| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shao-Yang Zhao, Huan-Huan Zhao, Ting-Ting Hao, Wei-Wei Li, Hao- Gu. Effect of Bushen Huoxue Prescription on Cognitive Dysfunction of KK-Ay Type 2 Diabetic Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-03-30. PMID:33777159. |
triglycerides (tg), cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), fasting serum insulin (fins), and morris water maze were tested after 12 weeks of administration. |
2021-03-30 |
2023-08-13 |
mouse |
| Shao-Yang Zhao, Huan-Huan Zhao, Ting-Ting Hao, Wei-Wei Li, Hao- Gu. Effect of Bushen Huoxue Prescription on Cognitive Dysfunction of KK-Ay Type 2 Diabetic Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-03-30. PMID:33777159. |
our results showed that bshx treatment significantly ameliorated the t2dm related insults, including the increased bodyweight, blood glucose, tg, insulin levels, ages, the reduced hdl-c, the impaired spatial memory, and the neurological impairment. |
2021-03-30 |
2023-08-13 |
mouse |
| Kengo Moriyam. The Association between the Triglyceride to High-density Lipoprotein Cholesterol Ratio and Low-density Lipoprotein Subclasses. Internal medicine (Tokyo, Japan). vol 59. issue 21. 2021-03-22. PMID:32669498. |
objective the triglyceride (tg)/high-density lipoprotein cholesterol (hdl-c) ratio is related to insulin resistance (ir). |
2021-03-22 |
2023-08-13 |
human |
| LeBris S Quinn, Barbara G Anderson, Jennifer D Conner, Emidio E Pistilli, Tami Wolden-Hanso. Overexpression of interleukin-15 in mice promotes resistance to diet-induced obesity, increased insulin sensitivity, and markers of oxidative skeletal muscle metabolism. International journal of interferon, cytokine and mediator research. vol 3. 2021-03-19. PMID:28943758. |
in the present study, an il-15 gain-of-function model, transgenic mice with skeletal muscle-specific oversecretion of il-15 (il-15 tg mice), was utilized to test the hypotheses that il-15 promotes insulin sensitivity and resistance to diet-induced obesity (dio) by increasing circulating adiponectin levels, and that il-15 regulates skeletal muscle metabolism without inducing overt muscle hypertrophy. |
2021-03-19 |
2023-08-13 |
mouse |
| LeBris S Quinn, Barbara G Anderson, Jennifer D Conner, Emidio E Pistilli, Tami Wolden-Hanso. Overexpression of interleukin-15 in mice promotes resistance to diet-induced obesity, increased insulin sensitivity, and markers of oxidative skeletal muscle metabolism. International journal of interferon, cytokine and mediator research. vol 3. 2021-03-19. PMID:28943758. |
compared to closely related control mice, il-15 tg mice exhibited lower total body fat following high-fat feeding, lower intra-abdominal fat following both low- and high-fat feeding, and greater insulin sensitivity. |
2021-03-19 |
2023-08-13 |
mouse |
| Emad H Kutbi, Mohammad Hassan Sohouli, Somaye Fatahi, Abolfazl Lari, Farzad Shidfar, Maha Mari Aljhdali, Faisal Musaad Alhoshan, Saad Saif Elahi, Hashem Ameen Almusa, Ahmed Abu-Zai. The beneficial effects of cinnamon among patients with metabolic diseases: A systematic review and dose-response meta-analysis of randomized-controlled trials. Critical reviews in food science and nutrition. 2021-03-19. PMID:33739219. |
pooling of results showed a significant reducing effect of cinnamon on total cholesterol (tc) (weighted mean difference (wmd) = -11.67 mg/dl; p = 0.010), triglyceride (tg) (wmd = -16.27 mg/dl; p < 0.001), low density lipoprotein-cholesterol (ldl-c) (wmd = -6.36 mg/dl; p < 0.001), serum glucose (wmd = -11.39 mg/dl; p < 0.001), serum insulin (wmd = -1.27 μiu/ml; p = 0.028), and waist circumstance (wc) (wmd = -1.68 cm; p = 0.016). |
2021-03-19 |
2023-08-13 |
Not clear |
| Jing Dong, Qiongxin Liang, Yun Niu, Shengjun Jiang, Li Zhou, Jinmei Wang, Changyang Ma, Wenyi Kan. Effects of Nigella sativa seed polysaccharides on type 2 diabetic mice and gut microbiota. International journal of biological macromolecules. vol 159. 2021-03-18. PMID:32437806. |
results showed that the high-dose nssp could significantly lower the levels of fbg, glycosylated serum protein (gsp), triglycerides (tg), total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c), malondialdehyde (mda), tnf-α, il-6 and il-1β, and significantly increased insulin (ins), high-density lipoprotein cholesterol (hdlc), total antioxidant capacity (t-aoc), superoxide dismutase (sod), catalase (cat) and the expression levels of p-akt and glut4 in mice. |
2021-03-18 |
2023-08-13 |
mouse |
| Antony Stalin, Subramani Kandhasamy, Balakrishnan Senthamarai Kannan, Rama Shanker Verma, Savarimuthu Ignacimuthu, Yrjälä Kim, Qingsong Shao, Yuan Chen, Perumal Palan. Synthesis of a 1,2,3-bistriazole derivative of embelin and evaluation of its effect on high-fat diet fed-streptozotocin-induced type 2 diabetes in rats and molecular docking studies. Bioorganic chemistry. vol 96. 2021-03-11. PMID:31978685. |
supplementation significantly (p ≤ 0.01) normalized the changed biochemical parameters like fasting blood glucose (fbg), body weights, plasma insulin level, total cholesterol (tc), triglycerides (tg) and marker enzymes of carbohydrate metabolism. |
2021-03-11 |
2023-08-13 |
rat |
| Neda S Akhavan, Shirin Pourafshar, Sarah A Johnson, Elizabeth M Foley, Kelli S George, Joseph Munoz, Shalom Siebert, Elizabeth A Clark, Raedeh Basiri, Robert C Hickner, Negin Navaei, Cathy W Levenson, Lynn B Panton, Bruce P Daggy, Bahram H Arjmand. The Relationship between Protein Intake and Source on Factors Associated with Glycemic Control in Individuals with Prediabetes and Type 2 Diabetes. Nutrients. vol 12. issue 7. 2021-03-11. PMID:32650580. |
higher animal protein intake was associated with greater insulin secretion and lower triglycerides (tg). |
2021-03-11 |
2023-08-13 |
human |
| Li-Li Huang, Xiao-Qiang Huang, Xiao-Qin Zhang, Jian Liu, Yi-Ping Zhang, Hai-Yu Zhao, Ming-Qing Huan. [Effect of fucoxanthin on insulin resistance in obese mice induced by high fat diet]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 1. 2021-03-02. PMID:33645067. |
fasting blood glucose(fbg), fasting insulin(fins), total cholesterol(tc), triglyceride(tg), low-density lipoprotein(ldl-c) and high-density lipoprotein(hdl-c) were measured, and insulin resistance index(homa-ir) was calcula-ted. |
2021-03-02 |
2023-08-13 |
mouse |
| Bingran Wang, Jiayan Zhang, Yuhong Lu, Long Peng, Wenling Yuan, Yuqing Zhao, Liping Zhan. ChaiQi Decoction Alleviates Vascular Endothelial Injury by Downregulating the Inflammatory Response in ApoE-Model Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-02-26. PMID:33628325. |
to evaluate the metabolic levels of mice, we determined the fasting blood glucose (fbg), fasting serum insulin (fins), insulin resistance index (iri), triglyceride (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), and low-density lipoprotein cholesterol (ldl-c) levels. |
2021-02-26 |
2023-08-13 |
mouse |
| Yu Yang, Shengqin Chen, Yang Liu, Yingbei Huang, Kit-Leong Cheong, Bo Teng, Wenhua Li. Long-term treatment of polysaccharides-based hydrogel microparticles as oral insulin delivery in streptozotocin-induced type 2 diabetic mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-24. PMID:33232923. |
the concentration of plasma tg, tc, ldl-c, ffa, bun, cre significantly decreased and the levels of hdl-c increased showed that insulin polysaccharides-based hydrogel microparticles were effective in regulating lipid metabolism and prevent diabetic nephropathy complication in diabetic mice. |
2021-02-24 |
2023-08-13 |
mouse |
| Ming-Xing Wang, Qian Yin, Xin X. A Rat Model of Polycystic Ovary Syndrome with Insulin Resistance Induced by Letrozole Combined with High Fat Diet. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-02-18. PMID:32448863. |
on day 22, 25, 28 and 31, the weight, and the short and long diameters of the rat ovaries were measured, and blood samples were collected for the measurement of fasting plasma glucose (fpg), fasting insulin (fins), triglyceride (tg), luteinizing hormone (lh), follicle stimulating hormone (fsh), and testosterone (t). |
2021-02-18 |
2023-08-13 |
rat |
| Amalie London, Anne-Marie Lundsgaard, Bente Kiens, Kirstine Nyvold Bojsen-Mølle. The Role of Hepatic Fat Accumulation in Glucose and Insulin Homeostasis-Dysregulation by the Liver. Journal of clinical medicine. vol 10. issue 3. 2021-02-18. PMID:33498493. |
in this narrative review, we summarize the effects of hepatic tg accumulation on hepatic glucose and insulin metabolism and the underlying molecular regulation in order to highlight the importance of hepatic tg accumulation for whole-body glucose metabolism. |
2021-02-18 |
2023-08-13 |
Not clear |
| Jinfeng Fu, Yuting Wang, Simin Tan, Juan Wan. Effects of Banana Resistant Starch on the Biochemical Indexes and Intestinal Flora of Obese Rats Induced by a High-Fat Diet and Their Correlation Analysis. Frontiers in bioengineering and biotechnology. vol 9. 2021-02-16. PMID:33585429. |
after 6 weeks of intervention, the glucolipid metabolism index [blood glucose (glu), total cholesterol (tc), triacylglycerol (tg), low density lipoprotein-cholesterol (ldl-c), and high density lipoprotein-cholesterol (hdl-c)], hormone index [leptin (lep), insulin (ins), ghrelin, adiponectin (adp), and thyroxine (t4)], and 16s rrna sequencing analyses were performed for each group to explore the regulating effect of intestinal flora and the mechanism of weight loss in obese rats. |
2021-02-16 |
2023-08-13 |
rat |
| Zhouya Bai, Jinxia Meng, Xiaojun Huang, Guangjie Wu, Sheng Zuo, Shaoping Ni. Comparative study on antidiabetic function of six legume crude polysaccharides. International journal of biological macromolecules. vol 154. 2021-02-15. PMID:32171833. |
their effects on body weight, fasting blood glucose (fbg), glycosylated serum protein (gsp), serum insulin levels (homa-ir), blood lipids (including total cholesterol (tc), triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), and high-density lipoprotein cholesterol (hdl-c)) were tested. |
2021-02-15 |
2023-08-13 |
mouse |
| Zihang Chen, Simin Wang, Xuexia Luo, Yanhong Yan. Sarcoma-180 tumor affects the quality of oocytes in mice. Oncology letters. vol 21. issue 3. 2021-02-13. PMID:33574920. |
the weight of the mice and ovaries were recorded, and blood glucose, serum insulin, lipopolysaccharide, triglyceride (tg) and total cholesterol (tc) levels were analyzed using the corresponding detection kits. |
2021-02-13 |
2023-08-13 |
mouse |
| Adewumi O Oyabambi, Kehinde S Olaniyi, Ayodele O Soladoye, Lawrence A Olatunj. Suppression of uric acid and lactate production by sodium acetate ameliorates hepatic triglyceride accumulation in fructose-insulin resistant pregnant rats. Environmental toxicology and pharmacology. vol 80. 2021-02-10. PMID:32610186. |
fructose intake resulted in increased body weight gain, liver weight, fluid intake, visceral fat, insulin resistance, fasting blood glucose, insulin, plasma and hepatic tg, total cholesterol, free fatty acid, lipid peroxidation, adenosine deaminase, xanthine oxidase, uric acid, lactate, lactate dehydrogenase, and liver injury marker enzymes. |
2021-02-10 |
2023-08-13 |
rat |
| Rong Fan, Judy Kim, Mikyoung You, David Giraud, Ashley M Toney, Seung-Ho Shin, So-Youn Kim, Kamil Borkowski, John W Newman, Soonkyu Chun. α-Linolenic acid-enriched butter attenuated high fat diet-induced insulin resistance and inflammation by promoting bioconversion of n-3 PUFA and subsequent oxylipin formation. The Journal of nutritional biochemistry. vol 76. 2021-02-08. PMID:31760228. |
the n3bu supplementation attenuated hepatic tg accumulation and adipose tissue inflammation, resulting in improved insulin sensitivity. |
2021-02-08 |
2023-08-13 |
mouse |
| Hua Li, Hye-Mi Park, Hyeon-Seon Ji, Jisu Han, Sang-Kyum Kim, Ho-Yong Park, Tae-Sook Jeon. Phenolic-enriched blueberry-leaf extract attenuates glucose homeostasis, pancreatic β-cell function, and insulin sensitivity in high-fat diet-induced diabetic mice. Nutrition research (New York, N.Y.). vol 73. 2021-02-03. PMID:31923607. |
dietary ble and yme reduced glucose tolerance, body weight, and plasma glucose, glycated hemoglobin, insulin, homeostasis model assessment of insulin resistance, triglyceride (tg), and non-esterified fatty acid levels. |
2021-02-03 |
2023-08-13 |
mouse |