| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maiko Hayashida, Tsuyoshi Miyaoka, Keiko Tsuchie, Tomoko Araki, Muneto Izuhara, Shoko Miura, Misako Kanayama, Koji Ohtsuki, Michiharu Nagahama, Ilhamuddin Abdul Azis, Rostia Arianna Abdullah, Muhammad Alim Jaya, Ryosuke Arauchi, Sadayuki Hashioka, Rei Wake, Toshiko Tsumori, Jun Horiguchi, Arata Oh-Nishi, Masatoshi Inagak. Parvalbumin-positive GABAergic interneurons deficit in the hippocampus in Gunn rats: A possible hyperbilirubinemia-induced animal model of schizophrenia. Heliyon. vol 5. issue 7. 2020-09-28. PMID:31321330. |
importantly, these alterations in gabaergic neurons are not global, which means they are more prevalent among distinct subclasses of interneurons, including those that express the calcium binding protein parvalbumin. |
2020-09-28 |
2023-08-13 |
human |
| Daniel Enterría-Morales, Natalia López-González Del Rey, Javier Blesa, Ivette López-López, Sarah Gallet, Vincent Prévot, José López-Barneo, Xavier d'Anglemont de Tassign. Molecular targets for endogenous glial cell line-derived neurotrophic factor modulation in striatal parvalbumin interneurons. Brain communications. vol 2. issue 2. 2020-09-28. PMID:32954345. |
most of striatal glial cell line-derived neurotrophic factor is synthesized by a subset of gabaergic interneurons characterized by the expression of parvalbumin. |
2020-09-28 |
2023-08-13 |
mouse |
| Smriti Mongia, Tsuyoshi Yamaguchi, Bing Liu, Shiliang Zhang, Huiling Wang, Marisela Morale. The Ventral Tegmental Area has calbindin neurons with the capability to co-release glutamate and dopamine into the nucleus accumbens. The European journal of neuroscience. vol 50. issue 12. 2020-09-23. PMID:31215698. |
while vta dopaminergic and gabaergic neurons have been further characterized by expression of calcium-binding proteins (calbindin, cb; calretinin, cr or parvalbumin, pv), it is unclear whether these proteins are expressed in rat vta glutamatergic neurons. |
2020-09-23 |
2023-08-13 |
rat |
| Kelly M Moench, Michaela R Breach, Cara L Wellma. Prior stress followed by a novel stress challenge results in sex-specific deficits in behavioral flexibility and changes in gene expression in rat medial prefrontal cortex. Hormones and behavior. vol 117. 2020-09-23. PMID:31634476. |
thus, in a separate group of rats, we examined changes in the expression of genes related to glutamatergic (nr1, nr2a, nr2b, glur1) and gabaergic (gad67, parvalbumin, somatostatin) neurotransmission in mpfc after acute and chronic stress, rest, and their combination. |
2020-09-23 |
2023-08-13 |
rat |
| Adrienne Mary Grech, Xin Du, Simon S Murray, Junhua Xiao, Rachel Anne Hil. Sex-specific spatial memory deficits in mice with a conditional TrkB deletion on parvalbumin interneurons. Behavioural brain research. vol 372. 2020-09-17. PMID:31150746. |
cognitive deficits are strongly associated with the dysfunction of gabaergic parvalbumin interneurons (pv-in). |
2020-09-17 |
2023-08-13 |
mouse |
| Stephan F Taylor, Tyler B Grove, Vicki L Ellingrod, Ivy F Ts. The Fragile Brain: Stress Vulnerability, Negative Affect and GABAergic Neurocircuits in Psychosis. Schizophrenia bulletin. vol 45. issue 6. 2020-09-16. PMID:31150555. |
based on postmortem evidence of altered gamma-aminobutyric acid (gaba) function in parvalbumin positive interneurons (pvi), animal models of pvi abnormalities and neuroimaging data with gabaergic challenge, it is suggested that gabaergic disruptions weaken cortical regions, which leads to stress vulnerability and excessive na. |
2020-09-16 |
2023-08-13 |
Not clear |
| Eunchai Kang, Juan Song, Yuting Lin, Jaesuk Park, Jennifer H Lee, Qassim Hussani, Yan Gu, Shaoyu Ge, Weidong Li, Kuei-Sen Hsu, Benedikt Berninger, Kimberly M Christian, Hongjun Song, Guo-Li Min. Interplay between a Mental Disorder Risk Gene and Developmental Polarity Switch of GABA Action Leads to Excitation-Inhibition Imbalance. Cell reports. vol 28. issue 6. 2020-08-31. PMID:31390557. |
following the switch in gabaergic signaling polarity from depolarizing to hyperpolarizing during neuronal maturation, heightened inhibition from excessive parvalbumin |
2020-08-31 |
2023-08-13 |
Not clear |
| Verginia C Cuzon Carlson, Christina M Gremel, David M Lovinge. Gestational alcohol exposure disrupts cognitive function and striatal circuits in adult offspring. Nature communications. vol 11. issue 1. 2020-08-24. PMID:32444624. |
gee mice exhibit decreased gabaergic transmission onto dls projection neurons, including inputs from parvalbumin interneurons, and increased endocannabinoid tone. |
2020-08-24 |
2023-08-13 |
mouse |
| Stephen J Kaar, Ilinca Angelescu, Tiago Reis Marques, Oliver D Howe. Pre-frontal parvalbumin interneurons in schizophrenia: a meta-analysis of post-mortem studies. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 12. 2020-08-17. PMID:31529297. |
parvalbumin interneurons are fast-spiking gabaergic neurons that provide inhibitory control of cortical and subcortical circuits and are thought to be a key locus of the pathophysiology underlying schizophrenia. |
2020-08-17 |
2023-08-13 |
Not clear |
| Samuel J Dienel, David A Lewi. Alterations in cortical interneurons and cognitive function in schizophrenia. Neurobiology of disease. vol 131. 2020-06-29. PMID:29936230. |
here, we review findings from both types of studies which converge on the notions that 1) inhibitory gaba signaling in the pfc, especially between parvalbumin positive gabaergic basket cells and excitatory pyramidal cells, is required for gamma oscillatory activity and working memory function; and 2) disturbances in this signaling contribute to altered gamma oscillations and working memory in schizophrenia. |
2020-06-29 |
2023-08-13 |
Not clear |
| María Sol Kruse, Martín Javier Vadillo, Anabel María Mercedes Miguelez Fernández, Mariana Rey, Bonifacio Silvano Zanutto, Héctor Coirin. Sucrose exposure in juvenile rats produces long-term changes in fear memory and anxiety-like behavior. Psychoneuroendocrinology. vol 104. 2020-05-18. PMID:30928734. |
the calretinin and parvalbumin gabaergic interneurons go through extensive remodeling during youth in the medial prefrontal cortex and the ventral hippocampus. |
2020-05-18 |
2023-08-13 |
rat |
| Danqian Liu, Weifu Li, Chenyan Ma, Weitong Zheng, Yuanyuan Yao, Chak Foon Tso, Peng Zhong, Xi Chen, Jun Ho Song, Woochul Choi, Se-Bum Paik, Hua Han, Yang Da. A common hub for sleep and motor control in the substantia nigra. Science (New York, N.Y.). vol 367. issue 6476. 2020-04-21. PMID:31974254. |
the glutamic acid decarboxylase 2 but not the parvalbumin subset of snr γ-aminobutyric acid (gaba)-releasing (gabaergic) neurons was preferentially active in states of low motor activity and arousal. |
2020-04-21 |
2023-08-13 |
mouse |
| Alejandro Raúl Schmidt, Pablo Ignacio Felipe Inserra, Santiago Andrés Cortasa, Santiago Elías Charif, Sofía Proietto, María Clara Corso, Federico Villarreal, Julia Halperin, César Fabián Loidl, Alfredo Daniel Vitullo, Verónica Berta Dorfma. Structural organization, GABAergic and tyrosine hydroxylase expression in the striatum and globus pallidus of the South American plains vizcacha, Lagostomus maximus (Rodentia, Caviomorpha). Journal of molecular histology. vol 50. issue 6. 2020-04-20. PMID:31515635. |
gabaergic neurons in the matrix of caudate exhibited parvalbumin, calretinin, calbindin, gad65, and nadph-d-immunoreactivity. |
2020-04-20 |
2023-08-13 |
mouse |
| H Trantham-Davidson, A Lavi. Loss of dysbindin-1 affects GABAergic transmission in the PFC. Psychopharmacology. vol 236. issue 11. 2020-01-28. PMID:31201475. |
these results suggest that loss of dysbindin-1 affects gabaergic transmission at pre- and postsynaptic level and decreases parvalbumin markers. |
2020-01-28 |
2023-08-13 |
mouse |
| John F Smiley, Cynthia Bleiwas, Kurt Masiello, Eva Petkova, Judith Betz, Maria Hui, Donald A Wilson, Mariko Sait. Effects of neonatal ethanol on cerebral cortex development through adolescence. Brain structure & function. vol 224. issue 5. 2020-01-02. PMID:31049690. |
gabaergic neurons expressing parvalbumin, calretinin, or somatostatin were reduced by p14, but unlike total neurons the reductions persisted or increased in later ages. |
2020-01-02 |
2023-08-13 |
mouse |
| K. Halasy, R. Miettinen, E. Szabat, T. F. Freun. GABAergic Interneurons are the Major Postsynaptic Targets of Median Raphe Afferents in the Rat Dentate Gyrus. The European journal of neuroscience. vol 4. issue 2. 2019-11-20. PMID:12106377. |
some of the innervated cells were shown to contain calbindin d28k, whereas gabaergic interneurons containing another calcium-binding protein, parvalbumin, were never seen to receive multiple contacts from axons of raphe origin. |
2019-11-20 |
2023-08-12 |
rat |
| Dionysios Xenos, Marija Kamceva, Simone Tomasi, Jessica A Cardin, Michael L Schwartz, Flora M Vaccarin. Loss of TrkB Signaling in Parvalbumin-Expressing Basket Cells Results in Network Activity Disruption and Abnormal Behavior. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 10. 2019-11-06. PMID:28968898. |
the gabaergic system is regulated by the brain-derived neurotrophic factor (bdnf)/tropomyosin-related kinase b (trkb) pathway, but the cell-intrinsic role of trkb signaling in parvalbumin cortical interneuron development and function is unclear. |
2019-11-06 |
2023-08-13 |
mouse |
| Midori Edamatsu, Rinako Miyano, Atsushi Fujikawa, Fuminari Fujii, Tetsuya Hori, Takeshi Sakaba, Toshitaka Oohash. Hapln4/Bral2 is a selective regulator for formation and transmission of GABAergic synapses between Purkinje and deep cerebellar nuclei neurons. Journal of neurochemistry. vol 147. issue 6. 2019-09-27. PMID:30125937. |
pnns are typically found around fast-spiking gabaergic interneurons expressing parvalbumin but interestingly also exist surrounding other neurons, such as the neurons in the dcn and medial nucleus of the trapezoid body, which are the post-synaptic neurons of large axo-somatic synapses adapted for fast signaling. |
2019-09-27 |
2023-08-13 |
mouse |
| Hitomi Tsuiji, Ikuyo Inoue, Mari Takeuchi, Asako Furuya, Yuko Yamakage, Seiji Watanabe, Masato Koike, Mitsuharu Hattori, Koji Yamanak. TDP-43 accelerates age-dependent degeneration of interneurons. Scientific reports. vol 7. issue 1. 2019-07-15. PMID:29097807. |
intriguingly, the aggregates contained some interneuron-specific proteins such as parvalbumin and calretinin, suggesting that gabaergic interneurons were degenerated in these mice. |
2019-07-15 |
2023-08-13 |
mouse |
| Chun-Wai Ma, Pui-Yi Kwan, Kenneth Lap-Kei Wu, Daisy Kwok-Yan Shum, Ying-Shing Cha. Regulatory roles of perineuronal nets and semaphorin 3A in the postnatal maturation of the central vestibular circuitry for graviceptive reflex. Brain structure & function. vol 224. issue 2. 2019-07-01. PMID:30460552. |
similar postponement was observed following inhibition of gabaergic transmission with bicuculline, in line with the reported role of pn in increasing excitability of parvalbumin neurons. |
2019-07-01 |
2023-08-13 |
rat |