| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joshua R Cook, Meredith A Hawkins, Utpal B Pajvan. Liver insulinization as a driver of triglyceride dysmetabolism. Nature metabolism. 2023-07-17. PMID:37460842. |
thus, even modestly elevated or context-inappropriate insulin levels, when sustained day and night within a heavily pro-lipogenic metabolic milieu, may translate into substantial cumulative tg biosynthesis in the insulin-resistant state. |
2023-07-17 |
2023-08-14 |
Not clear |
| Vehpi Yildirim, Kasper W Ter Horst, Pim W Gilijamse, Dewi van Harskamp, Henk Schierbeek, Hans Jansen, Alinda Wm Schimmel, Max Nieuwdorp, Albert K Groen, Mireille J Serlie, Natal Aw van Riel, Geesje M Dallinga-Thi. Bariatric surgery improves postprandial VLDL kinetics and restores insulin mediated regulation of hepatic VLDL production. JCI insight. 2023-07-11. PMID:37432744. |
here, we investigated the impact of roux-en-y gastric bypass (rygb) surgery on the postprandial vldl1 and vldl2 apob and tg kinetics and their relationship with insulin responsiveness indices. |
2023-07-11 |
2023-08-14 |
Not clear |
| Vehpi Yildirim, Kasper W Ter Horst, Pim W Gilijamse, Dewi van Harskamp, Henk Schierbeek, Hans Jansen, Alinda Wm Schimmel, Max Nieuwdorp, Albert K Groen, Mireille J Serlie, Natal Aw van Riel, Geesje M Dallinga-Thi. Bariatric surgery improves postprandial VLDL kinetics and restores insulin mediated regulation of hepatic VLDL production. JCI insight. 2023-07-11. PMID:37432744. |
furthermore, post-surgery vldl1 apob and tg production rates, but not vldl2, were positively correlated with insulin resistance. |
2023-07-11 |
2023-08-14 |
Not clear |
| Razieh Choghakhori, Amir Abbasnezhad, Mohammad Yazdi, Hassan Ahmadvan. Antidiabetic, hypolipidemic, and antioxidant activities of Pistacia atlantica: A systematic review and meta-analysis of preclinical studies. Phytotherapy research : PTR. 2023-07-10. PMID:37428094. |
this meta-analysis included 12 articles that examined the blood glucose (bg), insulin, homeostatic model assessment for insulin resistance (homa-ir), triglyceride (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), malondialdehyde (mda) and superoxide dismutase (sod). |
2023-07-10 |
2023-08-14 |
Not clear |
| Razieh Choghakhori, Amir Abbasnezhad, Mohammad Yazdi, Hassan Ahmadvan. Antidiabetic, hypolipidemic, and antioxidant activities of Pistacia atlantica: A systematic review and meta-analysis of preclinical studies. Phytotherapy research : PTR. 2023-07-10. PMID:37428094. |
findings indicated that pa supplementation significantly decreased bg, homa-ir, tc, tg, and mda, and increased insulin and sod in diabetic animals compared with control group (p < .05). |
2023-07-10 |
2023-08-14 |
Not clear |
| Yuka Hirakuni, Tomoyo Itonaga, Fumika Matsuda, Miwako Maeda, Kenji Ihar. Diabetic lipemia as a predisposing state to acute pancreatitis: a case report and literature review. Diabetology international. vol 14. issue 3. 2023-07-03. PMID:37397897. |
her serum triglyceride (tg) level was as high as 2490 mg/dl on admission and 11,072 mg/dl on day two during treatment with hydration and intravenous insulin infusion, whereas the critical situation was successfully stabilized by standard treatment for dka without the occurrence of pancreatitis. |
2023-07-03 |
2023-08-14 |
Not clear |
| Yuka Hirakuni, Tomoyo Itonaga, Fumika Matsuda, Miwako Maeda, Kenji Ihar. Diabetic lipemia as a predisposing state to acute pancreatitis: a case report and literature review. Diabetology international. vol 14. issue 3. 2023-07-03. PMID:37397897. |
the serum tg levels and dka successfully normalized in most of the cases with insulin infusion therapy with hydration, without other specific treatments (e.g., heparin therapy and plasmapheresis). |
2023-07-03 |
2023-08-14 |
Not clear |
| Rocío Fernández-Iglesias, Pablo Martinez-Camblor, Ana Fernández-Somoano, Cristina Rodríguez-Dehli, Rafael Venta-Obaya, Margaret R Karagas, Adonina Tardón, Isolina Riaño-Galá. Tracking between cardiovascular-related measures at 4 and 8 years of age in the INMA-Asturias cohort. European journal of pediatrics. 2023-06-20. PMID:37338691. |
in this study, the tracking of triglycerides (tg), high-density cholesterol (hdl-c), atherogenic coefficient (ac), waist circumference to height ratio (wc/height), mean arterial pressure (map), and homeostatic model assessment of insulin resistance (homa-ir) was examined in the inma-asturias cohort between 4 and 8 years of age. |
2023-06-20 |
2023-08-14 |
human |
| Hyeon Yang, Sun A Ock, Seunghoon Lee, Mi-Ryung Park, Seokho Kim, Jingu No, Keon Bong Oh, Hayeon Wi, Sun Keun Jung, Yong Jin Jo, Bo Ram Lee, Minguk Lee, Sung June Byu. Mortality, growth, and egg production do not differ between nontransgenic and transgenic female chickens with ubiquitous expression of the 3D8 single chain variable fragment gene. Poultry science. vol 102. issue 8. 2023-06-12. PMID:37307631. |
the levels of insulin growth factor-1 (igf-1), interferon-gamma (inf-γ), interleukin-4 (il-4), and il-8 were significantly lower in tg chickens (p < 0.05). |
2023-06-12 |
2023-08-14 |
chicken |
| Hsuan-Chih N Kuo, Zachary LaRussa, Flora Mengyang Xu, Kathryn West, Leslie Consitt, William Sean Davidson, Min Liu, Karen T Coschigano, Haifei Shi, Chunmin C L. Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice. Nutrients. vol 15. issue 11. 2023-06-11. PMID:37299447. |
in conclusion, continuous infusion of mouse apoa4 protein stimulated sympathetic activity in bat and the liver, elevated bat thermogenesis and hepatic fatty acid oxidation, and consequently attenuated levels of plasma and hepatic tg and plasma insulin without altering caloric intake, body weight gain and fat mass. |
2023-06-11 |
2023-08-14 |
mouse |
| Dušn Žitňn, František Sehnal, Akira Mizoguchi, Hironori Ishizaki, Hiromichi Nagasawa, Akinori Suzuk. Developmental Changes in the Bombyxin-and Insulin-like Immunoreactive Neurosecretory System in the Wax Moth, Galleria mellonella: (prothoracicotropins/corpora cardiaca/regulatory peptides/neurohaemal organs/molting control). Development, growth & differentiation. vol 32. issue 6. 2023-06-07. PMID:37281442. |
four medial neurosecretory cells (mnc) and 4 lateral neurosecretory cells (lnc) in each brain hemisphere, and one pair of cells in each thoracic ganglion (tg) of galleria larva react with antibodies against bombyxin and insulin. |
2023-06-07 |
2023-08-14 |
Not clear |
| Jiang Li, Shaofeng Xu, Ling Wang, Xiaoliang Wan. PHPB Attenuated Cognitive Impairment in Type 2 Diabetic KK-Ay Mice by Modulating SIRT1/Insulin Signaling Pathway and Inhibiting Generation of AGEs. Pharmaceuticals (Basel, Switzerland). vol 16. issue 2. 2023-06-01. PMID:37259448. |
furthermore, we found that phpb treatment significantly reduced ages generation via up-regulation of glyoxalase-1 (glo1) protein and enhancement of methylglyoxal (mg) trapping, while there was no obvious difference in levels of glucose in plasma or brain, contents of total cholesterol (tc), triglycerides (tg), and plasma insulin. |
2023-06-01 |
2023-08-14 |
mouse |
| Myong-Won Seo, Wonhee Cho, Joon Young Ki. The single point insulin sensitivity estimator (SPISE) index as a predictor of metabolic syndrome in Korean adults. Obesity research & clinical practice. 2023-05-28. PMID:37246046. |
recently, the single-point insulin sensitivity estimator (spise) has been developed as a simple surrogate of insulin resistance based on bmi, triglycerides (tg), and hdl-c. |
2023-05-28 |
2023-08-14 |
Not clear |
| Kimitaka Nakazaki, Nobuhiko Nagano, Daichi Katayama, Shoichi Shimizu, Kengo Matsuda, Wataru Tokunaga, Ryoji Aoki, Kazumasa Fuwa, Ichiro Moriok. Body Fat-Reducing Effects of Whey Protein Diet in Male Mice. Nutrients. vol 15. issue 10. 2023-05-27. PMID:37242144. |
at 12 weeks of age, body weight, fat mass, fasting blood glucose (fbg), insulin (iri), homeostatic model assessment of insulin resistance (homa-ir), cholesterol (cho), triglyceride (tg), the expression levels of lipid metabolism-related genes in liver tissues and metabolomic data of fat tissues were measured and compared between the groups. |
2023-05-27 |
2023-08-14 |
mouse |
| Jing Liu, Xu Wang, Qiyao Li, Chengyu Piao, Zuowang Fan, Yao Zhang, Saisai Yang, Xiuhong W. Fecal metabolomics combined with 16S rRNA gene sequencing to analyze the effect of Jiaotai pill intervention in type 2 diabetes mellitus rats. Frontiers in nutrition. vol 10. 2023-05-25. PMID:37229468. |
the results showed that jtp decreased blood glucose (fbg, hba1c) and blood lipid (tc, tg, and ldl) levels and alleviated insulin resistance (fins, il-10) in t2dm rats. |
2023-05-25 |
2023-08-14 |
rat |
| Delia-Maria Nicoară, Andrei-Ioan Munteanu, Alexandra-Cristina Scutca, Niculina Mang, Iulius Juganaru, Giorgiana-Flavia Brad, Otilia Mărginea. Assessing the Relationship between Systemic Immune-Inflammation Index and Metabolic Syndrome in Children with Obesity. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37176120. |
we designed this study to investigate the diagnostic utility of inflammatory indices (nlr, neutrophil-to-lymphocyte ratio; plr, platelet-to-lymphocyte ratio; sii, systemic immune-inflammation index; siri, systemic inflammation response index) in obese children with metabolic syndrome (mets) and their relationship with cardiometabolic risk biomarkers, such as the homeostasis model assessment of insulin resistance (homa-ir), triglyceride-to-high-density lipoprotein cholesterol (tg:hdl-c), and non-high-density lipoprotein cholesterol (non-hdl-c). |
2023-05-14 |
2023-08-14 |
Not clear |
| Tao Wang, Chao Yu, Guo-Tao Yu, Wei Zhou, Ling-Juan Zhu, Xiao Huang, Hui-Hui Bao, Xiao-Shu Chen. [Predictive Effects of Different Insulin Resistance Indexes on Diabetes Risk in Hypertensive Population]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 45. issue 2. 2023-05-08. PMID:37157066. |
objective to explore the roles of different insulin resistance indexes[triglyceride-glucose (tyg),triglyceride (tg)/high-density lipoprotein cholesterol (hdl-c),and metabolic score for insulin resistance (mets-ir)]and combinations of two indexes in predicting diabetes risk in hypertensive population. |
2023-05-08 |
2023-08-14 |
Not clear |
| Jun S Lai, Marjorelee T Colega, Keith M Godfrey, Kok Hian Tan, Fabian Yap, Yap Seng Chong, Yung Seng Lee, Johan G Eriksson, Shiao-Yng Chan, Mary F F Chon. Changes in Diet Quality from Pregnancy to 6 Years Postpregnancy and Associations with Cardiometabolic Risk Markers. Nutrients. vol 15. issue 8. 2023-04-28. PMID:37111088. |
fasting triglyceride (tg), total-, high- and low-density-lipoprotein cholesterol (tc, hdl- and ldl-c), glucose and insulin were measured 8 years postpregnancy; homeostatic model assessment for insulin resistance (homa-ir) and tg: hdl-c ratio were derived. |
2023-04-28 |
2023-08-14 |
Not clear |
| Xiaomei Zhang, Huifeng Zhang, Weidong Qiang, Yongxin Guo, Di Wu, Xin Su. Oral administration of human FGF21 expressed by mycelium of Cordyceps militaris improves blood glucose and lipid in type II diabetes mellitus. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 10. 2023-04-28. PMID:37114272. |
in animal experiments, oral rhfgf21 obviously reduced the levels of glucose, insulin, tg, t-cho, nefa, and ldl-c in the blood, the contents of alt, ast, tnf-α, mcp-1, f4/80, cd68 and cd11b in the fatty liver, and the apoptosis of pancreatic cells. |
2023-04-28 |
2023-08-14 |
human |
| Xinlei Yao, Lei Liu, Wenjun Shao, Miao Bai, Xiaohan Ding, Geng Wang, Shuyue Wang, Lihua Zheng, Ying Sun, Guannan Wang, Yanxin Huang, Chunlei Yu, Zhenbo Song, Yongli Bao, Shaonian Yang, Luguo Su. Tectorigenin targets PKACα to promote GLUT4 expression in skeletal muscle and improve insulin resistance International journal of biological sciences. vol 19. issue 5. 2023-04-14. PMID:37056927. |
here, we demonstrate that the natural compound tectorigenin (tg) enhances glut4 expression, glucose uptake and insulin responsiveness via activating amp-activated protein kinase (ampk)/myocyte enhancer factor 2 (mef2) signaling in both normal and ir skeletal muscle cells and tissues. |
2023-04-14 |
2023-08-14 |
mouse |