| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael Lukas, Inga D Neuman. Nasal application of neuropeptide S reduces anxiety and prolongs memory in rats: social versus non-social effects. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21871467. |
also, the anxiolytic effect of nps on the elevated plus-maze could be confirmed after nasal administration (40 nmol). |
2012-08-13 |
2023-08-12 |
mouse |
| Michael Lukas, Inga D Neuman. Nasal application of neuropeptide S reduces anxiety and prolongs memory in rats: social versus non-social effects. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21871467. |
the effects of icv nps were replicated by nasal application of the neuropeptide. |
2012-08-13 |
2023-08-12 |
mouse |
| Michael Lukas, Inga D Neuman. Nasal application of neuropeptide S reduces anxiety and prolongs memory in rats: social versus non-social effects. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21871467. |
thus, nasal application of nps seems to be a useful method in rodents for screening for behavioral or physiological effects before more specific and time-consuming, intracerebral methods are employed, and may represent a viable therapeutic approach for nps treatment of patients with psychiatric illnesses such as anxiety or panic disorders. |
2012-08-13 |
2023-08-12 |
mouse |
| Sarah Peterson, Julie A Poposki, Deepti R Nagarkar, Regina T Chustz, Anju T Peters, Lydia A Suh, Roderick Carter, James Norton, Kathleen E Harris, Leslie C Grammer, Bruce K Tan, Rakesh K Chandra, David B Conley, Robert C Kern, Robert P Schleimer, Atsushi Kat. Increased expression of CC chemokine ligand 18 in patients with chronic rhinosinusitis with nasal polyps. The Journal of allergy and clinical immunology. vol 129. issue 1. 2012-07-03. PMID:21943944. |
chronic rhinosinusitis with nasal polyps (crswnp) is associated with t(h)2-dominant inflammation, including eosinophilia, which is in contrast to chronic rhinosinusitis (crs) without nasal polyps (nps). |
2012-07-03 |
2023-08-12 |
Not clear |
| Deepa Patel, Sachin Naik, Ambikanandan Misr. Improved transnasal transport and brain uptake of tizanidine HCl-loaded thiolated chitosan nanoparticles for alleviation of pain. Journal of pharmaceutical sciences. vol 101. issue 2. 2012-05-11. PMID:22006260. |
the aim of this study was to prepare and characterize thiolated chitosan (tc) nanoparticles (nps) of tizanidine hcl (tz) and to evaluate its transport across monolayer of rpmi 2650 cells (human nasal septum carcinoma cell line) followed by assessment of their pharmacokinetic and pharmacodynamic attributes, after intranasal (i.n.) |
2012-05-11 |
2023-08-12 |
mouse |
| Deepa Patel, Sachin Naik, Ambikanandan Misr. Improved transnasal transport and brain uptake of tizanidine HCl-loaded thiolated chitosan nanoparticles for alleviation of pain. Journal of pharmaceutical sciences. vol 101. issue 2. 2012-05-11. PMID:22006260. |
nps were prepared using ionotropic gelation and evaluated for mucoadhesion using sheep nasal mucosa for drug permeation and cytotoxicity using monolayer of rpmi 2650 cells. |
2012-05-11 |
2023-08-12 |
mouse |
| Deepa Patel, Sachin Naik, Ambikanandan Misr. Improved transnasal transport and brain uptake of tizanidine HCl-loaded thiolated chitosan nanoparticles for alleviation of pain. Journal of pharmaceutical sciences. vol 101. issue 2. 2012-05-11. PMID:22006260. |
high mucoadhesion and permeation of drug were observed for tc nps with least toxicity to nasal epithelial cells. |
2012-05-11 |
2023-08-12 |
mouse |
| Metin Onerci, Cagdas Elsurer, Elif E Guzel, Attila Dagdevire. Distribution of inflammatory cells, adhesion molecules, intermediate filaments, and chemokine receptors in subgroups of nasal polyp patients. American journal of rhinology & allergy. vol 25. issue 5. 2012-05-09. PMID:21619732. |
the pathogenesis of nasal polyps (nps) is incompletely understood. |
2012-05-09 |
2023-08-12 |
Not clear |
| Ajnacska Rozsasi, Akos Heinemann, Tilman Kec. Cyclooxygenase 2 and lipoxin A₄ in nasal polyps in cystic fibrosis. American journal of rhinology & allergy. vol 25. issue 6. 2012-05-09. PMID:22185734. |
the etiology of nasal polyps (nps) and sinusitis in cystic fibrosis (cf) patients is still unknown. |
2012-05-09 |
2023-08-12 |
Not clear |
| Sevim Bavbek, Berna Dursun, Engin Dursun, Hakan Korkmaz, Durdu Sertkaya Karaso. The prevalence of aspirin hypersensitivity in patients with nasal polyposis and contributing factors. American journal of rhinology & allergy. vol 25. issue 6. 2012-05-09. PMID:22185746. |
aspirin (acetylsalicylic acid [asa]) hypersensitivity is frequent in patients with nasal polyps (nps) and is called aspirin exacerbated respiratory disease, previously known as samter's syndrome. |
2012-05-09 |
2023-08-12 |
Not clear |
| Ji Heui Kim, Hyun Ja Kwon, Yong Ju Jan. Levocetirizine inhibits rhinovirus-induced up-regulation of fibrogenic and angiogenic factors in nasal polyp fibroblasts. American journal of rhinology & allergy. vol 25. issue 6. 2012-05-09. PMID:22185747. |
up-regulation of matrix metalloproteinases (mmps), vascular endothelial growth factor (vegf), and transforming growth factor (tgf) beta, may contribute to the formation of nasal polyps (nps). |
2012-05-09 |
2023-08-12 |
Not clear |
| Xiao-Dan Jiang, Guang-Yu Li, Lin Li, Zhen Dong, Dong-Dong Zh. The characterization of IL-17A expression in patients with chronic rhinosinusitis with nasal polyps. American journal of rhinology & allergy. vol 25. issue 5. 2012-05-09. PMID:22186234. |
more recently, we have shown that the expression of il-17 may be involved in the development of nasal polyps (nps). |
2012-05-09 |
2023-08-12 |
Not clear |
| S Langier, R Landsberg, K Sade, S Kivit. Anti-IL-5 immunomodulates the effect of Staphylococcus aureus enterotoxin on T cell response in nasal polyps. Rhinology. vol 49. issue 5. 2012-03-27. PMID:22125788. |
in this study, we investigated the immunomodulatory effect of saes on cytokine production by t cell obtained from nasal polyps (nps) and examined whether neutralizing interleukin 5 (il-5) can reverse the immunological effect mediated by those toxins. |
2012-03-27 |
2023-08-12 |
Not clear |
| Kosuke Kataoka, Keiko Fujihashi, Yutaka Terao, Rebekah S Gilbert, Shinichi Sekine, Ryoki Kobayashi, Yoshiko Fukuyama, Shigetada Kawabata, Kohtaro Fujihash. Oral-nasopharyngeal dendritic cells mediate T cell-independent IgA class switching on B-1 B cells. PloS one. vol 6. issue 9. 2012-01-26. PMID:21980444. |
native cholera toxin (nct) as a nasal adjuvant was shown to elicit increased levels of t-independent s-iga antibody (ab) responses through il-5- il-5 receptor interactions between cd4+ t cells and iga+ b-1 b cells in murine submandibular glands (smgs) and nasal passages (nps). |
2012-01-26 |
2023-08-12 |
mouse |
| Kosuke Kataoka, Keiko Fujihashi, Yutaka Terao, Rebekah S Gilbert, Shinichi Sekine, Ryoki Kobayashi, Yoshiko Fukuyama, Shigetada Kawabata, Kohtaro Fujihash. Oral-nasopharyngeal dendritic cells mediate T cell-independent IgA class switching on B-1 B cells. PloS one. vol 6. issue 9. 2012-01-26. PMID:21980444. |
high expression levels of activation-induced cytidine deaminase, iα-cμ circulation transcripts and iμ-cα transcripts were seen on b-1 b cells purified from smgs and nps of both tcrβ⁻/⁻ mice and wild-type mice given nasal trinitrophenyl (tnp)-lps plus nct, than in the same tissues of mice given nct or tnp-lps alone. |
2012-01-26 |
2023-08-12 |
mouse |
| Kosuke Kataoka, Keiko Fujihashi, Yutaka Terao, Rebekah S Gilbert, Shinichi Sekine, Ryoki Kobayashi, Yoshiko Fukuyama, Shigetada Kawabata, Kohtaro Fujihash. Oral-nasopharyngeal dendritic cells mediate T cell-independent IgA class switching on B-1 B cells. PloS one. vol 6. issue 9. 2012-01-26. PMID:21980444. |
further, dcs from smgs, nps and nalt of mice given nasal tnp-lps plus nct expressed significantly higher levels of a proliferation-inducing ligand (april) than those in mice given tnp-lps or nct alone, whereas the b-1 b cells in smgs and nps showed elevated levels of transmembrane activator and calcium modulator cyclophilin ligand interactor (taci) expression. |
2012-01-26 |
2023-08-12 |
mouse |
| Philippe Gevaert, Nicholas Van Bruaene, Tom Cattaert, Kristel Van Steen, Thibaut Van Zele, Frederic Acke, Natalie De Ruyck, Katrien Blomme, Ana R Sousa, Richard P Marshall, Claus Bacher. Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis. The Journal of allergy and clinical immunology. vol 128. issue 5. 2011-12-12. PMID:21958585. |
approximately 85% of nasal polyps (nps) in white subjects are characterized by prominent eosinophilia. |
2011-12-12 |
2023-08-12 |
human |
| Judy Gopal, Jayaram Lakshmaiah Narayana, Hui-Fen W. TiO2 nanoparticle assisted mass spectrometry as biosensor of Staphylococcus aureus, key pathogen in nosocomial infections from air, skin surface and human nasal passage. Biosensors & bioelectronics. vol 27. issue 1. 2011-12-07. PMID:21782411. |
for the first time, we have demonstrated the use of mass spectrometry as a biosensor for detecting a clinically important bacterium: staphylococcus aureus in air, nasal passage and skin samples using culture-free, rapid, direct analysis via tio(2) nanoparticles (nps) assisted maldi-ms. |
2011-12-07 |
2023-08-12 |
human |
| Seong Kook Park, Hyeong In Kim, Young Il Yang, Dae Young Hu. Effects of methotrexate on vascular endothelial growth factor, angiopoietin 1, and angiopoietin 2 in nasal polyps. American journal of rhinology & allergy. vol 25. issue 4. 2011-12-02. PMID:21819747. |
the aim of this study was to investigate the effects of mtx on levels of vegf, ang-1, and ang-2 in organ-cultured nasal polyps (nps). |
2011-12-02 |
2023-08-12 |
Not clear |
| Seong Kook Park, Kyung Wook Heo, Dae Young Hur, Young Il Yan. Chitinolytic activity in nasal polyps. American journal of rhinology & allergy. vol 25. issue 1. 2011-11-28. PMID:21711963. |
this study aimed to determine the activities of amcase and cht in nasal polyps (nps), as well as their in situ localization in np tissue. |
2011-11-28 |
2023-08-12 |
Not clear |