| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F I Tarazi, A Campbell, S K Yeghiayan, R J Baldessarin. Localization of ionotropic glutamate receptors in caudate-putamen and nucleus accumbens septi of rat brain: comparison of NMDA, AMPA, and kainate receptors. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723793. |
changes in binding of selective radioligands at nmda ([3h]mk-801), ampa ([3h]cnqx), and kainate ([3h]kainic acid) glutamate (glu) ionotropic receptors in rat caudate-putamen (cpu) and nucleus accumbens (nac) were examined by quantitative autoradiography following: 1) unilateral surgical ablation of frontal cerebral cortex to remove descending corticostriatal glu projections, 2) unilateral injection of kainic acid (ka) into cpu or nac to degenerate local intrinsic neurons, or 3) unilateral injections of 6-hydroxydopamine (6-oh-da) into substantia nigra to degenerate ascending nigrostriatal dopamine (da) projections. |
1998-11-16 |
2023-08-12 |
rat |
| T A Patterson, M D Brot, A Zavosh, J O Schenk, P Szot, D P Figlewic. Food deprivation decreases mRNA and activity of the rat dopamine transporter. Neuroendocrinology. vol 68. issue 1. 1998-10-23. PMID:9695934. |
binding of a specific high-affinity dat ligand (125i-rti-121) to membranes from brain regions of fasted or free-feeding rats provided an estimate of dat protein, which was unchanged in both of the major terminal projection fields, the striatum and nucleus accumbens (nac). |
1998-10-23 |
2023-08-12 |
rat |
| F I Tarazi, S K Yeghiayan, J L Neumeyer, R J Baldessarin. Medial prefrontal cortical D2 and striatolimbic D4 dopamine receptors: common targets for typical and atypical antipsychotic drugs. Progress in neuro-psychopharmacology & biological psychiatry. vol 22. issue 4. 1998-10-13. PMID:9682281. |
d2 receptors in caudate-putamen (cpu), nucleus accumbens (nac) and olfactory tubercle (ot) were significantly increased by long-term treatment with fluphenazine, but not with clozapine or s[+]-npa. |
1998-10-13 |
2023-08-12 |
Not clear |
| O Manzoni, D Pujalte, J Williams, J Bockaer. Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 19. 1998-10-09. PMID:9742166. |
the nucleus accumbens (nac) is a site mediating the rewarding properties of drugs of abuse, such as cocaine, amphetamine, opiates, nicotine, and alcohol (wise and bozarth, 1987; koob, 1992; samson andharris, 1992; woolverton and johnson, 1992; self and nestler, 1995; pontieri et al., 1996). |
1998-10-09 |
2023-08-12 |
Not clear |
| T Watanabe, K Morimoto, M Nakamura, H Suwak. Modification of behavioral responses induced by electrical stimulation of the ventral tegmental area in rats. Behavioural brain research. vol 93. issue 1-2. 1998-09-24. PMID:9659994. |
similar responses were obtained when the nucleus accumbens (nac) or prefrontal cortex (pfc) were stimulated. |
1998-09-24 |
2023-08-12 |
rat |
| C Heidbreder, J Feldo. Amphetamine-induced neurochemical and locomotor responses are expressed differentially across the anteroposterior axis of the core and shell subterritories of the nucleus accumbens. Synapse (New York, N.Y.). vol 29. issue 4. 1998-09-24. PMID:9661249. |
the administration of psychostimulants increases dopamine (da) release within the nucleus accumbens (nac), a terminal projection site of mesolimbic da neurons, originating in the ventral tegmental area (vta). |
1998-09-24 |
2023-08-12 |
Not clear |
| B D Kretschmer, M Koc. The ventral pallidum mediates disruption of prepulse inhibition of the acoustic startle response induced by dopamine agonists, but not by NMDA antagonists. Brain research. vol 798. issue 1-2. 1998-09-11. PMID:9666129. |
the neuronal circuitry which regulates ppi consists of cortico-limbic brain structures where the nucleus accumbens (nac) plays a key role. |
1998-09-11 |
2023-08-12 |
rat |
| D Wei, I M Maisonneuve, M E Kuehne, S D Glic. Acute iboga alkaloid effects on extracellular serotonin (5-HT) levels in nucleus accumbens and striatum in rats. Brain research. vol 800. issue 2. 1998-09-04. PMID:9685673. |
in vivo microdialysis and hplc (microbore) were used to determine acute changes in extracellular serotonin levels in nucleus accumbens (nac) and striatum (str) after both i.p. |
1998-09-04 |
2023-08-12 |
rat |
| D A Cory-Slechta, D J O'Mara, B J Brocke. Nucleus accumbens dopaminergic medication of fixed interval schedule-controlled behavior and its modulation by low-level lead exposure. The Journal of pharmacology and experimental therapeutics. vol 286. issue 2. 1998-09-02. PMID:9694936. |
to examine the assertion that changes in nucleus accumbens (nac) dopamine (da) activity serve as a mechanism of lead (pb)-induced disruption of fixed interval (fi) schedule-controlled behavior, the effects of intra-nac administration of the irreversible da antagonist eedq (n-ethoxycarbonyl-2-ethoxy-1,2-dihyroquinoline) and of dopamine itself on fi performance were compared in rats that had been chronically exposed to 0, 50 or 500 ppm pb acetate in drinking water from weaning. |
1998-09-02 |
2023-08-12 |
rat |
| N Guo, S R Vincent, H C Fibige. Phenotypic characterization of neuroleptic-sensitive neurons in the forebrain: contrasting targets of haloperidol and clozapine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 19. issue 2. 1998-08-21. PMID:9629567. |
similarly, in the nucleus accumbens (nac) and lateral septal nucleus (lsn), the majority of clozapine-induced fli neurons express d3 receptor mrna (nac 69%; ls 73%). |
1998-08-21 |
2023-08-12 |
Not clear |
| T J De Vries, A R Cools, T S Shippenber. Infusion of a D-1 receptor agonist into the nucleus accumbens enhances cocaine-induced behavioural sensitization. Neuroreport. vol 9. issue 8. 1998-08-13. PMID:9665597. |
the present study was designed to evaluate the effect of dopamine (da) d-1 receptor activation in the nucleus accumbens (nac) on the locomotor sensitizing effects of repeated intra-accumbens (intra-nac) infusions of cocaine. |
1998-08-13 |
2023-08-12 |
Not clear |
| B T Hop. Cocaine and the AP-1 transcription factor complex. Annals of the New York Academy of Sciences. vol 844. 1998-08-13. PMID:9668659. |
in the striatum (str) and nucleus accumbens (nac) of rats. |
1998-08-13 |
2023-08-12 |
rat |
| S M Baca, B K Lipska, M F Egan, S E Bachus, J N Ferguson, T M Hyd. Effects of prefrontal cortical lesions on neuropeptide and dopamine receptor gene expression in the striatum-accumbens complex. Brain research. vol 797. issue 1. 1998-08-06. PMID:9630515. |
no differences were found between sham and lesion groups for enk, d1, subp, or gad65 mrna levels in the striatum or nucleus accumbens (nac). |
1998-08-06 |
2023-08-12 |
rat |
| C L Zuch, D J O'Mara, D A Cory-Slecht. Low-level lead exposure selectively enhances dopamine overflow in nucleus accumbens: an in vivo electrochemistry time course assessment. Toxicology and applied pharmacology. vol 150. issue 1. 1998-06-29. PMID:9630467. |
in vivo electrochemical measurements of potassium chloride-evoked da overflow and clearance were compared in dorsal striatum (str) (nigrostriatal system) and nucleus accumbens (nac)(mesolimbic system) of male rats after 11 weeks or 11 months of postweaning exposure to 0, 50, or 150 ppm pb acetate drinking solutions. |
1998-06-29 |
2023-08-12 |
rat |
| F S Hall, L S Wilkinson, T Humby, W Inglis, D A Kendall, C A Marsden, T W Robbin. Isolation rearing in rats: pre- and postsynaptic changes in striatal dopaminergic systems. Pharmacology, biochemistry, and behavior. vol 59. issue 4. 1998-06-26. PMID:9586842. |
isolation rearing of rats produces a behavioral syndrome indicative of altered dopamine (da) function in the nucleus accumbens (nac). |
1998-06-26 |
2023-08-12 |
rat |
| G Di Chiar. A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use. Journal of psychopharmacology (Oxford, England). vol 12. issue 1. 1998-06-23. PMID:9584969. |
such abnormal motivational learning would derive from the repetitive non-habituating property of drugs of abuse to activate da transmission phasically in the nucleus accumbens (nac) 'shell'. |
1998-06-23 |
2023-08-12 |
Not clear |
| M Yoshida, H Yokoo, K Mizoguchi, T Tanaka, H Emoto, M Tanak. NMDA- and MK801-induced changes in dopamine release are attenuated in kainic acid-lesioned nucleus accumbens of conscious rats: an in vivo microdialysis study. Brain research. vol 786. issue 1-2. 1998-06-12. PMID:9555028. |
local application of n-methyl-d-aspartate (nmda) and a nmda receptor antagonist, mk801 through the dialysis membrane into the nucleus accumbens (nac) caused a significant decrease and increase in extracellular dopamine (da) in the nac of conscious rats, respectively. |
1998-06-12 |
2023-08-12 |
rat |
| V M Pickel, A G Beck-Sickinger, J Chan, H A Weilan. Y1 receptors in the nucleus accumbens: ultrastructural localization and association with neuropeptide Y. Journal of neuroscience research. vol 52. issue 1. 1998-05-29. PMID:9556029. |
y1 receptors in the nucleus accumbens: ultrastructural localization and association with neuropeptide y. neuropeptide y (npy) is present in aspiny neurons in the nucleus accumbens (nac), which also contains moderate levels of ligand binding and mrna for the y1 receptor. |
1998-05-29 |
2023-08-12 |
rat |
| S M Nicola, R C Malenk. Modulation of synaptic transmission by dopamine and norepinephrine in ventral but not dorsal striatum. Journal of neurophysiology. vol 79. issue 4. 1998-05-27. PMID:9535946. |
although the ventral striatum (nucleus accumbens; nac) and dorsal striatum are associated with different behaviors, these structures are anatomically and physiologically similar. |
1998-05-27 |
2023-08-12 |
Not clear |
| Z L Kruk, S Cheeta, J Milla, R Muscat, J E Williams, P Willne. Real time measurement of stimulated dopamine release in the conscious rat using fast cyclic voltammetry: dopamine release is not observed during intracranial self stimulation. Journal of neuroscience methods. vol 79. issue 1. 1998-05-26. PMID:9531455. |
fast cyclic voltammetry (fcv) was used to measure real time release of electrically stimulated endogenous dopamine in the nucleus accumbens (nac) of conscious freely moving rats for up to 17 days. |
1998-05-26 |
2023-08-12 |
rat |