| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yvonne K Van Pareren, Sabine M P F De Muinck Keizer-Schrama, Theo Stijnen, Theo C J Sas, Stenvert L S Dro. Effect of discontinuation of long-term growth hormone treatment on carbohydrate metabolism and risk factors for cardiovascular disease in girls with Turner syndrome. The Journal of clinical endocrinology and metabolism. vol 87. issue 12. 2003-01-17. PMID:12466334. |
in conclusion, after discontinuation of long-term gh treatment in girls with ts, the gh-induced insulin resistance disappeared, blood pressure decreased but remained higher than in the normal population, and lipid levels and the ai changed to more cardio-protective values. |
2003-01-17 |
2023-08-12 |
Not clear |
| Y Ozkul, T Sabuncu, P Yazgan, Y Nazligu. Local insulin injection improves median nerve regeneration in NIDDM patients with carpal tunnel syndrome. European journal of neurology. vol 8. issue 4. 2001-08-16. PMID:11422429. |
therefore, we aimed to evaluate the effectiveness of local insulin injection on median nerve in patients with non-insulin-dependent diabetes (niddm) mellitus who have mild-to-moderate carpal tunnel syndrome (ts). |
2001-08-16 |
2023-08-12 |
Not clear |
| T C Sas, S M de Muinck Keizer-Schrama, T Stijnen, H J Aanstoot, S L Dro. Carbohydrate metabolism during long-term growth hormone (GH) treatment and after discontinuation of GH treatment in girls with Turner syndrome participating in a randomized dose-response study. Dutch Advisory Group on Growth Hormone. The Journal of clinical endocrinology and metabolism. vol 85. issue 2. 2000-03-09. PMID:10690889. |
in conclusion, long term gh treatment with dosages up to 8 iu/m2 x day in girls with ts has no adverse effects on glucose levels, but induced higher levels of insulin, indicating relative insulin resistance. |
2000-03-09 |
2023-08-12 |
Not clear |
| T Miura, M Noda, T Fukunaga, K Furut. Hypoglycemic activity of to-kai-san (Chinese medicines) in normal and KK-Ay mice. Journal of nutritional science and vitaminology. vol 43. issue 1. 1997-08-26. PMID:9151237. |
from these findings, it is believed that ts may require the presence of insulin to display its activity. |
1997-08-26 |
2023-08-12 |
mouse |
| G Haeusler, K Schmitt, P Blümel, E Plöchl, T Waldhör, H Frisc. Insulin, insulin-like growth factor-binding protein-1, and sex hormone-binding globulin in patients with Turner's syndrome: course over age in untreated patients and effect of therapy with growth hormone alone and in combination with oxandrolone. The Journal of clinical endocrinology and metabolism. vol 81. issue 2. 1996-07-08. PMID:8636264. |
we have studied the course over age of fasting insulin, sex hormone-binding globulin (shbg), and insulin-like growth factor (igf)-binding protein-1 (igfbp-1) in untreated children with turner's syndrome (ts) and measured the course of these parameters during therapy with gh alone and in combination with oxandrolone. |
1996-07-08 |
2023-08-12 |
Not clear |
| G Haeusler, K Schmitt, P Blümel, E Plöchl, T Waldhör, H Frisc. Insulin, insulin-like growth factor-binding protein-1, and sex hormone-binding globulin in patients with Turner's syndrome: course over age in untreated patients and effect of therapy with growth hormone alone and in combination with oxandrolone. The Journal of clinical endocrinology and metabolism. vol 81. issue 2. 1996-07-08. PMID:8636264. |
shbg and igfbp-1 were not coregulated by insulin in ts as previously reported under physiological conditions; igfbp-1 was inversely correlated with insulin, but shbg was not, and neither parameter was correlated with the other. |
1996-07-08 |
2023-08-12 |
Not clear |
| G Haeusler, K Schmitt, P Blümel, E Plöchl, T Waldhör, H Frisc. Insulin, insulin-like growth factor-binding protein-1, and sex hormone-binding globulin in patients with Turner's syndrome: course over age in untreated patients and effect of therapy with growth hormone alone and in combination with oxandrolone. The Journal of clinical endocrinology and metabolism. vol 81. issue 2. 1996-07-08. PMID:8636264. |
in conclusion, there were no abnormalities in serum concentrations of insulin, shbg, and igfbp-1 in untreated patients that could help to explain the retarded growth in patients with ts. |
1996-07-08 |
2023-08-12 |
Not clear |
| G Haeusler, K Schmitt, P Blümel, E Plöchl, T Waldhör, H Frisc. Insulin, insulin-like growth factor-binding protein-1, and sex hormone-binding globulin in patients with Turner's syndrome: course over age in untreated patients and effect of therapy with growth hormone alone and in combination with oxandrolone. The Journal of clinical endocrinology and metabolism. vol 81. issue 2. 1996-07-08. PMID:8636264. |
our data confirm the importance of insulin in the regulation of igfbp-1, but do not point to a coregulation of igfbp-1 and shbg by insulin in patients with ts. |
1996-07-08 |
2023-08-12 |
Not clear |
| R P Hoffma. Insulin antagonistic effects of growth hormone in short children. Hormone research. vol 44. issue 5. 1996-03-21. PMID:8582710. |
to determine the time course of these effects in growth-hormone-treated children, the frequently samples intravenous glucose tolerance test was used to measure insulin sensitivity (si) and glucose effectiveness (sg) before, and 1 week, 1 month and 6 months after beginning growth hormone therapy in 3 patients with growth hormone deficiency (ghd), 3 patients with non-growth-hormone-deficient short stature (nghd) and 3 with turner syndrome (ts). |
1996-03-21 |
2023-08-12 |
Not clear |
| b' B Costa, A Estop\\xc3\\xa1, J Borr\\xc3\\xa1s, A Sabat\\xc3\\xa. [Diabetes and pharmacoeconomics. Efficiency of insulin injection methods available in Spain]. Atencion primaria. vol 16. issue 7. 1996-01-16. PMID:7495947.' |
in spain today there are three ways of injecting insulin, the traditional syringe (ts) and two automatic methods: injector pens (ip) and preloaded syringes (ps). |
1996-01-16 |
2023-08-12 |
Not clear |
| F Vaccaro, S Cianfarani, A M Pasquino, B Boscherin. Is obesity-related insulin status the cause of blunted growth hormone secretion in Turner's syndrome? Metabolism: clinical and experimental. vol 44. issue 8. 1995-09-12. PMID:7637644. |
in the present study, we assessed the influence of overweight-related insulin status on spontaneous gh secretion in a group of 15 ts girls. |
1995-09-12 |
2023-08-12 |
human |
| F Vaccaro, S Cianfarani, A M Pasquino, B Boscherin. Is obesity-related insulin status the cause of blunted growth hormone secretion in Turner's syndrome? Metabolism: clinical and experimental. vol 44. issue 8. 1995-09-12. PMID:7637644. |
these results confirm that the blunted gh secretion in ts patients is dependent on nutritional status, and suggest that insulin resistance secondary to overweight might represent the pathophysiologic link between the obesity-related metabolic status and impaired gh secretion. |
1995-09-12 |
2023-08-12 |
human |
| P Amendt, V Hesse, W Rohd. Somatomedin-C/IGF-I, insulin and prolactin levels in Ullrich-Turner's syndrome. Experimental and clinical endocrinology. vol 99. issue 2. 1992-09-02. PMID:1639121. |
to clarify the pathogenesis of growth retardation in patients with ullrich-turner's syndrome (ts) we have investigated basal smc/igf-i, insulin and prolactin concentrations. |
1992-09-02 |
2023-08-11 |
Not clear |
| P Amendt, V Hesse, W Rohd. Somatomedin-C/IGF-I, insulin and prolactin levels in Ullrich-Turner's syndrome. Experimental and clinical endocrinology. vol 99. issue 2. 1992-09-02. PMID:1639121. |
basal insulin concentration in 28 ts patients in comparison to 20 healthy children of a control group was significant higher (ts 18 +/- 8 microu/ml; controls 9 +/- 4 microu/ml; p less than 0.01). |
1992-09-02 |
2023-08-11 |
Not clear |
| P Amendt, V Hesse, W Rohd. Somatomedin-C/IGF-I, insulin and prolactin levels in Ullrich-Turner's syndrome. Experimental and clinical endocrinology. vol 99. issue 2. 1992-09-02. PMID:1639121. |
considering these results we speculate that despite higher prolactin and higher insulin levels in ts, the lower smc/igf-i concentrations may be predominantly related to the abnormal sex steroid secretion. |
1992-09-02 |
2023-08-11 |
Not clear |
| R A Majack, S C Cook, P Bornstei. Control of smooth muscle cell growth by components of the extracellular matrix: autocrine role for thrombospondin. Proceedings of the National Academy of Sciences of the United States of America. vol 83. issue 23. 1987-01-14. PMID:3491367. |
the effect was specific for egf; ts did not augment the response of cells to insulin or insulin-like growth factor 1. |
1987-01-14 |
2023-08-11 |
human |
| N S Kartavova, N S Gutnik, D P Burlaka, O I Dasiukevic. [Estradiol and progesterone receptors in DMBA-induced mammary neoplasms in rats under cyclic hormonal exposures]. Eksperimental'naia onkologiia. vol 8. issue 1. 1986-04-09. PMID:3081323. |
a high level of er and pr and a high frequency of r+ tumours were observed after a successive administration of insulin, prednisolone, hpc and ts. |
1986-04-09 |
2023-08-11 |
rat |
| E A Sweeney, C S Juan, T W AvRuski. Turner's syndrome and carbohydrate metabolism. II. Parotid salivary insulin concentration in normal subjects and in patients with gonadal dysgenesis. The American journal of the medical sciences. vol 277. issue 2. 1979-09-25. PMID:463943. |
after tolbutamide, peak serum insulin concentrations were lower in the patients with turner's syndrome (ts) than in control siblings (58 +/- 10 vs 90 +/- 15 microu/ml) and fractional areas under insulin curves were significantly lower in the patients with turner's syndrome at 10 to 15 minutes (ts: 240 +/- 16 microumin/ml; cs: 340 +/- 46 microu-min/ml, p less than 0.05) and at 15 to 30 minutes (ts: 562 +/- 62 microu-min/ml; cs: 884 +/- 128 microu-min/ml, p less than 0.05). |
1979-09-25 |
2023-08-11 |
human |
| E A Sweeney, C S Juan, T W AvRuski. Turner's syndrome and carbohydrate metabolism. II. Parotid salivary insulin concentration in normal subjects and in patients with gonadal dysgenesis. The American journal of the medical sciences. vol 277. issue 2. 1979-09-25. PMID:463943. |
after glucagon, peak serum insulin concentrations were significantly lower in turner's syndrome than in control siblings(p less than 0.02, at 45 minutes) and fractional areas under insulin curves were also lower in ts than in siblings at 30 to 45 minutes (ts: 1,062 +/- 185 microu-min/ml; cs: 2,189 +/- 402 microu-min/ml, p less than 0.02). |
1979-09-25 |
2023-08-11 |
human |
| E A Sweeney, C S Juan, T W AvRuski. Turner's syndrome and carbohydrate metabolism. II. Parotid salivary insulin concentration in normal subjects and in patients with gonadal dysgenesis. The American journal of the medical sciences. vol 277. issue 2. 1979-09-25. PMID:463943. |
basal salivary immunoreactive insulin (ir) concentrations were similar in both groups: ts: 4.8 +/- 2.1 microu/min; cs: 2.1 +/- 0.4 microu/min. |
1979-09-25 |
2023-08-11 |
human |