| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haocheng Zhou, Erik Martinez, Harvey H Lin, Runtao Yang, Jahrane Antonio Dale, Kevin Liu, Dong Huang, Jing Wan. Inhibition of the Prefrontal Projection to the Nucleus Accumbens Enhances Pain Sensitivity and Affect. Frontiers in cellular neuroscience. vol 12. 2020-09-29. PMID:30150924. |
recent studies show that activation of the projections from the pfc to the nucleus accumbens (nac), an important pathway in the brain's reward circuitry, can produce inhibition of both sensory and affective components of pain. |
2020-09-29 |
2023-08-13 |
rat |
| Eugene A Kiyatki. Central and Peripheral Mechanisms Underlying Physiological and Drug-Induced Fluctuations in Brain Oxygen in Freely-Moving Rats. Frontiers in integrative neuroscience. vol 12. 2020-09-29. PMID:30333733. |
first, we show that oxygen levels in the nucleus accumbens (nac) phasically increase following exposure to natural arousing stimuli. |
2020-09-29 |
2023-08-13 |
rat |
| Francesco Lai, Flavia Cucca, Roberto Frau, Francesco Corrias, Michele Schlich, Pierluigi Caboni, Anna Maria Fadda, Valentina Bassare. Systemic Administration of Orexin a Loaded Liposomes Potentiates Nucleus Accumbens Shell Dopamine Release by Sucrose Feeding. Frontiers in psychiatry. vol 9. 2020-09-29. PMID:30559683. |
given the involvement of nucleus accumbens (nac) shell dopamine (da) in motivation for food, we intended to investigate the effect of oxa on the basal and feeding-activated da transmission in the nac shell. |
2020-09-29 |
2023-08-13 |
rat |
| Hojin Shin, Sang-Yoon Lee, Hyun-U Cho, Yoonbae Oh, In Young Kim, Kendall H Lee, Dong Pyo Jang, Hoon-Ki Mi. Fornix Stimulation Induces Metabolic Activity and Dopaminergic Response in the Nucleus Accumbens. Frontiers in neuroscience. vol 13. 2020-09-29. PMID:31708723. |
we previously reported a large-animal study of deep brain stimulation (dbs) in the fornix that found stimulation-induced hemodynamic responses in both the medial limbic and corticolimbic circuits on functional resonance imaging (fmri) and evoked dopamine responses in the nucleus accumbens (nac), as measured by fast-scan cyclic voltammetry (fscv). |
2020-09-29 |
2023-08-13 |
Not clear |
| Sara Schiavi, Daniela Iezzi, Antonia Manduca, Stefano Leone, Francesca Melancia, Carmen Carbone, Michele Petrella, Guido Mannaioni, Alessio Masi, Viviana Trezz. Reward-Related Behavioral, Neurochemical and Electrophysiological Changes in a Rat Model of Autism Based on Prenatal Exposure to Valproic Acid. Frontiers in cellular neuroscience. vol 13. 2020-09-29. PMID:31708750. |
in addition, vpa-exposed rats showed altered expression of dopamine receptors together with inherent hyperexcitability of medium spiny neurons (msns) in the nucleus accumbens (nac). |
2020-09-29 |
2023-08-13 |
rat |
| Rachel Jarvis, Alessandra Tamashiro-Orrego, Vanessa Promes, Leona Tu, Jinyuan Shi, Yongjie Yan. Cocaine Self-administration and Extinction Inversely Alter Neuron to Glia Exosomal Dynamics in the Nucleus Accumbens. Frontiers in cellular neuroscience. vol 13. 2020-09-29. PMID:31998080. |
alteration of glutamatergic synaptic plasticity in the nucleus accumbens (nac) has been implicated in cocaine-seeking behaviors. |
2020-09-29 |
2023-08-13 |
Not clear |
| Juan A Orellana, Waldo Cerpa, Maria F Carvajal, José M Lerma-Cabrera, Eduardo Karahanian, Cesar Osorio-Fuentealba, Rodrigo A Quintanill. New Implications for the Melanocortin System in Alcohol Drinking Behavior in Adolescents: The Glial Dysfunction Hypothesis. Frontiers in cellular neuroscience. vol 11. 2020-09-28. PMID:28424592. |
in particular, we propose that alcohol-induced decrease in α-msh levels may trigger a cascade of glial inflammatory pathways that culminate in altered gliotransmission in the ventral tegmental area and nucleus accumbens (nac). |
2020-09-28 |
2023-08-13 |
Not clear |
| Christina L M Jobson, Justine Renard, Hanna Szkudlarek, Laura G Rosen, Brian Pereira, Daniel J Wright, Walter Rushlow, Steven R Laviolett. Adolescent Nicotine Exposure Induces Dysregulation of Mesocorticolimbic Activity States and Depressive and Anxiety-like Prefrontal Cortical Molecular Phenotypes Persisting into Adulthood. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 7. 2020-09-28. PMID:30124787. |
disturbances in the mesocorticolimbic dopamine (da) system, comprising the prefrontal cortex (pfc), ventral tegmental area (vta), and nucleus accumbens (nac), are correlates of mood and anxiety-related symptoms and this circuitry is strongly influenced by acute or chronic nicotine exposure. |
2020-09-28 |
2023-08-13 |
rat |
| Hyeonsoo Jeong, Laura S Moye, Bruce R Southey, Alvaro G Hernandez, Isaac Dripps, Elena V Romanova, Stanislav S Rubakhin, Jonathan V Sweedler, Amynah A Pradhan, Sandra L Rodriguez-Za. Gene Network Dysregulation in the Trigeminal Ganglia and Nucleus Accumbens of a Model of Chronic Migraine-Associated Hyperalgesia. Frontiers in systems neuroscience. vol 12. 2020-09-28. PMID:30618656. |
the rna-seq profiles of two nervous system regions associated with pain, the trigeminal ganglia (tg) and the nucleus accumbens (nac), were compared in mice receiving chronic ntg treatment relative to control (con) mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Haley N Harris, Yuan B Pen. Evidence and explanation for the involvement of the nucleus accumbens in pain processing. Neural regeneration research. vol 15. issue 4. 2020-09-28. PMID:31638081. |
the nucleus accumbens (nac) is a subcortical brain structure known primarily for its roles in pleasure, reward, and addiction. |
2020-09-28 |
2023-08-13 |
Not clear |
| Yasuhiro Funahashi, Anthony Ariza, Ryosuke Emi, Yifan Xu, Wei Shan, Ko Suzuki, Sachi Kozawa, Rijwan Uddin Ahammad, Mengya Wu, Tetsuya Takano, Yoshimitsu Yura, Keisuke Kuroda, Taku Nagai, Mutsuki Amano, Kiyofumi Yamada, Kozo Kaibuch. Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors. Cell reports. vol 29. issue 10. 2020-09-28. PMID:31801086. |
dopamine (da) activates mitogen-activated protein kinase (mapk) via protein kinase a (pka)/rap1 in medium spiny neurons (msns) expressing the dopamine d1 receptor (d1r) in the nucleus accumbens (nac), thereby regulating reward-related behavior. |
2020-09-28 |
2023-08-13 |
Not clear |
| Arthur Freitas Brandão, Ivan José Magayewski Bonet, Marco Pagliusi, Gabriel Gerardini Zanetti, Nam Pho, Cláudia Herrera Tambeli, Carlos Amilcar Parada, André Schwambach Vieira, Cesar Renato Sartor. Physical Activity Induces Nucleus Accumbens Genes Expression Changes Preventing Chronic Pain Susceptibility Promoted by High-Fat Diet and Sedentary Behavior in Mice. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32038148. |
moreover, differential gene expression in the nucleus accumbens (nac) plays a crucial role in chronic pain susceptibility. |
2020-09-28 |
2023-08-13 |
mouse |
| Chelsea N Brown, Elissa K Fultz, Sami Ferdousian, Sarina Rogers, Elijah Lustig, Ariana Page, John R Shahin, Daniel M Flaherty, Georg Von Jonquieres, Camron D Bryant, Tod E Kippin, Karen K Szumlinsk. Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32116834. |
recently, we discovered an association between genetic vulnerability to ma-taking and increased expression of the glutamate receptor scaffolding protein homer2 within both the shell and core subregions of the nucleus accumbens (nac) and demonstrated a necessary role for homer2 within the shell subregion in ma reward and reinforcement in mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Goksun Demirel, Esra Guzel, Chad J Creighton, Yeter Erol Ozturk, Ceyhun Kucuk, Hızır Asliyuksek, Türkan Yurdu. MDMA Abuse in Relation to MicroRNA Variation in Human Brain Ventral Tegmental Area and Nucleus Accumbens. Iranian journal of pharmaceutical research : IJPR. vol 18. issue 4. 2020-09-28. PMID:32184864. |
the mirna profiling of nucleus accumbens (nac) and ventral tegmental areas (vta) was performed by microarray analysis. |
2020-09-28 |
2023-08-13 |
human |
| Priscila Fernandes Carrara-Nascimento, Lucas Barbosa Hoffmann, Jorge Camilo Flório, Cleopatra Silva Planeta, Rosana Camarin. Effects of Ethanol Exposure During Adolescence or Adulthood on Locomotor Sensitization and Dopamine Levels in the Reward System. Frontiers in behavioral neuroscience. vol 14. 2020-09-28. PMID:32210774. |
dopamine and its metabolites were measured in tissue samples of the prefrontal cortex (pfc), nucleus accumbens (nac) and striatum by hplc analysis. |
2020-09-28 |
2023-08-13 |
mouse |
| Md Taufiq Nasseef, Jai Puneet Singh, Aliza T Ehrlich, Michael McNicholas, Da Woon Park, Weiya Ma, Praveen Kulkarni, Brigitte L Kieffer, Emmanuel Darc. Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice. ACS pharmacology & translational science. vol 2. issue 4. 2020-09-28. PMID:32259060. |
isocortex, nucleus accumbens (nac), pontine reticular nucleus, and periacqueducal gray (pag) components showed the highest number of significant changes. |
2020-09-28 |
2023-08-13 |
mouse |
| Yan Xiao, Huoqing Luo, Wen Z Yang, Yeting Zeng, Yinbo Shen, Xinyan Ni, Zhaomei Shi, Jun Zhong, Ziqi Liang, Xiaoyu Fu, Hongqing Tu, Wenzhi Sun, Wei L Shen, Ji Hu, Jiajun Yan. A Brain Signaling Framework for Stress-Induced Depression and Ketamine Treatment Elucidated by Phosphoproteomics. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32317933. |
we analyzed the phosphoprotein changes induced by chronic unpredictable mild stress (cums) and ketamine treatment in two known mood control centers, the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac). |
2020-09-28 |
2023-08-13 |
mouse |
| Liping Ma, Wenqi Chen, Danfang Yu, Yunyun Ha. Brain-Wide Mapping of Afferent Inputs to Accumbens Nucleus Core Subdomains and Accumbens Nucleus Subnuclei. Frontiers in systems neuroscience. vol 14. 2020-09-28. PMID:32317941. |
the nucleus accumbens (nac) is the ventral part of the striatum and the interface between cognition, emotion, and action. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xi Shen, Rongji Hui, Yixiao Luo, Hailei Yu, Suiyuan Feng, Bing Xie, Haitao Bi, Ewa Galaj, Bin Cong, Chunling Ma, Di We. Berberine Facilitates Extinction of Drug-Associated Behavior and Inhibits Reinstatement of Drug Seeking. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32390837. |
intriguingly, the berberine treatment with or without extinction training altered expression of plasticity-related proteins such as brain-derived neurotrophic factor (bdnf), ampa receptors (glua1 and glua2) in the nucleus accumbens (nac). |
2020-09-28 |
2023-08-13 |
mouse |
| Madoka Anan, Ryoko Higa, Kenshiro Shikano, Masahito Shide, Akinobu Soda, Magdeline E Carrasco Apolinario, Kenji Mori, Toshitaka Shin, Mikiya Miyazato, Hiromitsu Mimata, Takatoshi Hikida, Toshikatsu Hanada, Kazuwa Nakao, Kenji Kangawa, Reiko Hanad. Cocaine has some effect on neuromedin U expressing neurons related to the brain reward system. Heliyon. vol 6. issue 5. 2020-09-28. PMID:32462086. |
in this study, we found that some of cocaine-induced c-fos immunoreactive cells were co-localized with nmu in the nucleus accumbens (nac), caudate putamen (cpu), and basolateral amygdala (bla), which are key brain regions associated with the brain reward system, in wild type mice. |
2020-09-28 |
2023-08-13 |
mouse |