| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suwen Liu, Jincheng Yu, Mengfan Fu, Xinfang Wang, Xuedong Chan. Regulatory effects of hawthorn polyphenols on hyperglycemic, inflammatory, insulin resistance responses, and alleviation of aortic injury in type 2 diabetic rats. Food research international (Ottawa, Ont.). vol 142. 2021-05-27. PMID:33773689. |
our results showed that supplementation with 300 mg hpe/kg body weight over four weeks significantly improved total cholesterol (tc), total triglyceride (tg), insulin, and lipopolysaccharide (lps) levels in diabetic rats (p < 0.01). |
2021-05-27 |
2023-08-13 |
rat |
| André C Carpentie. 100 American journal of physiology. Endocrinology and metabolism. vol 320. issue 4. 2021-05-24. PMID:33522398. |
insulin also regulates adipose tissue fatty acid esterification, glycerol and tg synthesis, lipogenesis, and possibly oxidation, contributing to the trapping of dietary fatty acids in the postprandial state. |
2021-05-24 |
2023-08-13 |
Not clear |
| Annah P Baykal, Elizabeth J Parks, Robert Shamburek, Majid M Syed-Abdul, Shaji Chacko, Elaine Cochran, Megan Startzell, Ahmed M Gharib, Ronald Ouwerkerk, Khaled Z Abd-Elmoniem, Peter J Walter, Mary Walter, Ranganath Muniyappa, Stephanie T Chung, Rebecca J Brow. Leptin decreases de novo lipogenesis in patients with lipodystrophy. JCI insight. vol 5. issue 14. 2021-05-21. PMID:32573497. |
in humans with lipodystrophy, reduced adipose tissue causes lower plasma leptin, insulin resistance, dyslipidemia, and ectopic triglyceride (tg) accumulation. |
2021-05-21 |
2023-08-13 |
Not clear |
| Annah P Baykal, Elizabeth J Parks, Robert Shamburek, Majid M Syed-Abdul, Shaji Chacko, Elaine Cochran, Megan Startzell, Ahmed M Gharib, Ronald Ouwerkerk, Khaled Z Abd-Elmoniem, Peter J Walter, Mary Walter, Ranganath Muniyappa, Stephanie T Chung, Rebecca J Brow. Leptin decreases de novo lipogenesis in patients with lipodystrophy. JCI insight. vol 5. issue 14. 2021-05-21. PMID:32573497. |
we hypothesized that recombinant leptin (metreleptin) for 6 months in 11 patients with lipodystrophy would reduce dnl by decreasing insulin resistance and glycemia, thus reducing circulating tg and hepatic tg. |
2021-05-21 |
2023-08-13 |
Not clear |
| Annah P Baykal, Elizabeth J Parks, Robert Shamburek, Majid M Syed-Abdul, Shaji Chacko, Elaine Cochran, Megan Startzell, Ahmed M Gharib, Ronald Ouwerkerk, Khaled Z Abd-Elmoniem, Peter J Walter, Mary Walter, Ranganath Muniyappa, Stephanie T Chung, Rebecca J Brow. Leptin decreases de novo lipogenesis in patients with lipodystrophy. JCI insight. vol 5. issue 14. 2021-05-21. PMID:32573497. |
metreleptin improved peripheral insulin sensitivity (hyperinsulinemic-euglycemic clamp) and lowered hemoglobin a1c and hepatic tg. |
2021-05-21 |
2023-08-13 |
Not clear |
| Annah P Baykal, Elizabeth J Parks, Robert Shamburek, Majid M Syed-Abdul, Shaji Chacko, Elaine Cochran, Megan Startzell, Ahmed M Gharib, Ronald Ouwerkerk, Khaled Z Abd-Elmoniem, Peter J Walter, Mary Walter, Ranganath Muniyappa, Stephanie T Chung, Rebecca J Brow. Leptin decreases de novo lipogenesis in patients with lipodystrophy. JCI insight. vol 5. issue 14. 2021-05-21. PMID:32573497. |
both before and after metreleptin, dnl positively correlated with insulin resistance, insulin doses, and hepatic tg, supporting the hypothesis that hyperinsulinemia stimulates dnl and that elevated dnl is integral to the pathogenesis of lipodystrophy-associated nafld. |
2021-05-21 |
2023-08-13 |
Not clear |
| Vikas Kumar, Jaswinder Singh, Kiran Bala, Jasbir Sing. Association of resistin (rs3745367) and urotensin II (rs228648 and rs2890565) gene polymorphisms with risk of type 2 diabetes mellitus in Indian population. Molecular biology reports. vol 47. issue 12. 2021-05-19. PMID:33269434. |
glycosylated haemoglobin (hba1c), fasting blood glucose (fbg), high density lipoprotein cholesterol (hdl-c), triglycerides (tg), total cholesterol (chl) and fasting insulin were determined by enzymatic methods. |
2021-05-19 |
2023-08-13 |
human |
| Jie Su, Ting Wang, Mei-Qiu Yan, Jing-Jing Yu, Jian-Bo Xu, Rui-Cheng Zhuge, Huan-Huan Yu, Su-Hong Chen, Gui-Yuan Ly. [Effect of Dendrobii officinalis superfine powder on overeating greasy-induced metabolic hypertension in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 7. 2021-05-14. PMID:33982465. |
the results showed that long-term administration of d. officinalis superfine powder significantly reduced the levels of systolic blood pressure(sbp), diastolic blood pressure(dbp) and mean arterial pressure(mbp) in metabolic hypertension model rats, decreased the levels of total cholesterol(tc), triglyceride(tg), low density lipoprotein cholesterol(ldl-c), glucose(glu), and insulin(ins) levels in blood, increased the contents of high density lipoprotein cholesterol(hdl-c),decreased the lps, crp, il-6 and et-1 levels in blood and increased no content. |
2021-05-14 |
2023-08-13 |
rat |
| Yu Chen, Jingfan Zhang, Ping Li, Cong Liu, Ling L. N1‑methylnicotinamide ameliorates insulin resistance in skeletal muscle of type 2 diabetic mice by activating the SIRT1/PGC‑1α signaling pathway. Molecular medicine reports. vol 23. issue 4. 2021-05-10. PMID:33576435. |
blood glucose, insulin levels, insulin resistance (ir), sensitivity indices and triglyceride (tg) content were detected using elisas. |
2021-05-10 |
2023-08-13 |
mouse |
| Wei Zhao, Chunyan Deng, Qizhen Han, Hansong Xu, Yonghua Che. Carvacrol may alleviate vascular inflammation in diabetic db/db mice. International journal of molecular medicine. vol 46. issue 3. 2021-05-07. PMID:32583003. |
the serum levels of insulin signaling molecules, such as phosphorylated insulin receptor, phosphorylated insulin receptor substrate‑1, insulin, triglyceride (tg) and inflammatory cytokines [tumor necrosis factor‑α, interleukin (il)‑1β, il‑6 and il‑8] were measured by elisa. |
2021-05-07 |
2023-08-13 |
mouse |
| Wei Zhao, Chunyan Deng, Qizhen Han, Hansong Xu, Yonghua Che. Carvacrol may alleviate vascular inflammation in diabetic db/db mice. International journal of molecular medicine. vol 46. issue 3. 2021-05-07. PMID:32583003. |
carvacrol reduced the expression levels of insulin signaling molecules, insulin, tg and inflammatory cytokines in the serum of db/db mice. |
2021-05-07 |
2023-08-13 |
mouse |
| Seyed Ali Hosseini, Khadijeh Hamzavi, Hoda Safarzadeh, Omidreza Saleh. Interactive effect of swimming training and fenugreek ( Archives of physiology and biochemistry. 2021-05-06. PMID:33017260. |
training, fenugreek and training + fenugreek significantly decreased glucose, insulin, insulin resistance, ldl, vldl, tg and tc as well as increased hdl ( |
2021-05-06 |
2023-08-13 |
rat |
| Yanhua Zheng, Jingwei Yu, Chengjie Liang, Shuna Li, Xiaohui Wen, Yanmei L. Characterization on gut microbiome of PCOS rats and its further design by shifts in high-fat diet and dihydrotestosterone induction in PCOS rats. Bioprocess and biosystems engineering. vol 44. issue 5. 2021-05-05. PMID:32157446. |
the fasting blood glucose (fbg), plasma insulin, testosterone, free testosterone, tnf-α, mda, sod, lps, tlr4, tg, tc, hdl-c, and ldl-c levels were measured. |
2021-05-05 |
2023-08-13 |
rat |
| Jahangir Karimian, Sajjad Abedi, Mina Shirinbakhshmasoleh, Farzan Moodi, Vihan Moodi, Abed Ghavam. The effects of quinoa seed supplementation on cardiovascular risk factors: A systematic review and meta-analysis of controlled clinical trials. Phytotherapy research : PTR. vol 35. issue 4. 2021-04-30. PMID:33037704. |
the pooled result showed that quinoa seed supplementation significantly lowered the body weight (wmd: -1.26 kg, 95% ci: -2.35, -0.18, p = .02), waist circumference (wc) (wmd: -1.15 cm, 95% ci: -2.08, -0.21, p = .01), fat mass (fm) (wmd: -0.59%, 95% ci: -1.14, -0.03, p = .03), insulin serum level (wmd: -0.86 pmol/l, 95% ci: -13.38, -1.59, p = .01), triglyceride (tg) (wmd: -7.20 mg/dl, 95% ci: -9.52, -4.87, p < .001), total cholesterol (tc) (wmd: -6.86 mg/dl, 95% ci: -10.64, -3.08, p < .001), and low density lipoprotein (ldl) (wmd: -3.08 mg/dl, 95% ci: -5.13, -1.03, p = .003) levels. |
2021-04-30 |
2023-08-13 |
human |
| Ting Li, Ding-Guo Ruan, Xiao-Yang X. [Effects of different types of exercise on lipid uptake, synthesis and oxidation in skeletal muscles of insulin-resistant rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 2. 2021-04-28. PMID:33903888. |
fasting blood glucose (fbg), insulin (fin), glucagon and lipids, as well as triacylglycerol (tg), free fatty acids (ffa), and the protein expression of fatty acid translocase/cluster of differentiation 36 (fat/cd36), carnitine palmitoyltransferase-1 (cpt-1), stearoyl-coa desaturase-1 (scd-1) and peroxisome proliferators-activated receptors γ (pparγ) in skeletal muscles were measured after 8-week exercise interventions. |
2021-04-28 |
2023-08-13 |
rat |
| Felicja Lwow, A Bohdanowicz-Pawla. Vitamin D and selected cytokine concentrations in postmenopausal women in relation to metabolic disorders and physical activity. Experimental gerontology. vol 141. 2021-04-27. PMID:33038456. |
both anthropometric measurements (bmi, wc, whr) and biochemical measurements (tc, hdl, ldl, tg, aip, glucose, insulin, il-6, tnf-α, adiponectin, leptin) were made, and pa by ipaq were recorded. |
2021-04-27 |
2023-08-13 |
Not clear |
| Dongmei Wei, Chao Yin, Songtao Lu, Juwen Xiong, Lishuang Zhu, Shaoru Yan, Rui Men. The effect of insulin pump combined with ulinastatin on the levels of PCT, TG, PTX-3, and CX3CL1 in patients with diabetic ketoacidosis and pancreatitis. Medicine. vol 100. issue 14. 2021-04-19. PMID:33832077. |
the effect of insulin pump combined with ulinastatin on the levels of pct, tg, ptx-3, and cx3cl1 in patients with diabetic ketoacidosis and pancreatitis. |
2021-04-19 |
2023-08-13 |
human |
| Dongmei Wei, Chao Yin, Songtao Lu, Juwen Xiong, Lishuang Zhu, Shaoru Yan, Rui Men. The effect of insulin pump combined with ulinastatin on the levels of PCT, TG, PTX-3, and CX3CL1 in patients with diabetic ketoacidosis and pancreatitis. Medicine. vol 100. issue 14. 2021-04-19. PMID:33832077. |
the aim of this research is to observe the effect of insulin pump combined with ulinastatin on the levels of procalcitonin (pct), triglycerides (tg), pentraxin-3(ptx-3), and c-x3-c motif chemokine ligand 1 (cx3cl1) in patients with diabetic ketoacidosis and pancreatitis.a total of 72 patients with diabetic ketoacidosis and pancreatitis who were admitted to our hospital from february 2016 to february 2020 were selected as the research subjects. |
2021-04-19 |
2023-08-13 |
human |
| Dongmei Wei, Chao Yin, Songtao Lu, Juwen Xiong, Lishuang Zhu, Shaoru Yan, Rui Men. The effect of insulin pump combined with ulinastatin on the levels of PCT, TG, PTX-3, and CX3CL1 in patients with diabetic ketoacidosis and pancreatitis. Medicine. vol 100. issue 14. 2021-04-19. PMID:33832077. |
after treatment, the total adverse reaction rate of the 2 groups was not significantly different (p > .05), but the total adverse reaction rate of the study group was lower than that of the control group.the combination of insulin pump and ulinastatin in the treatment of patients with diabetic ketoacidosis complicated with acute pancreatitis has a effect, which can shorten the recovery time of clinical symptoms, reduce the levels of pct, tg, ptx-3, and cx3cl1, and has fewer adverse reactions. |
2021-04-19 |
2023-08-13 |
human |
| Minglei Ma, Haibin Liu, Jie Yu, Shuli He, Pingping Li, Chunxiao Ma, Huabing Zhang, Lingling Xu, Fan Ping, Wei Li, Qi Sun, Yuxiu L. Triglyceride is independently correlated with insulin resistance and islet beta cell function: a study in population with different glucose and lipid metabolism states. Lipids in health and disease. vol 19. issue 1. 2021-04-16. PMID:32487177. |
the aim of this study was to explore the relationships among triglyceride (tg), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), oxidative stress indicators, insulin resistance, and beta cell function in populations with different glucose and lipid metabolism states. |
2021-04-16 |
2023-08-13 |
Not clear |