| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christina K Kim, Li Ye, Joshua H Jennings, Nandini Pichamoorthy, Daniel D Tang, Ai-Chi W Yoo, Charu Ramakrishnan, Karl Deisserot. Molecular and Circuit-Dynamical Identification of Top-Down Neural Mechanisms for Restraint of Reward Seeking. Cell. vol 170. issue 5. 2017-09-01. PMID:28823561. |
here, we show that a specific subset of superficial mpfc projections to a subfield of nucleus accumbens (nac) neurons naturally encodes the decision to initiate or suppress reward seeking when faced with risk of punishment. |
2017-09-01 |
2023-08-13 |
Not clear |
| Karl T Schmidt, Jason P Schroeder, Stephanie L Foster, Katherine Squires, Brilee M Smith, Elizabeth G Pitts, Michael P Epstein, David Weinshenke. Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortex. Neuropharmacology. vol 119. 2017-08-31. PMID:28392265. |
furthermore, administration of the α1ar antagonist terazosin in the medial prefrontal cortex (mpfc), but not the ventral tegmental area (vta) or nucleus accumbens (nac) shell, attenuated cocaine-primed reinstatement. |
2017-08-31 |
2023-08-13 |
rat |
| Kyosuke Uno, Toh Miyazaki, Kengo Sodeyama, Yoshiaki Miyamoto, Atsumi Nitt. Methamphetamine induces Shati/Nat8L expression in the mouse nucleus accumbens via CREB- and dopamine D1 receptor-dependent mechanism. PloS one. vol 12. issue 3. 2017-08-29. PMID:28319198. |
shati/nat8l significantly increased in the nucleus accumbens (nac) of mice after repeated methamphetamine (meth) treatment. |
2017-08-29 |
2023-08-13 |
mouse |
| Shuntaro Kohnomi, Katsuko Ebihara, Masayuki Kobayash. Suppressive regulation of lateral inhibition between medium spiny neurons via dopamine D Neuroscience letters. vol 636. 2017-08-24. PMID:27793700. |
suppressive regulation of lateral inhibition between medium spiny neurons via dopamine d the nucleus accumbens (nac) shell is closely associated with reward, psychiatric disorders (depression or schizophrenia), and drug abuse. |
2017-08-24 |
2023-08-13 |
Not clear |
| Gil M Lewitus, Sarah C Konefal, Andrew D Greenhalgh, Horia Pribiag, Keanan Augereau, David Stellwage. Microglial TNF-α Suppresses Cocaine-Induced Plasticity and Behavioral Sensitization. Neuron. vol 90. issue 3. 2017-08-22. PMID:27112496. |
repeated administration of cocaine results in the development of behavioral sensitization, accompanied by a decrease in excitatory synaptic strength in the nucleus accumbens (nac) through an unknown mechanism. |
2017-08-22 |
2023-08-13 |
Not clear |
| Nicholas J Edwards, Hugo A Tejeda, Marco Pignatelli, Shiliang Zhang, Ross A McDevitt, Jocelyn Wu, Caroline E Bass, Bernhard Bettler, Marisela Morales, Antonello Bonc. Circuit specificity in the inhibitory architecture of the VTA regulates cocaine-induced behavior. Nature neuroscience. vol 20. issue 3. 2017-08-22. PMID:28114294. |
the nucleus accumbens (nac) provides one of the most prominent projections to the vta; however, recent studies have provided conflicting evidence regarding the function of these inhibitory inputs. |
2017-08-22 |
2023-08-13 |
Not clear |
| Yusuf S Althobaiti, Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Youssef Sar. Effects of repeated high-dose methamphetamine and ceftriaxone post-treatments on tissue content of dopamine and serotonin as well as glutamate and glutamine. Neuroscience letters. vol 634. 2017-08-21. PMID:27702628. |
in this study, wistar rats were used to investigate the effects of meth and cef post-treatment on tissue content of dopamine/5-ht and glutamate/glutamine in the nucleus accumbens (nac) and prefrontal cortex (pfc). |
2017-08-21 |
2023-08-13 |
rat |
| Xincai Ji, Sucharita Saha, Jenya Kolpakova, Melissa Guildford, Andrew R Tapper, Gilles E Marti. Dopamine Receptors Differentially Control Binge Alcohol Drinking-Mediated Synaptic Plasticity of the Core Nucleus Accumbens Direct and Indirect Pathways. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 22. 2017-08-21. PMID:28473645. |
we used drinking in the dark (did) as a model of binge alcohol drinking to assess its effects on spike timing-dependent plasticity (stdp) in medium spiny neurons (msns) of the core nucleus accumbens (nac) by combining patch-clamp recordings with calcium imaging and optogenetics. |
2017-08-21 |
2023-08-13 |
mouse |
| Nicholas M Graziane, Shichao Sun, William J Wright, Daniel Jang, Zheng Liu, Yanhua H Huang, Eric J Nestler, Yu Tian Wang, Oliver M Schlüter, Yan Don. Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses. Nature neuroscience. vol 19. issue 7. 2017-08-18. PMID:27239940. |
exposures to cocaine and morphine produce similar adaptations in nucleus accumbens (nac)-based behaviors, yet produce very different adaptations at nac excitatory synapses. |
2017-08-18 |
2023-08-13 |
Not clear |
| Joseph J Ziminski, Sabine Hessler, Gabriella Margetts-Smith, Meike C Sieburg, Hans S Crombag, Eisuke Koy. Changes in Appetitive Associative Strength Modulates Nucleus Accumbens, But Not Orbitofrontal Cortex Neuronal Ensemble Excitability. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 12. 2017-08-18. PMID:28213443. |
we examined the activation patterns of cue-activated orbitofrontal cortex (ofc) and nucleus accumbens (nac) shell ensembles using wild-type and |
2017-08-18 |
2023-08-13 |
Not clear |
| Ramesh Chandra, T Chase Francis, Hyungwoo Nam, Lace M Riggs, Michel Engeln, Sarah Rudzinskas, Prasad Konkalmatt, Scott J Russo, Gustavo Turecki, Sergio D Iniguez, Mary Kay Lob. Reduced Slc6a15 in Nucleus Accumbens D2-Neurons Underlies Stress Susceptibility. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 27. 2017-08-18. PMID:28576941. |
however, no study examined slc6a15 in the ventral striatum [nucleus accumbens (nac)] in depression. |
2017-08-18 |
2023-08-13 |
mouse |
| Qiwen Hu, Eun Ji Kim, Jian Feng, Gregory R Grant, Elizabeth A Helle. Histone posttranslational modifications predict specific alternative exon subtypes in mammalian brain. PLoS computational biology. vol 13. issue 6. 2017-08-18. PMID:28609483. |
to address this, we have developed novel computational approaches to model the association between alternative splicing and histone posttranslational modifications in the nucleus accumbens (nac), a brain reward region. |
2017-08-18 |
2023-08-13 |
mouse |
| Lauren N Beloate, Azar Omrani, Roger A Adan, Ian C Webb, Lique M Coole. Ventral Tegmental Area Dopamine Cell Activation during Male Rat Sexual Behavior Regulates Neuroplasticity and d-Amphetamine Cross-Sensitization following Sex Abstinence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 38. 2017-08-17. PMID:27656032. |
we previously showed that Δfosb in the nucleus accumbens (nac) is a key mediator of this cross-sensitization, potentially via dopamine receptor activation. |
2017-08-17 |
2023-08-13 |
rat |
| Dan P Covey, Hannah M Dantrassy, Natalie E Zlebnik, Iness Gildish, Joseph F Chee. Compromised Dopaminergic Encoding of Reward Accompanying Suppressed Willingness to Overcome High Effort Costs Is a Prominent Prodromal Characteristic of the Q175 Mouse Model of Huntington's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 18. 2017-08-14. PMID:27147652. |
although dopamine in the nucleus accumbens (nac) critically regulates motivation and altered dopamine signaling is implicated in hd, the nature of dopaminergic deficits and contribution to symptoms in hd is poorly understood. |
2017-08-14 |
2023-08-13 |
mouse |
| Julie A D Dela Cruz, Tricia Coke, Richard J Bodna. Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats. Journal of visualized experiments : JoVE. issue 114. 2017-08-14. PMID:27583636. |
thus, sugar intake elicits da release and increases c-fos-like immunoreactivity (fli) from individual vta da projection zones including the nucleus accumbens (nac), amygdala (amy) and medial prefrontal cortex (mpfc) as well as the dorsal striatum. |
2017-08-14 |
2023-08-13 |
rat |
| Ramesh Chandra, Michel Engeln, T Chase Francis, Prasad Konkalmatt, Dipal Patel, Mary Kay Lob. A Role for Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α in Nucleus Accumbens Neuron Subtypes in Cocaine Action. Biological psychiatry. vol 81. issue 7. 2017-08-14. PMID:27939396. |
in addition, the pgc-1α promoter has binding sites for early growth response 3 (egr3), which plays a dynamic role in cocaine action in nucleus accumbens (nac) medium spiny neuron (msn) subtypes, those enriched in dopamine receptor d |
2017-08-14 |
2023-08-13 |
Not clear |
| Ja Wook Koo, Benoit Labonté, Olivia Engmann, Erin S Calipari, Barbara Juarez, Zachary Lorsch, Jessica J Walsh, Allyson K Friedman, Jordan T Yorgason, Ming-Hu Han, Eric J Nestle. Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress-Induced Depressive Behaviors. Biological psychiatry. vol 80. issue 6. 2017-08-11. PMID:26858215. |
previous work has shown that chronic social defeat stress (csds) induces increased phasic firing of ventral tegmental area (vta) dopamine (da) neurons that project to the nucleus accumbens (nac) selectively in mice that are susceptible to the deleterious effects of the stress. |
2017-08-11 |
2023-08-13 |
mouse |
| Max E Joffe, Brad A Gruete. Cocaine Experience Enhances Thalamo-Accumbens N-Methyl-D-Aspartate Receptor Function. Biological psychiatry. vol 80. issue 9. 2017-08-09. PMID:27209241. |
excitatory synaptic transmission in the nucleus accumbens (nac) is a key biological substrate underlying behavioral responses to psychostimulants and susceptibility to relapse. |
2017-08-09 |
2023-08-13 |
Not clear |
| Andrew F Scheyer, Jessica A Loweth, Daniel T Christian, Jamie Uejima, Rana Rabei, Tuan Le, Hubert Dolubizno, Michael T Stefanik, Conor H Murray, Courtney Sakas, Marina E Wol. AMPA Receptor Plasticity in Accumbens Core Contributes to Incubation of Methamphetamine Craving. Biological psychiatry. vol 80. issue 9. 2017-08-09. PMID:27264310. |
after prolonged withdrawal, incubated cocaine craving depends on strengthening of nucleus accumbens (nac) core synapses through incorporation of ca |
2017-08-09 |
2023-08-13 |
human |
| Michael D Scofield, Hao Li, Benjamin M Siemsen, Kati L Healey, Phuong K Tran, Nicholas Woronoff, Heather A Boger, Peter W Kalivas, Kathryn J Reissne. Cocaine Self-Administration and Extinction Leads to Reduced Glial Fibrillary Acidic Protein Expression and Morphometric Features of Astrocytes in the Nucleus Accumbens Core. Biological psychiatry. vol 80. issue 3. 2017-08-07. PMID:26946381. |
while it has been shown that cocaine experience impairs astroglial glutamate uptake and release in the nucleus accumbens (nac), few studies have explored effects of self-administration on the structure and physiology of astrocytes. |
2017-08-07 |
2023-08-13 |
Not clear |