| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caren T D Antoniazzi, Nardeli Boufleur, Camila S Pase, Fábio T Kuhn, Verônica T Dias, Hecson J Segat, Karine Roversi, Katiane Roversi, Dalila M Benvegnú, Marilise E Bürge. Tactile stimulation and neonatal isolation affect behavior and oxidative status linked to cocaine administration in young rats. Behavioural processes. vol 103. 2014-11-17. PMID:24468216. |
ts reduced protein carbonyl (pc) in cortex and ni60 increased pc in both striatum and hippocampus of cocaine-treated rats. |
2014-11-17 |
2023-08-12 |
rat |
| Anna Effenberg, Alexander Klein, Robbin Gibb, Cathy Carroll, Wolfgang Baumgärtner, Claudia Grothe, Andreas Ratzk. Adult hemiparkinsonian rats do not benefit from tactile stimulation. Behavioural brain research. vol 261. 2014-10-06. PMID:24342749. |
in contrast ts applied to healthy rats elicited a transient short-term increase of fgf2 in the striatum and bdnf, grin1, and fgf2 in the hippocampus. |
2014-10-06 |
2023-08-12 |
rat |
| Kevin W McCairn, Masaki Isod. Pharmacological animal models of tic disorders. International review of neurobiology. vol 112. 2014-07-14. PMID:24295622. |
among a variety of pharmacological models, focal microinjection of gaba antagonists into the sensorimotor striatum has helped identify abnormal neural discharge in the global networks which underlie tourettism, including not only the cerebral cortex and basal ganglia but also the cerebellum, consistent with recent neuroimaging studies for ts subjects. |
2014-07-14 |
2023-08-12 |
human |
| Wen Zhang, Wenjing Yu, Daohan Wang, Li Wei, Minkyoung Lee, Sumei Wan. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-09. PMID:24812567. |
the purpose of this study was to explore the positive effects of jian-pi-zhi-dong decoction (jpzdd) on tourette syndrome (ts) by investigating the expression of gamma-aminobutyric acid (gaba) and its type a receptor (gabaar) in the striatum of a ts mice model. |
2014-05-09 |
2023-08-13 |
mouse |
| Wen Zhang, Wenjing Yu, Daohan Wang, Li Wei, Minkyoung Lee, Sumei Wan. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-09. PMID:24812567. |
we recorded the stereotypic behaviors of ts mice and measured the content of gaba in striatum by hplc and gabaar expression by immunohistochemistry and real-time pcr. |
2014-05-09 |
2023-08-13 |
mouse |
| Wen Zhang, Wenjing Yu, Daohan Wang, Li Wei, Minkyoung Lee, Sumei Wan. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-09. PMID:24812567. |
our results showed that jpzdd inhibited the abnormal behaviors of ts model mice and decreased gaba levels and gabaar protein and mrna expression in the striatum of ts model mice. |
2014-05-09 |
2023-08-13 |
mouse |
| Wen Zhang, Wenjing Yu, Daohan Wang, Li Wei, Minkyoung Lee, Sumei Wan. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-05-09. PMID:24812567. |
in brief, the mechanism by which jpzdd alleviates ts symptoms may be associated with gabaar expression downregulation in striatum which may regulate gaba metabolism. |
2014-05-09 |
2023-08-13 |
mouse |
| Dao-Han Wang, Wei Li, Xiao-Fang Liu, Jin-Ming Zhang, Su-Mei Wan. Chinese Medicine Formula "Jian-Pi-Zhi-Dong Decoction" Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-02-25. PMID:23431337. |
this study aims to investigate the expression of dopamine transporter (dat) in the striatum and stereotyped behavior of ts mice model by intervention of jpzdd. |
2013-02-25 |
2023-08-12 |
mouse |
| Dao-Han Wang, Wei Li, Xiao-Fang Liu, Jin-Ming Zhang, Su-Mei Wan. Chinese Medicine Formula "Jian-Pi-Zhi-Dong Decoction" Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-02-25. PMID:23431337. |
these findings not only demonstrated that jpzdd could effectively inhibit the abnormal behaviors of ts mice model, but also increase the level of dat in striatum. |
2013-02-25 |
2023-08-12 |
mouse |
| Arif Muhammad, Shakhawat Hossain, Sergio M Pellis, Bryan Kol. Tactile stimulation during development attenuates amphetamine sensitization and structurally reorganizes prefrontal cortex and striatum in a sex-dependent manner. Behavioral neuroscience. vol 125. issue 2. 2012-03-06. PMID:21463020. |
this study investigated the effect of postnatal tactile stimulation (ts) on juvenile behavior, adult amphetamine (amph) sensitization, and the interaction of ts and amph on prefrontal cortical (pfc) thickness and striatum size. |
2012-03-06 |
2023-08-12 |
rat |
| Arif Muhammad, Shakhawat Hossain, Sergio M Pellis, Bryan Kol. Tactile stimulation during development attenuates amphetamine sensitization and structurally reorganizes prefrontal cortex and striatum in a sex-dependent manner. Behavioral neuroscience. vol 125. issue 2. 2012-03-06. PMID:21463020. |
in summary, ts during development modulated the response to novel objects and altered social behaviors and attenuated amph-induced behavioral sensitization by preventing drug-induced structural alteration in the pfc and the striatum, brain regions implicated in drug abuse. |
2012-03-06 |
2023-08-12 |
rat |
| Arif Muhammad, Bryan Kol. Prenatal tactile stimulation attenuates drug-induced behavioral sensitization, modifies behavior, and alters brain architecture. Brain research. vol 1400. 2011-10-14. PMID:21652031. |
based on the findings of postnatal tactile stimulation (ts), a favorable experience in rats, the present study examined the influence of prenatal ts on juvenile behavior, adult amphetamine (amph) sensitization, and structural alteration in the prefrontal cortex (pfc) and the striatum. |
2011-10-14 |
2023-08-12 |
rat |
| Arif Muhammad, Bryan Kol. Prenatal tactile stimulation attenuates drug-induced behavioral sensitization, modifies behavior, and alters brain architecture. Brain research. vol 1400. 2011-10-14. PMID:21652031. |
furthermore, the drug-associated alteration in the prefrontal cortical thickness and striatum size observed in controls were prevented by ts experience. |
2011-10-14 |
2023-08-12 |
rat |
| Akihiko Hoshi, Teiji Yamamoto, Keiko Shimizu, Yoshihiro Sugiura, Yoshikazu Ugaw. Chemical preconditioning-induced reactive astrocytosis contributes to the reduction of post-ischemic edema through aquaporin-4 downregulation. Experimental neurology. vol 227. issue 1. 2011-02-04. PMID:20887723. |
the immunofluorescence analyses demonstrated that the aqp4 immunoreactivity in the cortex and striatum was significantly reduced in the ts group but not in the nts group. |
2011-02-04 |
2023-08-12 |
rat |
| Andrea Eugenio Cavanna, Clare Eddy, Hugh Edward Rickard. Cognitive functioning in Tourette syndrome. Discovery medicine. vol 8. issue 43. 2010-05-19. PMID:20040269. |
changes in functioning of the striatum in ts could lead to dysfunction in frontostriatal pathways involving cortical regions such as the dorsolateral prefrontal and anterior cingulate cortex. |
2010-05-19 |
2023-08-12 |
Not clear |
| Yuko Kataoka, Paul S A Kalanithi, Heidi Grantz, Michael L Schwartz, Clifford Saper, James F Leckman, Flora M Vaccarin. Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. The Journal of comparative neurology. vol 518. issue 3. 2010-03-08. PMID:19941350. |
in this study the density of different types of interneurons and medium spiny neurons (msns) in the striatum was assessed in the postmortem brains of 5 ts subjects as compared with normal controls (nc) by unbiased stereological analyses. |
2010-03-08 |
2023-08-12 |
human |
| Yuko Kataoka, Paul S A Kalanithi, Heidi Grantz, Michael L Schwartz, Clifford Saper, James F Leckman, Flora M Vaccarin. Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. The Journal of comparative neurology. vol 518. issue 3. 2010-03-08. PMID:19941350. |
cholinergic interneurons were decreased in ts patients in the associative and sensorimotor regions but not in the limbic regions of the striatum, such that the normal gradient in density of cholinergic cells (highest in associative regions, intermediate in sensorimotor and lowest in limbic regions) was abolished. |
2010-03-08 |
2023-08-12 |
human |
| Xiumei Liu, Yuwei Wang, Dong Li, Xiuli J. Transplantation of rat neural stem cells reduces stereotypic behaviors in rats after intrastriatal microinfusion of Tourette syndrome sera. Behavioural brain research. vol 186. issue 1. 2008-02-12. PMID:17850895. |
wistar rats were microinfused with ts sera into the striatum followed by the transplantation of nscs or vehicle at the infusion site. |
2008-02-12 |
2023-08-12 |
rat |
| Xiumei Liu, Yuwei Wang, Dong Li, Xiuli J. Transplantation of rat neural stem cells reduces stereotypic behaviors in rats after intrastriatal microinfusion of Tourette syndrome sera. Behavioural brain research. vol 186. issue 1. 2008-02-12. PMID:17850895. |
to sum it up, rat embryonic neural stem cell grafts survived and differentiated in the striatum of ts rat may help relieve stereotypic behaviors of the host. |
2008-02-12 |
2023-08-12 |
rat |
| Sven C Mueller, Georgina M Jackson, Ranu Dhalla, Sophia Datsopoulos, Chris P Holli. Enhanced cognitive control in young people with Tourette's syndrome. Current biology : CB. vol 16. issue 6. 2006-07-17. PMID:16546080. |
this idea is consistent with current views on the neurological basis of ts that posit a dysfunction of the neural circuits linking the frontal lobes and the striatum. |
2006-07-17 |
2023-08-12 |
Not clear |