Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Selcen Çaki. Effect of Boric Acid on Metabolic Peptides and Some Biochemical Parameters in Experimental Diabetic Rats. Biological trace element research. 2023-10-23. PMID:37872360. |
serum asprosin, nesfatin-1, preptin, insulin, total cholesterol (tc), triglyceride (tg), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), aspartate transaminase (ast), alanine transaminase (alt), and glucose analyses were performed. |
2023-10-23 |
2023-11-08 |
rat |
Guliqiekeran Aisike, Maierheba Kuerbanjiang, Dina Muheyati, Kaibinuer Zaibibuli, Mei-Xia Lv, Jia Ha. Correlation analysis of obesity phenotypes with leptin and adiponectin. Scientific reports. vol 13. issue 1. 2023-10-20. PMID:37853077. |
compared to both the hc and mho groups, the muo group showed significantly higher bmi, waist circumference (wc), waist-hip ratio (whr), triglyceride (tg), total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c), fasting plasma glucose (fpg), homeostasis model assessment of insulin resistance (homa-ir) and blood pressure (p < 0.05). |
2023-10-20 |
2023-11-08 |
human |
Yukako Yamamoto, Takeshi Togawa, Osamu Sekine, Yuki Ozamoto, Junko Fuse, Choka Azuma, Jun Ito-Kobayashi, Yasumitsu Oe, Akeo Hagiwara, Masaki Kobayashi, Tadahiro Kitamura, Masanori Iwanishi, Akira Shimatsu, Atsunori Kashiwag. The oral disposition index calculated from a meal tolerance test is a crucial indicator for evaluating differential normalization of postprandial glucose and triglyceride excursions in morbidly obese patients after laparoscopic sleeve gastrectomy. Endocrine journal. 2023-10-19. PMID:37853621. |
(iv) the baseline, 2h-tg, and an increase in 2h-tg values above baseline were correlated with the insulin resistance index, di, or hba1c; these tg values were normalized post-lsg. |
2023-10-19 |
2023-11-08 |
Not clear |
Yi-Xin Xiang, Ya-Lan Huang, Min Zhou, Jun-Ju Zou, Xiu Liu, Zi-Yu Liu, Fan Xiao, Rong Yu, Qin Xian. [Zuogui Jiangtang Qinggan Formula improves glucolipid metabolism in type 2 diabetes mellitus complicated with non-alcoholic fatty liver disease by regulating FoxO1/MTP/APOB signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 16. 2023-10-06. PMID:37802870. |
the results showed that high-dose zgjtqg could signi-ficantly reduce the fbg and fins levels(p<0.05, p<0.01), improve glucose tolerance and insulin resistance(p<0.05, p<0.01), alleviate the liver damage caused by hfd which was reflected in improving liver steatosis, and reduce the serum levels of tc, tg, ldl, vldl, alt, and ast(p<0.05, p<0.01) in t2dm mice combined with nafld. |
2023-10-06 |
2023-10-15 |
mouse |
Jiwon Kim, Woojeong Noh, Ahrim Kim, Yoomin Choi, Young-Sik Ki. The Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762302. |
we used either a random effect model or a fixed model in a meta-analysis of fasting blood glucose (fbg), 2 h plasma glucose during a 75 g oral glucose tolerance test (ogtt) (2-hpg), homeostatic model assessment for insulin resistance (homa-ir), glycosylated hemoglobin (hba1c)/total cholesterol (tc), triglyceride (tg), high density lipoprotein (hdl-c), low density lipoprotein (ldl-c), body mass index (bmi). |
2023-09-28 |
2023-10-07 |
human |
Stephanie E Areloegbe, Kehinde S Olaniy. Acetate mitigates cardiac mitochondrial dysfunction in experimental model of polycystic ovarian syndrome by modulating GPCR41/43 and PROKR1. Biochemical and biophysical research communications. vol 681. 2023-09-27. PMID:37757668. |
in addition, these rats also manifested insulin resistance, hyperinsulinemia, and increased plasma triglyceride (tg), tg/hdlc and decreased hdlc, as well as elevated level of cardiac tg, glycogen, glycogen synthase, and plasma/cardiac nf-kb, tnf-α, and sdf-1. |
2023-09-27 |
2023-10-07 |
rat |
Zhonghua Luo, Jing Xu, Qingqing Gao, Zhifang Wang, Mingxiao Hou, Yunen Li. Study on the effect of licochalcone A on intestinal flora in type 2 diabetes mellitus mice based on 16S rRNA technology. Food & function. 2023-09-13. PMID:37702574. |
the results indicated that lica could reduce serum tc, tg, and ldl-c levels, increase hdl-c levels, reduce blood glucose, and improve insulin resistance and glucose tolerance. |
2023-09-13 |
2023-10-07 |
mouse |
Jennifer Leohr, Maria C Kjellsso. Evaluation of postprandial total triglycerides within the TIGG model for characterizing postprandial response of glucose, insulin, and GLP-1. CPT: pharmacometrics & systems pharmacology. 2023-09-05. PMID:37667531. |
the tigg model is the first model to integrate glucose and insulin regulation, incretin effect, and triglyceride (tg) response in the lipoprotein subclasses of chylomicrons and vldl-v6. |
2023-09-05 |
2023-09-07 |
Not clear |
Min Shen, Liying Jiang, Hechun Liu, Hao Dai, Hemin Jiang, Yu Qian, Zhixiao Wang, Shuai Zheng, Heng Chen, Tao Yang, Qi Fu, Kuanfeng X. Interaction between the GCKR rs1260326 variant and serum HDL cholesterol contributes to HOMA-β and ISI Journal of human genetics. 2023-08-30. PMID:37648893. |
we found that serum high-density lipoprotein (hdl) cholesterol and triglyceride (tg) levels were independently correlated with indexes of islet function (homa-β and igi [insulinogenic index]) and insulin resistance (homo-ir and isi |
2023-08-30 |
2023-09-07 |
Not clear |
Yi-Wei Lee, Ting-Teng Yang, Yan-Yu Lin, Yu-Shan Hsie. Elevated Free Thyroxine Levels Might Alter the Effect of the Lipid Profile on Insulin Resistance in Type 2 Diabetes Mellitus. Diagnostics (Basel, Switzerland). vol 13. issue 16. 2023-08-26. PMID:37627914. |
the serum test results demonstrated that free thyroxine (ft4) increased the insulin resistance index (homa-ir) by positively correlating with triglyceride (tg) levels ( |
2023-08-26 |
2023-09-07 |
human |
Deepankar Ratha, Biswakanth Kar, Gurudutta Pattnaik, Pallishree Bhukt. Synergistic Effect of Naringin and Glimepiride in Streptozotocin-induced Diabetic Rats. Current diabetes reviews. 2023-08-18. PMID:37592777. |
conclusion a synergistic effect of naringin and glimepiride was observed during the estimation of various biochemical parameters like body weight, fasting blood sugar, creatinine, urine level, tg, total cholesterol, sgot, sgpt, alp, insulin, hba1c, antioxidant parameters like sod, gsh, and catalase in stz-induced diabetic rats. |
2023-08-18 |
2023-09-07 |
rat |
Annemarie Lundsgaard, Kirstine Nyvold Bojsen-Møller, Bente Kien. Dietary regulation of hepatic triacylglycerol content - the role of eucaloric carbohydrate restriction with fat or protein replacement. Advances in nutrition (Bethesda, Md.). 2023-08-17. PMID:37591342. |
the summarized findings from human intervention studies investigating the effect of reduced dietary carbohydrate and increased fat intake (and in studies also increased protein) while maintaining energy intake at eucaloric requirements reveal a beneficial effect of carbohydrate reduction on hepatic tg content in obese individuals with steatosis and indices of insulin resistance. |
2023-08-17 |
2023-09-07 |
human |
Jinyun Jing, Juan Li, Ni Yan, Nan Li, Xiaowei Liu, Xiaoxia Li, Jiaxing Zhang, Qingan Wang, Chan Yang, Jiangwei Qiu, Xiuying Liu, Faxuan Wang, Yi Zhao, Yuhong Zhan. Increased TG Levels and HOMA-IR Score Are Associated With a High Risk of Prediabetes: A Prospective Study. Asia-Pacific journal of public health. 2023-08-08. PMID:37551032. |
the study found that maintained or elevated homeostatic model assessment for insulin resistance (homo-ir) score and elevated triglyceride (tg) levels from baseline to follow-up were associated with an increased risk of prediabetes. |
2023-08-08 |
2023-08-14 |
human |
Seyed Reza Mirjalili, Sepideh Soltani, Zahra Heidari Meybodi, Pedro Marques-Vidal, Alexander Kraemer, Mohammadtaghi Sarebanhassanabad. An innovative model for predicting coronary heart disease using triglyceride-glucose index: a machine learning-based cohort study. Cardiovascular diabetology. vol 22. issue 1. 2023-08-04. PMID:37542255. |
although these models consider diabetes as an important chd risk factor, they do not consider insulin resistance or triglyceride (tg). |
2023-08-04 |
2023-08-14 |
Not clear |
Seyed Reza Mirjalili, Sepideh Soltani, Zahra Heidari Meybodi, Pedro Marques-Vidal, Alexander Kraemer, Mohammadtaghi Sarebanhassanabad. An innovative model for predicting coronary heart disease using triglyceride-glucose index: a machine learning-based cohort study. Cardiovascular diabetology. vol 22. issue 1. 2023-08-04. PMID:37542255. |
we decided to modify standard chd predictive models through machine learning to determine whether the triglyceride-glucose index (tyg-index, a logarithmized combination of fasting blood sugar (fbs) and tg that demonstrates insulin resistance) functions better than diabetes as a chd predictor. |
2023-08-04 |
2023-08-14 |
Not clear |
Minchuan Zhou, Jingqing Huang, Jingwen Zhou, Cuiting Zhi, Yan Bai, Qishi Che, Hua Cao, Jiao Guo, Zhengquan S. Anti-Obesity Effect and Mechanism of Chitooligosaccharides Were Revealed Based on Lipidomics in Diet-Induced Obese Mice. Molecules (Basel, Switzerland). vol 28. issue 14. 2023-07-29. PMID:37513467. |
the results show that cosm administration reduced body weight; slowed weight gain; reduced serum glu, insulin, nefa, tc, tg, and ldl-c levels; increased serum hsl and hdl-c levels; improved inflammation; and reduced lipid droplet size in adipose tissue. |
2023-07-29 |
2023-08-14 |
mouse |
Joshua R Cook, Meredith A Hawkins, Utpal B Pajvan. Liver insulinization as a driver of triglyceride dysmetabolism. Nature metabolism. 2023-07-17. PMID:37460842. |
we focus particularly on the relative preservation of insulin's stimulation of triglyceride (tg) biosynthesis despite its waning ability to curb hepatic glucose production (hgp). |
2023-07-17 |
2023-08-14 |
Not clear |
Joshua R Cook, Meredith A Hawkins, Utpal B Pajvan. Liver insulinization as a driver of triglyceride dysmetabolism. Nature metabolism. 2023-07-17. PMID:37460842. |
to explain this apparent 'selective insulin resistance', we propose that hepatocellular processes that lead to tg accumulation require less insulin signal transduction, or 'insulinization,' than do those that regulate hgp. |
2023-07-17 |
2023-08-14 |
Not clear |
Joshua R Cook, Meredith A Hawkins, Utpal B Pajvan. Liver insulinization as a driver of triglyceride dysmetabolism. Nature metabolism. 2023-07-17. PMID:37460842. |
thus, even modestly elevated or context-inappropriate insulin levels, when sustained day and night within a heavily pro-lipogenic metabolic milieu, may translate into substantial cumulative tg biosynthesis in the insulin-resistant state. |
2023-07-17 |
2023-08-14 |
Not clear |
Vehpi Yildirim, Kasper W Ter Horst, Pim W Gilijamse, Dewi van Harskamp, Henk Schierbeek, Hans Jansen, Alinda Wm Schimmel, Max Nieuwdorp, Albert K Groen, Mireille J Serlie, Natal Aw van Riel, Geesje M Dallinga-Thi. Bariatric surgery improves postprandial VLDL kinetics and restores insulin mediated regulation of hepatic VLDL production. JCI insight. 2023-07-11. PMID:37432744. |
here, we investigated the impact of roux-en-y gastric bypass (rygb) surgery on the postprandial vldl1 and vldl2 apob and tg kinetics and their relationship with insulin responsiveness indices. |
2023-07-11 |
2023-08-14 |
Not clear |