| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Solange Travassos de Figueiredo Alves, Carla Tavares Gallichio, Marília Martins Guimarãe. Insulin resistance and body composition in Turner syndrome: Effect of sequential change in the route of estrogen administration. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 22. issue 10. 2007-02-28. PMID:17135039. |
we conclude that sequential change in the route of estrogen administration in ts patients using cyclical hrt with cee and mpa does not affect insulin resistance, although use of percutaneous 17beta-estradiol gel seems to exert favorable changes in body composition. |
2007-02-28 |
2023-08-12 |
Not clear |
| Laura Mazzanti, Rosalba Bergamaschi, Laura Castiglioni, Franco Zappulla, Piero Pirazzoli, Alessandro Cicognan. Turner syndrome, insulin sensitivity and growth hormone treatment. Hormone research. vol 64 Suppl 3. 2006-05-10. PMID:16439845. |
mild insulin resistance appears to be an early metabolic defect in girls with turner syndrome (ts). |
2006-05-10 |
2023-08-12 |
Not clear |
| Laura Mazzanti, Rosalba Bergamaschi, Laura Castiglioni, Franco Zappulla, Piero Pirazzoli, Alessandro Cicognan. Turner syndrome, insulin sensitivity and growth hormone treatment. Hormone research. vol 64 Suppl 3. 2006-05-10. PMID:16439845. |
in a mixed longitudinal and cross-sectional study, we analysed carbohydrate tolerance and insulin sensitivity in 46 children and adolescents with ts who reached their final height after long-term treatment (mean 6.3 +/- 2.5 years) with growth hormone (gh: 0.33 mg/kg/week [0.05 mg/kg/day]), and in 36 of these patients who were followed-up after the cessation of gh therapy (mean follow-up, 2.6 +/- 2.5 years; range, 1-9.5 years). |
2006-05-10 |
2023-08-12 |
Not clear |
| Laura Mazzanti, Rosalba Bergamaschi, Laura Castiglioni, Franco Zappulla, Piero Pirazzoli, Alessandro Cicognan. Turner syndrome, insulin sensitivity and growth hormone treatment. Hormone research. vol 64 Suppl 3. 2006-05-10. PMID:16439845. |
insulin sensitivity appeared to be lower in patients with ts than in controls, even before the start of gh therapy. |
2006-05-10 |
2023-08-12 |
Not clear |
| Laura Mazzanti, Rosalba Bergamaschi, Laura Castiglioni, Franco Zappulla, Piero Pirazzoli, Alessandro Cicognan. Turner syndrome, insulin sensitivity and growth hormone treatment. Hormone research. vol 64 Suppl 3. 2006-05-10. PMID:16439845. |
as in controls, insulin sensitivity decreased with age in patients with ts, and levels were lower in those aged >12 years than in those aged <12 years. |
2006-05-10 |
2023-08-12 |
Not clear |
| Laura Mazzanti, Rosalba Bergamaschi, Laura Castiglioni, Franco Zappulla, Piero Pirazzoli, Alessandro Cicognan. Turner syndrome, insulin sensitivity and growth hormone treatment. Hormone research. vol 64 Suppl 3. 2006-05-10. PMID:16439845. |
we therefore report a progressive improvement in carbohydrate tolerance and insulin function in patients with ts, despite an increase in age. |
2006-05-10 |
2023-08-12 |
Not clear |
| Burak Salgin, Rakesh Amin, Kevin Yuen, Rachel M Williams, Peter Murgatroyd, David B Dunge. Insulin resistance is an intrinsic defect independent of fat mass in women with Turner's syndrome. Hormone research. vol 65. issue 2. 2006-04-18. PMID:16407654. |
turner's syndrome (ts) is associated with increased insulin resistance and adiposity, which might be associated with type 2 diabetes in later life. |
2006-04-18 |
2023-08-12 |
Not clear |
| Burak Salgin, Rakesh Amin, Kevin Yuen, Rachel M Williams, Peter Murgatroyd, David B Dunge. Insulin resistance is an intrinsic defect independent of fat mass in women with Turner's syndrome. Hormone research. vol 65. issue 2. 2006-04-18. PMID:16407654. |
we aimed to determine whether the defect in insulin sensitivity is a primary intrinsic defect in ts or dependent on variation in body composition. |
2006-04-18 |
2023-08-12 |
Not clear |
| Maria C A de Armani, Alexandre Duarte Baldin, Sofia H V Lemos-Marini, Maria Tereza M Baptista, Andréa T Maciel-Guerra, Gil Guerra-Junio. [Evaluation of insulin resistance and lipid profile in turner syndrome]. Arquivos brasileiros de endocrinologia e metabologia. vol 49. issue 2. 2006-03-27. PMID:16184257. |
to evaluate the presence of insulin resistance (ir) and changes in lipid profile in turner syndrome (ts), and to check the influence of age, karyotype, systemic arterial hypertension (sah), height, weight, body mass index (bmi), and pubertal development. |
2006-03-27 |
2023-08-12 |
Not clear |
| In Kyoung Choi, Duk Hee Kim, Ho-Seong Ki. The abnormalities of carbohydrate metabolism in Turner syndrome: analysis of risk factors associated with impaired glucose tolerance. European journal of pediatrics. vol 164. issue 7. 2005-12-13. PMID:15856295. |
using a homeostatic model assessment (homa) and a quantitative insulin sensitivity check index (quicki), the insulin resistance in ts patients was investigated. |
2005-12-13 |
2023-08-12 |
Not clear |
| Jerzy Starzy. [Carbohydrate metabolism in patients with Turner syndrome. The effect of therapy with growth hormone, oxandrolone and a combination of both]. Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych. vol 11. issue 2. 2005-08-25. PMID:15996336. |
insulin resistance or the impairment of insulin capability to decrease blood glucose levels is seen in approximately 25% of girls with turner syndrome (ts). |
2005-08-25 |
2023-08-12 |
Not clear |
| Jerzy Starzy. [Carbohydrate metabolism in patients with Turner syndrome. The effect of therapy with growth hormone, oxandrolone and a combination of both]. Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych. vol 11. issue 2. 2005-08-25. PMID:15996336. |
growth hormone (hgh), especially when administered at pharmacological doses, may additionally negatively affect the carbohydrate metabolism in ts girls, changing the response of peripheral tissues to insulin. |
2005-08-25 |
2023-08-12 |
Not clear |
| Julia E Ostberg, E Louise Thomas, Gavin Hamilton, M Javad Hosseinzadeh Attar, Jimmy D Bell, Gerard S Conwa. Excess visceral and hepatic adipose tissue in Turner syndrome determined by magnetic resonance imaging: estrogen deficiency associated with hepatic adipose content. The Journal of clinical endocrinology and metabolism. vol 90. issue 5. 2005-06-09. PMID:15713713. |
obesity, predominantly centrally distributed, is common in women with turner syndrome (ts) and is thought to contribute to the increased risk of atherosclerosis; however, insulin concentrations are unexpectedly low. |
2005-06-09 |
2023-08-12 |
Not clear |
| Julia E Ostberg, M Javad Hosseinzadeh Attar, Vidya Mohamed-Ali, Gerard S Conwa. Adipokine dysregulation in turner syndrome: comparison of circulating interleukin-6 and leptin concentrations with measures of adiposity and C-reactive protein. The Journal of clinical endocrinology and metabolism. vol 90. issue 5. 2005-06-09. PMID:15728208. |
we conclude that women with ts have various physical and biochemical features suggestive of the metabolic/insulin resistance syndrome, but there is a discrepancy among crp, il-6, and leptin, with leptin and fasting insulin concentrations being lower than expected for the degree of obesity. |
2005-06-09 |
2023-08-12 |
human |
| Vladimir K Bakalov, Margaret M Cooley, Michael J Quon, Mei Lin Luo, Jack A Yanovski, Lawrence M Nelson, Gail Sullivan, Carolyn A Bond. Impaired insulin secretion in the Turner metabolic syndrome. The Journal of clinical endocrinology and metabolism. vol 89. issue 7. 2004-08-10. PMID:15240640. |
glucose-stimulated insulin secretion was lower in ts; e.g. |
2004-08-10 |
2023-08-12 |
Not clear |
| Vladimir K Bakalov, Margaret M Cooley, Michael J Quon, Mei Lin Luo, Jack A Yanovski, Lawrence M Nelson, Gail Sullivan, Carolyn A Bond. Impaired insulin secretion in the Turner metabolic syndrome. The Journal of clinical endocrinology and metabolism. vol 89. issue 7. 2004-08-10. PMID:15240640. |
we also compared responses to a standard iv glucose tolerance test in women with ts and in age- and body mass index-matched normal women and found that the insulin area under the curve was 50% lower in women with ts (p = 0.003). |
2004-08-10 |
2023-08-12 |
Not clear |
| Vladimir K Bakalov, Margaret M Cooley, Michael J Quon, Mei Lin Luo, Jack A Yanovski, Lawrence M Nelson, Gail Sullivan, Carolyn A Bond. Impaired insulin secretion in the Turner metabolic syndrome. The Journal of clinical endocrinology and metabolism. vol 89. issue 7. 2004-08-10. PMID:15240640. |
insulin sensitivity measured by the quantitative insulin sensitivity check index was higher in women with ts compared with both control groups. |
2004-08-10 |
2023-08-12 |
Not clear |
| Vladimir K Bakalov, Margaret M Cooley, Michael J Quon, Mei Lin Luo, Jack A Yanovski, Lawrence M Nelson, Gail Sullivan, Carolyn A Bond. Impaired insulin secretion in the Turner metabolic syndrome. The Journal of clinical endocrinology and metabolism. vol 89. issue 7. 2004-08-10. PMID:15240640. |
thus, igh is not secondary to obesity or hypogonadism in ts, but it is a distinct entity characterized by decreased insulin secretion, suggesting that haploinsufficiency for x-chromosome gene(s) impairs beta-cell function and predisposes to diabetes mellitus in ts. |
2004-08-10 |
2023-08-12 |
Not clear |
| Aneta Gawlik, Przemysława Jarosz-Chobo. [Diabetes mellitus type 1 among the patients with Turner syndrome or Turner syndrome among the patients with diabetes mellitus type 1?]. Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych. vol 8. issue 1. 2003-11-26. PMID:12818132. |
there are data from many centres interested in ts which confirm increased frequency of impaired glucose tolerance, insulin resistance and diabetes mellitus (dm) type 2 in ts. |
2003-11-26 |
2023-08-12 |
Not clear |
| Yvonne K Van Pareren, Sabine M P F De Muinck Keizer-Schrama, Theo Stijnen, Theo C J Sas, Stenvert L S Dro. Effect of discontinuation of long-term growth hormone treatment on carbohydrate metabolism and risk factors for cardiovascular disease in girls with Turner syndrome. The Journal of clinical endocrinology and metabolism. vol 87. issue 12. 2003-01-17. PMID:12466334. |
gh treatment increases insulin levels in girls with turner syndrome (ts), who are already predisposed to develop diabetes mellitus and other risk factors for developing cardiovascular disease. |
2003-01-17 |
2023-08-12 |
Not clear |