| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Machesney, N Tidman, A Waseem, L Kirby, I Leig. Activated keratinocytes in the epidermis of hypertrophic scars. The American journal of pathology. vol 152. issue 5. 1998-06-02. PMID:9588880. |
the persistence of activated keratinocytes in hypertrophic scar epidermis implicates abnormal epidermal-mesenchymal interactions. |
1998-06-02 |
2023-08-12 |
Not clear |
| D Y Nakamura, B A Costa, R Mann, L H Engra. Silipos neck wraps. The Journal of burn care & rehabilitation. vol 19. issue 2. 1998-05-29. PMID:9556324. |
grafted anterior necks can result in disfiguring hypertrophic scar contractures and wrinkling of the graft. |
1998-05-29 |
2023-08-12 |
Not clear |
| B Liu, M K Connoll. The pathogenesis of cutaneous fibrosis. Seminars in cutaneous medicine and surgery. vol 17. issue 1. 1998-05-07. PMID:9512100. |
cutaneous fibrosis is an integral component of a variety of human disorders including keloids, hypertrophic scar, and most notably, scleroderma. |
1998-05-07 |
2023-08-12 |
human |
| T Murakami, M Yoshioka, R Yumoto, Y Higashi, S Shigeki, Y Ikuta, N Yat. Topical delivery of keloid therapeutic drug, tranilast, by combined use of oleic acid and propylene glycol as a penetration enhancer: evaluation by skin microdialysis in rats. The Journal of pharmacy and pharmacology. vol 50. issue 1. 1998-05-01. PMID:9504434. |
topical delivery of tranilast (n-(3,4-dimethoxycinnamoyl)anthranic acid), an inhibitor of collagen synthesis and a therapeutic drug for keloid and hypertrophic scar, was examined, in rats, with oleic acid alone or a combination of oleic acid and propylene glycol as penetration enhancer. |
1998-05-01 |
2023-08-12 |
rat |
| T Murakami, M Yoshioka, R Yumoto, Y Higashi, S Shigeki, Y Ikuta, N Yat. Topical delivery of keloid therapeutic drug, tranilast, by combined use of oleic acid and propylene glycol as a penetration enhancer: evaluation by skin microdialysis in rats. The Journal of pharmacy and pharmacology. vol 50. issue 1. 1998-05-01. PMID:9504434. |
these results suggest that the topical delivery of tranilast with an absorption enhancer such as a mixture of oleic acid and propylene glycol might be a more effective medication than oral administration of tranilast for the treatment of keloid and hypertrophic scar. |
1998-05-01 |
2023-08-12 |
rat |
| T L Tuan, L S Nichte. The molecular basis of keloid and hypertrophic scar formation. Molecular medicine today. vol 4. issue 1. 1998-04-14. PMID:9494966. |
the molecular basis of keloid and hypertrophic scar formation. |
1998-04-14 |
2023-08-12 |
Not clear |
| T L Tuan, L S Nichte. The molecular basis of keloid and hypertrophic scar formation. Molecular medicine today. vol 4. issue 1. 1998-04-14. PMID:9494966. |
differences between keloids, hypertrophic scars and normal scars include distinct scar appearance, histologic morphology and cellular function in response to growth factors. |
1998-04-14 |
2023-08-12 |
Not clear |
| T L Tuan, L S Nichte. The molecular basis of keloid and hypertrophic scar formation. Molecular medicine today. vol 4. issue 1. 1998-04-14. PMID:9494966. |
this information might assist in the development of efficacious treatment for hypertrophic scar and keloid formation. |
1998-04-14 |
2023-08-12 |
Not clear |
| W H Lewis, K C Wan, S C Lu. Hypertrophic scar and prolonged reaction to BCG vaccination--evidence for common genetic control. British journal of biomedical science. vol 54. issue 3. 1998-03-30. PMID:9499602. |
hypertrophic scar and prolonged reaction to bcg vaccination--evidence for common genetic control. |
1998-03-30 |
2023-08-12 |
Not clear |
| P Schmid, P Itin, G Cherry, C Bi, D A Co. Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar. The American journal of pathology. vol 152. issue 2. 1998-03-06. PMID:9466575. |
enhanced expression of transforming growth factor-beta type i and type ii receptors in wound granulation tissue and hypertrophic scar. |
1998-03-06 |
2023-08-12 |
human |
| P Schmid, P Itin, G Cherry, C Bi, D A Co. Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar. The American journal of pathology. vol 152. issue 2. 1998-03-06. PMID:9466575. |
in the present study we have analyzed and compared, by immunohistochemistry and in situ hybridization, the expression pattern of the r4/alk5 transforming growth factor (tgf)-beta type i receptor (ri) and the tgf-beta type ii receptor (rii) in normal human skin, in wounded skin at various stages during the transition of wound granulation tissue to scar, and in long-persisting post-burn hypertrophic scars. |
1998-03-06 |
2023-08-12 |
human |
| H Giele, K Liddiard, K Booth, F Woo. Anatomical variations in pressures generated by pressure garments. Plastic and reconstructive surgery. vol 101. issue 2. 1998-03-04. PMID:9462773. |
pressure therapy is the predominant means for prophylaxis and treatment of hypertrophic scar. |
1998-03-04 |
2023-08-12 |
human |
| L J Zhou, I Ono, F Kanek. Role of transforming growth factor-beta 1 in fibroblasts derived from normal and hypertrophic scarred skin. Archives of dermatological research. vol 289. issue 11. 1998-02-20. PMID:9444388. |
in order to elucidate the effect of transforming growth factor beta 1 (tgf-beta 1) on normal dermal fibroblasts (ndf) and on fibroblasts derived from hypertrophic scar (hsf) tissue, we compared proliferation, the levels of tgf-beta 1 protein and mrna, the activity of type-i collagen synthesis and collagenase, and the response to recombinant human (rh) tgf-beta 1 in cultures of both types of cells which had been simultaneously collected from the same patients. |
1998-02-20 |
2023-08-12 |
human |
| K Soejima, M Nozaki, K Sasaki, M Takeuchi, N Negish. Reconstruction of burn deformity using artificial dermis combined with thin split-skin grafting. Burns : journal of the International Society for Burn Injuries. vol 23. issue 6. 1998-02-17. PMID:9429031. |
postoperative contraction or hypertrophic scar was observed in three cases, but a soft, favorable quality was obtained in the other nine cases. |
1998-02-17 |
2023-08-12 |
Not clear |
| L J Zhou, M Inoue, I Ono, F Kanek. The mode of action of prostaglandin (PG) I1 analog, SM-10906, on fibroblasts of hypertrophic scars is similar to PGE1 in its potential role of preventing scar formation. Experimental dermatology. vol 6. issue 6. 1998-01-22. PMID:9412820. |
the mode of action of prostaglandin (pg) i1 analog, sm-10906, on fibroblasts of hypertrophic scars is similar to pge1 in its potential role of preventing scar formation. |
1998-01-22 |
2023-08-12 |
human |
| L J Zhou, M Inoue, I Ono, F Kanek. The mode of action of prostaglandin (PG) I1 analog, SM-10906, on fibroblasts of hypertrophic scars is similar to PGE1 in its potential role of preventing scar formation. Experimental dermatology. vol 6. issue 6. 1998-01-22. PMID:9412820. |
the effects of prostaglandin (pg) i1 analog, sm-10906 (sm-6) and pge1 on extracellular matrix formation and the release of cytokines by cultured normal human dermal fibroblasts (ndf) and hypertrophic scar fibroblasts (hsf) were compared in order to evaluate the clinical efficacy of pgs in preventing scar formation. |
1998-01-22 |
2023-08-12 |
human |
| S Zheng, T Li, W Che. [Evaluation of therapeutic effects of moist burn ointment and betadine ointment in treatment of severe burn]. Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns. vol 12. issue 6. 1998-01-20. PMID:9387435. |
at the same time, mbo did not have noticeable effect in inhibiting scar hypertrophy. |
1998-01-20 |
2023-08-12 |
Not clear |
| J Zhu, W Mo, J Zh. [Influence of bitumen on burn wounds and their surrounding skin in guinea-pigs]. Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns. vol 12. issue 6. 1998-01-20. PMID:9387436. |
the third experiment indicated that the wound edges had been seriously destroyed by bitumen, leading to enlargement of the size of the ulcers, and hypertrophy of scar occurred after healing. |
1998-01-20 |
2023-08-12 |
Not clear |
| T S Alster, T B Wes. Treatment of scars: a review. Annals of plastic surgery. vol 39. issue 4. 1997-12-05. PMID:9339286. |
there is no universally accepted treatment modality resulting in permanent hypertrophic or keloid scar ablation. |
1997-12-05 |
2023-08-12 |
Not clear |
| F B Niessen, P H Spauwen, M Ko. The role of suture material in hypertrophic scar formation: Monocryl vs. Vicryl-rapide. Annals of plastic surgery. vol 39. issue 3. 1997-11-25. PMID:9326705. |
the role of suture material in hypertrophic scar formation: monocryl vs. vicryl-rapide. |
1997-11-25 |
2023-08-12 |
Not clear |