| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eun Jung Lee, Sung Gyun Jung, Byung Chae Cho, Yong Bae Ki. Submuscular augmentation mammaplasty using a perinipple incision. Annals of plastic surgery. vol 52. issue 3. 2004-06-18. PMID:15156986. |
the periareolar approach for submuscular augmentation mammaplasty sometimes shows a widened or hypertrophic scar and distorts the shape of the areolar-skin junction. |
2004-06-18 |
2023-08-12 |
Not clear |
| Bishara S Atiyeh, Christian A Amm, Kusai A El Mus. Improved scar quality following primary and secondary healing of cutaneous wounds. Aesthetic plastic surgery. vol 27. issue 5. 2004-06-14. PMID:14648065. |
hypertrophic scars do not occur spontaneously in animals, which explains the lack of experimental models for the study of pathologic scar modulation. |
2004-06-14 |
2023-08-12 |
Not clear |
| Wei Chen, Xiao-bing Fu, Tong-zhu Su. [Gene expression of stress activated protein kinase and its MAPKs in hypertrophic scar]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 18. issue 1. 2004-06-04. PMID:14768075. |
[gene expression of stress activated protein kinase and its mapks in hypertrophic scar]. |
2004-06-04 |
2023-08-12 |
Not clear |
| Wei Chen, Xiao-bing Fu, Tong-zhu Su. [Gene expression of stress activated protein kinase and its MAPKs in hypertrophic scar]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 18. issue 1. 2004-06-04. PMID:14768075. |
to explore the change of gene expression of stress activated protein kinase (sapk) and its upstream signal-regulated molecule--mitogen activated protein kinases(mapks) (mkk4 and mkk7) in hypertrophic scar and auto-control normal skin. |
2004-06-04 |
2023-08-12 |
Not clear |
| Christopher J Salgado, Samir Mardin. Periareolar approach for the correction of congenital symmastia. Plastic and reconstructive surgery. vol 113. issue 3. 2004-06-03. PMID:15108896. |
the periareolar incision allows for the use of a concealed approach and the avoidance of a central scar that could result in hypertrophy or keloid formation, especially in this patient who is more prone to hypertrophic scarring. |
2004-06-03 |
2023-08-12 |
Not clear |
| M Castañón García-Alix, R Carrasco Torrens, M E Muñoz Fernández, C Grande Moreillo, L Morales Foch. [Treatment with triamcinolone cetonide (trigon-depot) for stenosis after surgery of severe hypospadias]. Actas urologicas espanolas. vol 24. issue 4. 2004-06-01. PMID:14964094. |
in the presence of hard scar tissue it was decided to inject triamcinolone dci acetoide (trigon depot), a long acting steroid, into the segment where the fibrotic narrowing was more severe, in an effort to obtain the same results reported in the treatment of hypertrophic scars and keloids. |
2004-06-01 |
2023-08-12 |
Not clear |
| Luo Lu, Yu-lin Chen, Qing-guo Zhan. [Distribution and expression of transforming growth factor beta and their receptors in hypertrophic scar]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 20. issue 1. 2004-05-27. PMID:15059449. |
[distribution and expression of transforming growth factor beta and their receptors in hypertrophic scar]. |
2004-05-27 |
2023-08-12 |
Not clear |
| Luo Lu, Yu-lin Chen, Qing-guo Zhan. [Distribution and expression of transforming growth factor beta and their receptors in hypertrophic scar]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 20. issue 1. 2004-05-27. PMID:15059449. |
to explore the role of transforming growth factor beta (tgf beta) and their receptors (tgf beta-r) in the pathogenesis of hypertrophic scar. |
2004-05-27 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
gene expression profiles from hypertrophic scar fibroblasts before and after il-6 stimulation. |
2004-05-20 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
the structural rearrangement of collagen fibres in hypertrophic scar causes abnormal contracture, low tensile strength, and raised scars, which cause functional impairment and disfigurement. |
2004-05-20 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
it is hypothesized that changes in the genes of cytokines, extracellular matrix proteins, and proteins regulating programmed cell death are related to hypertrophic scar formation. |
2004-05-20 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
comparison of gene profiles showed an increase of 12 genes in hypertrophic scar fibroblasts compared with normal skin fibroblasts, while the expression of 14 genes decreased. |
2004-05-20 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
thirty-three genes were affected by il-6 treatment in the hypertrophic scar fibroblasts, while 57 genes were affected in normal skin fibroblasts. |
2004-05-20 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
no change in these matrix metalloproteinases could be shown with il-6 stimulation in hypertrophic scar fibroblasts. |
2004-05-20 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
no changes were observed in hypertrophic scar fibroblasts treated with il-6. |
2004-05-20 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
the absence of any up-regulation of mmp-1 and mmp-3 in hypertrophic scar fibroblasts, in response to il-6, suggests that suppression of matrix metalloproteinases may play a role in the excessive accumulation of collagen formed in hypertrophic scars. |
2004-05-20 |
2023-08-12 |
Not clear |
| Mohan R K Dasu, Hal K Hawkins, Robert E Barrow, Hui Xue, David N Herndo. Gene expression profiles from hypertrophic scar fibroblasts before and after IL-6 stimulation. The Journal of pathology. vol 202. issue 4. 2004-05-20. PMID:15095275. |
while the pathogenesis of abnormal hypertrophic scars remains poorly understood, the use of gene expression arrays may prove helpful in identifying the mechanisms responsible for this type of abnormal scar formation and in formulating an effective therapeutic protocol. |
2004-05-20 |
2023-08-12 |
Not clear |
| A El-Ghalbzouri, A J Van Den Bogaerdt, J Kempenaar, M Pone. Human adipose tissue-derived cells delay re-epithelialization in comparison with skin fibroblasts in organotypic skin culture. The British journal of dermatology. vol 150. issue 3. 2004-05-03. PMID:15030326. |
wound healing of deep and extensive burns can induce hypertrophic scar formation. |
2004-05-03 |
2023-08-12 |
human |
| Rupak Mukherjee, Andrea M Parkhurst, Joseph T Mingoia, Sarah E Sweterlitsch, Jennifer S Leiser, G Patricia Escobar, Francis G Spinale, J Philip Sau. Myocardial remodeling after discrete radiofrequency injury: effects of tissue inhibitor of matrix metalloproteinase-1 gene deletion. American journal of physiology. Heart and circulatory physiology. vol 286. issue 4. 2004-04-29. PMID:14630637. |
discrete myocardial rf lesions expand in a time-dependent manner associated with myocyte hypertrophy remote to the scar. |
2004-04-29 |
2023-08-12 |
mouse |
| Thaís Amadeu, André Braune, Carlos Mandarim-de-Lacerda, Luís Cristóvão Porto, Alexis Desmoulière, Andréa Cost. Vascularization pattern in hypertrophic scars and keloids: a stereological analysis. Pathology, research and practice. vol 199. issue 7. 2004-04-27. PMID:14521263. |
wound healing is a complex process that does not always occur harmoniously and may lead to pathological scar development, such as hypertrophic scars and keloids. |
2004-04-27 |
2023-08-12 |
Not clear |