| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Injoong Kim, Jon E Mogford, Claudia Witschi, Mehdi Nafissi, Thomas A Musto. Inhibition of prolyl 4-hydroxylase reduces scar hypertrophy in a rabbit model of cutaneous scarring. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 11. issue 5. 2004-03-05. PMID:12950641. |
wounds were harvested at postoperative day 28 and scar hypertrophy quantified by measurement of the scar elevation index. |
2004-03-05 |
2023-08-12 |
rabbit |
| Injoong Kim, Jon E Mogford, Claudia Witschi, Mehdi Nafissi, Thomas A Musto. Inhibition of prolyl 4-hydroxylase reduces scar hypertrophy in a rabbit model of cutaneous scarring. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 11. issue 5. 2004-03-05. PMID:12950641. |
these results suggest that inhibition of prolyl 4-hydroxylase may be a suitable agent for topical treatment for the prevention of hypertrophic scar tissue. |
2004-03-05 |
2023-08-12 |
rabbit |
| Zhi Liang, Loren H Engrav, Pornprom Muangman, Lara A Muffley, Kathy Q Zhu, Gretchen J Carrougher, Robert A Underwood, Nicole S Gibra. Nerve quantification in female red Duroc pig (FRDP) scar compared to human hypertrophic scar. Burns : journal of the International Society for Burn Injuries. vol 30. issue 1. 2004-03-04. PMID:14693087. |
nerve quantification in female red duroc pig (frdp) scar compared to human hypertrophic scar. |
2004-03-04 |
2023-08-12 |
human |
| Zhi Liang, Loren H Engrav, Pornprom Muangman, Lara A Muffley, Kathy Q Zhu, Gretchen J Carrougher, Robert A Underwood, Nicole S Gibra. Nerve quantification in female red Duroc pig (FRDP) scar compared to human hypertrophic scar. Burns : journal of the International Society for Burn Injuries. vol 30. issue 1. 2004-03-04. PMID:14693087. |
a significant impediment to studying hypertrophic scar is the lack of an animal model. |
2004-03-04 |
2023-08-12 |
human |
| Zhi Liang, Loren H Engrav, Pornprom Muangman, Lara A Muffley, Kathy Q Zhu, Gretchen J Carrougher, Robert A Underwood, Nicole S Gibra. Nerve quantification in female red Duroc pig (FRDP) scar compared to human hypertrophic scar. Burns : journal of the International Society for Burn Injuries. vol 30. issue 1. 2004-03-04. PMID:14693087. |
we have confirmed similarities between scarring in the female red duroc pig (frdp) and human hypertrophic scar and conclude that this model warrants validation. |
2004-03-04 |
2023-08-12 |
human |
| Zhi Liang, Loren H Engrav, Pornprom Muangman, Lara A Muffley, Kathy Q Zhu, Gretchen J Carrougher, Robert A Underwood, Nicole S Gibra. Nerve quantification in female red Duroc pig (FRDP) scar compared to human hypertrophic scar. Burns : journal of the International Society for Burn Injuries. vol 30. issue 1. 2004-03-04. PMID:14693087. |
reports have suggested that the cutaneous nervous system may play a role in hypertrophic scar development and several studies have shown nerve density in hypertrophic scar to be increased. |
2004-03-04 |
2023-08-12 |
human |
| Zhi Liang, Loren H Engrav, Pornprom Muangman, Lara A Muffley, Kathy Q Zhu, Gretchen J Carrougher, Robert A Underwood, Nicole S Gibra. Nerve quantification in female red Duroc pig (FRDP) scar compared to human hypertrophic scar. Burns : journal of the International Society for Burn Injuries. vol 30. issue 1. 2004-03-04. PMID:14693087. |
the purpose of this study was to further validate the frdp model of hypertrophic scar by quantifying nerves in frdp tissue and comparing the findings to human hypertrophic scar. |
2004-03-04 |
2023-08-12 |
human |
| Zhi Liang, Loren H Engrav, Pornprom Muangman, Lara A Muffley, Kathy Q Zhu, Gretchen J Carrougher, Robert A Underwood, Nicole S Gibra. Nerve quantification in female red Duroc pig (FRDP) scar compared to human hypertrophic scar. Burns : journal of the International Society for Burn Injuries. vol 30. issue 1. 2004-03-04. PMID:14693087. |
the results demonstrate that nerve tissue is increased in frdp scar tissue and is quite similar to that in human hypertrophic scar and to that described in the literature. |
2004-03-04 |
2023-08-12 |
human |
| Masaki Fujioka, Nishimura Gozo, Miyazato Osamu, Yamamoto Tsuneyuki, Yosida Takehis. Secondary anetoderma overlying pilomatrixomas. Dermatology (Basel, Switzerland). vol 207. issue 3. 2004-02-26. PMID:14571077. |
four large tumors revealed soft, atrophic, pink translucent skin covering a firm subcutaneous mass, and their appearance was similar to that of a keloid or hypertrophic scar. |
2004-02-26 |
2023-08-12 |
Not clear |
| Dongmin Shin, Kyung Won Min. The effect of myofibroblast on contracture of hypertrophic scar. Plastic and reconstructive surgery. vol 113. issue 2. 2004-02-26. PMID:14758226. |
the effect of myofibroblast on contracture of hypertrophic scar. |
2004-02-26 |
2023-08-12 |
Not clear |
| Dongmin Shin, Kyung Won Min. The effect of myofibroblast on contracture of hypertrophic scar. Plastic and reconstructive surgery. vol 113. issue 2. 2004-02-26. PMID:14758226. |
in this research, to compare and directly evaluate the influence on scar contracture of the myofibroblast versus the fibroblast, dermal tissues were taken from 10 patients who had highly contracted hypertrophic scars. |
2004-02-26 |
2023-08-12 |
Not clear |
| Dongmin Shin, Kyung Won Min. The effect of myofibroblast on contracture of hypertrophic scar. Plastic and reconstructive surgery. vol 113. issue 2. 2004-02-26. PMID:14758226. |
by utilizing an in vitro model, the authors have demonstrated that myofibroblasts play a more important role in the contracture of the hypertrophic scar. |
2004-02-26 |
2023-08-12 |
Not clear |
| Ingrid E Roseborough, Mark A Grevious, Raphael C Le. Prevention and treatment of excessive dermal scarring. Journal of the National Medical Association. vol 96. issue 1. 2004-02-19. PMID:14746360. |
there is no consensus on what amount of post-traumatic skin scar formation is "normal" and what should be considered "hypertrophic". |
2004-02-19 |
2023-08-12 |
Not clear |
| Ingrid E Roseborough, Mark A Grevious, Raphael C Le. Prevention and treatment of excessive dermal scarring. Journal of the National Medical Association. vol 96. issue 1. 2004-02-19. PMID:14746360. |
in the world health organization's icd-9, there is no diagnostic code for hypertrophic scar--only keloid is listed. |
2004-02-19 |
2023-08-12 |
Not clear |
| Taro Kono, Ali Ríza Erçöçen, Hiroaki Nakazawa, Takashi Honda, Nobukazu Hayashi, Motohiro Nozak. The flashlamp-pumped pulsed dye laser (585 nm) treatment of hypertrophic scars in Asians. Annals of plastic surgery. vol 51. issue 4. 2004-02-18. PMID:14520063. |
compared with the baseline appearance, hypertrophic scars treated with the pdl showed a satisfactory clinical improvement of 84% (16 of 19), a significant percentage of scar flattening of 58.9 +/- 22.1%, and of erythema elimination of 75.7 +/- 19.9% at month 3 after the last laser treatment. |
2004-02-18 |
2023-08-12 |
Not clear |
| Taro Kono, Ali Ríza Erçöçen, Hiroaki Nakazawa, Takashi Honda, Nobukazu Hayashi, Motohiro Nozak. The flashlamp-pumped pulsed dye laser (585 nm) treatment of hypertrophic scars in Asians. Annals of plastic surgery. vol 51. issue 4. 2004-02-18. PMID:14520063. |
the pdl treatment of hypertrophic scars can effectively improve scar pliability and texture and decrease erythema and associated symptoms. |
2004-02-18 |
2023-08-12 |
Not clear |
| Frank B Niessen, Joost Schalkwijk, Hans Vos, Wim Timen. Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. The Journal of pathology. vol 202. issue 1. 2004-02-09. PMID:14694529. |
hypertrophic scar formation is associated with an increased number of epidermal langerhans cells. |
2004-02-09 |
2023-08-12 |
Not clear |
| Frank B Niessen, Joost Schalkwijk, Hans Vos, Wim Timen. Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. The Journal of pathology. vol 202. issue 1. 2004-02-09. PMID:14694529. |
the exact pathogenesis of hypertrophic scar and keloid formation is still unknown and a good therapy to prevent or treat these scars is lacking. |
2004-02-09 |
2023-08-12 |
Not clear |
| Frank B Niessen, Joost Schalkwijk, Hans Vos, Wim Timen. Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. The Journal of pathology. vol 202. issue 1. 2004-02-09. PMID:14694529. |
the samples were investigated for their number of mast cells, langerhans cells, t-lymphocytes, and macrophages, and the presence of interleukin-4 (il-4) and counter-regulating interferon-gamma (gamma-ifn), in relation to the scar's clinical appearance--normal or hypertrophic. |
2004-02-09 |
2023-08-12 |
Not clear |
| Frank B Niessen, Joost Schalkwijk, Hans Vos, Wim Timen. Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. The Journal of pathology. vol 202. issue 1. 2004-02-09. PMID:14694529. |
in this study, hypertrophic scar formation was significantly associated with an increased number of epidermal langerhans cells (p=0.0001) and significantly (p<0.05) increased expression of epidermal il-4. |
2004-02-09 |
2023-08-12 |
Not clear |