| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Wang, Lulin Dai, Yijie Lai, Fengting Wang, Yingying Zhang, Yuhan Wang, Dianyou Li, Shikun Zhan, Liuguan Bian, Bomin Su. Parameter-based analysis of clinical efficacy of combined bed nucleus of the stria terminalis-nucleus accumbens deep brain stimulation for treatment-resistant depression. Journal of neurosurgery. 2024-01-12. PMID:38215436. |
this study carried out dual-target combined stimulation of the bed nucleus of the stria terminalis (bnst) and nucleus accumbens (nac) to investigate the effectiveness of the treatment for trd patients. |
2024-01-12 |
2024-01-15 |
Not clear |
| Seyedeh-Najmeh Katebi, Anahita Torkaman-Boutorabi, Esmail Riahi, Abbas Haghparas. N-acetylcysteine attenuates accumbal core neuronal activity in response to morphine in the reinstatement of morphine CPP in morphine extinguished rats. Progress in neuro-psychopharmacology & biological psychiatry. 2024-01-12. PMID:38215930. |
the nucleus accumbens (nac) plays a crucial role in the brain's reward system, with the nucleus accumbens core (nacore) specifically implicated in compulsive drug seeking and relapse. |
2024-01-12 |
2024-01-15 |
rat |
| Cameron J Davidson, John H Hannigan, Shane A Perrine, Scott E Bowe. Abuse-like toluene exposure during early adolescence alters subsequent ethanol and cocaine behavioral effects and brain monoamines in male mice. Neurotoxicology and teratology. 2024-01-10. PMID:38199311. |
analysis of monoamines and their metabolites using high pressure liquid chromatography (hplc) within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dstr), and ventral tegmental area (vta) revealed subtle effects on monoamine or metabolite levels following cumulative dosing that varied by drug (cocaine and ethanol) and abstinence duration. |
2024-01-10 |
2024-01-13 |
mouse |
| Milan D Valyear, Alexa Brown, Ghislaine Deyab, Franz R Villaruel, Soraya Lahlou, Nina Caporicci-Dinucci, Nadia Chaudhr. Augmenting glutamatergic, but not dopaminergic, activity in the nucleus accumbens shell disrupts responding to a discrete alcohol cue in an alcohol context. The European journal of neuroscience. 2024-01-08. PMID:38185906. |
when conditioned cs responding was tested by presenting the cs without alcohol, we found that augmenting glutamatergic activity in the nucleus accumbens (nac) shell by microinfusing α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) reduced responding to an alcohol cs in an alcohol, but not neutral, context. |
2024-01-08 |
2024-01-10 |
rat |
| Timothy J Onofrychuk, Ashton L Heidt, Spencer N Orvold, Quentin Greba, John G Howlan. Nucleus accumbens core dopamine D2 receptors are required for performance of the odor span task in male rats. Psychopharmacology. 2024-01-06. PMID:38183429. |
the nucleus accumbens (nac) core gates motivationally relevant behavioral action sequences through afferents from cortical and subcortical brain regions. |
2024-01-06 |
2024-01-09 |
rat |
| Kaitlyn A Petersen, Wei Zong, Lauren M Depoy, Madeline R Scott, Vaishnavi G Shankar, Jennifer N Burns, Allison J Cerwensky, Sam-Moon Kim, Kyle D Ketchesin, George C Tseng, Colleen A McClun. Comparative rhythmic transcriptome profiling of human and mouse striatal subregions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-01-05. PMID:38182777. |
the human striatum can be subdivided into the caudate, putamen, and nucleus accumbens (nac). |
2024-01-05 |
2024-01-08 |
mouse |
| Marine Salery, Arthur Godino, Yu Qing Xu, John F Fullard, Romain Durand-de Cuttoli, Alexa R LaBanca, Leanne M Holt, Scott J Russo, Panos Roussos, Eric J Nestle. Transcriptional correlates of cocaine-associated learning in striatal ARC ensembles. bioRxiv : the preprint server for biology. 2024-01-03. PMID:38168167. |
previous work demonstrates the importance of sparse neuronal populations - called neuronal ensembles - in associative learning and cocaine seeking, but it remains unknown whether the encoding vs. retrieval of cocaine-associated memories involves similar or distinct mechanisms of ensemble activation and reactivation in nucleus accumbens (nac). |
2024-01-03 |
2024-01-06 |
Not clear |
| Kenneth Blum, Thomas Mclaughlin, Mark S Gold, Marjorie C Gondre-Lewis, Panayotis K Thanos, Igor Elman, David Baron, Abdalla Bowirrat, Debamyla Barh, Jag Khalsa, Colin Hanna, Nicole Jafari, Foojan Zeine, Eric R Braverman, Catherine Dennen, Milan T Makale, Miles Makale, Keerthy Sunder, Kevin T Murphy, Rajendra D Badgaiya. Are We Getting High Cause the Thrill is Gone? Journal of addiction psychiatry. vol 7. issue 1. 2024-01-02. PMID:38164471. |
analogously, it is of importance to acknowledge that the cumulative discharge of dopamine, governed by the nucleus accumbens (nac) and modulated by an array of additional neurotransmitters, constitutes a cornerstone of an individual's overall well-being. |
2024-01-02 |
2024-01-05 |
Not clear |
| Emanuele Claudio Latagliata, Cristina Orsini, Simona Cabib, Francesca Biagioni, Francesco Fornai, Stefano Puglisi-Allegr. Prefrontal Dopamine in Flexible Adaptation to Environmental Changes: A Game for Two Players. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137410. |
the reviewed findings point to a role of catecholaminergic transmission in the medial prefrontal cortex (mpfc) in modulating da's availability in the nucleus accumbens (nac), as well as a role of nac da in modulating the motivational value of natural and conditioned stimuli. |
2023-12-23 |
2023-12-25 |
Not clear |
| Ki Bum Um, Soyoung Kwak, Sun-Ha Cheon, JuHyun Kim, Su-Kyeong Hwan. AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137504. |
the core symptoms of asd are associated with deficits in mesocorticolimbic dopamine pathways that project from the ventral tegmental area (vta) to the nucleus accumbens (nac) and medial prefrontal cortex (mpfc). |
2023-12-23 |
2023-12-25 |
mouse |
| Jennifer E Zachry, Munir Gunes Kutlu, Hye Jean Yoon, Michael Z Leonard, Maxime Chevée, Dev D Patel, Anthony Gaidici, Veronika Kondev, Kimberly C Thibeault, Rishik Bethi, Jennifer Tat, Patrick R Melugin, Atagun U Isiktas, Max E Joffe, Denise J Cai, P Jeffrey Conn, Brad A Grueter, Erin S Calipar. D1 and D2 medium spiny neurons in the nucleus accumbens core have distinct and valence-independent roles in learning. Neuron. 2023-12-22. PMID:38134921. |
at the core of value-based learning is the nucleus accumbens (nac). |
2023-12-22 |
2023-12-25 |
mouse |
| Julian Cheron, Leonardo Beccari, Perrine Hagué, Romain Icick, Chloé Despontin, Teresa Carusone, Matthieu Defrance, Sagar Bhogaraju, Elena Martin-Garcia, Roberto Capellan, Rafael Maldonado, Florence Vorspan, Jérôme Bonnefont, Alban de Kerchove d'Exaerd. USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in cocaine use disorder. Nature communications. vol 14. issue 1. 2023-12-20. PMID:38123574. |
while histone modifications such as methylation and acetylation have been studied in the ventral tegmental area and nucleus accumbens (nac), the role of h2a monoubiquitination remains unknown. |
2023-12-20 |
2023-12-23 |
Not clear |
| Oyku Dinckol, Noah Harris Wenger, Jennifer E Zachry, Munir Gunes Kutl. Nucleus accumbens core single cell ensembles bidirectionally respond to experienced versus observed aversive events. Scientific reports. vol 13. issue 1. 2023-12-19. PMID:38114559. |
in this study, we recorded single cell activity patterns of nucleus accumbens (nac) core neurons using in vivo optical imaging of calcium transients via miniature scopes. |
2023-12-19 |
2023-12-23 |
Not clear |
| Shingo Nakajima, Geneviève Demers, Arturo Israel Machuca-Parra, Zahra Dashtehei Pour, Diane Bairamian, Khalil Bouyakdan, Alexandre Fisette, Anita Kabahizi, Josephine Robb, Demetra Rodaros, Cyril Laurent, Guillaume Ferreira, Nathalie Arbour, Thierry Alquier, Stephanie Fulto. Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors. Journal of neuroinflammation. vol 20. issue 1. 2023-12-19. PMID:38111048. |
we found gpr120 mrna to be enriched in both murine and human microglia, and in situ hybridization revealed gpr120 expression in microglia of the nucleus accumbens (nac) in mice. |
2023-12-19 |
2023-12-21 |
mouse |
| Brandon Taraku, Joana R Loureiro, Ashish K Sahib, Artemis Zavaliangos-Petropulu, Noor Al-Sharif, Amber Leaver, Benjamin Wade, Shantanu Joshi, Roger P Woods, Randall Espinoza, Katherine L Nar. Ketamine treatment modulates habenular and nucleus accumbens static and dynamic functional connectivity in major depression. medRxiv : the preprint server for health sciences. 2023-12-18. PMID:38106178. |
dysfunctional reward processing in major depressive disorder (mdd) involves functional circuitry of the habenula (hb) and nucleus accumbens (nac). |
2023-12-18 |
2023-12-21 |
human |
| Li Niu, Mengnan Hao, Yanhong Wang, Kai Wu, Chengdong Yuan, Yu Zhang, Jie Zhang, Xiaoli Liang, Yi Zhan. Dopamine D2-receptor neurons in nucleus accumbens regulate sevoflurane anesthesia in mice. Frontiers in molecular neuroscience. vol 16. 2023-12-13. PMID:38089676. |
as a result, this study aimed to explore the involvement of dopamine d2 receptor (d2r) expressing neurons located in the nucleus accumbens (nac), a critical nucleus governing sleep-wake regulation, in sevoflurane anesthesia. |
2023-12-13 |
2023-12-17 |
mouse |
| Caroline S Johnson, Andrew D Chapp, Erin B Lind, Mark J Thomas, Paul G Mermelstei. Sex differences in mouse infralimbic cortex projections to the nucleus accumbens shell. Biology of sex differences. vol 14. issue 1. 2023-12-12. PMID:38082417. |
the nucleus accumbens (nac) is an important region in motivation and reward. |
2023-12-12 |
2023-12-17 |
mouse |
| Oualid Abboussi, Zmarak Ahmad Khan, Hind Ibork, Simo S Zulu, William Daniels, Khalid Taghzouti, Tim G Hale. CB2 agonist mitigates cocaine-induced reinstatement of place preference and modulates the inflammatory response in mice. Behavioural pharmacology. 2023-12-12. PMID:38085651. |
specifically, jwh-133 administration was found to upregulate Δ-fosb expression in the nucleus accumbens (nac), elevate cx3cl1 levels in both the ventral tegmental area and prefrontal cortex (pfc), and concurrently reduce il-1β expression in the pfc and nac among cocaine-treated animals. |
2023-12-12 |
2023-12-17 |
mouse |
| Shelley M Warlow, Sarthak M Singhal, Nick G Hollon, Lauren Faget, Dina S Dowlat, Vivien Zell, Avery C Hunker, Larry S Zweifel, Thomas S Hnask. Mesoaccumbal glutamate neurons drive reward via glutamate release but aversion via dopamine co-release. Neuron. 2023-12-12. PMID:38086374. |
ventral tegmental area (vta) projections to the nucleus accumbens (nac) drive reward-related motivation. |
2023-12-12 |
2023-12-17 |
mouse |
| Yann Ehinger, Sophie Laguesse, Khanhky Phamluong, Alexandra Salvi, Zachary W Hoisington, Drishti Soneja, Yoshitaka J Sei, Ken Nakamura, Dorit Ro. Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis. bioRxiv : the preprint server for biology. 2023-12-11. PMID:38076984. |
we report that activation of mtorc1 in the nucleus accumbens (nac) of mice consuming alcohol promotes the translation of microrna (mir) machinery components and the upregulation of micrornas (mirs) expression including mir34a-5p. |
2023-12-11 |
2023-12-17 |
mouse |