| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laurence L Miller, Michael D Leitl, Matthew L Banks, Bruce E Blough, S Stevens Negu. Effects of the triple monoamine uptake inhibitor amitifadine on pain-related depression of behavior and mesolimbic dopamine release in rats. Pain. vol 156. issue 1. 2015-09-30. PMID:25599313. |
similarly, in rats, intraperitoneal injection of dilute lactic acid (ip acid) serves as a chemical noxious stimulus to produce analgesic-reversible decreases in both (1) extracellular da levels in nucleus accumbens (nac) and (2) intracranial self-stimulation (icss), an operant behavior reliant on nac da. |
2015-09-30 |
2023-08-13 |
rat |
| Analía Valdomero, María C Perondi, Otto A Orsingher, Gabriel R Cuadr. Exogenous GM1 ganglioside increases accumbal BDNF levels in rats. Behavioural brain research. vol 278. 2015-09-28. PMID:25453740. |
this study was performed to investigate the possibility that gm1 may induce changes in bdnf levels in the nucleus accumbens (nac), a core structure in the brain's reward circuitry, of rats submitted to three conditioning sessions with cocaine (10 mg/kg, i.p.). |
2015-09-28 |
2023-08-13 |
rat |
| Staci E Engle, J Michael McIntosh, Ryan M Drena. Nicotine and ethanol cooperate to enhance ventral tegmental area AMPA receptor function via α6-containing nicotinic receptors. Neuropharmacology. vol 91. 2015-09-28. PMID:25484253. |
nicotine + ethanol co-exposure results in additive and/or synergistic effects in the ventral tegmental area (vta) to nucleus accumbens (nac) dopamine (da) pathway, but the mechanisms supporting this are unclear. |
2015-09-28 |
2023-08-13 |
mouse |
| Jukka Kupila, Olli Kärkkäinen, Virpi Laukkanen, Merja Häkkinen, Hannu Kautiainen, Jari Tiihonen, Markus Storvi. [³H]Ifenprodil binding in post-mortem brains of Cloninger type 1 and 2 alcoholics: a whole-hemisphere autoradiography study. Psychiatry research. vol 231. issue 3. 2015-09-24. PMID:25616726. |
previous studies indicate that early-onset cloninger type 2 alcoholics have an intact, responsive, dopaminergic system in the nucleus accumbens (nac), whereas type 1 alcoholics have dopaminergic defects. |
2015-09-24 |
2023-08-13 |
human |
| S K Nygard, A Klambatsen, B Balouch, V Quinones-Jenab, S Jena. Region and context-specific intracellular responses associated with cocaine-induced conditioned place preference expression. Neuroscience. vol 287. 2015-09-23. PMID:25522720. |
nucleus accumbens (nac) phosphorylated erk (perk) levels were increased after re-exposure to the cocaine-paired, but not the saline-paired chamber, regardless of whether or not cpp behavior was expressed. |
2015-09-23 |
2023-08-13 |
rat |
| Qiong Wang, Feng Shao, Weiwen Wan. Maternal separation produces alterations of forebrain brain-derived neurotrophic factor expression in differently aged rats. Frontiers in molecular neuroscience. vol 8. 2015-09-21. PMID:26388728. |
in this study, we investigated the effects of repeated ms (4 h per day from postnatal day (pnd) 1-21) on the brain-derived neurotrophic factor (bdnf) expression in the medial prefrontal cortex (mpfc), the nucleus accumbens (nac) and the hippocampus of male and female juvenile (pnd 21), adolescent (pnd 35) and young adult (pnd 56) wistar rats. |
2015-09-21 |
2023-08-13 |
rat |
| Helmut Prast, Ariane Hornick, Michaela M Kraus, Athineos Philipp. Origin of endogenous nitric oxide released in the nucleus accumbens under real-time in vivo conditions. Life sciences. vol 134. 2015-09-16. PMID:26006039. |
it is implicated in physiological and pathological processes within the striatum, mainly in the nucleus accumbens (nac). |
2015-09-16 |
2023-08-13 |
rat |
| Anna Sun, Dingding Zhuang, Huaqiang Zhu, Miaojun Lai, Weisheng Chen, Huifeng Liu, Fuqiang Zhang, Wenhua Zho. Decrease of phosphorylated CREB and ERK in nucleus accumbens is associated with the incubation of heroin seeking induced by cues after withdrawal. Neuroscience letters. vol 591. 2015-09-15. PMID:25711798. |
here we aim to explore the expression of p-creb and the p-erk, an upstream molecular of creb, in the nucleus accumbens (nac) in the incubation of heroin-seeking induced by cue after withdrawal. |
2015-09-15 |
2023-08-13 |
rat |
| Caroline Dias, David Dietz, Michelle Mazei-Robison, Haosheng Sun, Diane Damez-Werno, Deveroux Ferguson, Matthew Wilkinson, Jane Magida, Virginia Gao, Rachael Neve, Eric J Nestle. Dishevelled-2 regulates cocaine-induced structural plasticity and Rac1 activity in the nucleus accumbens. Neuroscience letters. vol 598. 2015-09-14. PMID:25957559. |
chronic cocaine exposure increases the density of dendritic spines on medium spiny neurons (msns), the predominant neuronal cell type of the nucleus accumbens (nac), a key brain reward region. |
2015-09-14 |
2023-08-13 |
Not clear |
| Eugene A Kiyatkin, Ken T Wakabayash. Parsing glucose entry into the brain: novel findings obtained with enzyme-based glucose biosensors. ACS chemical neuroscience. vol 6. issue 1. 2015-09-10. PMID:25490002. |
second, we present data on glucose responses induced in the nucleus accumbens (nac) by salient environmental stimuli and discuss the relationships between local neuronal activation and rapid glucose entry into brain tissue. |
2015-09-10 |
2023-08-13 |
rat |
| Ashley A Vena, Rueben A Gonzale. Temporal profiles dissociate regional extracellular ethanol versus dopamine concentrations. ACS chemical neuroscience. vol 6. issue 1. 2015-09-10. PMID:25537116. |
early studies demonstrated dissociations between the time courses of brain ethanol concentrations and dopaminergic responses in the nucleus accumbens (nac) elicited by acute ethanol administration. |
2015-09-10 |
2023-08-13 |
Not clear |
| Sora Shin, Obin Kwon, Jee In Kang, Somin Kwon, Sora Oh, Jiwon Choi, Chul Hoon Kim, Dong Goo Ki. mGluR5 in the nucleus accumbens is critical for promoting resilience to chronic stress. Nature neuroscience. vol 18. issue 7. 2015-09-09. PMID:26005851. |
lentiviral 'rescue' of mglur5 in the nucleus accumbens (nac) decreased these depression-like behaviors in mglur5(-/-) mice. |
2015-09-09 |
2023-08-13 |
mouse |
| Amy M Gancarz, Zi-Jun Wang, Gabrielle L Schroeder, Diane Damez-Werno, Kevin M Braunscheidel, Lauren E Mueller, Monica S Humby, Aaron Caccamise, Jennifer A Martin, Karen C Dietz, Rachael L Neve, David M Diet. Activin receptor signaling regulates cocaine-primed behavioral and morphological plasticity. Nature neuroscience. vol 18. issue 7. 2015-09-09. PMID:26030849. |
activin receptor signaling, including the transcription factor smad3, was upregulated in the rat nucleus accumbens (nac) shell following withdrawal from cocaine. |
2015-09-09 |
2023-08-13 |
rat |
| Stan B Floresc. The nucleus accumbens: an interface between cognition, emotion, and action. Annual review of psychology. vol 66. 2015-09-09. PMID:25251489. |
nearly 40 years of research on the function of the nucleus accumbens (nac) has provided a wealth of information on its contributions to behavior but has also yielded controversies and misconceptions regarding these functions. |
2015-09-09 |
2023-08-13 |
Not clear |
| Alexander Frolov, Cruz Reyes-Vasquez, Nachum Dafn. Behavioral and neuronal recording of the nucleus accumbens in adolescent rats following acute and repetitive exposure to methylphenidate. Journal of neurophysiology. vol 113. issue 1. 2015-09-07. PMID:25318764. |
the nucleus accumbens (nac) has been shown to play a key role in the brain's response to methylphenidate (mpd). |
2015-09-07 |
2023-08-13 |
rat |
| Christina N Nona, Meaghan C Creed, Clement Hamani, José N Nobreg. Effects of high-frequency stimulation of the nucleus accumbens on the development and expression of ethanol sensitization in mice. Behavioural pharmacology. vol 26. issue 1-2. 2015-09-03. PMID:24642732. |
the present study examined the effects of hfs of the nucleus accumbens (nac), an area that has been shown to be important for sensitization to several psychostimulants, on the development and expression of etoh sensitization. |
2015-09-03 |
2023-08-12 |
mouse |
| Hiroko Ikeda, Kazunori Adachi, Satoshi Fujita, Katsunori Tomiyama, Tadashi Saigusa, Masayuki Kobayashi, Noriaki Koshikawa, John L Waddingto. Investigating complex basal ganglia circuitry in the regulation of motor behaviour, with particular focus on orofacial movement. Behavioural pharmacology. vol 26. issue 1-2. 2015-09-03. PMID:25485640. |
we consider these mechanisms and their efferent systems, including spiralling, feed-forward striato-nigro-striatal circuitry, involving the dorsal and ventral striatum and the nucleus accumbens (nac) core and shell. |
2015-09-03 |
2023-08-13 |
mouse |
| Jackson J Cone, Jamie D Roitman, Mitchell F Roitma. Ghrelin regulates phasic dopamine and nucleus accumbens signaling evoked by food-predictive stimuli. Journal of neurochemistry. vol 133. issue 6. 2015-09-02. PMID:25708523. |
here we show that cue-evoked changes in both nucleus accumbens (nac) dopamine (da) and nac cell activity are modulated by intra-cranial infusions of the stomach hormone ghrelin--a hormone known to act centrally to promote food intake. |
2015-09-02 |
2023-08-13 |
rat |
| Jackson J Cone, Jamie D Roitman, Mitchell F Roitma. Ghrelin regulates phasic dopamine and nucleus accumbens signaling evoked by food-predictive stimuli. Journal of neurochemistry. vol 133. issue 6. 2015-09-02. PMID:25708523. |
these food-predictive cues evoke brief (phasic) changes in nucleus accumbens (nac) dopamine concentration and in the activity of individual nac neurons. |
2015-09-02 |
2023-08-13 |
rat |
| Zhong-ze Lou, Ling-hong Chen, Hui-feng Liu, Lie-min Ruan, Wen-hua Zho. Blockade of mGluR5 in the nucleus accumbens shell but not core attenuates heroin seeking behavior in rats. Acta pharmacologica Sinica. vol 35. issue 12. 2015-08-25. PMID:25399651. |
glutamatergic neurotransmission in the nucleus accumbens (nac) is crucial for the relapse to heroin seeking. |
2015-08-25 |
2023-08-13 |
rat |