| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiumei Liu, Xueming Wang, Aimin Li, Xiaoling Jia. Effect of mesenchymal stem cell transplantation on brain-derived neurotrophic factor expression in rats with Tourette syndrome. Experimental and therapeutic medicine. vol 11. issue 4. 2020-10-01. PMID:27073424. |
the aim of the present study was to investigate the effect of bone marrow mesenchymal stem cell (msc) transplantation on brain-derived neurotrophic factor (bdnf) expression in the striatum of tourette syndrome (ts) rats. |
2020-10-01 |
2023-08-13 |
rat |
| Haiyan Jiang, Hyoung F Ki. Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum. Frontiers in neuroanatomy. vol 12. 2020-10-01. PMID:29773980. |
the caudal region of the rodent striatum, called the tail of the striatum (ts), is a relatively small area but might have a distinct function from other striatal subregions. |
2020-10-01 |
2023-08-13 |
rat |
| Haiyan Jiang, Hyoung F Ki. Anatomical Inputs From the Sensory and Value Structures to the Tail of the Rat Striatum. Frontiers in neuroanatomy. vol 12. 2020-10-01. PMID:29773980. |
we identified inputs to the rat ts and compared those with inputs to the dorsomedial striatum (dms) in the same animals. |
2020-10-01 |
2023-08-13 |
rat |
| Wenjing Yu, Xiaowei Shi, Xia Cui, Yan Niu, Wen Zhang, Xue Bai, Qian Wang, Lijun Hu, Sumei Wan. Jian-Pi-Zhi-Dong-Decoction regulates the expression of glutamate transporters to attenuate glutamate excitotoxicity and exerts anti-tics effects in Tourette syndrome model rats. Neuropsychiatric disease and treatment. vol 14. 2020-09-29. PMID:30587990. |
this study explored whether jian-pi-zhi-dong-decoction (jpzdd) could regulate the metabolism of glutamate (glu) and its transporters in the striatum to exert anti-tics effects in tourette syndrome (ts) rats. |
2020-09-29 |
2023-08-13 |
rat |
| Pablo Andrade, Petra Heiden, Moritz Hoevels, Marc Schlamann, Juan C Baldermann, Daniel Huys, Veerle Visser-Vandewall. Modulation of Fibers to Motor Cortex during Thalamic DBS in Tourette Patients Correlates with Tic Reduction. Brain sciences. vol 10. issue 5. 2020-09-28. PMID:32429216. |
probabilistic tractography in tourette syndrome (ts) patients have shown an alteration in the connectivity of the primary motor cortex and supplementary motor area with the striatum and thalamus, suggesting an abnormal connectivity of the cortico-striatum-thalamocortical-pathways in ts. |
2020-09-28 |
2023-08-13 |
Not clear |
| Giuseppe Gangarossa, Laia Castell, Liliana Castro, Pauline Tarot, Frederic Veyrunes, Pierre Vincent, Federica Bertaso, Emmanuel Valjen. Contrasting patterns of ERK activation in the tail of the striatum in response to aversive and rewarding signals. Journal of neurochemistry. vol 151. issue 2. 2020-06-11. PMID:31245856. |
the caudal part of the striatum, also named the tail of the striatum (ts), defines a fourth striatal domain. |
2020-06-11 |
2023-08-13 |
mouse |
| Long Hongyan, Zhang Mengjiao, Wang Chunyan, Huang Yaru. Rhynchophylline Attenuates Neurotoxicity in Tourette Syndrome Rats. Neurotoxicity research. vol 36. issue 4. 2020-05-12. PMID:31115771. |
rh may significantly improve behavioral changes in rats with doi-induced ts and reduce the levels of inflammatory factors in serum and striatum. |
2020-05-12 |
2023-08-13 |
rat |
| Long Hongyan, Zhang Mengjiao, Wang Chunyan, Huang Yaru. Rhynchophylline Attenuates Neurotoxicity in Tourette Syndrome Rats. Neurotoxicity research. vol 36. issue 4. 2020-05-12. PMID:31115771. |
rh inhibited the activation of tlr/nlrp3/nf-κb signaling proteins in the striatum of ts rats. |
2020-05-12 |
2023-08-13 |
rat |
| Hongyan Long, Jie Ruan, Mengjiao Zhang, Chunyan Wang, Yaruo Huan. Rhynchophylline Attenuates Tourette Syndrome via BDNF/NF-κB Pathway In Vivo and In Vitro. Neurotoxicity research. vol 36. issue 4. 2020-05-12. PMID:31243645. |
dopamine (da) and dopamine receptor d 2 (d2) in striatum were also measured.data indicated that rh significantly decreased il-6, il-1β, and tnf-α in serum, striatum, and cell supernatant of ts model, with altered expression of p-nf-κbp65, p-iκbα, and bdnf in ts rats, and doi-induced bv2 cells, as evidenced by western blot analysis and immunohistochemistry analysis. |
2020-05-12 |
2023-08-13 |
rat |
| Mitsuko Watabe-Uchida, Naoshige Uchid. Multiple Dopamine Systems: Weal and Woe of Dopamine. Cold Spring Harbor symposia on quantitative biology. vol 83. 2020-01-09. PMID:30787046. |
in this review, we will summarize a series of our studies that have shown unique properties of dopamine neurons projecting to the posterior "tail" of the striatum (ts) in terms of anatomy, activity, and function. |
2020-01-09 |
2023-08-13 |
Not clear |
| Hongyan Long, Jie Ruan, Mengjiao Zhang, Chunyan Wang, Yaruo Huan. Gastrodin alleviates Tourette syndrome via Nrf-2/HO-1/HMGB1/NF-кB pathway. Journal of biochemical and molecular toxicology. vol 33. issue 10. 2019-12-13. PMID:31468582. |
ga may protect striatum of rats with ts by regulating nrf-2/ho-1/hmgb1/nf-кb pathway protein changes in striatum. |
2019-12-13 |
2023-08-13 |
rat |
| Long Hongyan, Zhang Mengjiao, Wang Chunyan, Huang Yaru. Rhynchophyllin attenuates neuroinflammation in Tourette syndrome rats via JAK2/STAT3 and NF-κB pathways. Environmental toxicology. vol 34. issue 10. 2019-11-22. PMID:31231976. |
rh significantly decreased il-6, il-1β, and tnf-α in serum and striatum of ts rats, with altered expression of p-jak2, p-stat3, p-nf-κbp65, and p-iκbα in ts rats, as evidenced by western blot analysis and immunohistochemistry, suggesting that the regulation of jak2/stat3 and nf-κb pathways might be involved in the mechanism of rh on ts. |
2019-11-22 |
2023-08-13 |
rat |
| Sachie K Ogawa, Mitsuko Watabe-Uchid. Organization of dopamine and serotonin system: Anatomical and functional mapping of monosynaptic inputs using rabies virus. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:28476484. |
it was found that the population of dopamine neurons that project to the tail of the striatum (ts) forms an anatomically distinct outlier, suggesting a unique function. |
2019-06-24 |
2023-08-13 |
Not clear |
| William Menegas, Korleki Akiti, Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli. Nature neuroscience. vol 21. issue 10. 2019-05-16. PMID:30177795. |
we found that the activity of dopamine axons in the posterior tail of the striatum (ts) scaled with the novelty and intensity of external stimuli, but did not encode reward value. |
2019-05-16 |
2023-08-13 |
Not clear |
| Ester Nespoli, Francesca Rizzo, Tobias Boeckers, Ulrike Schulze, Bastian Hengere. Altered dopaminergic regulation of the dorsal striatum is able to induce tic-like movements in juvenile rats. PloS one. vol 13. issue 4. 2018-07-31. PMID:29698507. |
the initial observation that dopaminergic antagonists alleviate tics led to the development of a dopaminergic theory of ts etiology which is supported by post mortem and in vivo studies indicating that non-physiological activation of the striatum could generate tics. |
2018-07-31 |
2023-08-13 |
rat |
| Long Hongyan, Wang Chunyan, Yang Yue'. LY294002, a PI3K inhibitor, attenuates Tourette syndrome in rats. Metabolic brain disease. vol 32. issue 5. 2018-07-23. PMID:28624893. |
ly294002 treatment significantly reduced il-6, il-1β and tnf-α in serum and striatum of ts rats, also, highly expressed p-pi3k, p-akt, p-nf-κbp65, p-iκbα in ts rats were restored respectively by ly294002 treatment as indicted in western blot analysis and immunohistochemistry analysis. |
2018-07-23 |
2023-08-13 |
rat |
| Maximiliano Rapanelli, Luciana Romina Frick, Meiyu Xu, Stephanie Mary Groman, Kantiya Jindachomthong, Nobuaki Tamamaki, Chiyoko Tanahira, Jane Rebecca Taylor, Christopher Pittenge. Targeted Interneuron Depletion in the Dorsal Striatum Produces Autism-like Behavioral Abnormalities in Male but Not Female Mice. Biological psychiatry. vol 82. issue 3. 2018-04-02. PMID:28347488. |
interneurons of the striatum, including the parvalbumin-expressing fast-spiking interneurons (fsis) and the large cholinergic interneurons (cins), are affected in patients with ts and in preclinical models of both asd and ts. |
2018-04-02 |
2023-08-13 |
mouse |
| David J Segar, Yosef G Chodakiewitz, Radmehr Torabi, G Rees Cosgrov. Deep brain stimulation for the obsessive-compulsive and Tourette-like symptoms of Kleefstra syndrome. Neurosurgical focus. vol 38. issue 6. 2016-03-31. PMID:26030700. |
a 24-year-old female patient with childhood hypotonia, developmental delay, and diagnoses of autism spectrum disorder, ocd, and ts refractory to medical management underwent the placement of bilateral ventral capsule/ventral striatum (vc/vs) dbs leads, with clinical improvement. |
2016-03-31 |
2023-08-13 |
Not clear |
| Xingju Nie, Eric D Hamlett, Ann-Charlotte Granholm, Edward S Hui, Joseph A Helpern, Jens H Jensen, Heather A Boger, Heather R Collins, Maria F Falangol. Evidence of altered age-related brain cytoarchitecture in mouse models of down syndrome: a diffusional kurtosis imaging study. Magnetic resonance imaging. vol 33. issue 4. 2016-01-04. PMID:25527393. |
at 5months of age, ts mice had lower radial kurtosis in the striatum (st), which persisted in the 8-month-old mice. |
2016-01-04 |
2023-08-13 |
mouse |
| Caren T D Antoniazzi, Nardeli Boufleur, Geisa Dolci, Karine Roversi, Fábio Kuhn, Camila S Pase, Verônica T Dias, Katiane Roversi, Raquel Barcelos, Dalila M Benvegnú, Marilise Escobar Bürge. Influence of neonatal tactile stimulation on amphetamine preference in young rats: parameters of addiction and oxidative stress. Pharmacology, biochemistry, and behavior. vol 124. 2015-05-19. PMID:25019651. |
the oxidative status indicated a protective influence of ts on brain tissues: lower lipid peroxidation (lp) and reduced protein carbonylation (pc) in the cortex, hippocampus and striatum. |
2015-05-19 |
2023-08-13 |
rat |