| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R D Mayfield, G Larson, N R Zahnise. Cocaine-induced behavioral sensitization and D1 dopamine receptor function in rat nucleus accumbens and striatum. Brain research. vol 573. issue 2. 1992-09-18. PMID:1387030. |
based on electrophysiological data showing that repeated cocaine administration produces persistent enhancement of d1 dopamine (da) receptor-mediated responses in nucleus accumbens (nac), we investigated whether changes in neurochemical properties of these receptors resulted when rats were injected with cocaine (15 mg/kg) for 6 days followed by a 7-day abstinence period. |
1992-09-18 |
2023-08-11 |
rat |
| B G Hoebel, G P Mark, H L Wes. Conditioned release of neurotransmitters as measured by microdialysis. Clinical neuropharmacology. vol 15 Suppl 1 Pt A. 1992-09-14. PMID:1354074. |
extracellular dopamine (da) in the nucleus accumbens (nac) was released (a) during eating and (b) by a conditioned taste associated with intragastric infusion of carbohydrate, but (c) da decreased in response to a taste that had been paired with nausea. |
1992-09-14 |
2023-08-11 |
Not clear |
| D Nakahara, K Fuchikami, N Ozaki, T Iwasaki, T Nagats. Differential effect of self-stimulation on dopamine release and metabolism in the rat medial frontal cortex, nucleus accumbens and striatum studied by in vivo microdialysis. Brain research. vol 574. issue 1-2. 1992-08-28. PMID:1638391. |
changes in the extracellular levels of dopamine (da) and its metabolites in the dopaminergic terminal regions, the medial frontal cortex (mfc), nucleus accumbens (nac), and striatum (str), were measured by microdialysis during self-stimulation of the medial forebrain bundle (mfb) in rats pretreated with the da uptake inhibitor, nomifensine (1 mg/kg, i.p.). |
1992-08-28 |
2023-08-11 |
rat |
| B Hope, B Kosofsky, S E Hyman, E J Nestle. Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 13. 1992-08-14. PMID:1631058. |
chronic treatment of rats with cocaine leads to long-term biochemical changes in the nucleus accumbens (nac), a brain region implicated in mediating the reinforcing effects of cocaine and other drugs of abuse. |
1992-08-14 |
2023-08-11 |
rat |
| L Pulvirenti, N R Swerdlow, G F Koo. Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine. Pharmacology, biochemistry, and behavior. vol 40. issue 4. 1992-06-30. PMID:1687766. |
glutamatergic afferents to the nucleus accumbens (nac) have been suggested to modulate psychostimulant-induced locomotor activation. |
1992-06-30 |
2023-08-11 |
rat |
| L Pulvirenti, N R Swerdlow, G F Koo. Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine. Pharmacology, biochemistry, and behavior. vol 40. issue 4. 1992-06-30. PMID:1687766. |
the purpose of this study was 1) to determine the importance of nucleus accumbens n-methyl-d-aspartate (nmda) glutamate receptors in the control of psychostimulant-induced locomotion, 2) to determine whether nmda receptor modulation of psychostimulant-induced locomotion occurs presynaptic to or postsynaptic to nac dopamine terminals, and 3) to determine whether nmda receptors also modulate opiate- and caffeine-induced locomotor activation. |
1992-06-30 |
2023-08-11 |
rat |
| E Pothos, P Rada, G P Mark, B G Hoebe. Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipitated withdrawal and clonidine treatment. Brain research. vol 566. issue 1-2. 1992-06-23. PMID:1814554. |
this study shows the effect of opiate withdrawal on dopamine (da) in the nucleus accumbens (nac). |
1992-06-23 |
2023-08-11 |
rat |
| Y Takamatsu, H Yamamoto, O O Ogunremi, I Matsuzaki, T Moroj. The effects of corticotropin-releasing hormone on peptidergic neurons in the rat forebrain. Neuropeptides. vol 20. issue 4. 1992-06-11. PMID:1687480. |
the icv administration of 1 and 10 micrograms crh caused a marked reduction in cck-like immunoreactivity (cck-li), npy-li and som-li in the medial frontal cortex (mfc) and anterior cingulate cortex (ant.cc), whereas it induced an increment of npy-li in the nucleus accumbens (nac) and striatum. |
1992-06-11 |
2023-08-11 |
rat |
| G P Mark, P Rada, E Pothos, B G Hoebe. Effects of feeding and drinking on acetylcholine release in the nucleus accumbens, striatum, and hippocampus of freely behaving rats. Journal of neurochemistry. vol 58. issue 6. 1992-06-04. PMID:1573406. |
extracellular levels of acetylcholine (ach) were measured in the nucleus accumbens (nac), striatum (str), and hippocampus (hipp) using microdialysis in 30-min intervals before, during, and after free-feeding in 20-h food-deprived rats. |
1992-06-04 |
2023-08-11 |
rat |
| G S Robertson, J G Pfaus, L J Atkinson, H Matsumura, A G Phillips, H C Fibige. Sexual behavior increases c-fos expression in the forebrain of the male rat. Brain research. vol 564. issue 2. 1992-06-04. PMID:1810635. |
psychomotor stimulants increase the release of dopamine from the terminals of nigrostriatal and mesolimbic neurons and enhance fos immunoreactivity in the striatum and nucleus accumbens (nac). |
1992-06-04 |
2023-08-11 |
rat |
| P Rada, E Pothos, G P Mark, B G Hoebe. Microdialysis evidence that acetylcholine in the nucleus accumbens is involved in morphine withdrawal and its treatment with clonidine. Brain research. vol 561. issue 2. 1992-04-24. PMID:1802350. |
this study used microdialysis to measure changes in extracellular acetylcholine (ach) content in the nucleus accumbens (nac) of freely moving rats during acute and chronic morphine treatment, and following naloxone-precipitated withdrawal. |
1992-04-24 |
2023-08-11 |
rat |
| G G Nomikos, A P Zis, G Damsma, H C Fibige. Effects of chronic electroconvulsive shock on interstitial concentrations of dopamine in the nucleus accumbens. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1724565. |
the present experiments investigated the effects of acute and chronic ecs on interstitial concentrations of dopamine (da) in the nucleus accumbens (nac) using in vivo microdialysis in awake freely moving rats. |
1992-04-07 |
2023-08-11 |
rat |
| L Hernandez, N A Guzman, B G Hoebe. Bidirectional microdialysis in vivo shows differential dopaminergic potency of cocaine, procaine and lidocaine in the nucleus accumbens using capillary electrophoresis for calibration of drug outward diffusion. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1796132. |
this suggests that in vivo about 68 nmol cocaine diffused into the nucleus accumbens (nac) during the 20 min. |
1992-04-07 |
2023-08-11 |
rat |
| J A Stamford, R Muscat, J J O'Connor, J Patel, S J Trout, W J Wieczorek, Z L Kruk, P Willne. Voltammetric evidence that subsensitivity to reward following chronic mild stress is associated with increased release of mesolimbic dopamine. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1796133. |
dopamine (da) release in the nucleus accumbens (nac) and caudate putamen (cpu) was measured in vivo using fast cyclic voltammetry, following electrical stimulation of the medial forebrain bundle. |
1992-04-07 |
2023-08-11 |
rat |
| H Nakamura, T Moroji, S Nohara, H Nakamura, A Okad. Activation of cerebral dopaminergic systems by noise and whole-body vibration. Environmental research. vol 57. issue 1. 1992-03-20. PMID:1740092. |
noise and whole-body vibration increased both cor and da turnover rates (shown by an increase of homovanillic acid (hva) and/or hva/da ratio) in the frontal cortex (fc) and the nucleus accumbens (nac). |
1992-03-20 |
2023-08-11 |
rat |
| J L Cadet, K Kujirai, S Przedborsk. Bilateral modulation of [3H]neurotensin binding by unilateral intrastriatal 6-hydroxydopamine injections: evidence from a receptor autoradiographic study. Brain research. vol 564. issue 1. 1992-03-12. PMID:1663814. |
intrastriatal injections of 6-hydroxydopamine which cause almost complete destruction of the mesostriatal dopaminergic pathway also caused a marked loss of neurotensin receptors in the caudate-putamen (cpu), the nucleus accumbens (nac) and in the olfactory tubercle (ot). |
1992-03-12 |
2023-08-11 |
rat |
| C A Leslie, M W Robertson, A J Cutler, J P Bennet. Postnatal development of D1 dopamine receptors in the medial prefrontal cortex, striatum and nucleus accumbens of normal and neonatal 6-hydroxydopamine treated rats: a quantitative autoradiographic analysis. Brain research. Developmental brain research. vol 62. issue 1. 1992-02-12. PMID:1836980. |
the postnatal development of dopamine (da) d1 receptors in the medial prefrontal cortex (mpfc), striatum (str) and nucleus accumbens (nac) of control and perinatally 6-hydroxydopamine (6-ohda) lesioned rats was examined using quantitative autoradiography of 3h-sch 23390 binding. |
1992-02-12 |
2023-08-11 |
rat |
| J A Angulo, H Coirini, M Ledoux, M Schumache. Regulation by dopaminergic neurotransmission of dopamine D2 mRNA and receptor levels in the striatum and nucleus accumbens of the rat. Brain research. Molecular brain research. vol 11. issue 2. 1992-02-06. PMID:1661813. |
by day 8 of haloperidol treatment, d2 mrna and receptor levels were decreased (up to 20%) in the medial and anterior aspects of the caudate-putamen (mcpu and acpu) and the nucleus accumbens (nac). |
1992-02-06 |
2023-08-11 |
rat |
| P Rada, G P Mark, E Pothos, B G Hoebe. Systemic morphine simultaneously decreases extracellular acetylcholine and increases dopamine in the nucleus accumbens of freely moving rats. Neuropharmacology. vol 30. issue 10. 1992-02-04. PMID:1758589. |
microdialysis was used to measure extracellular levels of acetylcholine (ach) and dopamine (da) simultaneously in the nucleus accumbens (nac) of freely moving rats. |
1992-02-04 |
2023-08-11 |
rat |
| P A Johansen, X T Hu, F J Whit. Relationship between D1 dopamine receptors, adenylate cyclase, and the electrophysiological responses of rat nucleus accumbens neurons. Journal of neural transmission. General section. vol 86. issue 2. 1992-01-02. PMID:1683241. |
the electrophysiological effects of three selective d1 dopamine (da) receptor agonists, which exhibit different potencies and efficacies for stimulation of adenylate cyclase, were compared in the rat nucleus accumbens (nac) using single unit recording and microiontophoretic techniques. |
1992-01-02 |
2023-08-11 |
rat |