| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fang Fang, Zhang Hong, Zhao Yan, Lin Meilin. [Application of photodynamic therapy combined with compound betamethasone in treatment of hypertrophic scar]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 31. issue 5. 2016-04-26. PMID:26930807. |
to investigate the effect of photodynamic therapy combined with compound betamethasone in the treatment of hypertrophic scar. |
2016-04-26 |
2023-08-13 |
Not clear |
| Peter Kwan, Jie Ding, Edward E Tredge. MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. PloS one. vol 10. issue 4. 2016-04-25. PMID:25837671. |
microrna 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. |
2016-04-25 |
2023-08-13 |
Not clear |
| Peter Kwan, Jie Ding, Edward E Tredge. MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. PloS one. vol 10. issue 4. 2016-04-25. PMID:25837671. |
decorin reduces fibrosis and induces regeneration in many tissues, and is significantly downregulated in hypertrophic scar and normal deep dermal fibroblasts. |
2016-04-25 |
2023-08-13 |
Not clear |
| Peter Kwan, Jie Ding, Edward E Tredge. MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. PloS one. vol 10. issue 4. 2016-04-25. PMID:25837671. |
lower decorin levels were found in hypertrophic scar as compared to normal skin, and in deep as compared to superficial dermis. |
2016-04-25 |
2023-08-13 |
Not clear |
| Peter Kwan, Jie Ding, Edward E Tredge. MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. PloS one. vol 10. issue 4. 2016-04-25. PMID:25837671. |
after finding increased levels of mir-181b in deep dermal fibroblasts, it was demonstrated that tgf-β1 stimulation decreased mir-24 but increased mir-181b and that hypertrophic scar and deep dermis contained increased levels of mir-181b. |
2016-04-25 |
2023-08-13 |
Not clear |
| Peter Kwan, Jie Ding, Edward E Tredge. MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. PloS one. vol 10. issue 4. 2016-04-25. PMID:25837671. |
furthermore, blocking mir-181b reversed tgf-β1 induced decorin downregulation and myofibroblast differentiation in hypertrophic scar fibroblasts, suggesting a potential therapy for hypertrophic scar. |
2016-04-25 |
2023-08-13 |
Not clear |
| Tomohisa Nagasao, Yusuke Hamamoto, Motoki Tamai, Hiroo Kudo, Toshiya Ensako, Tetsukuni Kogure, Naoki Takano, Yoshio Tanak. The "Sea" should not be operated on in scar revision for "Island-Like" scars. Medical hypotheses. vol 85. issue 2. 2016-04-25. PMID:25978927. |
in performing scar revision, care should be taken to prevent the re-sutured wounds from developing hypertrophy again. |
2016-04-25 |
2023-08-13 |
Not clear |
| Xiaozhi Bai, Ting He, Jiaqi Liu, Yunchuan Wang, Lei Fan, Ke Tao, Jihong Shi, Chaowu Tang, Linlin Su, Dahai H. Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway. Experimental dermatology. vol 24. issue 5. 2016-04-22. PMID:25683490. |
loureirin b inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via tgf-β/smad pathway. |
2016-04-22 |
2023-08-13 |
human |
| Xiaozhi Bai, Ting He, Jiaqi Liu, Yunchuan Wang, Lei Fan, Ke Tao, Jihong Shi, Chaowu Tang, Linlin Su, Dahai H. Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway. Experimental dermatology. vol 24. issue 5. 2016-04-22. PMID:25683490. |
to investigate the therapeutic effects of loureirin b on hypertrophic scar (hs), fibroblasts from human hs and normal skin (ns) were isolated. |
2016-04-22 |
2023-08-13 |
human |
| Chen Fan, Yan Xie, Ying Dong, Yonghua Su, Zee Upto. Investigating the potential of Shikonin as a novel hypertrophic scar treatment. Journal of biomedical science. vol 22. 2016-04-18. PMID:26275605. |
investigating the potential of shikonin as a novel hypertrophic scar treatment. |
2016-04-18 |
2023-08-13 |
Not clear |
| Chen Fan, Yan Xie, Ying Dong, Yonghua Su, Zee Upto. Investigating the potential of Shikonin as a novel hypertrophic scar treatment. Journal of biomedical science. vol 22. 2016-04-18. PMID:26275605. |
hypertrophic scarring is a highly prevalent condition clinically and results from a decreased number of apoptotic fibroblasts and over-abundant production of collagen during scar formation following wound healing. |
2016-04-18 |
2023-08-13 |
Not clear |
| Sara Ud-Din, Susan W Volk, Ardeshir Baya. Regenerative healing, scar-free healing and scar formation across the species: current concepts and future perspectives. Experimental dermatology. vol 23. issue 9. 2016-04-14. PMID:24863070. |
notably, excessive cutaneous scar formation, such as hypertrophic and keloid scars, is a species limited clinical entity as it occurs only in humans, although wounds on the distal limbs of horses are also prone to heal with fibroproliferative pathology known as equine exuberant granulation tissue. |
2016-04-14 |
2023-08-13 |
Not clear |
| Hu-jun Wang, Wei-cheng Gao, Shao-lin M. Effect of Abnormal Savda Munziq on hypertrophic scar formation in a rabbit ear model. Chinese journal of integrative medicine. vol 21. issue 7. 2016-04-12. PMID:24449084. |
effect of abnormal savda munziq on hypertrophic scar formation in a rabbit ear model. |
2016-04-12 |
2023-08-12 |
rabbit |
| Hu-jun Wang, Wei-cheng Gao, Shao-lin M. Effect of Abnormal Savda Munziq on hypertrophic scar formation in a rabbit ear model. Chinese journal of integrative medicine. vol 21. issue 7. 2016-04-12. PMID:24449084. |
to investigate whether administrating abnormal savda munziq (asmq), a traditional uighur herbal preparation used for the prevention or treatment of diseases, affects hypertrophic scar (hts) formation by using an established rabbit ear model. |
2016-04-12 |
2023-08-12 |
rabbit |
| C Har. [Cardiovascular diseases in childhood]. Der Radiologe. vol 55. issue 7. 2016-04-08. PMID:26133523. |
arrhythmogenic right ventricular cardiomyopathy requires recognition of fatty infiltration in the myocardium and in hypertrophic cardiomyopathy or myocarditis evidence of scar tissue or fibrosis portends a poor prognosis for the patient. |
2016-04-08 |
2023-08-13 |
Not clear |
| Jun Igarashi, Noboru Fukuda, Takashi Inoue, Shigeki Nakai, Kosuke Saito, Kyoko Fujiwara, Hiroyuki Matsuda, Takahiro Ueno, Yoshiaki Matsumoto, Takayoshi Watanabe, Hiroki Nagase, Toshikazu Bando, Hiroshi Sugiyama, Toshio Itoh, Masayoshi Som. Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model. PloS one. vol 10. issue 5. 2016-04-04. PMID:25938472. |
injection of gb1101 completely inhibited hypertrophic scar formation at 35 days post-incision and inhibited cellular infiltration, tgf-β1 and vimentin staining, and epidermal thickness. |
2016-04-04 |
2023-08-13 |
human |
| Cuiping Zhang, Yan Chen, Xiaobing F. Sweat gland regeneration after burn injury: is stem cell therapy a new hope? Cytotherapy. vol 17. issue 5. 2016-03-28. PMID:25533933. |
the skin of patients with an extensive deep burn injury is repaired by a hypertrophic scar without regeneration of sweat glands and therefore loses the function of perspiration. |
2016-03-28 |
2023-08-13 |
Not clear |
| Christiane Gras, Dominica Ratuszny, Catarina Hadamitzky, Haijiao Zhang, Rainer Blasczyk, Constança Figueired. miR-145 Contributes to Hypertrophic Scarring of the Skin by Inducing Myofibroblast Activity. Molecular medicine (Cambridge, Mass.). vol 21. 2016-03-28. PMID:25876136. |
our data showed not only a threefold increase of mir-145 levels in skin hypertrophic scar tissue but also in transforming growth factor β1 (tgf-β1)-induced skin myofibroblasts compared with healthy skin or nontreated fibroblasts (p < 0.001). |
2016-03-28 |
2023-08-13 |
Not clear |
| Tosan Ehanire, Licheng Ren, Jennifer Bond, Manuel Medina, George Li, Latif Bashirov, Lei Chen, George Kokosis, Mohamed Ibrahim, Angelica Selim, Gerard C Blobe, Howard Levinso. Angiotensin II stimulates canonical TGF-β signaling pathway through angiotensin type 1 receptor to induce granulation tissue contraction. Journal of molecular medicine (Berlin, Germany). vol 93. issue 3. 2016-03-14. PMID:25345602. |
hypertrophic scar contraction (hsc) is caused by granulation tissue contraction propagated by myofibroblast and fibroblast migration and contractility. |
2016-03-14 |
2023-08-13 |
mouse |
| Anne Zhuang, Smita Awasthi, John Naheedy, Andrew C Krakowsk. Intraoperative Ultrasound to Accurately Gauge Scar Thickness and Identify Altered Intrascar Anatomy During Multimodal Revision of a Hypertrophic Chest Wall Burn Scar. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. vol 41. issue 12. 2016-03-14. PMID:26561960. |
intraoperative ultrasound to accurately gauge scar thickness and identify altered intrascar anatomy during multimodal revision of a hypertrophic chest wall burn scar. |
2016-03-14 |
2023-08-13 |
Not clear |