phe, tyr, trp, his, lys, arg, cys, and met were selected due to their structural advantages). |
2024-09-28 |
2024-10-01 |
Not clear |
| Tze-Fei Won. Triphasic Development of the Genetic Code. Chemical reviews. 2024-08-01. PMID:39088192. |
the ten phase 1 amino acids, including gly, ala, ser, asp, glu, val, leu, ile, pro and thr, were available from the prebiotic environment, whereas the ten phase 2 amino acids, including phe, tyr, arg, his, trp, asn, gln, lys, cys, and met, became available only later from amino acid biosyntheses. |
2024-08-01 |
2024-08-03 |
Not clear |
| Riho Kimura, Shotaro Hashimoto, Hiroaki Eguchi, Yoshifumi Morikawa, Koichi Suenami, Yuta Yoshino, Toshiyuki Matsunaga, Satoshi Endo, Akira Ikar. Enhancement of chemoresistance by claudin-1-mediated formation of amino acid barriers in human lung adenocarcinoma A549 cells. Archives of biochemistry and biophysics. 2024-07-27. PMID:39067558. |
the paracellular aa flux except for ser, thr, tyr, ala, and gly was enhanced by cldn1 silencing. |
2024-07-27 |
2024-08-02 |
human |
| Mengmeng Sun, Annelies De Cuyper, Guido Bosch, Ellen S Dierenfeld, Wouter H Hendriks, Geert P J Janssen. Protein quality of a small mammal prey and its body organs for felids. Journal of animal science. 2024-07-09. PMID:38980729. |
in bone, the digestibility spanned from 56.9% for gly to 81.1% for tyrosine (tyr). |
2024-07-09 |
2024-07-12 |
rat |
| Lyudmila V Bel'skaya, Elena A Sarf, Denis V Solomati. Free Salivary Amino Acid Profile in Breast Cancer: Clinicopathological and Molecular Biological Features. Current issues in molecular biology. vol 46. issue 6. 2024-06-26. PMID:38921007. |
statistically significant differences between the three groups are shown in the content of asp, gly, leu + ile, orn, phe, pro, thr, and tyr. |
2024-06-26 |
2024-06-29 |
Not clear |
| Jianan Liu, Junya Zhu, Hongshun Hao, Jingran Bi, Hongman Hou, Gongliang Zhan. Transcriptomic and Molecular Docking Analysis Reveal Virulence Gene Regulation-Mediated Antibacterial Effects of Benzyl Isothiocyanate Against Staphylococcus aureus. Applied biochemistry and biotechnology. 2024-05-06. PMID:38709426. |
bitc forms hydrophobic, hydrogen-bonded, π-π conjugated interactions with amino acids trp (130), gly (10), ile (406), lys (368), tyr (192), and arg (114) of these proteins. |
2024-05-06 |
2024-05-08 |
Not clear |
| Isabella Moppel, BarbaraAnn Elliott, Shuming Che. Intermolecular hydrogen bonding behavior of amino acid radical cations. Organic & biomolecular chemistry. 2024-05-01. PMID:38690804. |
using density functional theory (dft) calculations at the ωb97x-d/def2-qzvppd//ωb97x-d/def2-tzvpp level of theory, we systematically investigated the hydrogen bonding between water and fourteen α-amino acids (ala, asn, cys, gln, gly, his, met, phe, pro, sel, ser, thr, trp, and tyr) in both neutral and radical cation forms. |
2024-05-01 |
2024-05-04 |
Not clear |
| Sahayog N Jamdar, Pooja Yadav, Bhushan S Kulkarni, Sudesh, Ashwani Kumar, Ravindra D Makd. Crystal structure of a newly identified M61 family aminopeptidase with broad substrate specificity that is solely responsible for recycling acidic amino acids. The FEBS journal. 2024-04-22. PMID:38646733. |
the enzyme exhibits broad specificity and cleaves ala, leu, asp, glu, met, ser, phe, tyr, gly, arg, and lys at the n terminus, optimally of peptides with a length of 3-7 amino acids. |
2024-04-22 |
2024-04-24 |
Not clear |
| Zoya Shafat, Asimul Islam, Shama Parvee. Amino acid pattern reveals multi-functionality of ORF3 protein from HEV. Bioinformation. vol 20. issue 2. 2024-03-18. PMID:38497081. |
amino acid distribution showed orf3 enrichment with disorder-promoting residues (ala, pro, ser, gly) while deficiency in order-promoting residues (asn, ile, phe, tyr and trp). |
2024-03-18 |
2024-03-20 |
Not clear |
| Hassan Safari, Ardeshir Mohit, Maziar Mohiti-Asl. Feather meal processing methods impact the production parameters, blood biochemical indices, gut function, and hepatic enzyme activity in broilers. Journal of animal science. 2024-03-13. PMID:38477705. |
results showed that in the ffms the contents of ash, ether extract, total volatile nitrogen, and amino acids including lys, met, thr, trp, his, leu, gly, ile, phe, and tyr increased (p < 0.05), while crude fiber, crude protein, and dry matter content decreased (p < 0.05). |
2024-03-13 |
2024-03-15 |
Not clear |
| Na Li, Shengchao Lin, Wenjia Sun, Min Xu, Ping Liu, Zhenming Ch. Application effects of NaCl substitute on the fermentation profile of Pixian douban (broad bean paste). Journal of food science. 2024-03-11. PMID:38465700. |
correlation analysis showed that glu, phe, tyr, gly, leu, val, asp, ile, citric acids, and succinic acids were all positively correlated with the main aroma and contributed to the generation of pxdb's characteristic flavor, and main aroma substances in turn positively influence pxdb flavor sensory attributes. |
2024-03-11 |
2024-03-14 |
Not clear |
| Preeti Pandey, Emil Alexo. Most Monogenic Disorders Are Caused by Mutations Altering Protein Folding Free Energy. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38396641. |
also, mutations involving cys, gly, arg, trp, and tyr amino acids being replaced by any other amino acid are more likely to be pathogenic. |
2024-02-24 |
2024-02-26 |
Not clear |
| Fida Bacha, Heba El-Ayash, Mahmoud Mohamad, Susan Sharma, Maurice Puyau, Rupa Kanchi, Cristian Coarf. Distinct Amino Acid Profile Characterizes Youth with or at risk for Type 2 Diabetes. Diabetes. 2024-01-12. PMID:38215171. |
our results showed that gly and gln/glu were lower, whereas bcaa, tyr and lys concentrations were higher in the groups with obesity and dysglycemia compared with those with normal weight. |
2024-01-12 |
2024-01-15 |
Not clear |
| Mohammed Ageeli Hakami, Ali Hazazi, Fawaz Albloui, Amal F Gharib, Fouzeyyah Ali Alsaeedi, Osama Abdulaziz, Abdulfattah Y Alhazmi, Ahad Amer Alsaiar. Delineated 3-1-BenCarMethInYlPro-Phosphonic Acid's Adroit Activity against Lung Cancer through Multitargeted Docking, MM\GBSA, QM-DFT and Multiscale Simulations. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203761. |
further, the pharmacokinetic and qm-based dft studies have shown complete acceptance results, and interaction fingerprinting reveals that ile, gly, val, tyr, leu, and gln were among the most interacting residues. |
2024-01-11 |
2024-01-13 |
Not clear |