| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenjie Zou, Zhipeng Guo, Longge Suo, Jianping Zhu, Haiyang He, Xiufeng Li, Kewan Wang, Rongqing Che. Nucleus accumbens shell modulates seizure propagation in a mouse temporal lobe epilepsy model. Frontiers in cell and developmental biology. vol 10. 2023-01-02. PMID:36589737. |
the nucleus accumbens (nac) has been suggested as a treatment target for tle as accumulating evidence indicates that the nac, especially its shell, participates in the process of epileptic seizures of patients and animal models with tle. |
2023-01-02 |
2023-08-14 |
mouse |
| Mannan Abdul, Hao-Qi Yan, Wei-Nan Zhao, Xiao-Bin Lyu, Zheng Xu, Xiao-Lu Yu, Yi-Hong Gao, Jun-Li Ca. VTA-NAc glutaminergic projection involves in the regulation of pain and pain-related anxiety. Frontiers in molecular neuroscience. vol 15. 2023-01-02. PMID:36590915. |
besides the established role of dopamine neurons and projections in nociceptive stimuli, the involvement of ventral tegmental area (vta) glutamatergic projections to nucleus accumbens (nac) in pain remains unknown. |
2023-01-02 |
2023-08-14 |
Not clear |
| Xiao-Xing Liu, Fang-Lin Liu, Xin Li, Tang-Sheng Lu, Yi-Xiao Luo, Min Jian, Kai Yuan, Shi-Qiu Meng, Yan-Ping Bao, Jie Shi, Lin Lu, Ying Ha. Novel role of AMPK in cocaine reinforcement via regulating CRTC1. Translational psychiatry. vol 12. issue 1. 2022-12-31. PMID:36587026. |
repeated cocaine exposure causes compensatory neuroadaptations in neurons in the nucleus accumbens (nac), a region that mediates reinforcing effects of drugs. |
2022-12-31 |
2023-08-14 |
rat |
| Yu-Chen Chan, Tai-Li Cho. Effective connectivity of the amygdala during the consumption of erotic, sexual humor, and monetary rewards with a DCM-PEB approach. PloS one. vol 17. issue 12. 2022-12-29. PMID:36580445. |
our results support the importance of the amygdala for sexual humor amusement, the nucleus accumbens (nac) for monetary rewards, and the lateral orbitofrontal cortex (lofc) for erotic pleasure. |
2022-12-29 |
2023-08-14 |
Not clear |
| Jing Wang, Simin Lai, Ting Zhou, Zhihao Xia, Weina Li, Wenqi Sha, Jingjie Liu, Yanjiong Che. Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviors. Journal of neuroinflammation. vol 19. issue 1. 2022-12-29. PMID:36581897. |
neuroinflammation in the nucleus accumbens (nac) is well known to influence the progression of depression. |
2022-12-29 |
2023-08-14 |
Not clear |
| Edwin J C G van den Oord, Lin Y Xie, Min Zhao, Karolina A Aberg, Shaunna L Clar. A single-nucleus transcriptomics study of alcohol use disorder in the nucleus accumbens. Addiction biology. vol 28. issue 1. 2022-12-28. PMID:36577731. |
we therefore assayed the transcriptomes of 32,531 individual nuclei extracted from the nucleus accumbens (nac) of nine donors with aud and nine controls (72% male). |
2022-12-28 |
2023-08-14 |
Not clear |
| Allison M Nieto, Amanda M Catalfio, Helena Papacostas Quintanilla, Yanaira Alonso-Caraballo, Carrie R Ferrari. Transient effects of junk food on NAc core MSN excitability and glutamatergic transmission in obesity-prone female rats. Obesity (Silver Spring, Md.). 2022-12-27. PMID:36575127. |
the nucleus accumbens (nac) plays critical roles in eating and food seeking in rodents and humans. |
2022-12-27 |
2023-08-14 |
rat |
| Ling Lu, Wenhan Yang, Desheng Zhao, Xinwen Wen, Jun Liu, Jixin Liu, Kai Yua. Brain recovery of the NAc fibers and prediction of craving changes in person with heroin addiction: A longitudinal study. Drug and alcohol dependence. vol 243. 2022-12-24. PMID:36565569. |
however, less is known about whether the nucleus accumbens (nac) white matter pathways can recover in pha by prolonged abstinence. |
2022-12-24 |
2023-08-14 |
Not clear |
| Lei Fan, Huan Chen, Yong Liu, Hongwei Hou, Qingyuan H. ERK signaling is required for nicotine-induced conditional place preference by regulating neuroplasticity genes expression in male mice. Pharmacology, biochemistry, and behavior. 2022-12-24. PMID:36565790. |
nicotine is an addictive compound that interacts with nicotinic acetylcholine receptors (nachrs) in the ventral tegmental area (vta), inducing a release of dopamine in the nucleus accumbens (nac). |
2022-12-24 |
2023-08-14 |
mouse |
| Miguel Skirzewski, Oren Princz-Lebel, Liliana German-Castelan, Alycia M Crooks, Gerard Kyungwook Kim, Sophie Henke Tarnow, Amy Reichelt, Sara Memar, Daniel Palmer, Yulong Li, R Jane Rylett, Lisa M Saksida, Vania F Prado, Marco A M Prado, Timothy J Busse. Continuous cholinergic-dopaminergic updating in the nucleus accumbens underlies approaches to reward-predicting cues. Nature communications. vol 13. issue 1. 2022-12-23. PMID:36564387. |
this cued-motivated behaviour depends on the nucleus accumbens (nac). |
2022-12-23 |
2023-08-14 |
mouse |
| Shane A Perrine, Walid F Alsharif, Arman Harutyunyan, Swatabdi Kamal, Nerissa T Viola, Juri G Gelovan. Low- and high-cocaine intake affects the spatial and temporal dynamics of class IIa HDAC expression-activity in the nucleus accumbens and hippocampus of male rats as measured by [18F]TFAHA PET/CT neuroimaging. Addiction neuroscience. vol 4. 2022-12-21. PMID:36540409. |
repeated cocaine alters neuronal function in the nucleus accumbens (nac), a brain region involved in cocaine taking, and in hippocampus (hc), known for contextual and associative learning. |
2022-12-21 |
2023-08-14 |
rat |
| Hong Zhou, Jiayu Zhu, Jie Jia, Wei Xiang, Hualing Peng, Yuejin Zhang, Bo Liu, Yangling Mu, Yisheng L. The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus. Neurobiology of stress. vol 21. 2022-12-19. PMID:36532368. |
the nucleus accumbens (nac) is a crucial region in the reward circuit and is related to anhedonia, the pivotal symptom of major depression disorder (mdd). |
2022-12-19 |
2023-08-14 |
mouse |
| Alaa M Hammad, Asma'a Naser, Haneen Amawi, F Scott Hall, Amit K Tiwari, Bahaa Al-Tra. Effect of Amoxicillin/Clavulanic acid in attenuating Pregabalin-induced Condition Place Preference. Behavioural brain research. 2022-12-05. PMID:36470419. |
moreover, like other drugs of abuse, pregabalin also produced alterations in glutamate homeostasis, reducing the mrna expression of slc1a2 and slc7a11 in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc). |
2022-12-05 |
2023-08-14 |
Not clear |
| Lucia Carboni, Laura Rullo, Francesca Felicia Caputi, Serena Stamatakos, Sanzio Candeletti, Patrizia Romuald. Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy. International journal of molecular sciences. vol 23. issue 22. 2022-11-26. PMID:36430520. |
mrna expression of growth factor and circadian rhythm genes was evaluated by qpcr in the prefrontal cortex (pfcx), hippocampus, nucleus accumbens (nac), amygdala, and hypothalamus. |
2022-11-26 |
2023-08-14 |
rat |
| Yu-Chen Chan, Chen-Ya Wang, Tai-Li Cho. Money or Funny: Effective Connectivity during Service Recovery with a DCM-PEB Approach. Biological psychology. 2022-11-26. PMID:36435295. |
the findings support the importance of the nucleus accumbens (nac) in the monetary compensation (mh and ma) conditions and the amygdala in the non-monetary compensation (h and con) conditions. |
2022-11-26 |
2023-08-14 |
Not clear |
| Giuseppe Aceto, Luca Nardella, Giacomo Lazzarino, Barbara Tavazzi, Alessia Bertozzi, Simona Nanni, Claudia Colussi, Marcello D'Ascenzo, Claudio Grass. Acute restraint stress impairs histamine type 2 receptor ability to increase the excitability of medium spiny neurons in the nucleus accumbens. Neurobiology of disease. 2022-11-25. PMID:36427690. |
histamine, a monoamine implicated in stress-related arousal states, is synthesized in neurons exclusively located in the hypothalamic tuberomammillary nucleus (tmn) from where they diffusely innervate striatal and mesolimbic networks including the nucleus accumbens (nac), a vital node in the limbic loop. |
2022-11-25 |
2023-08-14 |
mouse |
| Svetlana Bryant, Julie-Anne Balouek, Luke T Geiger, David J Barker, Catherine J Peñ. Neuropathic pain as a trigger for histone modifications in limbic circuitry. Genes, brain, and behavior. 2022-11-22. PMID:36412100. |
to better understand how such enduring transcriptional changes might be regulated within brain structures associated with processing of pain or affect, we examined epigenetic modifications involved with active or permissive transcriptional states (histone h3 lysine 4 mono and trimethylation, and histone h3 lysine 27 acetylation) in periaqueductal gray (pag), lateral hypothalamus (lh), nucleus accumbens (nac), and ventral tegmental area (vta) 5 weeks after sciatic nerve injury in mice to model chronic pain. |
2022-11-22 |
2023-08-14 |
mouse |
| He Chen, Limei Chen, Zhirong Yuan, Jiajie Yuan, Yitong Li, Yuesi Xu, Jieyi Wu, Lu Zhang, Guohua Wang, Juan L. Glutamate receptor-interacting protein 1 in D1- and D2-dopamine receptor-expressing medium spiny neurons differentially regulates cocaine acquisition, reinstatement, and associated spine plasticity. Frontiers in cellular neuroscience. vol 16. 2022-11-21. PMID:36406750. |
the nucleus accumbens (nac) is involved in the expression of cocaine addictive phenotypes, including acquisition, extinction, and reinstatement. |
2022-11-21 |
2023-08-14 |
Not clear |
| Wanqi Che. Neural circuits provide insights into reward and aversion. Frontiers in neural circuits. vol 16. 2022-11-17. PMID:36389177. |
the aim of this paper is to summarize the latest findings on the mechanisms of the neural circuits associated with reward and aversion in a review of previous studies with a focus on the ventral tegmental area (vta), nucleus accumbens (nac), and basal forebrain (bf). |
2022-11-17 |
2023-08-14 |
Not clear |
| Xuansong Mao, Kolter B Grigsby, Taylor J Kelty, Nathan R Kerr, Thomas E Childs, Frank W Boot. Transcriptomic analysis reveals novel molecular signaling networks in response to nucleus accumbens AP-1 inhibition in rats selectively bred for low voluntary wheel running behavior. Neuroscience. 2022-11-17. PMID:36395916. |
transcriptome analysis of the nucleus accumbens (nac; a brain region critical for pa reward and motivation) was performed to further determine molecular responses to intra-nac ap-1 inhibition in these rat lines. |
2022-11-17 |
2023-08-14 |
rat |