| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander von Hols. Tenascin C in stem cell niches: redundant, permissive or instructive? Cells, tissues, organs. vol 188. issue 1-2. 2008-09-19. PMID:18160825. |
here, i will concentrate on the multimodular extracellular matrix glycoprotein tenascin c (tnc) and discuss it as an exemplary molecule that is present in several stem cell niches. |
2008-09-19 |
2023-08-12 |
mouse |
| Hannelore Denys, Lara Derycke, An Hendrix, Wendy Westbroek, Alexander Gheldof, Kishan Narine, Patrick Pauwels, Christian Gespach, Marc Bracke, Olivier De Weve. Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion. Cancer letters. vol 266. issue 2. 2008-08-27. PMID:18423981. |
these effects are not mimicked or reversed by egf or bfgf, and are associated with the tgf-beta-mediated induction of myofibroblast differentiation and functional markers, such as alpha-sma, the haptotactic matrix molecule tnc, collagen type 1 maturation enzyme p4h, serine protease fap, and myofibroblast contractility. |
2008-08-27 |
2023-08-12 |
human |
| Grégory Chevillard, Anna Derjuga, Dominic Devost, Hans H Zingg, Volker Blan. Identification of interleukin-1beta regulated genes in uterine smooth muscle cells. Reproduction (Cambridge, England). vol 134. issue 6. 2008-04-07. PMID:18042638. |
we also found up-regulation of chemokines like c-x-c motif ligand 3 (cxcl3) and extracellular matrix remodeling signaling molecules like tenascin c (tnc). |
2008-04-07 |
2023-08-12 |
Not clear |
| Alexander von Holst, Ursula Egbers, Alain Prochiantz, Andreas Faissne. Neural stem/progenitor cells express 20 tenascin C isoforms that are differentially regulated by Pax6. The Journal of biological chemistry. vol 282. issue 12. 2007-05-02. PMID:17264084. |
tenascin c (tnc) is an alternatively spliced, multimodular extracellular matrix glycoprotein present in the ventricular zone of the developing brain. |
2007-05-02 |
2023-08-12 |
mouse |
| A El-Karef, T Yoshida, E C Gabazza, T Nishioka, H Inada, T Sakakura, K Imanaka-Yoshid. Deficiency of tenascin-C attenuates liver fibrosis in immune-mediated chronic hepatitis in mice. The Journal of pathology. vol 211. issue 1. 2007-03-28. PMID:17121418. |
tenascin-c (tnc), an extracellular matrix glycoprotein, is upregulated in chronic liver disease. |
2007-03-28 |
2023-08-12 |
mouse |
| Stéphane Fraichard, Anne-Laure Bouge, Isabelle Chauvel, Hervé Bouhi. Tenectin, a novel extracellular matrix protein expressed during Drosophila melanogaster embryonic development. Gene expression patterns : GEP. vol 6. issue 8. 2006-12-20. PMID:16510317. |
tnc is an extracellular matrix protein secreted in a polarized way in different organs of drosophila embryos. |
2006-12-20 |
2023-08-12 |
drosophila_melanogaster |
| Evandro Piva, Sandra B C Tarquínio, Flávio F Demarco, Adriana F Silva, Vera C de Araúj. Immunohistochemical expression of fibronectin and tenascin after direct pulp capping with calcium hydroxide. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. vol 102. issue 4. 2006-10-24. PMID:16997097. |
the aim of this study was to investigate the expression of 2 extracellullar matrix glycoproteins, fibronectin (fnc) and tenascin (tnc), following direct pulp capping with calcium hydroxide (ch). |
2006-10-24 |
2023-08-12 |
Not clear |
| Fabio Morellini, Melitta Schachne. Enhanced novelty-induced activity, reduced anxiety, delayed resynchronization to daylight reversal and weaker muscle strength in tenascin-C-deficient mice. The European journal of neuroscience. vol 23. issue 5. 2006-09-18. PMID:16553788. |
tenascin-c (tnc) is an extracellular matrix protein with multiple and important functions during development and in the adult. |
2006-09-18 |
2023-08-12 |
mouse |
| Antoine de Chevigny, Morgane Lemasson, Armen Saghatelyan, Miriam Sibbe, Melitta Schachner, Pierre-Marie Lled. Delayed onset of odor detection in neonatal mice lacking tenascin-C. Molecular and cellular neurosciences. vol 32. issue 1-2. 2006-09-07. PMID:16730455. |
we investigated the potential role of one of the constituents of the extracellular matrix, tenascin-c (tnc), in bulbar neurogenesis and olfactory performance using tnc-deficient mice. |
2006-09-07 |
2023-08-12 |
mouse |
| I Esposito, R Penzel, M Chaib-Harrireche, U Barcena, F Bergmann, S Riedl, H Kayed, N Giese, J Kleeff, H Friess, P Schirmache. Tenascin C and annexin II expression in the process of pancreatic carcinogenesis. The Journal of pathology. vol 208. issue 5. 2006-05-03. PMID:16450333. |
tenascin c (tnc) is a component of the provisional extracellular matrix (ecm) that characterizes solid tumours. |
2006-05-03 |
2023-08-12 |
Not clear |
| Orlando Guntinas-Lichius, Doychin N Angelov, Fabio Morellini, Mithra Lenzen, Emmanouil Skouras, Melitta Schachner, Andrey Irintche. Opposite impacts of tenascin-C and tenascin-R deficiency in mice on the functional outcome of facial nerve repair. The European journal of neuroscience. vol 22. issue 9. 2006-01-17. PMID:16262655. |
the glycoproteins tenascin-c (tnc) and tenascin-r (tnr) are extracellular matrix proteins involved in the development, plasticity and repair of the nervous system. |
2006-01-17 |
2023-08-12 |
mouse |
| Akira Matsuda, Tomomitsu Hirota, Mitsuteru Akahoshi, Makiko Shimizu, Mayumi Tamari, Akihiko Miyatake, Atsushi Takahashi, Kazuko Nakashima, Naomi Takahashi, Kazuhiko Obara, Noriko Yuyama, Satoru Doi, Yumiko Kamogawa, Tadao Enomoto, Koichi Ohshima, Tatsuhiko Tsunoda, Shoichiro Miyatake, Kimie Fujita, Moriaki Kusakabe, Kenji Izuhara, Yusuke Nakamura, Julian Hopkin, Taro Shirakaw. Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma. Human molecular genetics. vol 14. issue 19. 2005-12-23. PMID:16115819. |
the extracellular matrix glycoprotein tenascin-c (tnc) has been accepted as a valuable histopathological subepithelial marker for evaluating the severity of asthmatic disease and the therapeutic response to drugs. |
2005-12-23 |
2023-08-12 |
Not clear |
| Naoki Toma, Kyoko Imanaka-Yoshida, Taku Takeuchi, Satoshi Matsushima, Hiroo Iwata, Toshimichi Yoshida, Waro Tak. Tenascin-C-coated platinum coils for acceleration of organization of cavities and reduction of lumen size in a rat aneurysm model. Journal of neurosurgery. vol 103. issue 4. 2005-11-15. PMID:16266050. |
to reduce the incidence of recurrence by promoting clot organization, the authors designed a platinum coil coated with tenascin-c (tnc), an extracellular matrix glycoprotein, and then histologically examined tissue responses. |
2005-11-15 |
2023-08-12 |
rat |
| Jun-Hyeog Jang, Chong-Pyoung Chun. Tenascin-C promotes cell survival by activation of Akt in human chondrosarcoma cell. Cancer letters. vol 229. issue 1. 2005-11-14. PMID:16157221. |
tenascin-c (tnc) is an extracellular matrix protein that is highly expressed in tumor stroma. |
2005-11-14 |
2023-08-12 |
human |
| Andrey Irintchev, Astrid Rollenhagen, Edgardo Troncoso, Jozsef Z Kiss, Melitta Schachne. Structural and functional aberrations in the cerebral cortex of tenascin-C deficient mice. Cerebral cortex (New York, N.Y. : 1991). vol 15. issue 7. 2005-07-25. PMID:15537675. |
the extracellular matrix glycoprotein tenascin-c (tnc) has been implicated in neural development and plasticity but many of its functions in vivo remain obscure. |
2005-07-25 |
2023-08-12 |
mouse |
| T Nishio, S Kawaguchi, M Yamamoto, T Iseda, T Kawasaki, T Has. Tenascin-C regulates proliferation and migration of cultured astrocytes in a scratch wound assay. Neuroscience. vol 132. issue 1. 2005-07-20. PMID:15780469. |
tenascin-c (tnc), an extracellular matrix glycoprotein, is involved in tissue morphogenesis like embryogenesis, wound healing or tumorigenesis. |
2005-07-20 |
2023-08-12 |
Not clear |
| Olivier De Wever, Quang-Dé Nguyen, Leen Van Hoorde, Marc Bracke, Erik Bruyneel, Christian Gespach, Marc Maree. Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 9. 2004-11-02. PMID:15059978. |
we identified two convergent proinvasive agents secreted by myofibroblasts: namely scatter factor/hepatocyte growth factor (sf/hgf) and the tgf-beta-upregulated extracellular matrix glycoprotein tenascin-c (tnc), each of which is necessary though not sufficient for invasion. |
2004-11-02 |
2023-08-12 |
human |
| K Imanaka-Yoshida, M Hiroe, T Yoshid. Interaction between cell and extracellular matrix in heart disease: multiple roles of tenascin-C in tissue remodeling. Histology and histopathology. vol 19. issue 2. 2004-10-25. PMID:15024713. |
however, tnc is found to re-express after myocardial injury and may regulate cellular behavior during tissue remodeling by modulating the attachment of cardiomyocytes to connective tissue, by enhancing migration and differentiation of myofibroblasts, and by inducing matrix metallo-proteinases. |
2004-10-25 |
2023-08-12 |
Not clear |
| Kajiwara Kenji, Ueda Hironori, Yamamoto Hideya, Imazu Michinori, Hayashi Yasuhiko, Kohno Nobuok. Tenascin-C is associated with coronary plaque instability in patients with acute coronary syndromes. Circulation journal : official journal of the Japanese Circulation Society. vol 68. issue 3. 2004-09-28. PMID:14993772. |
tenascin-c (tnc) is an extracellular matrix glycoprotein that increases after inflammation and injury. |
2004-09-28 |
2023-08-12 |
human |
| Kajiwara Kenji, Ueda Hironori, Yamamoto Hideya, Imazu Michinori, Hayashi Yasuhiko, Kohno Nobuok. Tenascin-C is associated with coronary plaque instability in patients with acute coronary syndromes. Circulation journal : official journal of the Japanese Circulation Society. vol 68. issue 3. 2004-09-28. PMID:14993772. |
in cultured cells tnc has been reported to markedly induce the expression of matrix metalloproteinase-9, which stimulates collagen degradation in the fibrous cap of human atherosclerotic plaque. |
2004-09-28 |
2023-08-12 |
human |